Multiplex real-time PCR FilmArray performance in the diagnosis of meningoencephalitis: lights and shadows
ConclusionFA was associated with high NPV, but frequent FP results and low PPV, particularly for HSV-1, and especially in patients without high CSF protein levels or pleocytosis. (Source: Infection)
Source: Infection - January 26, 2024 Category: Infectious Diseases Source Type: research
Incongruence between confirmed and suspected clinical cases of Japanese encephalitis virus infection
ConclusionThe results of this study indicate that there is a certain discrepancy between clinically diagnosed and laboratory-confirmed cases of JE. Each reported case should be based on laboratory detection results, which is of great importance in improving the accuracy of case diagnosis and reducing misreporting. Our results are not only important for addressing JE endemic to the Sichuan province, but also provide a valuable reference for the laboratory detection of various notifiable infectious diseases in China and other regions outside China. (Source: Frontiers in cellular and infection microbiology)
Source: Frontiers in cellular and infection microbiology - January 26, 2024 Category: Microbiology Source Type: research
Multiplex real-time PCR FilmArray performance in the diagnosis of meningoencephalitis: lights and shadows
ConclusionFA was associated with high NPV, but frequent FP results and low PPV, particularly for HSV-1, and especially in patients without high CSF protein levels or pleocytosis. (Source: Infection)
Source: Infection - January 25, 2024 Category: Infectious Diseases Source Type: research
Parechovirus A Circulation and Testing Capacities in Europe, 2015-2021
We describe laboratory capacity in Europe for assessing parechovirus circulation, seasonality, and epidemiology. We used retrospective anonymized data collected from parechovirus infection case-patients identified in Europe during January 2015-December 2021. Of 21 laboratories from 18 countries that participated in the study, 16 (76%) laboratories with parechovirus detection capacity reported 1,845 positive samples; 12/16 (75%) with typing capability successfully identified 517 samples. Parechovirus A3 was the most common type (n = 278), followed by A1 (153), A6 (50), A4 (13), A5 (22), and A14 (1). Clinical data from 1,269...
Source: Emerging Infectious Diseases - January 25, 2024 Category: Infectious Diseases Authors: Laura Bubba Eeva K Broberg Thea K Fischer Peter Simmonds Heli Harvala European Non-polio Enterovirus Network working group Source Type: research
Emerging Enterovirus A71 Subgenogroup B5 Causing Severe Hand, Foot, and Mouth Disease, Vietnam, 2023
We report on a 2023 outbreak of severe hand, foot, and mouth disease in southern Vietnam caused by an emerging lineage of enterovirus A71 subgenogroup B5. Affected children were significantly older than those reported during previous outbreaks. The virus should be closely monitored to assess its potential for global dispersal.PMID:38270132 | PMC:PMC10826755 | DOI:10.3201/eid3002.231024 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - January 25, 2024 Category: Infectious Diseases Authors: Nguyen Van Vinh Chau Tang Chi Thuong Nguyen Thanh Hung Nguyen Thi Thu Hong Du Tuan Quy Tran Ba Thien Cao Minh Hiep Ngo Ngoc Quang Minh Truong Huu Khanh Do Duong Kim Han Truong Hoang Chau Truc Nguyen Thi Han Ny Le Kim Thanh Lam Anh Nguyet Cao Thu Thuy Le N Source Type: research
Correction: Molecular epidemiology and phylodynamic analysis of enterovirus 71 in Beijing, China, 2009 –2019
(Source: Virology Journal)
Source: Virology Journal - January 25, 2024 Category: Virology Authors: Jie Li, Zhichao Liang, Da Huo, Yang Yang, Renqing Li, Lei Jia, Xiaoli Wang, Chun Huang and Quanyi Wang Tags: Correction Source Type: research
Viruses, Vol. 16, Pages 170: Molecular Amplification and Cell Culturing Efficiency for Enteroviruses & rsquo; Detection in Cerebrospinal Fluids of Algerian Patients Suffering from Meningitis
Viruses, Vol. 16, Pages 170: Molecular Amplification and Cell Culturing Efficiency for Enteroviruses’ Detection in Cerebrospinal Fluids of Algerian Patients Suffering from Meningitis
Viruses doi: 10.3390/v16020170
Authors:
Abdelwahab Rai
Zohra Ammi
Dahbia Leila Anes-Boulahbal
Aymen Amin Assadi
Abdeltif Amrane
Oussama Baaloudj
Lotfi Mouni
Enteroviruses (EVs) represent a major cause of viral meningitis, being responsible for nearly 1 billion infections each year worldwide. Several techniques were developed to obtain better diagnostic results of EV infections. Herein, we evaluated the efficiency ...
