Why Do Some Viruses Have a Seasonal Cycle?
by Gertrud U. Rey Have you ever wondered why some viruses circulate primarily in the winter and others are more prevalent in the summer? Although we don’t have a clear answer to this question, a combination of factors is likely responsible. Work done in the field of respiratory viruses suggests that these viruses can … Why Do Some Viruses Have a Seasonal Cycle? Read More » (Source: virology blog)
Source: virology blog - August 3, 2023 Category: Virology Authors: Gertrud U. Rey Tags: Basic virology Gertrud Rey absolute humidity airborne transmission direct contact enterovirus indirect contact relative humidity respiratory droplets respiratory viruses seasonality temperature Source Type: blogs
Fight Aging! Newsletter, February 13th 2023
This study investigated whether taller Polish adults live longer than their shorter counterparts. Data on declared height were available from 848,860 individuals who died in the years 2004-2008 in Poland. To allow for the cohort effect, the Z-values were generated. Separately for both sexes, Pearson's r coefficients of correlation were calculated. Subsequently, one way ANOVA was performed.
The correlation between adult height and longevity was negative and statistically significant in both men and women. After eliminating the effects of secular trends in height, the correlation was very weak (r = -0.0044 in men and ...
Source: Fight Aging! - February 12, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Viral Infection in Middle Age Correlates with Later Dementia Risk
A range of evidence suggests that persistent viral infection contributes to the risk of suffering neurodegenerative conditions such as Alzheimer's disease. This may be due to mechanisms relating to amyloid-β accumulation, in its role as an anti-microbial peptide, a part of the innate immune system. It may have more to do with lasting chronic inflammation subsequent to infection. Researchers here note another addition to the epidemiological data on this topic, in this case linking severe infections requiring hospitalization with later dementia risk. The effect sizes here are large and last for a long time following infecti...
Source: Fight Aging! - February 10, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
TWiV 936: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses detection of a highly divergent type 3 vaccine-derived poliovirus in a child with a severe primary immunodeficiency disorder, severe respiratory illnesses associated with rhinoviruses and/or enteroviruses including EV-D68, effects of vaccination and previous infection on Omicron infections in children, COVID-19-associated hospitalizations among vaccinated and unvaccinated adults 18 years or older in 13 US states, effectiveness of COVID-19 vaccines over time prior to Omicron emergence in Ontario, Canada, nasal IgA wanes 9 months after hospitalization with COVID-19 an...
Source: virology blog - September 17, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology antiviral coronavirus COVID-19 delta inflammation influenza Long Covid marburg virus monkeypox monoclonal antibody Omicron pandemic poliovirus SARS-CoV-2 vaccine vaccine booster variant of concern Source Type: blogs
TWiV 930: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses antibody response against nonpoliovirus enteroviruses, clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain, object and surface contamination with monkeypox virus, monkeypox virus infection in humans across 16 countries, clinical characteristics of ambulatory and hospitalized patients with monkeypox virus infection, compassionate use of Tecovirimat […] (Source: virology blog)
Source: virology blog - August 27, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology antiviral coronavirus COVID-19 delta inflammation Long Covid marburg virus monkeypox monoclonal antibody Omicron pandemic poliovirus SARS-CoV-2 vaccine vaccine booster variant of concern viruses Source Type: blogs
TWiV 866: EV antibodies rEVolutionize our thinking
Amy returns to TWiV to discuss her work on the identification of cross-reactive antibody responses among diverse enteroviruses, and the implications for our understanding of viral pathogenesis and seroprevalence studies. (Source: virology blog)
Source: virology blog - February 15, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology antibody cross-reactive antibody enterovirus epitope neutralization plaque assay poliovirus serology Source Type: blogs
TWiV 832: Heavy metal flu fighters
TWiV reviews the vials labeled smallpox that were not, re-emergence of enterovirus D68 in Europe, efficacy of inactivated SARS-CoV-2 vaccine, and cellular correlates of protection for an oral influenza virus vaccine. Click arrow to playDownload TWiV 832 (77 MB .mp3, 128 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Show notes at microbe.tv/twiv (Source: virology blog)
Source: virology blog - November 21, 2021 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology adenovirus vector adjuvant correlate of protection Covaxin COVID-19 inactivated vaccine influenza influenza oral vaccine mass cytometry pandemic SARS-CoV-2 smallpox vaccine efficacy vaccinia virus viral Source Type: blogs
21st century outbreaks
Which diseases have generated the highest number of cases from outbreaks during the first two decades of the 21st century? In this blog, we can use GIDEON’s data to find out.
‘Disease outbreak’ is a scary term for many, but every year we suffer dozens, if not hundreds, of localized and international disease outbreaks across the world. While these outbreaks are always significant to those affected, they rarely generate headlines, and can sometimes go unnoticed outside of the Healthcare Industry.
