A bout of aerobic exercise in the heat increases carbohydrate use but does not enhance the disposal of an oral glucose load, in healthy active individuals
Am J Physiol Endocrinol Metab. 2024 Apr 3. doi: 10.1152/ajpendo.00312.2023. Online ahead of print.ABSTRACTWe investigated if a bout of exercise in a hot environment (HEAT) would reduce the postprandial hyperglycemia induced by glucose ingestion. The hypothesis was that HEAT stimulating glycogen use would increase the disposal of the ingested glucose (i.e., OGTT; 75 g of glucose). Separated by at least 1 week, nine young-healthy individuals underwent three trials after an overnight fast in a randomized order. Two trials included 50 min of pedaling at 58±5% VO2MAX either in a thermoneutral (21±1ºC; NEUTRAL) or in a hot en...
Source: Am J Physiol Endocri... - April 3, 2024 Category: Endocrinology Authors: Ricardo Mora-Rodriguez Alfonso Moreno-Caba ñas Laura Álvarez-Jimenez Diego Mora-Gonzalez Juan Fernando Ortega Felix Morales-Palomo Source Type: research

A bout of aerobic exercise in the heat increases carbohydrate use but does not enhance the disposal of an oral glucose load, in healthy active individuals
Am J Physiol Endocrinol Metab. 2024 Apr 3. doi: 10.1152/ajpendo.00312.2023. Online ahead of print.ABSTRACTWe investigated if a bout of exercise in a hot environment (HEAT) would reduce the postprandial hyperglycemia induced by glucose ingestion. The hypothesis was that HEAT stimulating glycogen use would increase the disposal of the ingested glucose (i.e., OGTT; 75 g of glucose). Separated by at least 1 week, nine young-healthy individuals underwent three trials after an overnight fast in a randomized order. Two trials included 50 min of pedaling at 58±5% VO2MAX either in a thermoneutral (21±1ºC; NEUTRAL) or in a hot en...
Source: American Journal of Physiology. Endocrinology and Metabolism - April 3, 2024 Category: Physiology Authors: Ricardo Mora-Rodriguez Alfonso Moreno-Caba ñas Laura Álvarez-Jimenez Diego Mora-Gonzalez Juan Fernando Ortega Felix Morales-Palomo Source Type: research

A bout of aerobic exercise in the heat increases carbohydrate use but does not enhance the disposal of an oral glucose load, in healthy active individuals
Am J Physiol Endocrinol Metab. 2024 Apr 3. doi: 10.1152/ajpendo.00312.2023. Online ahead of print.ABSTRACTWe investigated if a bout of exercise in a hot environment (HEAT) would reduce the postprandial hyperglycemia induced by glucose ingestion. The hypothesis was that HEAT stimulating glycogen use would increase the disposal of the ingested glucose (i.e., OGTT; 75 g of glucose). Separated by at least 1 week, nine young-healthy individuals underwent three trials after an overnight fast in a randomized order. Two trials included 50 min of pedaling at 58±5% VO2MAX either in a thermoneutral (21±1ºC; NEUTRAL) or in a hot en...
Source: Am J Physiol Endocri... - April 3, 2024 Category: Endocrinology Authors: Ricardo Mora-Rodriguez Alfonso Moreno-Caba ñas Laura Álvarez-Jimenez Diego Mora-Gonzalez Juan Fernando Ortega Felix Morales-Palomo Source Type: research

Comparison of energy requirement estimation using activity record or accelerometer with doubly labeled water method in collegiate male sprinters
Track and field sprinters must obtain an optimal body composition to improve sprint performance. To successfully change body composition, it is important to evaluate the estimated energy requirements (EER) and fluctuations in total energy expenditure (TEE). However, methods to accurately evaluate the EER and TEE in sprinters have not been fully investigated. The aim of this study was to compare currently used methods with the doubly labeled water (DLW) method, which is currently the gold standard for evaluating EER and TEE. (Source: Clinical Nutrition ESPEN)
Source: Clinical Nutrition ESPEN - April 3, 2024 Category: Nutrition Authors: Yuki Shimamura, Ryusei Takemura, Kensuke Iwanami, Daisuke Yamamoto, Hiroyuki Sagayama, Kaito Iwayama Tags: Original article Source Type: research

