Government Fiscal Decentralization and Haze and Carbon Reduction: Evidence from the Fiscal Province-Managing-County Reform
Environ Res. 2024 Apr 26:119020. doi: 10.1016/j.envres.2024.119020. Online ahead of print.ABSTRACTGovernment governance reform is not only a vital motivation for high economic quality but also an important factor in stimulating the government's environmental governance responsibility. The article empirically examines the fiscal Province-Managing-County (PMC) pilot reform on the synergic governance of haze and carbon reduction and its mechanism. The results show that the policy helps to realize the synergic governance of haze and carbon reduction, and the reform of fiscal Province-Managing-County promotes regional haze and ...
Source: Environmental Research - April 28, 2024 Category: Environmental Health Authors: Hong Xu Yukun Li Weifen Lin Yang Li Source Type: research
Impaired Fibroblast Growth Factor 21 (FGF21) Associated with Visceral Adiposity Leads to Insulin Resistance: The Core Defect in Diabetes Mellitus
Curr Diabetes Rev. 2024 Apr 26. doi: 10.2174/0115733998265915231116043813. Online ahead of print.ABSTRACTThe Central nervous system (CNS) is the prime regulator of signaling pathways whose function includes regulation of food intake (consumption), energy expenditure, and other metabolic responses like glycolysis, gluconeogenesis, fatty acid oxidation, and thermogenesis that have been implicated in chronic inflammatory disorders. Type 2 diabetes mellitus (T2DM) and obesity are two metabolic disorders that are linked together and have become an epidemic worldwide, thus raising significant public health concerns. Fibroblast g...
Source: Current Diabetes Reviews - April 27, 2024 Category: Endocrinology Authors: Unnati Jain Priyanka Srivastava Ashwani Sharma Subrata Sinha Surabhi Johari Source Type: research
Impaired Fibroblast Growth Factor 21 (FGF21) Associated with Visceral Adiposity Leads to Insulin Resistance: The Core Defect in Diabetes Mellitus
Curr Diabetes Rev. 2024 Apr 26. doi: 10.2174/0115733998265915231116043813. Online ahead of print.ABSTRACTThe Central nervous system (CNS) is the prime regulator of signaling pathways whose function includes regulation of food intake (consumption), energy expenditure, and other metabolic responses like glycolysis, gluconeogenesis, fatty acid oxidation, and thermogenesis that have been implicated in chronic inflammatory disorders. Type 2 diabetes mellitus (T2DM) and obesity are two metabolic disorders that are linked together and have become an epidemic worldwide, thus raising significant public health concerns. Fibroblast g...
Source: Current Diabetes Reviews - April 27, 2024 Category: Endocrinology Authors: Unnati Jain Priyanka Srivastava Ashwani Sharma Subrata Sinha Surabhi Johari Source Type: research
Impaired Fibroblast Growth Factor 21 (FGF21) Associated with Visceral Adiposity Leads to Insulin Resistance: The Core Defect in Diabetes Mellitus
Curr Diabetes Rev. 2024 Apr 26. doi: 10.2174/0115733998265915231116043813. Online ahead of print.ABSTRACTThe Central nervous system (CNS) is the prime regulator of signaling pathways whose function includes regulation of food intake (consumption), energy expenditure, and other metabolic responses like glycolysis, gluconeogenesis, fatty acid oxidation, and thermogenesis that have been implicated in chronic inflammatory disorders. Type 2 diabetes mellitus (T2DM) and obesity are two metabolic disorders that are linked together and have become an epidemic worldwide, thus raising significant public health concerns. Fibroblast g...
Source: Current Diabetes Reviews - April 27, 2024 Category: Endocrinology Authors: Unnati Jain Priyanka Srivastava Ashwani Sharma Subrata Sinha Surabhi Johari Source Type: research
Impaired Fibroblast Growth Factor 21 (FGF21) Associated with Visceral Adiposity Leads to Insulin Resistance: The Core Defect in Diabetes Mellitus
Curr Diabetes Rev. 2024 Apr 26. doi: 10.2174/0115733998265915231116043813. Online ahead of print.ABSTRACTThe Central nervous system (CNS) is the prime regulator of signaling pathways whose function includes regulation of food intake (consumption), energy expenditure, and other metabolic responses like glycolysis, gluconeogenesis, fatty acid oxidation, and thermogenesis that have been implicated in chronic inflammatory disorders. Type 2 diabetes mellitus (T2DM) and obesity are two metabolic disorders that are linked together and have become an epidemic worldwide, thus raising significant public health concerns. Fibroblast g...
