Functional features of a novel interferon-stimulated gene SHFL: a comprehensive review
Front Microbiol. 2023 Dec 11;14:1323231. doi: 10.3389/fmicb.2023.1323231. eCollection 2023.ABSTRACTVarious interferon (IFN)-stimulated genes (ISGs), expressed via Janus kinase-signal transducer and activator of transcription (JAK-STAT) signaling pathway-stimulated IFNs to increase antiviral effects or regulate immune response, perform different roles in virus-infected cells. In recent years, a novel ISG, SHFL, which is located in the genomic region 19p13.2 and comprises two isoforms, has been studied as a virus-inhibiting agent. Studies have shown that SHFL suppressive effects on human immunodeficiency virus-1 (HIV), Zika ...
Source: Herpes - December 27, 2023 Category: Infectious Diseases Authors: Xingzheng Wang A-Mei Zhang Source Type: research
Respiratory Viruses in Wastewater Compared with Clinical Samples, Leuven, Belgium
Emerg Infect Dis. 2024 Jan;30(1):141-145. doi: 10.3201/eid3001.231011.ABSTRACTIn a 2-year study in Leuven, Belgium, we investigated the use of wastewater sampling to assess community spread of respiratory viruses. Comparison with the number of positive clinical samples demonstrated that wastewater data reflected circulation levels of typical seasonal respiratory viruses, such as influenza, respiratory syncytial virus, and enterovirus D68.PMID:38147067 | DOI:10.3201/eid3001.231011 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - December 26, 2023 Category: Infectious Diseases Authors: Annabel Rector Mandy Bloemen Marijn Thijssen Bram Pussig Kurt Beuselinck Marc Van Ranst Elke Wollants Source Type: research
Respiratory Viruses in Wastewater Compared with Clinical Samples, Leuven, Belgium
Emerg Infect Dis. 2024 Jan;30(1):141-145. doi: 10.3201/eid3001.231011.ABSTRACTIn a 2-year study in Leuven, Belgium, we investigated the use of wastewater sampling to assess community spread of respiratory viruses. Comparison with the number of positive clinical samples demonstrated that wastewater data reflected circulation levels of typical seasonal respiratory viruses, such as influenza, respiratory syncytial virus, and enterovirus D68.PMID:38147067 | DOI:10.3201/eid3001.231011 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - December 26, 2023 Category: Infectious Diseases Authors: Annabel Rector Mandy Bloemen Marijn Thijssen Bram Pussig Kurt Beuselinck Marc Van Ranst Elke Wollants Source Type: research
Respiratory Viruses in Wastewater Compared with Clinical Samples, Leuven, Belgium
Emerg Infect Dis. 2024 Jan;30(1):141-145. doi: 10.3201/eid3001.231011.ABSTRACTIn a 2-year study in Leuven, Belgium, we investigated the use of wastewater sampling to assess community spread of respiratory viruses. Comparison with the number of positive clinical samples demonstrated that wastewater data reflected circulation levels of typical seasonal respiratory viruses, such as influenza, respiratory syncytial virus, and enterovirus D68.PMID:38147067 | DOI:10.3201/eid3001.231011 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - December 26, 2023 Category: Infectious Diseases Authors: Annabel Rector Mandy Bloemen Marijn Thijssen Bram Pussig Kurt Beuselinck Marc Van Ranst Elke Wollants Source Type: research
Respiratory Viruses in Wastewater Compared with Clinical Samples, Leuven, Belgium
Emerg Infect Dis. 2024 Jan;30(1):141-145. doi: 10.3201/eid3001.231011.ABSTRACTIn a 2-year study in Leuven, Belgium, we investigated the use of wastewater sampling to assess community spread of respiratory viruses. Comparison with the number of positive clinical samples demonstrated that wastewater data reflected circulation levels of typical seasonal respiratory viruses, such as influenza, respiratory syncytial virus, and enterovirus D68.PMID:38147067 | DOI:10.3201/eid3001.231011 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - December 26, 2023 Category: Infectious Diseases Authors: Annabel Rector Mandy Bloemen Marijn Thijssen Bram Pussig Kurt Beuselinck Marc Van Ranst Elke Wollants Source Type: research
