d-mannose-sensitive pilus of Acinetobacter baumannii is linked to biofilm formation and adherence onto respiratory tract epithelial cells
CONCLUSION: This is the first study confirming that Csu pilus of A. baumannii belongs to mannose-sensitive type 1 pilus family and contributes to biofilm formation and bacterial adherence to human epithelial cells.PMID:33610507 | DOI:10.1016/j.jmii.2021.01.008 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - February 21, 2021 Category: Microbiology Authors: Chyi-Liang Chen Anna Dudek Yi-Hua Liang Rajendra Prasad Janapatla Hao-Yuan Lee Long Hsu Han-Yueh Kuo Cheng-Hsun Chiu Source Type: research

Cancer as an infectious disease: A different treatment alternative using a combination of tigecycline and pyrvinium pamoate - An example of breast cancer
CONCLUSION: Combining low dose of tigecycline use with pyrvinium pamoate is a novel approach for breast cancer treatment. Appropriate combined therapy in breast cancer is recommended to improve outcomes. Other problems like drug resistance occur in patients or the microbes surrounding breast tissues would confer susceptibility to cancers then influence the effectiveness of treatment, which could be improved through combined therapy.PMID:33610508 | DOI:10.1016/j.jmii.2020.12.008 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - February 21, 2021 Category: Microbiology Authors: Shu-Wei Huang Ming-Tsung Sun Wen-Sen Lee Ying-Shih Su Yi-Tzu Lee Ming-Hsien Chiang Yung-Chih Wang Ya-Sung Yang Shian-Chiuan Tzeng Yu-Min Huang Feng-Huei Lin Source Type: research

Species identification and antifungal susceptibility of uncommon blood yeast isolates
CONCLUSIONS: For uncommon Candida species, the unmet need for current databases of two commercial MALDI-TOF MS systems is highlighted, and the oligonucleotide array may serve as a supplement.PMID:33610509 | DOI:10.1016/j.jmii.2021.01.009 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - February 21, 2021 Category: Microbiology Authors: Ming-Chi Li Hung-Jen Tang Chi-Jung Wu Shin-Wei Wang Shu-Li Su Wei-Lun Liu Wen-Chien Ko Yee-Chun Chen Source Type: research

Clinical and visual outcomes following endogenous endophthalmitis: 175 consecutive cases from a tertiary referral center in Taiwan
CONCLUSION: Our study demonstrated that liver abscess is the most common source of endogenous endophthalmitis in Taiwan. The visual outcome is good when the presenting visual acuity is relatively well preserved and when the infecting organism is fungus. The use of intra-vitreal antibiotics reduces the risk of enucleation.PMID:33610510 | DOI:10.1016/j.jmii.2021.01.010 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - February 21, 2021 Category: Microbiology Authors: George Kuo Chieh-Li Yen Yueh-An Lu Chao-Yu Chen Ming-Hui Sun YuJr Lin Ya-Chung Tian Hsiang-Hao Hsu Source Type: research

Younger adults with mild-to-moderate COVID-19 exhibited more prevalent olfactory dysfunction in Taiwan
CONCLUSION: This study demonstrated that young adults were prone to develop olfactory dysfunctions. In the flu season, olfactory dysfunction is considered a specific screening criterion for early detecting COVID-19 in the community. TWSIT can serve as a decent test for quantifying and qualifying olfactory dysfunction.PMID:33610511 | PMC:PMC7869675 | DOI:10.1016/j.jmii.2021.01.006 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - February 21, 2021 Category: Microbiology Authors: Meng-Yu Cheng Wen-Hsin Hsih Mao-Wang Ho Yi-Chyi Lai Wei-Chih Liao Chih-Yu Chen Tsung-Chia Chen Yu-Lin Lee Po-Yu Liu Chih-Chuan Kao Chia-Huei Chou Po-Chang Lin Chih-Yu Chi Lih-Ying Leong Chih-Jaan Tai Min-Chi Lu Source Type: research