Source: Current Diabetes Reviews - April 27, 2024 Category: Endocrinology Authors: Unnati Jain Priyanka Srivastava Ashwani Sharma Subrata Sinha Surabhi Johari Source Type: research
Impaired Fibroblast Growth Factor 21 (FGF21) Associated with Visceral Adiposity Leads to Insulin Resistance: The Core Defect in Diabetes Mellitus
Curr Diabetes Rev. 2024 Apr 26. doi: 10.2174/0115733998265915231116043813. Online ahead of print.ABSTRACTThe Central nervous system (CNS) is the prime regulator of signaling pathways whose function includes regulation of food intake (consumption), energy expenditure, and other metabolic responses like glycolysis, gluconeogenesis, fatty acid oxidation, and thermogenesis that have been implicated in chronic inflammatory disorders. Type 2 diabetes mellitus (T2DM) and obesity are two metabolic disorders that are linked together and have become an epidemic worldwide, thus raising significant public health concerns. Fibroblast g...
Source: Current Diabetes Reviews - April 27, 2024 Category: Endocrinology Authors: Unnati Jain Priyanka Srivastava Ashwani Sharma Subrata Sinha Surabhi Johari Source Type: research
Impaired Fibroblast Growth Factor 21 (FGF21) Associated with Visceral Adiposity Leads to Insulin Resistance: The Core Defect in Diabetes Mellitus
Curr Diabetes Rev. 2024 Apr 26. doi: 10.2174/0115733998265915231116043813. Online ahead of print.ABSTRACTThe Central nervous system (CNS) is the prime regulator of signaling pathways whose function includes regulation of food intake (consumption), energy expenditure, and other metabolic responses like glycolysis, gluconeogenesis, fatty acid oxidation, and thermogenesis that have been implicated in chronic inflammatory disorders. Type 2 diabetes mellitus (T2DM) and obesity are two metabolic disorders that are linked together and have become an epidemic worldwide, thus raising significant public health concerns. Fibroblast g...
Source: Current Diabetes Reviews - April 27, 2024 Category: Endocrinology Authors: Unnati Jain Priyanka Srivastava Ashwani Sharma Subrata Sinha Surabhi Johari Source Type: research
Factors influencing medical expenditures in patients with unresolved facial palsy and pharmacoeconomic analysis of upper eyelid lid loading with gold and platinum weights compared to tarsorrhaphy
There are no standards in diagnostic and therapeutic approaches to eye care in incomplete eyelid closure due to unresolved facial palsy (FP). Loading of the upper eyelid (UELL) with gold weights (GWs) or plati... (Source: Health Economics Review)
Source: Health Economics Review - April 27, 2024 Category: Health Management Authors: Izabela Nowak-Gospodarowicz, Marcin Gospodarowicz and Marek R ękas Tags: Research Source Type: research
Energy expenditure related biomarkers following bariatric surgery: a prospective six-month cohort study
Mitochondria dysfunction is one of the major causes of insulin resistance, and other countless complications of obesity. PGC-1 α, and UCP-2 play key roles in energy expenditure regulation in the mitochondrial t... (Source: BMC Surgery)
Source: BMC Surgery - April 27, 2024 Category: Surgery Authors: Mahsa Hatami, Mohammad Hassan Javanbakht, Neda Haghighat, Zahra Sohrabi, Rahman Yavar, Abdolreza Pazouki and Gholamreza Mohammadi Farsani Tags: Research Source Type: research
A ferroptosis amplifier based on triple-enhanced lipid peroxides accumulation strategy for effective pancreatic cancer therapy
Biomaterials. 2024 Apr 21;309:122574. doi: 10.1016/j.biomaterials.2024.122574. Online ahead of print.ABSTRACTAs an iron dependent regulatory cell death process driven by excessive lipid peroxides (LPO), ferroptosis is recognized as a powerful weapon for pancreatic cancer (PC) therapy. However, the tumor microenvironment (TME) with hypoxia and elevated glutathione (GSH) expression not only inhibits LPO production, but also induces glutathione peroxidase 4 (GPX4) mediated LPO clearance, which greatly compromise the therapeutic outcomes of ferroptosis. To address these issues, herein, a novel triple-enhanced ferroptosis ampli...