Source: Viruses - January 23, 2024 Category: Virology Authors: Abdelwahab Rai Zohra Ammi Dahbia Leila Anes-Boulahbal Aymen Amin Assadi Abdeltif Amrane Oussama Baaloudj Lotfi Mouni Tags: Article Source Type: research
Emerging Enterovirus A71 Subgenogroup B5 Causing Severe Hand, Foot, and Mouth Disease, Vietnam, 2023
N. Chau et al. (Source: Emerging Infectious Diseases Journal)
Source: Emerging Infectious Diseases Journal - January 18, 2024 Category: Infectious Diseases Source Type: research
Viruses, Vol. 16, Pages 135: Non-Polio Enteroviruses Isolated by Acute Flaccid Paralysis Surveillance Laboratories in the Russian Federation in 1998 & ndash;2021: Distinct Epidemiological Features of Types
Viruses, Vol. 16, Pages 135: Non-Polio Enteroviruses Isolated by Acute Flaccid Paralysis Surveillance Laboratories in the Russian Federation in 1998–2021: Distinct Epidemiological Features of Types
Viruses doi: 10.3390/v16010135
Authors:
Olga E. Ivanova
Tatiana P. Eremeeva
Nadezhda S. Morozova
Yulia M. Mikhailova
Liubov I. Kozlovskaya
Olga Y. Baikova
Armen K. Shakaryan
Alexandr Y. Krasota
Ekaterina A. Korotkova
Elizaveta V. Yakovchuk
Elena Y. Shustova
Alexander N. Lukashev
More than 100 types of non-polio enteroviruses (NPEVs) are ubiquitous in the human population and cause a variet...
Source: Viruses - January 18, 2024 Category: Virology Authors: Olga E. Ivanova Tatiana P. Eremeeva Nadezhda S. Morozova Yulia M. Mikhailova Liubov I. Kozlovskaya Olga Y. Baikova Armen K. Shakaryan Alexandr Y. Krasota Ekaterina A. Korotkova Elizaveta V. Yakovchuk Elena Y. Shustova Alexander N. Lukashev Tags: Article Source Type: research
Detection of enterovirus D68 among children with severe acute respiratory infection in Myanmar
CONCLUSIONS: To our knowledge, this is the first report of EV-D68 detection in children with acute lower respiratory infections in Yangon, Myanmar, in 2017-2018. Detection and detailed virologic analyses of EV-D68 in southeast Asia is an important aspect of worldwide surveillance and will likely be useful in better understanding the worldwide epidemiologic profile of EV-D68 infection.PMID:38233293 | DOI:10.1016/j.jmii.2024.01.001 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - January 17, 2024 Category: Microbiology Authors: Tatsuki Ikuse Yuta Aizawa Ryotaro Kachikawa Kazuhiro Kamata Hidekazu Osada Su Mon Kyaw Win Lasham Di Ja Nay Chi Win Khin Nyo Thein Aye Thida Aye Tun Ai Ito Yadanar Kyaw Htay Htay Tin Yugo Shobugawa Hisami Watanabe Reiko Saito Akihiko Saitoh Source Type: research
Emerging concerns of blood-brain barrier dysfunction caused by neurotropic enteroviral infections
Virology. 2024 Mar;591:109989. doi: 10.1016/j.virol.2024.109989. Epub 2024 Jan 6.ABSTRACTEnteroviruses (EVs), comprise a genus in the Picornaviridae family, which have been shown to be neurotropic and can cause various neurological disorders or long-term neurological condition, placing a huge burden on society and families. The blood-brain barrier (BBB) is a protective barrier that prevents dangerous substances from entering the central nervous system (CNS). Recently, numerous EVs have been demonstrated to have the ability to disrupt BBB, and further lead to severe neurological damage. However, the precise mechanisms of BB...