d-mannose-sensitive pilus of Acinetobacter baumannii is linked to biofilm formation and adherence onto respiratory tract epithelial cells
CONCLUSION: This is the first study confirming that Csu pilus of A. baumannii belongs to mannose-sensitive type 1 pilus family and contributes to biofilm formation and bacterial adherence to human epithelial cells.PMID:33610507 | DOI:10.1016/j.jmii.2021.01.008 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - February 21, 2021 Category: Microbiology Authors: Chyi-Liang Chen Anna Dudek Yi-Hua Liang Rajendra Prasad Janapatla Hao-Yuan Lee Long Hsu Han-Yueh Kuo Cheng-Hsun Chiu Source Type: research

Cancer as an infectious disease: A different treatment alternative using a combination of tigecycline and pyrvinium pamoate - An example of breast cancer
CONCLUSION: Combining low dose of tigecycline use with pyrvinium pamoate is a novel approach for breast cancer treatment. Appropriate combined therapy in breast cancer is recommended to improve outcomes. Other problems like drug resistance occur in patients or the microbes surrounding breast tissues would confer susceptibility to cancers then influence the effectiveness of treatment, which could be improved through combined therapy.PMID:33610508 | DOI:10.1016/j.jmii.2020.12.008 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - February 21, 2021 Category: Microbiology Authors: Shu-Wei Huang Ming-Tsung Sun Wen-Sen Lee Ying-Shih Su Yi-Tzu Lee Ming-Hsien Chiang Yung-Chih Wang Ya-Sung Yang Shian-Chiuan Tzeng Yu-Min Huang Feng-Huei Lin Source Type: research

Species identification and antifungal susceptibility of uncommon blood yeast isolates
CONCLUSIONS: For uncommon Candida species, the unmet need for current databases of two commercial MALDI-TOF MS systems is highlighted, and the oligonucleotide array may serve as a supplement.PMID:33610509 | DOI:10.1016/j.jmii.2021.01.009 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - February 21, 2021 Category: Microbiology Authors: Ming-Chi Li Hung-Jen Tang Chi-Jung Wu Shin-Wei Wang Shu-Li Su Wei-Lun Liu Wen-Chien Ko Yee-Chun Chen Source Type: research

Clinical and visual outcomes following endogenous endophthalmitis: 175 consecutive cases from a tertiary referral center in Taiwan
CONCLUSION: Our study demonstrated that liver abscess is the most common source of endogenous endophthalmitis in Taiwan. The visual outcome is good when the presenting visual acuity is relatively well preserved and when the infecting organism is fungus. The use of intra-vitreal antibiotics reduces the risk of enucleation.PMID:33610510 | DOI:10.1016/j.jmii.2021.01.010 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - February 21, 2021 Category: Microbiology Authors: George Kuo Chieh-Li Yen Yueh-An Lu Chao-Yu Chen Ming-Hui Sun YuJr Lin Ya-Chung Tian Hsiang-Hao Hsu Source Type: research

Younger adults with mild-to-moderate COVID-19 exhibited more prevalent olfactory dysfunction in Taiwan
CONCLUSION: This study demonstrated that young adults were prone to develop olfactory dysfunctions. In the flu season, olfactory dysfunction is considered a specific screening criterion for early detecting COVID-19 in the community. TWSIT can serve as a decent test for quantifying and qualifying olfactory dysfunction.PMID:33610511 | PMC:PMC7869675 | DOI:10.1016/j.jmii.2021.01.006 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - February 21, 2021 Category: Microbiology Authors: Meng-Yu Cheng Wen-Hsin Hsih Mao-Wang Ho Yi-Chyi Lai Wei-Chih Liao Chih-Yu Chen Tsung-Chia Chen Yu-Lin Lee Po-Yu Liu Chih-Chuan Kao Chia-Huei Chou Po-Chang Lin Chih-Yu Chi Lih-Ying Leong Chih-Jaan Tai Min-Chi Lu Source Type: research