Respiratory Viruses in Wastewater Compared with Clinical Samples, Leuven, Belgium
Emerg Infect Dis. 2024 Jan;30(1):141-145. doi: 10.3201/eid3001.231011.ABSTRACTIn a 2-year study in Leuven, Belgium, we investigated the use of wastewater sampling to assess community spread of respiratory viruses. Comparison with the number of positive clinical samples demonstrated that wastewater data reflected circulation levels of typical seasonal respiratory viruses, such as influenza, respiratory syncytial virus, and enterovirus D68.PMID:38147067 | PMC:PMC10756384 | DOI:10.3201/eid3001.231011 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - December 26, 2023 Category: Infectious Diseases Authors: Annabel Rector Mandy Bloemen Marijn Thijssen Bram Pussig Kurt Beuselinck Marc Van Ranst Elke Wollants Source Type: research
Respiratory Viruses in Wastewater Compared with Clinical Samples, Leuven, Belgium
Emerg Infect Dis. 2024 Jan;30(1):141-145. doi: 10.3201/eid3001.231011.ABSTRACTIn a 2-year study in Leuven, Belgium, we investigated the use of wastewater sampling to assess community spread of respiratory viruses. Comparison with the number of positive clinical samples demonstrated that wastewater data reflected circulation levels of typical seasonal respiratory viruses, such as influenza, respiratory syncytial virus, and enterovirus D68.PMID:38147067 | PMC:PMC10756384 | DOI:10.3201/eid3001.231011 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - December 26, 2023 Category: Infectious Diseases Authors: Annabel Rector Mandy Bloemen Marijn Thijssen Bram Pussig Kurt Beuselinck Marc Van Ranst Elke Wollants Source Type: research
Respiratory Viruses in Wastewater Compared with Clinical Samples, Leuven, Belgium
Emerg Infect Dis. 2024 Jan;30(1):141-145. doi: 10.3201/eid3001.231011.ABSTRACTIn a 2-year study in Leuven, Belgium, we investigated the use of wastewater sampling to assess community spread of respiratory viruses. Comparison with the number of positive clinical samples demonstrated that wastewater data reflected circulation levels of typical seasonal respiratory viruses, such as influenza, respiratory syncytial virus, and enterovirus D68.PMID:38147067 | PMC:PMC10756384 | DOI:10.3201/eid3001.231011 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - December 26, 2023 Category: Infectious Diseases Authors: Annabel Rector Mandy Bloemen Marijn Thijssen Bram Pussig Kurt Beuselinck Marc Van Ranst Elke Wollants Source Type: research
Viruses, Vol. 16, Pages 40: Use of Capsid Integrity-qPCR for Detecting Viral Capsid Integrity in Wastewater
In conclusion, this study demonstrates the utility of PMAxx dyes to evaluate capsid integrity across a diverse range of viruses commonly monitored in wastewater. (Source: Viruses)
Source: Viruses - December 26, 2023 Category: Virology Authors: Jessica L. Kevill Kata Farkas Nicola Ridding Nicholas Woodhall Shelagh K. Malham Davey L. Jones Tags: Article Source Type: research
A novel VP1-based enzyme-linked immunosorbent assay revealed widespread Enterovirus G infections in Guangxi, China
In this study, we developed a novel serological detection method based on the structural protein, VP1 of EV-G. The intra-assay and inter-assay coefficient variations were 3.2~8.9% and 2.6~8.0%, respectively. There was no cross-reaction of the VP1-based enzyme-linked immunosorbent assay (ELISA) with antisera against the other known porcine viruses. In addition, a comparison was made with other methods including the developed indirect ELISAs based on VP2 and VP3 proteins and western blot (WB) analysis, which demonstrated the reliability of the novel method. Using the VP1-based ELISA, we carried out the first seroepidemiologi...