Source: Virology - January 14, 2024 Category: Virology Authors: Shujie Han Wangquan Ji Guangcai Duan Shuaiyin Chen Haiyan Yang Yuefei Jin Source Type: research
Impact of Respiratory Viruses and SARS-CoV-2 on Febrile Seizures in Saudi Children: Insights into Etiologies, Gender, and Familial Associations
CONCLUSIONS In Saudi children with febrile seizures, distinct viral etiologies, sex, and familial links play pivotal roles. Given regional viral variations, region-tailored diagnostic and therapeutic strategies are paramount. A multicenter prospective cohort study is essential for comprehensive understanding.PMID:38192092 | DOI:10.12659/MSM.942478 (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 9, 2024 Category: Research Authors: Saleh Fahad AlFulayyih Sarah Saleh Al Baridi Sara Amer Alomar Ahmed Nawfal Alshammari Mohammed Shahab Uddin Source Type: research
Impact of Respiratory Viruses and SARS-CoV-2 on Febrile Seizures in Saudi Children: Insights into Etiologies, Gender, and Familial Associations
CONCLUSIONS In Saudi children with febrile seizures, distinct viral etiologies, sex, and familial links play pivotal roles. Given regional viral variations, region-tailored diagnostic and therapeutic strategies are paramount. A multicenter prospective cohort study is essential for comprehensive understanding.PMID:38192092 | PMC:PMC10787381 | DOI:10.12659/MSM.942478 (Source: Medical Science Monitor)
Source: Medical Science Monitor - January 9, 2024 Category: Research Authors: Saleh Fahad AlFulayyih Sarah Saleh Al Baridi Sara Amer Alomar Ahmed Nawfal Alshammari Mohammed Shahab Uddin Source Type: research
Comparison of dye-based and probe-based RT-LAMP in detection of canine astrovirus
In this study, two real-time reverse transcription loop-mediated isothermal amplification (RT-LAMP) assays with high sensitivity, rapidity, and reliability were developed using fluorescence dye and FRET-based assimilating probes for real-time detection of CaAstV. These assays specifically amplified the ORF2 gene of CaAstV and did not amplify any sequences from canine enterovirus. The limit of detection (LOD) of both the probe-based and dye-based RT-LAMPs was 100 copies/ μL. Fluorescence signals were generated within 30 min for the lowest concentration of a standard RNA sample, which was significantly faster than that achi...
Source: Archives of Virology - January 9, 2024 Category: Virology Source Type: research
Pediatric central nervous system infections in the Amazon: clinical and laboratory profiles
CONCLUSION: This study shows the presence of important vaccine-preventable pathogens, and different families of viruses causing CNS infections in the pediatric patients of Manaus.PMID:38186717 | PMC:PMC10768178 | DOI:10.3389/fpubh.2023.1329091 (Source: Herpes)
Source: Herpes - January 8, 2024 Category: Infectious Diseases Authors: Eveny Perlize Melo Marinho Ewerton da Silva Ferreira Caio Cesar Leiva Bastos Barrionuevo Sabrina Ara újo Melo Jady Shayenne Mota Cordeiro Sergio Damasceno Pinto Rossicleia Lins Monte Valderjane Apr ígio da Silva Yasmin Ferreira Martins Monique Freire Re Source Type: research