An “outbreak” is often defined as an increase in case numbers for a particular disease in a defined place and...
Source: GIDEON blog - December 3, 2020 Category: Databases & Libraries Authors: Kristina Symes Tags: Epidemiology News Outbreaks Source Type: blogs
Top 10 most prominent diseases of the 21st Century
Which diseases have generated the highest number of cases from outbreaks during the first two decades of the 21st century? In this blog, we can use GIDEON’s data to find out.
‘Disease outbreak’ is a scary term for many, but every year we suffer dozens, if not hundreds, of localized and international disease outbreaks across the world. While these outbreaks are always significant to those affected, they rarely generate headlines, and can sometimes go unnoticed outside of the Healthcare Industry.
An “outbreak” is often defined as an increase in case numbers for a particular disease in a defined place and time. ...
Source: GIDEON blog - December 1, 2020 Category: Databases & Libraries Authors: Kristina Symes Tags: Epidemiology News Outbreaks Source Type: blogs
Teenager with chest pain and slightly elevated troponin. What happens then?
This is a previously healthy male teenager who was awoken by chest pain. He was seen at another hospital and found to have a slightly elevated troponin, then underwent a CT pulmonary angiogram (PE) protocol which revealed a right sided pneumonia. He was treated with Ceftriaxone and azithromycin.p.p1 {margin: 0.0px 0.0px 0.0px 0.0px; font: 12.0px Calibri; background-color: #fefefe}The pain is described as located in the midsternal area, radiating to the right arm, described as 8-9/10 and worse with deep inspirations. He endorsed cough, fever, and body aches in the previous day...
Source: Dr. Smith's ECG Blog - December 9, 2019 Category: Cardiology Authors: Steve Smith Source Type: blogs
TWiV 572: Your EV-D68th nervous breakdown
Amy joins the TWiV team to review evidence that enterovirus D68 is an etiologic agent of childhood paralysis, and her finding that the ability of the virus to infect cells of the nervous system is not a recently acquired property. Click arrow to play Download TWiV 572 (73 MB .mp3, 121 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become […] (Source: virology blog)
Source: virology blog - November 3, 2019 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology acute flaccid myelitis AFM astrocytes cerebrospinal fluid CSF enterovirus D68 neurons neurotropic poliovirus serology viral viruses Source Type: blogs
Neurotropism of enterovirus D68 is not a recently acquired property
With Amy Rosenfeld Enterovirus D68 (EV-D68) was first isolated from children with respiratory disease in 1962. No outbreaks of infection were detected until the late summer and early fall of 2014, and then in 2016 and 2018. During these epidemics of respiratory disease, some children developed polio-like paralysis. We have recently published a paper showing […] (Source: virology blog)
Source: virology blog - October 24, 2019 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Information acute flaccid myelitis astrocyte childhood paralysis enterovirus D68 neuron neurotropism poliovirus viral viruses Source Type: blogs
TWiV 568: Karolinska viral
In the second episode from the Karolinska Institute in Stockholm, Vincent speaks with Jan Albert, Petter Brodin, and Anna Smed-Sörensen about their work on enterovirus D68, systems immunology, and human pulmonary viral infection and inflammation. Click arrow to play Download TWiV 568 (58 MB .mp3, 95 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv (Source: virology blog)
Source: virology blog - October 6, 2019 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology acute flaccid myelitis dendritic cell enterovirus D68 epidemiology hantavirus influenza virus maternal antibodies mononuclear phagocyte newborn anti-viral antibodies placenta respiratory viral infection system Source Type: blogs
Enterovirus D68 and childhood paralysis
The Centers for Disease Control and Prevention thinks that viruses play a role in the childhood paralysis called acute flaccid myelitis (AFM). The finding of antibodies to enterovirus D68 (EV-D68) in the cerebrospinal fluid of patients with AFM strengthens the link between infection with this virus and AFM. Acute flaccid myelitis (AFM), which mainly occurs […] (Source: virology blog)
Source: virology blog - August 15, 2019 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Information AFM antibodies childhood paralysis CSF enterovirus EV-D68 viral viruses Source Type: blogs
Enteroviruses review
Excerpt from a book review of Enteroviruses: Omics, Molecular Biology, and Control "The depth of the coverage on the most recent enterovirus research makes this an asset to anyone interested in the diverse group of viruses" from SIMB News read more ...Enteroviruses: Omics, Molecular Biology, and Control Edited by: William T. Jackson and Carolyn B. Coyne"frontiers in the study of the 12 species of the genus" (ProtoView); "the current most important enterovirus research" (Biotechnol. Agron. Soc. Environ.) read more ... (Source: Microbiology Blog: The weblog for microbiologists.)
Source: Microbiology Blog: The weblog for microbiologists. - March 26, 2019 Category: Microbiology Source Type: blogs