Failure of pre-exposure prophylaxis with on-demand tenofovir disoproxil fumarate/emtricitabine resulting in emergence of antiretroviral resistance
J Microbiol Immunol Infect. 2021 Feb 6:S1684-1182(21)00025-6. doi: 10.1016/j.jmii.2021.01.011. Online ahead of print.NO ABSTRACTPMID:33597075 | DOI:10.1016/j.jmii.2021.01.011 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - February 18, 2021 Category: Microbiology Authors: Yu-Yu Hsiao Yi-Chia Huang Sui-Yuan Chang Ching-Hua Kuo Shu-Fang Chang Ya-Ting Lin Yu-Zhen Luo Yu-Lin Lee Chien-Ching Hung Source Type: research

The dynamic change of antibody index against Covid-19 is a powerful diagnostic tool for the early phase of the infection and salvage PCR assay errors
CONCLUSION: This antibody testing has a wide dynamic ranges of COI and, thus, could be utilized in the early infection phase. This may also compliment and even help to avoid possible PCR errors. Therefore, this can serve as a powerful diagnostic tool, needed in the frontline of the clinic and hospitals.PMID:33593710 | PMC:PMC7784537 | DOI:10.1016/j.jmii.2020.12.009 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - February 17, 2021 Category: Microbiology Authors: Masao Omata Yosuke Hirotsu Hiroki Sugiura Makoto Maejima Yuki Nagakubo Kenji Amemiya Miyoko Hayakawa Toshiharu Tsutsui Yumiko Kakizaki Hitoshi Mochizuki Yoshihiro Miyashita Source Type: research

Clinical validation of an automated reverse transcription-insulated isothermal PCR assay for the detection of severe acute respiratory syndrome coronavirus 2
J Microbiol Immunol Infect. 2021 Feb 1:S1684-1182(21)00019-0. doi: 10.1016/j.jmii.2021.01.005. Online ahead of print.ABSTRACTTo determine clinical performance of the single-target SARS-CoV-2 orf 1 ab reverse transcription-insulated isothermal PCR (RT-iiPCR) assay, the positive percentage agreement between this assay and a laboratory real-time RT-PCR assay was 96.8% (30 of 31; 95% confidence interval [CI], 90.5%-100%) and the negative percentage agreement was 97.1% (67 of 69; 95% CI, 93.1%-100%).PMID:33582073 | PMC:PMC7849545 | DOI:10.1016/j.jmii.2021.01.005 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - February 14, 2021 Category: Microbiology Authors: Pai-Ling Chang Chia-Yi Lin Cheng-Pin Chen Yi-Chun Lin Hui-Chun Hu Shu-Hsing Cheng Chien-Yu Cheng Source Type: research

Molecular characterization of Clostridioides difficile ribotype 027 in a major Chinese hospital
CONCLUSIONS: In Our study, five C. difficile 027 isolates were identified and characterized using MLST, PCR ribotyping and whole genome sequencing. We proposed that C. difficile 027 infections are probably neglected in China. Further epidemiological studies across the country together with the introduction of routine diagnostic testing and multi-center or national level surveillance are needed to ascertain the size of this potentially significant problem.PMID:33563561 | DOI:10.1016/j.jmii.2021.01.003 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - February 10, 2021 Category: Microbiology Authors: Ren-Feng Zhang Yu-Xia Man Yuan-Yuan Bai Chun-Hong Shao Chun-Mei Liu Cong-Hui Wang Yong-Xing Lei Yong Wang Yan Jin Source Type: research

Does early bloodstream infection pose a significant risk of in-hospital mortality in adults with burns?
CONCLUSIONS: BSI and burns ≥30% TBSA were significant risk factors of mortality. Early detection of BSI-14 is critical in burn care as its probability of mortality can be as high as 40% in patients ≥30% TBSA of burns. To reduce the risk of mortality, early in ventilator withdrawal, invasive lines and tubes removal, and early grafting should be emphasized besides infection control and appropriate use of antibiotics.PMID:33563562 | DOI:10.1016/j.jmii.2021.01.004 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - February 10, 2021 Category: Microbiology Authors: Eng-Kean Yeong Wang-Huei Sheng Source Type: research