Optimising oncology drug expenditure in Ireland
AbstractA combination of improvements in patient survival, increasing treatment duration, and the development of more expensive agents has led to a doubling of per-capita spending on cancer medicines in Ireland (2008 –2018). Despite this, access to new drugs is poor in comparison to other EU countries. We examine methods to optimise oncology drug spending to facilitate access to newer anticancer agents. Key targets for spending optimisation (biosimilar use, clinical trials and expanded access programs, waste r eduction, avoidance of futile treatment, and altered drug scheduling) were identified through an exploratory ana...
Source: Irish Journal of Medical Science - April 3, 2024 Category: General Medicine Source Type: research

The Financial Implications of a Single-Use Device Reprocessing Program at a Tertiary Referral Center Surgical Department
Am Surg. 2024 Apr 1:31348241241679. doi: 10.1177/00031348241241679. Online ahead of print.ABSTRACTThe operating room has been identified as one of the primary contributors to waste and energy expenditure in the health care system. The primary objective of our study was to evaluate the efficacy of single-use device reprocessing and report the cost savings, waste diversion, and reduction in carbon emissions. Data was collected from January 2021 to April 2023. Medline collected the data for analysis and converted it from an Excel file format to SPSS (Version 27) for analysis. Descriptive frequencies were used for data analysi...
Source: The American Surgeon - April 2, 2024 Category: Surgery Authors: Katherine Englander Kaitlyn Cox Teagen Smith Adbul Diab Samer Ganam Joseph Sujka Christopher DuCoin Source Type: research

The Financial Implications of a Single-Use Device Reprocessing Program at a Tertiary Referral Center Surgical Department
Am Surg. 2024 Apr 1:31348241241679. doi: 10.1177/00031348241241679. Online ahead of print.ABSTRACTThe operating room has been identified as one of the primary contributors to waste and energy expenditure in the health care system. The primary objective of our study was to evaluate the efficacy of single-use device reprocessing and report the cost savings, waste diversion, and reduction in carbon emissions. Data was collected from January 2021 to April 2023. Medline collected the data for analysis and converted it from an Excel file format to SPSS (Version 27) for analysis. Descriptive frequencies were used for data analysi...
Source: The American Surgeon - April 2, 2024 Category: Surgery Authors: Katherine Englander Kaitlyn Cox Teagen Smith Adbul Diab Samer Ganam Joseph Sujka Christopher DuCoin Source Type: research

From Scientific Research to Practical Implementations: Applications to Improve Data Quality in Child Welfare
AbstractChild welfare decisions have life-impacting consequences which, often times, are underpinned by limited or inadequate data and poor quality. Though research of data quality has gained popularity and made advancements in various practical areas, it has not made significant inroads for child welfare fields or data systems. Poor data quality can hinder service decision-making, impacting child behavioral health and well-being as well as increasing unnecessary expenditure of time and resources. Poor data quality can also undermine the validity of research and slow policymaking processes. The purpose of this commentary i...
Source: The Journal of Behavioral Health Services and Research - April 1, 2024 Category: Psychiatry & Psychology Source Type: research

Capacity for the management of kidney failure in the International Society of Nephrology South Asia region: report from the 2023 ISN Global Kidney Health Atlas (ISN-GKHA)
The South Asia region is facing a high burden of chronic kidney disease (CKD) with limited health resources and low expenditure on health care. In addition to the burden of CKD and kidney failure from traditional risk factors, CKD of unknown etiologies from India and Sri Lanka compounds the challenges of optimal management of CKD in the region. From the third edition of the International Society of Nephrology Global Kidney Health Atlas (ISN-GKHA), we present the status of CKD burden, infrastructure, funding, resources, and health care personnel using the World Health Organization ’s building blocks for health systems in ...
Source: Kidney International Supplements - April 1, 2024 Category: Urology & Nephrology Authors: Eranga Wijewickrama, Muhammad Rafiqul Alam, Divya Bajpai, Smita Divyaveer, Arpana Iyengar, Vivek Kumar, Ahad Qayyum, Shankar Prasad Yadav, Manjusha Yadla, Silvia Arruebo, Aminu K. Bello, Fergus J. Caskey, Sandrine Damster, Jo-Ann Donner, Vivekanand Jha, D Tags: ISN Public Affairs Source Type: research

