CDC Warns Parents To Be On Lookout For Acute Flaccid Myelitis In Children
(CNN) — Parents and pediatricians need to be on the lookout in the coming months for a rare, paralyzing condition that affects young children, the Centers for Disease Control and Prevention said Tuesday. The polio-like condition, called acute flaccid myelitis or AFM, tends to peak every other year, and the last surge of cases was in 2018, when 238 cases were diagnosed across the US, the CDC said. Read: Acute Flaccid Myelitis Fact Sheet This year is likely to see another upsurge but things will be complicated by the coronavirus pandemic. “AFM is a priority for CDC as we prepare for a possible outbreak this ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - August 5, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Featured Health Syndicated CBSN Boston Acute Flaccid Myelitis CNN Source Type: news

AFM, a Biennial Polio-Like Viral Illness, Is Expected to Hit the U.S. in 2020
Nobody foresaw the COVID-19 curveball nature was going to throw at us 2020—which is one of the reasons the world has had so much trouble ducking the pitch. But we’ve know for years that another disease, known as acute flaccid myelitis (AFM), would hit hard this year—beginning this month, in fact. The U.S. Centers for Disease Control and Prevention (CDC) today held a media teleconference and issued a Vital Signs report reminding families that the illness is fast-approaching, and that in a time of pandemic there could be particular challenges in responding to it that would not be present in other years. AF...
Source: TIME: Health - August 4, 2020 Category: Consumer Health News Authors: Jeffrey Kluger Tags: Uncategorized Source Type: news

Coinfection With SARS - CoV - 2, Other Respiratory Pathogens ID ’ d
Rhinovirus/enterovirus, respiratory syncytial virus, non - SARS - CoV - 2 Coronaviridae coinfections detected (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - April 21, 2020 Category: Respiratory Medicine Tags: Family Medicine, Geriatrics, Infections, Internal Medicine, Critical Care, Emergency Medicine, Pathology, Pulmonology, Journal, Source Type: news

Newly emerged enterovirus-A71 C4 isolates may be more virulent than B5 in northern Vietnam
(Kanazawa University) Researchers from Kanazawa University have found a new sublineage of enterovirus A71 (EV-A71) C4 subgenotype with two possible recombinant strains during the 2015-16 outbreak of hand-foot-and-mouth disease in Hanoi, northern Vietnam. Further, they confirmed that the EV-A71-C4 subgenotype may be more virulent than the B5 clinically and experimentally with transgenic mouse model. This has helped elucidate the outbreak and may identify candidate viral strains for developing polyvalent vaccines. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 9, 2020 Category: Infectious Diseases Source Type: news

Neutralizing Antibodies Against Enteroviruses in HFM Disease Neutralizing Antibodies Against Enteroviruses in HFM Disease
A better understanding of neutralizing antibody responses in hand foot and mouth disease could have important implications for vaccine development.Emerging Infectious Diseases (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 19, 2020 Category: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news

Emergency Use Authorizations
Source: U.S. Food and Drug Administration (FDA). Published: 2/4/2020. This resource, updated on February 4, 2020, lists current and terminated Emergency Use Authorizations that make available diagnostic and therapeutic medical devices to diagnose and respond to public health emergencies. The topics covered include 2019 Novel Coronavirus Emergency Use Authorization; Zika Virus Emergency Use Authorization; 2015 Enterovirus D68 (EV-D68) Emergency Use Authorization; 2014 Ebola Virus Emergency Use Authorization; 2013 Coronavirus Emergency Use Authorization (Potential Emergency); 2013 H7N9 Influenza Emergency Use Authorization ...
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - February 4, 2020 Category: International Medicine & Public Health Source Type: news

Enterovirus A71 Outbreak in Children ID'd in Colorado Hospital
WEDNESDAY, Jan. 15, 2020 -- In an observational cohort study recently published in The Lancet Infectious Diseases, details are presented for an outbreak of enterovirus A71 (EV-A71) neurological disease in children who presented to a Colorado... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 15, 2020 Category: Pharmaceuticals Source Type: news

Children's Hospital Colorado uncovers largest US outbreak of neurologic disease to date
(Children's Hospital Colorado) The Lancet Infectious Diseases recently published the results of an observational study conducted by researchers at Children's Hospital Colorado that led to a discovery of the largest outbreak of enterovirus A71 (EV-A71) in the United States. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 8, 2020 Category: International Medicine & Public Health Source Type: news