Source: Biomaterials - April 26, 2024 Category: Materials Science Authors: Mengyao Chen Xiaohan Tong Yanting Sun Chunyan Dong Chen Li Chunhui Wang Minyi Zhang Yixuan Wen Pinting Ye Ruihao Li Jie Wan Shujing Liang Shuo Shi Source Type: research
A ferroptosis amplifier based on triple-enhanced lipid peroxides accumulation strategy for effective pancreatic cancer therapy
Biomaterials. 2024 Apr 21;309:122574. doi: 10.1016/j.biomaterials.2024.122574. Online ahead of print.ABSTRACTAs an iron dependent regulatory cell death process driven by excessive lipid peroxides (LPO), ferroptosis is recognized as a powerful weapon for pancreatic cancer (PC) therapy. However, the tumor microenvironment (TME) with hypoxia and elevated glutathione (GSH) expression not only inhibits LPO production, but also induces glutathione peroxidase 4 (GPX4) mediated LPO clearance, which greatly compromise the therapeutic outcomes of ferroptosis. To address these issues, herein, a novel triple-enhanced ferroptosis ampli...
Source: Biomaterials - April 26, 2024 Category: Materials Science Authors: Mengyao Chen Xiaohan Tong Yanting Sun Chunyan Dong Chen Li Chunhui Wang Minyi Zhang Yixuan Wen Pinting Ye Ruihao Li Jie Wan Shujing Liang Shuo Shi Source Type: research
Alzheimer ’s Disease and Related Dementias Diagnosis in the United States Among US-Born and Foreign-Born White, Black, Hispanic, and Asian Older Adults
AbstractTimely clinical diagnosis of Alzheimer ’s disease and related dementias (ADRD) is important for resource allocation, mitigating safety concerns, and improving quality of life. While studies have examined ADRD diagnosis disparities by race/ethnicity, few include its intersection with nativity. Our aims were to (1) estimate the odds of d iagnosed ADRD among US- and foreign-born racial/ethnic groups compared to US-born White older adults and (2) make comparisons by nativity within each racial/ethnic group. We linked 2000–2017 National Health Interview Survey (NHIS) and 2001–2018 Medical Expenditure Panel Survey ...
Source: Journal of Racial and Ethnic Health Disparities - April 26, 2024 Category: International Medicine & Public Health Source Type: research
Dementia Care in Rural Appalachia: Multilevel Analysis of Individual and County-level Factors
DISCUSSION AND IMPLICATIONS: Findings suggest that informal support in caring for the person living with dementia enables HCBS use in rural Appalachia. In contrast, limited geographic accessibility and service availability can impede HCBS use in rural regions. Policymakers are urged to allocate direct public funding to service providers to expand service availability in under-resourced rural regions.PMID:38661552 | DOI:10.1093/geront/gnae037 (Source: The Gerontologist)
Source: The Gerontologist - April 25, 2024 Category: Geriatrics Authors: Suyoung Nah Jyoti Savla Karen A Roberto Source Type: research
New insights into the roles of Irisin in diabetic cardiomyopathy and vascular diseases
Biomed Pharmacother. 2024 Apr 24;175:116631. doi: 10.1016/j.biopha.2024.116631. Online ahead of print.ABSTRACTDiabetes mellitus (DM) is a prevalent chronic disease in the 21st century due to increased lifespan and unhealthy lifestyle choices. Extensive research indicates that exercise can play a significant role in regulating systemic metabolism by improving energy metabolism and mitigating various metabolic disorders, including DM. Irisin, a well-known exerkine, was initially reported to enhance energy expenditure by indicating the browning of white adipose tissue (WAT) through peroxisome proliferator-activated receptor Î...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - April 25, 2024 Category: Drugs & Pharmacology Authors: Tiandong Zhang Qian Yi Wenhua Huang Jianguo Feng Huan Liu Source Type: research
Dementia Care in Rural Appalachia: Multilevel Analysis of Individual and County-level Factors
DISCUSSION AND IMPLICATIONS: Findings suggest that informal support in caring for the person living with dementia enables HCBS use in rural Appalachia. In contrast, limited geographic accessibility and service availability can impede HCBS use in rural regions. Policymakers are urged to allocate direct public funding to service providers to expand service availability in under-resourced rural regions.PMID:38661552 | DOI:10.1093/geront/gnae037 (Source: The Gerontologist)
Source: The Gerontologist - April 25, 2024 Category: Geriatrics Authors: Suyoung Nah Jyoti Savla Karen A Roberto Source Type: research