Update on variability in organization and structures of kidney care across world regions
Globally, the number of people suffering from kidney disease is approaching 1 billion.1 This estimate is almost twice the number of people living with diabetes mellitus2 in 2021, and more than 20 times the number of people living with the human immunodeficiency virus (HIV) in 2022.3 Kidney disease recently has been ranked among the top-10 leading causes of death worldwide by the World Health Organization (WHO).4 Progression of chronic kidney disease (CKD) to kidney failure is associated with poor outcomes, including loss of life years, catastrophic health expenditures, reduced quality of life, and excess mortality. (Source...
Source: Kidney International Supplements - April 1, 2024 Category: Urology & Nephrology Authors: Ikechi G. Okpechi, Aminu K. Bello, Adeera Levin, David W. Johnson Tags: Introduction Source Type: research

Measured Resting Energy Expenditure and Predicted Basal Metabolic Rate Early After Left Ventricular Assist Device Implantation
Purpose: Fat free mass (FFM) increases over the first 6 months of left ventricular assist device (LVAD) support for patients with advanced heart failure with reduced ejection fraction (HFrEF), but concurrent resting energy expenditure (REE) and predicted basal metabolic rate (BMR) changes have not been studied. We hypothesized that measured REE (adjusted for FFM which is the major determinant of metabolic rate) would be highest at the baseline of LVAD implantation, when the HFrEF syndrome was most active. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , B. Sweigart, S. Hummel, J. Chery, E. Saltzman, A. Vest Source Type: research

Retraction Note: Asymmetric effect of FDI and public expenditure on population health: new evidence from Pakistan based on non-linear ARDL
Environ Sci Pollut Res Int. 2024 Apr 1. doi: 10.1007/s11356-024-33139-7. Online ahead of print.NO ABSTRACTPMID:38556606 | DOI:10.1007/s11356-024-33139-7 (Source: Environmental Science and Pollution Research International)
Source: Environmental Science and Pollution Research International - March 31, 2024 Category: Environmental Health Authors: Saif Ur Rahman Imran Sharif Chaudhry Muhammad Saeed Meo Salman Maqsood Sheikh Sadia Idrees Source Type: research

Contribution of high-technology procedures to public healthcare expenditures: the case of ischemic heart disease in Portugal, 2002 –2015
AbstractThe magnitude of the impact of technological innovations on healthcare expenditure is unclear. This paper estimated the impact of high-technology procedures on public healthcare expenditure for patients with ischemic heart disease (IHD) in Portugal. The Blinder –Oaxaca decomposition method was applied to Portuguese NHS administrative data for IHD discharges during two periods, 2008–2015 vs. 2002–2007 (N = 434,870). We modelled per episode healthcare expenditures on the introduction of new technologies, adjusting for GDP, patient age, and comorbid ities. The per episode healthcare expenditure was significa...
Source: International Journal of Health Care Finance and Economics - March 29, 2024 Category: Health Management Source Type: research

Treated versus self-reported prevalence of chronic pain and costs of patients' health services utilization: a population-based study of health administrative databases
DISCUSSION: Our findings suggest that the economic burden of CP is considerable and that many people with self-reported CP do not use the public healthcare services. This can be multifactorial, including lack of availability and accessibility of publicly funded services, people's lack of awareness of available services, lower utilization due to COVID-19 pandemic, and reliance on self-management, private services, and alternative treatments. Further studies are warranted to inform future policies and health system initiatives aiming to reduce the burden of CP and improve lives of people living with it.PMID:38545500 | PMC:PM...
Source: Pain Physician - March 28, 2024 Category: Anesthesiology Authors: Nguyen Xuan Thanh Elena Lopatina Lori S Montgomery Magali Robert Robert L Tanguay Tracy Wasylak Source Type: research

Cost and value of cancer medicines in a single-payer public health system in Ontario, Canada: a cross-sectional study
We describe temporal trends in expenditure on cancer medicines within the single-payer health system of Ontario, Canada, and the extent of clinical benefit these treatments offer.METHODS: In this cross-sectional study, we identified cancer medicines and expenditures from formularies and costing databases (the New Drug Funding Program, Ontario Drug Benefit Program, and The High-Cost Therapy Funding Program) during 10 consecutive years (April 1, 2012, to March 31, 2022) in Ontario, Canada. For intravenous medicines, we applied the European Society for Medical Oncology Magnitude of Clinical Benefit Scale (ESMO-MCBS) to identi...
Source: Cancer Control - March 28, 2024 Category: Cancer & Oncology Authors: Joseph C Del Paggio Rohini Naipaul Scott Gavura Rebecca E Mercer Rachel Koven Bishal Gyawali Brooke E Wilson Christopher M Booth Source Type: research