2019 Research Highlights — Basic Research Insights
Noteworthy NIH advances in basic research include evidence linking enterovirus infections with acute flaccid myelitis, insights into how disrupted sleep may lead to heart disease, and nanoparticle robots that sweep away biofilms. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - December 18, 2019 Category: Consumer Health News Source Type: news

Host cell proteases can process viral capsid proteins
(University of Jyv ä skyl ä - Jyv ä skyl ä n yliopisto) It has long been suggested that a cell protease could take part in enterovirus infection. However, the identity of such proteases have remained unknown. The work performed in the University of Jyv ä skyl ä shows, for the first time, that host cell calpain proteases can process enterovirus polyprotein in vitro. The research was published in Viruses scientific journal in November 2019. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - December 4, 2019 Category: Infectious Diseases Source Type: news

Unexpected viral behavior linked to type 1 diabetes in high-risk children
(University of South Florida (USF Health)) New results from the Environmental Determinants of Diabetes in the Young (TEDDY) study show an association between prolonged enterovirus infection and development of autoimmunity to the insulin-producing pancreatic beta-cells that precedes type 1 diabetes. Conversely, adenovirus C infection seems to confer protection from autoimmunity. The international research suggests new therapeutic avenues for prevention in some children. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - December 2, 2019 Category: Infectious Diseases Source Type: news

Molecular and Clinical Comparison of EV-D68 Outbreaks Molecular and Clinical Comparison of EV-D68 Outbreaks
A new study compares the molecular characteristics and clinical manifestations from two enterovirus D68 outbreak periods. What have we learned?Emerging Infectious Diseases (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - November 27, 2019 Category: Infectious Diseases Tags: Public Health & Prevention Journal Article Source Type: news

Cellular calpain proteases can cleave the enteroviral polyprotein
(University of Jyv ä skyl ä - Jyv ä skyl ä n yliopisto) Enteroviruses can cause severe diseases such as encephalitis or myocarditis, and have been associated with chronic diseases such as type 1 diabetes. In her dissertation at the University of Jyvaskyla M.Sc Mira Laajala focuses on viral and host cell factors that promote the infection of enterovirus B species after cell entry. The research showed that in addition to enteroviral proteases, cellular calpain proteases can cleave the enteroviral polyprotein. The information may possibly be used in antiviral development. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 19, 2019 Category: International Medicine & Public Health Source Type: news

More Evidence that Enterovirus May Cause Kids' Paralyzing Disease
Children with acute flaccid myelitis are more likely to have antibodies against the viral family in their spinal fluid than are children without the illness. (Source: The Scientist)
Source: The Scientist - October 22, 2019 Category: Science Tags: News & Opinion Source Type: news

Enterovirus Implicated in Acute Flaccid Myelitis Enterovirus Implicated in Acute Flaccid Myelitis
Enterovirus is the likely cause of pediatric acute flaccid myelitis, new research suggests. A vaccine against two main suspects could become key in preventing the devastating disorder, experts note.Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - October 22, 2019 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Scientists admit they have no idea how newly discovered enterovirus infects hosts
Researchers at Tokyo University of Agriculture and Technology (TUAT) said we may be facing an 'new system of viral evolution'. The virus doesn't have the same structure as other viruses. (Source: the Mail online | Health)
Source: the Mail online | Health - October 22, 2019 Category: Consumer Health News Source Type: news

Signs of Virus Seen in Disease Paralyzing Kids
The new test detected antibodies for two types of enteroviruses in the spinal fluid of dozens of patients diagnosed with acute flaccid myelitis (AFM), a disease that causes potentially permanent and sometimes life-threatening paralysis in young children. (Source: WebMD Health)
Source: WebMD Health - October 21, 2019 Category: Consumer Health News Source Type: news

Antiviral Antibodies ID'd in CSF of Acute Flaccid Myelitis Cases
MONDAY, Oct. 21, 2019 -- Enterovirus (EV)-specific antibodies have been identified in the cerebrospinal fluid (CSF) of pediatric cases of acute flaccid myelitis (AFM) versus controls, according to a study published online Oct. 21 in Nature... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - October 21, 2019 Category: Pharmaceuticals Source Type: news

'Powerful piece of circumstantial evidence' that virus causes paralyzing illness in kids
Study provides the most robust evidence so far that enteroviruses cause AFM, a mysterious illness that can start like the sniffles but quickly paralyze children. (Source: CBC | Health)
Source: CBC | Health - October 21, 2019 Category: Consumer Health News Tags: News/Health Source Type: news