d-mannose-sensitive pilus of Acinetobacter baumannii is linked to biofilm formation and adherence onto respiratory tract epithelial cells.
CONCLUSION: This is the first study confirming that Csu pilus of A. baumannii belongs to mannose-sensitive type 1 pilus family and contributes to biofilm formation and bacterial adherence to human epithelial cells. PMID: 33610507 [PubMed - as supplied by publisher] (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - February 10, 2021 Category: Microbiology Authors: Chen CL, Dudek A, Liang YH, Janapatla RP, Lee HY, Hsu L, Kuo HY, Chiu CH Tags: J Microbiol Immunol Infect Source Type: research

Species identification and antifungal susceptibility of uncommon blood yeast isolates.
CONCLUSIONS: For uncommon Candida species, the unmet need for current databases of two commercial MALDI-TOF MS systems is highlighted, and the oligonucleotide array may serve as a supplement. PMID: 33610509 [PubMed - as supplied by publisher] (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - February 10, 2021 Category: Microbiology Authors: Li MC, Tang HJ, Wu CJ, Wang SW, Su SL, Liu WL, Ko WC, Chen YC Tags: J Microbiol Immunol Infect Source Type: research

Clinical and visual outcomes following endogenous endophthalmitis: 175 consecutive cases from a tertiary referral center in Taiwan.
CONCLUSION: Our study demonstrated that liver abscess is the most common source of endogenous endophthalmitis in Taiwan. The visual outcome is good when the presenting visual acuity is relatively well preserved and when the infecting organism is fungus. The use of intra-vitreal antibiotics reduces the risk of enucleation. PMID: 33610510 [PubMed - as supplied by publisher] (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - February 10, 2021 Category: Microbiology Authors: Kuo G, Yen CL, Lu YA, Chen CY, Sun MH, Lin Y, Tian YC, Hsu HH Tags: J Microbiol Immunol Infect Source Type: research

Younger adults with mild-to-moderate COVID-19 exhibited more prevalent olfactory dysfunction in Taiwan.
CONCLUSION: This study demonstrated that young adults were prone to develop olfactory dysfunctions. In the flu season, olfactory dysfunction is considered a specific screening criterion for early detecting COVID-19 in the community. TWSIT can serve as a decent test for quantifying and qualifying olfactory dysfunction. PMID: 33610511 [PubMed - as supplied by publisher] (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - February 8, 2021 Category: Microbiology Authors: Cheng MY, Hsih WH, Ho MW, Lai YC, Liao WC, Chen CY, Chen TC, Lee YL, Liu PY, Kao CC, Chou CH, Lin PC, Chi CY, Leong LY, Tai CJ, Lu MC Tags: J Microbiol Immunol Infect Source Type: research

Failure of pre-exposure prophylaxis with on-demand tenofovir disoproxil fumarate/emtricitabine resulting in emergence of antiretroviral resistance.
PMID: 33597075 [PubMed - as supplied by publisher] (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - February 6, 2021 Category: Microbiology Authors: Hsiao YY, Huang YC, Chang SY, Kuo CH, Chang SF, Lin YT, Luo YZ, Lee YL, Hung CC Tags: J Microbiol Immunol Infect Source Type: research

Molecular characterization of Clostridioides difficile ribotype 027 in a major Chinese hospital.
CONCLUSIONS: In Our study, five C. difficile 027 isolates were identified and characterized using MLST, PCR ribotyping and whole genome sequencing. We proposed that C. difficile 027 infections are probably neglected in China. Further epidemiological studies across the country together with the introduction of routine diagnostic testing and multi-center or national level surveillance are needed to ascertain the size of this potentially significant problem. PMID: 33563561 [PubMed - as supplied by publisher] (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - January 28, 2021 Category: Microbiology Authors: Zhang RF, Man YX, Bai YY, Shao CH, Liu CM, Wang CH, Lei YX, Wang Y, Jin Y Tags: J Microbiol Immunol Infect Source Type: research

