A Comprehensive Review on GLP-1 Signaling Pathways in the Management of Diabetes Mellitus - Focus on the Potential Role of GLP-1 Receptors Agonists and Selenium Among Various Organ Systems
Curr Diabetes Rev. 2024 Apr 16. doi: 10.2174/0115733998287178240403055901. Online ahead of print.ABSTRACTDiabetes Mellitus develops when the body becomes unable to fuel its cells with glucose, which results in the accumulation of sugar excess in the bloodstream. Because it has diverse pathophysiological impacts on the body, diabetes mellitus represents a significant issue of concern in an attempt to find suitable treatment modalities and medications for afflicted diabetic patients. Glucagon-like peptide 1 (GLP-1) plays a pivotal role in the incretin effect, emerging as a prospective treatment for diabetes mellitus and a pr...
Source: Current Diabetes Reviews - April 17, 2024 Category: Endocrinology Authors: Ghinwa Barakat Ghaith Assi Hussein Khalil Sami El Khatib Source Type: research
Exploring the Therapeutic Potential of Anti-VEGF Drugs for the Management of Diabetic Retinopathy: An Overview
Curr Diabetes Rev. 2024 Apr 16. doi: 10.2174/0115733998294968240405091023. Online ahead of print.ABSTRACTThe discovery of antivascular endothelial growth factor medications has resulted in a substantial change in diabetic retinopathy treatment. The most common cause of diabetic retinopathy blindness is Diabetic Macular Edema. The pathophysiology of Diabetic Macular Edema is thought to include the well-known pro-angiogenic and pro-permeability factor vascular endothelial growth factor. Over the past decade, drugs that impede the functions of vascular endothelial growth factors have established themselves as a standard-of-ca...
Source: Current Diabetes Reviews - April 17, 2024 Category: Endocrinology Authors: Aman Khandelwal K Gowthamarajan Jayabalan Nirmal S Ponnusankar Source Type: research
Conceptual Overview of Prevalence of Prediabetes
Curr Diabetes Rev. 2024 Apr 3. doi: 10.2174/0115733998285294240307052909. Online ahead of print.ABSTRACTPrediabetes increases the risk of type 2 diabetes, metabolic syndrome, chronic renal disease, and cardiovascular disease in a person. In current practice, five alternative definitions of prediabetes are utilized, each based on different HbA1C, fasting glucose, and 2-hour glucose cut points. Prediabetes is a common condition that occurs between normal glycemia and diabetes. It is more common in elderly and obese people. The prevalence of prediabetes and diabetes can be influenced by a variety of individual, family, and so...
Source: Current Diabetes Reviews - April 4, 2024 Category: Endocrinology Authors: None Monika Pragi Arora Varun Kumar Pankaj Popli Source Type: research
Conceptual Overview of Prevalence of Prediabetes
Curr Diabetes Rev. 2024 Apr 3. doi: 10.2174/0115733998285294240307052909. Online ahead of print.ABSTRACTPrediabetes increases the risk of type 2 diabetes, metabolic syndrome, chronic renal disease, and cardiovascular disease in a person. In current practice, five alternative definitions of prediabetes are utilized, each based on different HbA1C, fasting glucose, and 2-hour glucose cut points. Prediabetes is a common condition that occurs between normal glycemia and diabetes. It is more common in elderly and obese people. The prevalence of prediabetes and diabetes can be influenced by a variety of individual, family, and so...
Source: Current Diabetes Reviews - April 4, 2024 Category: Endocrinology Authors: None Monika Pragi Arora Varun Kumar Pankaj Popli Source Type: research
Conceptual Overview of Prevalence of Prediabetes
Curr Diabetes Rev. 2024 Apr 3. doi: 10.2174/0115733998285294240307052909. Online ahead of print.ABSTRACTPrediabetes increases the risk of type 2 diabetes, metabolic syndrome, chronic renal disease, and cardiovascular disease in a person. In current practice, five alternative definitions of prediabetes are utilized, each based on different HbA1C, fasting glucose, and 2-hour glucose cut points. Prediabetes is a common condition that occurs between normal glycemia and diabetes. It is more common in elderly and obese people. The prevalence of prediabetes and diabetes can be influenced by a variety of individual, family, and so...