Scientists discover signs a virus may trigger polio-like illness
Acute flaccid myelitis has left nearly 600 in the US - mostly children - with life-threatening paralysis. At last University of California, San Francisco, scientists found signs it's caused by enteroviruses. (Source: the Mail online | Health)
Source: the Mail online | Health - October 21, 2019 Category: Consumer Health News Source Type: news

What Causes a Mysterious Paralysis in Children? Researchers Find Viral Clues
In one study, nearly 70 percent of children with the disease had antibodies to common enteroviruses that usually produce mild effects but can sometimes cause neurological problems. (Source: NYT Health)
Source: NYT Health - October 21, 2019 Category: Consumer Health News Authors: Pam Belluck Tags: Acute Flaccid Myelitis Enterovirus 68 Paralysis Research Children and Childhood Antibodies Nature Medicine (Journal) Bove, Riley your-feed-science Source Type: news

Scientists Spot Signs of Virus Behind Disease Paralyzing Kids
MONDAY, Oct. 21, 2019 -- A new antibody test appears to have honed in on the most likely cause of a mysterious polio-like disease that regularly sweeps through the United States. The new test detected antibodies for two types of enteroviruses in... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - October 21, 2019 Category: General Medicine Source Type: news

The Toll Mounts From a Mystery Disease Some Call “The New Polio”
Carter Roberts’ motorized wheelchair didn’t arrive until the day he died. It had been a long time coming and his parents had fought hard to get it. The chair cost more than $32,000 and the insurance companies wouldn’t cover it, so the family went to court. One insurer eventually agreed to pay for some components of the chair but not the whole thing. And then none of it mattered anyway. On Sept. 22, 2018, the Roberts’ doorbell rang and the chair was delivered. Also on Sept. 22, 2018, Carter died, just three months shy of his sixth birthday. He had been largely paralyzed for the final two years of his...
Source: TIME: Health - October 9, 2019 Category: Consumer Health News Authors: Jeffrey Kluger Tags: Uncategorized Infectious Disease viruses Source Type: news

Association of Enterovirus D68 With Acute Flaccid Myelitis Association of Enterovirus D68 With Acute Flaccid Myelitis
Findings from a new report further supports the link between enterovirus D68 and AFM among children.Emerging Infectious Diseases (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 9, 2019 Category: Consumer Health News Tags: Neurology & Neurosurgery Journal Article Source Type: news

Disrupting host protein blocks enterovirus infections in mice
Researchers found a host protein that enteroviruses, which cause many cases of the common cold as well as more serious diseases, need to replicate. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - October 1, 2019 Category: Consumer Health News Source Type: news

Enterovirus infection linked to acute flaccid myelitis
Evidence of infection with an enterovirus was found in about 80% of people with the rare but serious condition called acute flaccid myelitis. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - August 26, 2019 Category: Consumer Health News Source Type: news

New Evidence Strengthens Link Between Enterovirus and Acute Flaccid Myelitis New Evidence Strengthens Link Between Enterovirus and Acute Flaccid Myelitis
Patients with acute flaccid myelitis (AFM) commonly have antibodies to enterovirus (EV) peptides in their cerebrospinal fluid (CSF), further supporting a link between EV and AFM, researchers report.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 16, 2019 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

Enterovirus antibodies detected in acute flaccid myelitis patients
NIH-funded study adds to knowledge about rare condition. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - August 13, 2019 Category: American Health Source Type: news

Increase in Enterovirus D68 Infections in Young Children Increase in Enterovirus D68 Infections in Young Children
What accounts for the increased number of reports of EV-D68 infections among infants and young children in the UK?Emerging Infectious Diseases (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 2, 2019 Category: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news

Vital Signs: Surveillance for Acute Flaccid Myelitis --- United States, 2018
Acute flaccid myelitis (AFM) was initially defined as a distinct entity in 2014 following reports of the occurrence of acute limb weakness in previously healthy children across the United States during an outbreak of severe respiratory disease caused by enterovirus D-68 (EV-D68). (Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - July 11, 2019 Category: American Health Tags: MMWR Morbidity & Mortality Weekly Report Public Health Vital Signs Source Type: news