Proven invasive pulmonary aspergillosis in the early clinical course of severe fever with thrombocytopenia syndrome: Importance of an early diagnosis.
PMID: 33549478 [PubMed - as supplied by publisher] (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - January 28, 2021 Category: Microbiology Authors: Seong GM, Yoo JR, Kim JG, Hyun CL, Kim M, Oh HJ, Lee KH Tags: J Microbiol Immunol Infect Source Type: research

Epidemiology of norovirus gastroenteritis in hospitalized children under five years old in western China, 2015-2019.
Abstract OBJECTIVES: Norovirus is associated with one-fifth of all gastroenteritis cases, but basic epidemiological data is lacking, especially in developing countries. As long-term surveillance on norovirus gastroenteritis is scarce in western China, this study aims to update the epidemiological knowledge of norovirus gastroenteritis and to characterize the genotypes of norovirus strains. METHODS: Stool samples were collected from hospitalized children under 5 years old with gastroenteritis in Chengdu, China. All samples were tested for norovirus as well as rotavirus, sapovirus, enteric adenovirus, and astro...
Source: Journal of Microbiology, Immunology, and Infection - January 26, 2021 Category: Microbiology Authors: Cao RR, Ma XZ, Li WY, Wang BN, Yang Y, Wang HR, Kuang Y, You JZ, Zhao ZY, Ren M, Zhou LL, Li MY Tags: J Microbiol Immunol Infect Source Type: research

cgMLST@Taiwan: A web service platform for Vibrio cholerae cgMLST profiling and global strain tracking.
Abstract BACKGROUND: Cholera, a rapidly dehydrating diarrheal disease caused by toxigenic Vibrio cholerae, is a leading cause of morbidity and mortality in some regions of the world. Core genome multilocus sequence typing (cgMLST) is a promising approach in generating genetic fingerprints from whole-genome sequencing (WGS) data for strain comparison among laboratories. METHODS: We constructed a V. cholerae core gene allele database using an in-house developed computational pipeline, a database with cgMLST profiles converted from genomic sequences from the National Center for Biotechnology Information, and bui...
Source: Journal of Microbiology, Immunology, and Infection - January 15, 2021 Category: Microbiology Authors: Chen YS, Tu YH, Chen BH, Liu YY, Hong YP, Teng RH, Wang YW, Chiou CS Tags: J Microbiol Immunol Infect Source Type: research

Eosinopenia < 100/ μL as a marker of active COVID-19: An observational prospective study.
Eosinopenia
Source: Journal of Microbiology, Immunology, and Infection - January 8, 2021 Category: Microbiology Authors: Outh R, Boutin C, Gueudet P, Suzuki M, Saada M, Aumaître H Tags: J Microbiol Immunol Infect Source Type: research

Huge brain abscess caused by Actinomyces israelii associated with chronic sinusitis: A rare case report.
PMID: 33454221 [PubMed - as supplied by publisher] (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - January 7, 2021 Category: Microbiology Authors: Chou LH, Su YS, Chen FL, Lee WS, Li WH Tags: J Microbiol Immunol Infect Source Type: research

A rare patient with primary endogenous Aspergillus endophthalmitis.
PMID: 33454222 [PubMed - as supplied by publisher] (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - January 6, 2021 Category: Microbiology Authors: Chiu YY, Chen YH, Hsiao HH, Du JS Tags: J Microbiol Immunol Infect Source Type: research

An outbreak of Ralstonia pickettii bloodstream infection among pediatric leukemia patients.
CONCLUSIONS: We reported an outbreak of R. pickettii BSIs in highly immunocompromised patients due to contaminated intravascular solution, which was rapidly controlled by infection control measures. Vigilant surveillance by hospital infection control teams and prompt investigation to identify the source of nosocomial infections are crucial to stop an outbreak. PMID: 33461864 [PubMed - as supplied by publisher] (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - January 6, 2021 Category: Microbiology Authors: Bedir Demirdag T, Ozkaya-Parlakay A, Bayrakdar F, Gulhan B, Kanik Yuksek S, Suzuk Yildiz S, Mumcuoglu İ, Dinc B, Yarali N Tags: J Microbiol Immunol Infect Source Type: research