Source: Current Diabetes Reviews - April 4, 2024 Category: Endocrinology Authors: None Monika Pragi Arora Varun Kumar Pankaj Popli Source Type: research
Conceptual Overview of Prevalence of Prediabetes
Curr Diabetes Rev. 2024 Apr 3. doi: 10.2174/0115733998285294240307052909. Online ahead of print.ABSTRACTPrediabetes increases the risk of type 2 diabetes, metabolic syndrome, chronic renal disease, and cardiovascular disease in a person. In current practice, five alternative definitions of prediabetes are utilized, each based on different HbA1C, fasting glucose, and 2-hour glucose cut points. Prediabetes is a common condition that occurs between normal glycemia and diabetes. It is more common in elderly and obese people. The prevalence of prediabetes and diabetes can be influenced by a variety of individual, family, and so...
Source: Current Diabetes Reviews - April 4, 2024 Category: Endocrinology Authors: None Monika Pragi Arora Varun Kumar Pankaj Popli Source Type: research
Conceptual Overview of Prevalence of Prediabetes
Curr Diabetes Rev. 2024 Apr 3. doi: 10.2174/0115733998285294240307052909. Online ahead of print.ABSTRACTPrediabetes increases the risk of type 2 diabetes, metabolic syndrome, chronic renal disease, and cardiovascular disease in a person. In current practice, five alternative definitions of prediabetes are utilized, each based on different HbA1C, fasting glucose, and 2-hour glucose cut points. Prediabetes is a common condition that occurs between normal glycemia and diabetes. It is more common in elderly and obese people. The prevalence of prediabetes and diabetes can be influenced by a variety of individual, family, and so...
Source: Current Diabetes Reviews - April 4, 2024 Category: Endocrinology Authors: None Monika Pragi Arora Varun Kumar Pankaj Popli Source Type: research
Conceptual Overview of Prevalence of Prediabetes
Curr Diabetes Rev. 2024 Apr 3. doi: 10.2174/0115733998285294240307052909. Online ahead of print.ABSTRACTPrediabetes increases the risk of type 2 diabetes, metabolic syndrome, chronic renal disease, and cardiovascular disease in a person. In current practice, five alternative definitions of prediabetes are utilized, each based on different HbA1C, fasting glucose, and 2-hour glucose cut points. Prediabetes is a common condition that occurs between normal glycemia and diabetes. It is more common in elderly and obese people. The prevalence of prediabetes and diabetes can be influenced by a variety of individual, family, and so...
Source: Current Diabetes Reviews - April 4, 2024 Category: Endocrinology Authors: None Monika Pragi Arora Varun Kumar Pankaj Popli Source Type: research
Conceptual Overview of Prevalence of Prediabetes
Curr Diabetes Rev. 2024 Apr 3. doi: 10.2174/0115733998285294240307052909. Online ahead of print.ABSTRACTPrediabetes increases the risk of type 2 diabetes, metabolic syndrome, chronic renal disease, and cardiovascular disease in a person. In current practice, five alternative definitions of prediabetes are utilized, each based on different HbA1C, fasting glucose, and 2-hour glucose cut points. Prediabetes is a common condition that occurs between normal glycemia and diabetes. It is more common in elderly and obese people. The prevalence of prediabetes and diabetes can be influenced by a variety of individual, family, and so...
Source: Current Diabetes Reviews - April 4, 2024 Category: Endocrinology Authors: None Monika Pragi Arora Varun Kumar Pankaj Popli Source Type: research
Conceptual Overview of Prevalence of Prediabetes
Curr Diabetes Rev. 2024 Apr 3. doi: 10.2174/0115733998285294240307052909. Online ahead of print.ABSTRACTPrediabetes increases the risk of type 2 diabetes, metabolic syndrome, chronic renal disease, and cardiovascular disease in a person. In current practice, five alternative definitions of prediabetes are utilized, each based on different HbA1C, fasting glucose, and 2-hour glucose cut points. Prediabetes is a common condition that occurs between normal glycemia and diabetes. It is more common in elderly and obese people. The prevalence of prediabetes and diabetes can be influenced by a variety of individual, family, and so...