Source: Journal of Virological Methods - December 24, 2023 Category: Virology Authors: Dalin Hong Jinni Bian Lingyou Zeng Shiting Huang Yifeng Qin Ying Chen Zuzhang Wei Weijian Huang Kang Ouyang Source Type: research
A novel VP1-based enzyme-linked immunosorbent assay revealed widespread Enterovirus G infections in Guangxi, China
In this study, we developed a novel serological detection method based on the structural protein, VP1 of EV-G. The intra-assay and inter-assay coefficient variations were 3.2~8.9% and 2.6~8.0%, respectively. There was no cross-reaction of the VP1-based enzyme-linked immunosorbent assay (ELISA) with antisera against the other known porcine viruses. In addition, a comparison was made with other methods including the developed indirect ELISAs based on VP2 and VP3 proteins and western blot (WB) analysis, which demonstrated the reliability of the novel method. Using the VP1-based ELISA, we carried out the first seroepidemiologi...
Source: Journal of Virological Methods - December 24, 2023 Category: Virology Authors: Dalin Hong Jinni Bian Lingyou Zeng Shiting Huang Yifeng Qin Ying Chen Zuzhang Wei Weijian Huang Kang Ouyang Source Type: research
A novel VP1-based enzyme-linked immunosorbent assay revealed widespread Enterovirus G infections in Guangxi, China
In this study, we developed a novel serological detection method based on the structural protein, VP1 of EV-G. The intra-assay and inter-assay coefficient variations were 3.2~8.9% and 2.6~8.0%, respectively. There was no cross-reaction of the VP1-based enzyme-linked immunosorbent assay (ELISA) with antisera against the other known porcine viruses. In addition, a comparison was made with other methods including the developed indirect ELISAs based on VP2 and VP3 proteins and western blot (WB) analysis, which demonstrated the reliability of the novel method. Using the VP1-based ELISA, we carried out the first seroepidemiologi...
Source: Journal of Virological Methods - December 24, 2023 Category: Virology Authors: Dalin Hong Jinni Bian Lingyou Zeng Shiting Huang Yifeng Qin Ying Chen Zuzhang Wei Weijian Huang Kang Ouyang Source Type: research
A novel VP1-based enzyme-linked immunosorbent assay revealed widespread Enterovirus G infections in Guangxi, China
In this study, we developed a novel serological detection method based on the structural protein, VP1 of EV-G. The intra-assay and inter-assay coefficient variations were 3.2~8.9% and 2.6~8.0%, respectively. There was no cross-reaction of the VP1-based enzyme-linked immunosorbent assay (ELISA) with antisera against the other known porcine viruses. In addition, a comparison was made with other methods including the developed indirect ELISAs based on VP2 and VP3 proteins and western blot (WB) analysis, which demonstrated the reliability of the novel method. Using the VP1-based ELISA, we carried out the first seroepidemiologi...
Source: Journal of Virological Methods - December 24, 2023 Category: Virology Authors: Dalin Hong Jinni Bian Lingyou Zeng Shiting Huang Yifeng Qin Ying Chen Zuzhang Wei Weijian Huang Kang Ouyang Source Type: research
Enterovirus E infects bovine peripheral blood mononuclear cells. Implications for pathogenesis?
CONCLUSION: Interactions of EV-E with bovine immune cells may indicate potential evasion mechanisms of the virus. There is also a risk that an infection with this virus can predispose the organism to secondary infections, especially bacterial ones.PMID:38130447 | PMC:PMC10730555 | DOI:10.2478/jvetres-2023-0061 (Source: Cell Research)
Source: Cell Research - December 22, 2023 Category: Cytology Authors: Joanna Ma łaczewska Ma łgorzata Wróbel Edyta Kaczorek- Łukowska Wojciech R ękawek Source Type: research
Asymptomatic viruses detectable in saliva in the first year of life: a narrative review
Pediatr Res. 2023 Dec 22. doi: 10.1038/s41390-023-02952-0. Online ahead of print.ABSTRACTViral infections are common in children. Many can be asymptomatic or have delayed health consequences. In view of increasing availability of point-of-care viral detection technologies, with possible application in newborn screening, this review aimed to (1) identify potentially asymptomatic viruses detectable in infants under one year old, via saliva/nasopharyngeal swab, and (2) describe associations between viruses and long-term health conditions. We systematically searched Embase(Ovid), Medline(Ovid) and PubMed, then further searched...
Source: Pediatric Research - December 22, 2023 Category: Pediatrics Authors: Melody Goh Charissa Joy Alanna N Gillespie Qi Rui Soh Fan He Valerie Sung Source Type: research