Secondary syphilis with alopecia and ocular manifestation.
PMID: 33423955 [PubMed - as supplied by publisher] (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - January 5, 2021 Category: Microbiology Authors: Chang KM, Nadi L, Wallach F Tags: J Microbiol Immunol Infect Source Type: research

Clinical characteristics of bacteremia caused by Haemophilus and Aggregatibacter species and antimicrobial susceptibilities of the isolates.
CONCLUSIONS: The overall hospital mortality of 28.1% was observed among patients with bacteremia due to Haemophilus and Aggregatibacter species. A higher SOFA score was and independent predictor of poor 7-day clinical outcomes in patients with community-acquired H. influenzae bacteremia. PMID: 33390332 [PubMed - as supplied by publisher] (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - December 31, 2020 Category: Microbiology Authors: Chien YC, Huang YT, Liao CH, Chien JY, Hsueh PR Tags: J Microbiol Immunol Infect Source Type: research

Seroepidemiology of the human herpesvirus 8 infection among people living with HIV in Taiwan, 2014-2018.
Abstract BACKGROUND: Human herpesvirus type 8 (HHV-8) can be transmitted through unprotected sex as HIV. We aimed to investigate the seroincidence of HHV-8 and associated factors among people living with HIV (PLWH). METHODS: From 2014 to 2018, blood samples of PLWH on the first date of HIV care were determined for antibodies against HHV-8. Individuals testing HHV-8-seronegative at baseline were followed for at least four months to estimate the annual seroconversion rate. To identify the factors associated with HHV-8 seroconversion, we compared the clinical characteristics between seroconverters and non-seroco...
Source: Journal of Microbiology, Immunology, and Infection - December 9, 2020 Category: Microbiology Authors: Tsai MJ, Sun HY, Hsieh SM, Sheng WH, Chuang YC, Huang YS, Huang SH, Su LH, Su YC, Liu WC, Chang SY, Hung CC Tags: J Microbiol Immunol Infect Source Type: research

Inhibition of the clinical isolates of Acinetobacter baumannii by Pseudomonas aeruginosa: In  vitro assessment of a case-based study.
CONCLUSION: Selected strains of PA exert inhibitory actions on MDR-AB with PCN being a possible inhibitory agent. This finding raises the possibility of developing effective therapeutic antibiotics and disinfectant from specific components of PA for the treatment and control of Acinetobacter-associated infections in hospital settings. PMID: 33341362 [PubMed - as supplied by publisher] (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - December 9, 2020 Category: Microbiology Authors: Huang CW, Lin YS, Huang WC, Lai CC, Chien HJ, Hu NJ, Chen JH Tags: J Microbiol Immunol Infect Source Type: research

Hepatitis C outbreak in a respiratory care ward associated with frequent injections: Taiwan, 2017.
CONCLUSION: HCV infection was associated with frequent injections and infection control lapses. Healthcare workers should follow safe injection practices and reduce injection frequency to prevent HCV transmission. PMID: 33342703 [PubMed - as supplied by publisher] (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - December 9, 2020 Category: Microbiology Authors: Wu PY, Hung MN, Huang WL, Yang JY, Su CP Tags: J Microbiol Immunol Infect Source Type: research

To what degree could clinical trials in evidence based medicine reflect reality in the treatment of candidemia?
CONCLUSION: Only 24% of candidemia patients were eligible for the clinical trials. Thus, we can see that clinical trials might not correctly reflect the real world among candidemia patients. PMID: 33339744 [PubMed - as supplied by publisher] (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - December 2, 2020 Category: Microbiology Authors: Asai N, Sakanashi D, Suematsu H, Kato H, Hagihara M, Shiota A, Koizumi Y, Yamagishi Y, Mikamo H Tags: J Microbiol Immunol Infect Source Type: research