Source: Current Diabetes Reviews - April 4, 2024 Category: Endocrinology Authors: None Monika Pragi Arora Varun Kumar Pankaj Popli Source Type: research
Conceptual Overview of Prevalence of Prediabetes
Curr Diabetes Rev. 2024 Apr 3. doi: 10.2174/0115733998285294240307052909. Online ahead of print.ABSTRACTPrediabetes increases the risk of type 2 diabetes, metabolic syndrome, chronic renal disease, and cardiovascular disease in a person. In current practice, five alternative definitions of prediabetes are utilized, each based on different HbA1C, fasting glucose, and 2-hour glucose cut points. Prediabetes is a common condition that occurs between normal glycemia and diabetes. It is more common in elderly and obese people. The prevalence of prediabetes and diabetes can be influenced by a variety of individual, family, and so...
Source: Current Diabetes Reviews - April 4, 2024 Category: Endocrinology Authors: None Monika Pragi Arora Varun Kumar Pankaj Popli Source Type: research
Early Detection of Diabetic Peripheral Neuropathy in Diabetic Patients: A Cross-Sectional Study
CONCLUSION: DNS can be used as a quick and easy initial screening tool implemented in clinical practice for screening DPN. Diabetic patients with DPN tend to have lower NO and increased VEGF; besides, NO levels are also associated with the progression of DPN. Furthermore, education, blood sugar control, and physical exercise, especially leg exercises, can prevent progressive DPN.PMID:38561611 | DOI:10.2174/0115733998297210240325062747 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - April 1, 2024 Category: Endocrinology Authors: Rina Amelia Arlinda Sari Wahyuni Yuki Yunanada Isti Ilmiati Fujiati Juliandi Harahap Hendri Wijaya Zulham Zulham Saktioto Saktioto Source Type: research
Early Detection of Diabetic Peripheral Neuropathy in Diabetic Patients: A Cross-Sectional Study
CONCLUSION: DNS can be used as a quick and easy initial screening tool implemented in clinical practice for screening DPN. Diabetic patients with DPN tend to have lower NO and increased VEGF; besides, NO levels are also associated with the progression of DPN. Furthermore, education, blood sugar control, and physical exercise, especially leg exercises, can prevent progressive DPN.PMID:38561611 | DOI:10.2174/0115733998297210240325062747 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - April 1, 2024 Category: Endocrinology Authors: Rina Amelia Arlinda Sari Wahyuni Yuki Yunanada Isti Ilmiati Fujiati Juliandi Harahap Hendri Wijaya Zulham Zulham Saktioto Saktioto Source Type: research
Early Detection of Diabetic Peripheral Neuropathy in Diabetic Patients: A Cross-Sectional Study
CONCLUSION: DNS can be used as a quick and easy initial screening tool implemented in clinical practice for screening DPN. Diabetic patients with DPN tend to have lower NO and increased VEGF; besides, NO levels are also associated with the progression of DPN. Furthermore, education, blood sugar control, and physical exercise, especially leg exercises, can prevent progressive DPN.PMID:38561611 | DOI:10.2174/0115733998297210240325062747 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - April 1, 2024 Category: Endocrinology Authors: Rina Amelia Arlinda Sari Wahyuni Yuki Yunanada Isti Ilmiati Fujiati Juliandi Harahap Hendri Wijaya Zulham Zulham Saktioto Saktioto Source Type: research
Herbal Nanoformulations for Diabetes: Mechanisms, Formulations, and Clinical Impact
CONCLUSION: Herbal nanoformulations represent a promising avenue for the management of diabetes mellitus, offering improved therapeutic outcomes compared to conventional herbal preparations. Further research is warranted to optimize formulation strategies, elucidate long-term safety profiles, and explore the potential synergistic effects of herbal nanoformulations in combination therapies for diabetes management.PMID:38500279 | DOI:10.2174/0115733998288592240308073925 (Source: Current Diabetes Reviews)
Source: Current Diabetes Reviews - March 19, 2024 Category: Endocrinology Authors: Ms Sunita Rahul Kaushik Krishan Kumar Verma Rehana Parveen Source Type: research