C.D.C. Investigates Rare Paralysis in Children
Cases of acute flaccid myelitis afflicted more than 200 children last year, but much about the illness is still a mystery. (Source: NYT Health)
Source: NYT Health - July 11, 2019 Category: Consumer Health News Authors: Pam Belluck Tags: Acute Flaccid Myelitis Paralysis Centers for Disease Control and Prevention Enterovirus 68 Children and Childhood your-feed-science Source Type: news

C.D.C. Investigates Rare Type of Paralysis in Children
Cases of acute flaccid myelitis afflicted more than 200 children last year, but much about the illness is still a mystery. (Source: NYT Health)
Source: NYT Health - July 10, 2019 Category: Consumer Health News Authors: Pam Belluck Tags: your-feed-science acute flaccid myelitis Paralysis Centers for Disease Control and Prevention Enterovirus 68 Source Type: news

Enterovirus Might be Behind Kids' Paralysis: Preprint
Researchers identify a possible driver of acute flaccid myelitis, a polio-like disease diagnosed in more than 500 children over the last few years. (Source: The Scientist)
Source: The Scientist - June 17, 2019 Category: Science Tags: News & Opinion Source Type: news

What Causes Facial Nerve Palsy?
Discussion Facial nerve palsy has been known for centuries, but in 1821 unilateral facial nerve paralysis was described by Sir Charles Bell. Bell’s palsy (BP) is a unilateral, acute facial paralysis that is clinically diagnosed after other etiologies have been excluded by appropriate history, physical examination and/or laboratory testing or imaging. Symptoms include abnormal movement of facial nerve. It can be associated with changes in facial sensation, hearing, taste or excessive tearing. The right and left sides are equally affected but bilateral BP is rare (0.3%). Paralysis can be complete or incomplete at prese...
Source: PediatricEducation.org - June 3, 2019 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Scientists pinpoint virus which could be the cause of deadly polio-like illness
University of Minnesota experts say enterovirus-D68 could cause acute flaccid myelitis, which struck at least 28 people in the UK last year, like three-year-old Chloe Stevenson (pictured). (Source: the Mail online | Health)
Source: the Mail online | Health - April 19, 2019 Category: Consumer Health News Source Type: news

Acute Flaccid Myelitis Associated With Enterovirus D68 Acute Flaccid Myelitis Associated With Enterovirus D68
Data from a cluster of confirmed cases further supports evidence that enterovirus D68 may be a possible cause of acute flaccid myelitis.Emerging Infectious Diseases (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - April 19, 2019 Category: Allergy & Immunology Tags: Infectious Diseases Journal Article Source Type: news

EV-D68-Associated Acute Respiratory Illness Surveillance EV-D68-Associated Acute Respiratory Illness Surveillance
This report details a preliminary characterization of enterovirus-D68 testing and detection among emergency department and hospitalized patients with acute respiratory illness.Morbidity & Mortality Weekly Report (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 15, 2019 Category: Consumer Health News Tags: Public Health & Prevention Journal Article Source Type: news

A Mysterious, Paralyzing Illness in Kids Is Worrying U.S. Health Officials: New Report
(NEW YORK) — One morning last fall, 4-year-old Joey Wilcox woke up with the left side of his face drooping. It was the first sign of an unfolding nightmare. Three days later, Joey was in a hospital intensive care unit, unable to move his arms or legs or sit up. Spinal taps and other tests failed to find a cause. Doctors worried he was about to lose the ability to breathe. “It’s devastating,” said his father, Jeremy Wilcox, of Herndon, Virginia. “Your healthy child can catch a cold — and then become paralyzed.” Joey, who survived but still suffers some of the effects, was one of 228...
Source: TIME: Health - April 2, 2019 Category: Consumer Health News Authors: MIKE STOBBE / AP Tags: Uncategorized illness medical onetime Source Type: news

CDC: 2017 to 2018 Saw Increase in Enterovirus D68 Detection
FRIDAY, March 29, 2019 -- Based on active surveillance data of acute respiratory illness (ARI), enterovirus D68 (EV-D68) was detected in 0.8 percent of patients in 2017 and in 13.9 percent in 2018, according to research published in the March 29... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 29, 2019 Category: Pharmaceuticals Source Type: news

Big Jump in Enterovirus-D68 Infections
in Multisite Survey (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - March 29, 2019 Category: General Medicine Source Type: news