Need for a high-specificity test for confirming weakly positive result in an immunochromatographic SARS-CoV-2-specific antigen test: A case report.
PMID: 33309009 [PubMed - as supplied by publisher] (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - December 1, 2020 Category: Microbiology Authors: Tanimoto T, Matsumura M, Tada S, Fujita S, Ueno S, Hamai K, Omoto T, Maeda H, Nishisaka T, Ishikawa N Tags: J Microbiol Immunol Infect Source Type: research

A mysterious surge of aspergillosis among non-SARS-CoV-2 patients during COVID-19 pandemic.
PMID: 33309227 [PubMed - as supplied by publisher] (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - December 1, 2020 Category: Microbiology Authors: Lai CC, Chen CM, Liao KM, Chao CM, Chan KS, Yu WL Tags: J Microbiol Immunol Infect Source Type: research

Mandatory mask-wearing policy and universal anti-viral treatment mitigate influenza outbreaks during the COVID-19 pandemic.
PMID: 33214081 [PubMed - as supplied by publisher] (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - November 7, 2020 Category: Microbiology Authors: Wu HJ, Ko NY, Lin WL, Ko WC, Lee NY, Chen PL Tags: J Microbiol Immunol Infect Source Type: research

Laboratory diagnosis of COVID-19 in China: A  review of challenging cases and analysis.
Laboratory diagnosis of COVID-19 in China: A review of challenging cases and analysis. J Microbiol Immunol Infect. 2020 Oct 17;: Authors: Jing R, Kudinha T, Zhou ML, Xiao M, Wang H, Yang WH, Xu YC, Hsueh PR Abstract Since the initial emergence of coronavirus disease 2019 (COVID-19) in Wuhan, Hubei province, China, a rapid spread of the disease occurred around the world, rising to become an international global health concern at pandemic level. In the face of this medical challenge threatening humans, the development of rapid and accurate methods for early screening and diagnosis of COVID-19 becam...
Source: Journal of Microbiology, Immunology, and Infection - October 17, 2020 Category: Microbiology Authors: Jing R, Kudinha T, Zhou ML, Xiao M, Wang H, Yang WH, Xu YC, Hsueh PR Tags: J Microbiol Immunol Infect Source Type: research

Differentiation of qacA and qacB using high-resolution melt curve analysis, and both qacA and qacB but not qacC or norA types increase chlorhexidine minimal inhibitory concentrations in Staphylococcus aureus isolates.
Abstract BACKGROUND: Chlorhexidine is one of the most essential ingredients in infection control applications. Except qacA, the effects of other various efflux-medicated biocide genes (including qacB, qacC, qacEΔ1, qacH or norA) on biguanides resistance are still controversial. In addition, most of the studies have discussed the effect of qacA/B on clinical S. aureus isolates but not that qacA or qacB individually. METHODS: In total, 254 methicillin-resistant Staphylococcus aureus (MRSA), selected 30 methicillin-susceptible S. aureus (MSSA) clinical isolates from different patients during 2014-2015 and ...
Source: Journal of Microbiology, Immunology, and Infection - October 10, 2020 Category: Microbiology Authors: Lin KH, Lin CY, Huang CC, Ho YL, Yang SF, Ho CM Tags: J Microbiol Immunol Infect Source Type: research

Initial SARS-CoV-2 PCR crossing point does not predict hospitalization and duration of PCR positivity.
This study aimed to determine if the crossing point of the initial positive SARS-CoV-2 PCR test correlated with patient demographics, subsequent hospitalization, or duration of positivity. Seventy-three patients with two or more positive PCR tests had a median time of 23 days to two consecutive negative results. PMID: 33069621 [PubMed - as supplied by publisher] (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - October 10, 2020 Category: Microbiology Authors: Eberly AR, Challener DW, Shweta FNU, Fida M, Boerger AC, Assi M, O'Horo JC, Binnicker MJ Tags: J Microbiol Immunol Infect Source Type: research

