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Investigating the virulence of coxsackievirus B6 strains and antiviral treatments in a neonatal murine model
This study should provide insights into the pathogenesis of CVB6 and facilitate further research in the development of vaccines and antivirals against CVBs.PMID:38097049 | DOI:10.1016/j.antiviral.2023.105781 (Source: Antiviral Research)
Source: Antiviral Research - December 14, 2023 Category: Virology Authors: Changjian Fang Wenkun Fu Nanyi Liu Huan Zhao Canyang Zhao Kang Yu Che Liu Zhichao Yin Longfa Xu Ningshao Xia Wei Wang Tong Cheng Source Type: research

Emerging porcine Enterovirus G infections, epidemiological, complete genome sequencing, evolutionary and risk factor analysis in India
Virology. 2023 Oct 16;590:109906. doi: 10.1016/j.virol.2023.109906. Online ahead of print.ABSTRACTThe current study reports the in-depth analysis of the epidemiology, risk factors, and molecular characterization of a complete genome of Enterovirus G (EV-G) isolated from Indian pigs. We analysed several genes of EV-G isolates collected from various provinces in India, using phylogenetic analysis, recombination detection, SimPlot, and selection pressure analyses. Our analysis of 534 porcine faecal samples revealed that 11.61% (62/534) of the samples were positive for EV-G. While the G6 genotype was the most predominant, our ...
Source: Virology - December 14, 2023 Category: Virology Authors: Sudipta Bhat Mohd Ikram Ansari Jobin Jose Kattoor Shubhankar Sircar Parvaiz Sikander Dar Pallavi Deol O R Vinodh Kumar Prasad Thomas Souvik Ghosh Mohamed E El Zowalaty Yashpal Singh Malik Source Type: research

Implementation of a Sensitive Method to Assess High Virus Retention Performance of Low-Pressure Reverse Osmosis Process
This study evaluates two methods for the concentration of adenoviruses, enteroviruses and MS2 bacteriophages at different viral concentrations in large (< 200 L) and very large (> 200 L) volumes. The first method is composed of two ultrafiltration membranes with low-molecular weight cut-offs while the second method primarily relies on adsorption and elution phases using electropositive-charged filters. The recovery rates were assessed for both methods. For the ultrafiltrat ion-based protocol, recovery rates were similar for each virus studied: 80% on average at high virus concentrations (106–107 viruses L−1...
Source: Food and Environmental Virology - December 12, 2023 Category: Virology Source Type: research

Impact of Nested Multiplex Polymerase Chain Reaction Assay in the management of pediatric patients with acute respiratory tract infections: a single center experience
CONCLUSIONS: FilmArray enables to improve etiological diagnosis of ALRI and optimize the antimicrobial use of drugs in critical care pediatric patients. Clinical correlation is essential to interpret multiple pathogens and resistance genes.PMID:38075410 | PMC:PMC10705861 | DOI:10.53854/liim-3104-13 (Source: Infezioni in Medicina)
Source: Infezioni in Medicina - December 11, 2023 Category: Infectious Diseases Authors: Basma Sherif Heba M Hamza Hoda Ezz Elarab Abdelwahab Source Type: research