Big Jump in Enterovirus-D68 Infections in Multisite Survey Big Jump in Enterovirus-D68 Infections in Multisite Survey
The CDC reports a significant rise in enterovirus-D68 (EV-D68) infections in children at seven sites across the US; more surveillance is required to understand trends in EV-D68 infection.Medscape Medical News (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - March 28, 2019 Category: Intensive Care Tags: Infectious Diseases News Source Type: news

Enterovirus D68--Associated Acute Respiratory Illness --- United States, July--October, 2017 and 2018
In the fall of 2014, an outbreak of enterovirus D68 (EV-D68)-associated acute respiratory illness (ARI) occurred in the United States; before 2014, EV-D68 was rarely reported to CDC. (Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - March 28, 2019 Category: American Health Tags: MMWR Morbidity & Mortality Weekly Report Enterovirus D68 Source Type: news

Gut viruses may increase diabetes risk
Research, published inScientific Reports, suggests that high levels of intestinal enteroviruses may increase type-1 diabetes risk in children.Science Daily (Source: Society for Endocrinology)
Source: Society for Endocrinology - February 22, 2019 Category: Endocrinology Source Type: news

Viruses that linger in the gut could trigger type 1 diabetes
(Columbia University's Mailman School of Public Health) Researchers at the Center for Infection and Immunity (CII) at the Columbia University Mailman School of Public Health and the University of New South Wales, Sydney, Australia, provide new evidence supporting an association between elevated levels of enteroviruses in the intestinal tracts of children and islet autoimmunity, a precursor to type 1 diabetes. The paper appears in the journal Scientific Reports. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 20, 2019 Category: International Medicine & Public Health Source Type: news

Child Enterovirus Infection May Up Risk for Developing Celiac Disease
THURSDAY, Feb. 14, 2019 -- A higher frequency of enterovirus infections in early childhood is associated with an increased risk for developing celiac disease, according to a study published online Feb. 13 in the The BMJ. Christian R. Kahrs, M.D.,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 14, 2019 Category: Pharmaceuticals Source Type: news

Enterovirus associated with risk of coeliac disease
Early childhood infection with enterovirus – but not adenovirus – linked to later coeliac disease Related items fromOnMedica Probiotics in newborns might lower diabetes risk Women less likely than men to achieve CHD targets Send children with suspected diabetes to hospital immediately, GPs urged Scans show severe brain damage in Zika-affected babies Many overweight teens don ’t realise they’re too heavy (Source: OnMedica Latest News)
Source: OnMedica Latest News - February 14, 2019 Category: UK Health Source Type: news

Coeliac disease may be caused by a tummy bug in childhood, study claims
Experts now believe it is triggered by enterovirus, which strikes in childhood. They say this discovery could pave the way for a vaccine which could protect against coeliac disease. (Source: the Mail online | Health)
Source: the Mail online | Health - February 14, 2019 Category: Consumer Health News Source Type: news

Outbreak of paralyzing disease linked to non-polio enterovirus through TGen-led study
(The Translational Genomics Research Institute) Using multiple genomic sequencing tests, TGen identified a specific non-polio enterovirus -- EV-D68 -- among at least four children, according to a study published today in the scientific journal mBio. The finding is significant because AFM cases are continuing to increase and there has been no official recognition that this disease is being caused by EV-D68, which limits the research community's ability to develop preventative measures, such as new vaccines. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - January 22, 2019 Category: Infectious Diseases Source Type: news

Enterovirus D68 Surveillance, St. Louis, Missouri, USA, 2016 Enterovirus D68 Surveillance, St. Louis, Missouri, USA, 2016
How did the overall effects of the 2016 outbreak of enterovirus D68 infection differ from the 2014 outbreak?Emerging Infectious Diseases (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 5, 2018 Category: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news

More U.S. Kids Have Recently Been Diagnosed with a Mysterious Paralyzing Illness
(NEW YORK) — More children have been diagnosed with a mysterious paralyzing illness in recent weeks, and U.S. health officials said Tuesday that they still aren’t sure what’s causing it. This year’s count could surpass the tallies seen in similar outbreaks in 2014 and 2016, officials said. Fortunately, the disease remains rare: This year, there have been 90 cases spread among 27 states, the Centers for Disease Control and Prevention said. It’s not clear what’s causing some children to lose the ability to move their face, neck, back, arms or legs. The symptoms tend to occur about a week a...
Source: TIME: Health - November 13, 2018 Category: Consumer Health News Authors: MIKE STOBBE / AP Tags: Uncategorized onetime public health Source Type: news