Triple therapy with hydroxychloroquine, azithromycin, and ciclesonide for COVID-19 pneumonia.
We report the effectiveness and adverse effects of triple therapy with hydroxychloroquine, azithromycin, and ciclesonide in patients with COVID-19 pneumonia. The clinical condition of the patients improved within 5 days in response to the therapy. PMID: 33054978 [PubMed - as supplied by publisher] (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - October 5, 2020 Category: Microbiology Authors: Mori N, Katayama M, Nukaga S Tags: J Microbiol Immunol Infect Source Type: research

Unique surface structures of community-associated methicillin-resistant Staphylococcus aureus ST8/SCCmecIVl.
Abstract Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) threatens human health. A local CA-MRSA with ST8/SCCmecIVl (CA-MRSA/J) has emerged in Japan, being associated with progression from bullous impetigo to potentially fatal invasive infection. We found that CA-MRSA/J has unique bacterial surface structures, spikes, spikes with a cap, and long spikes, reflecting clinical origins. PMID: 33060039 [PubMed - as supplied by publisher] (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - October 5, 2020 Category: Microbiology Authors: Wan TW, Teng LJ, Yamamoto T Tags: J Microbiol Immunol Infect Source Type: research

Remdesivir use in the coronavirus disease 2019 pandemic: A mini-review.
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative viral pathogen of coronavirus disease 2019 (COVID-19), appears to have various clinical presentations and may result in severe respiratory failure. The global SARS-CoV-2-associated viral pneumonia pandemic was first reported in December 2019 in China. Based on known pharmacological mechanisms, many therapeutic drugs have been repurposed to target SARS-CoV-2. Among these drugs, remdesivir appears to be the currently most promising according to several clinical trials and reports of compassionate use. In this mini-review, we summari...
Source: Journal of Microbiology, Immunology, and Infection - October 5, 2020 Category: Microbiology Authors: Yang CJ, Wei YJ, Chang HL, Chang PY, Tsai CC, Chen YH, Hsueh PR Tags: J Microbiol Immunol Infect Source Type: research

International air traffic and COVID-19 geographical incidence in Brazil.
PMID: 33060040 [PubMed - as supplied by publisher] (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - October 3, 2020 Category: Microbiology Authors: Alves JG, Ferreira Lima TP Tags: J Microbiol Immunol Infect Source Type: research

Antibody response to SARS-CoV-2 in people living with HIV.
PMID: 33046418 [PubMed - as supplied by publisher] (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - October 2, 2020 Category: Microbiology Authors: Yamamoto S, Saito M, Nagai E, Toriuchi K, Nagai H, Yotsuyanagi H, Nakagama Y, Kido Y, Adachi E Tags: J Microbiol Immunol Infect Source Type: research

COVID-19 associated with pulmonary aspergillosis: A literature review.
Abstract Bacterial or virus co-infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported in many studies, however, the knowledge on Aspergillus co-infection among patients with coronavirus disease 2019 (COVID-19) was limited. This literature review aims to explore and describe the updated information about COVID-19 associated with pulmonary aspergillosis. We found that Aspergillus spp. can cause co-infections in patients with COVID-19, especially in severe/critical illness. The incidence of IPA in COVID-19 ranged from 19.6% to 33.3%. Acute respiratory distress syndrome requiri...
Source: Journal of Microbiology, Immunology, and Infection - September 23, 2020 Category: Microbiology Authors: Lai CC, Yu WL Tags: J Microbiol Immunol Infect Source Type: research

Emergence of macrolide-resistant Streptococcus pyogenes emm12 in southern Taiwan from 2000 to 2019.
Abstract BACKGROUND: Group A Streptococcus (GAS) is an important pathogen causing morbidity and mortality worldwide. Surveillance of resistance and emm type has important implication to provide helpful information on the changing GAS epidemiology and empirical treatment. METHODS: To study the emergence of resistant GAS in children with upper respiratory tract infection (URTI), a retrospective study was conducted from 2000 to 2019 in southern Taiwan. Microbiological studies, including antibiotic susceptibility, were performed. GAS emm types and sequences were determined by molecular methods. The population was...
Source: Journal of Microbiology, Immunology, and Infection - September 11, 2020 Category: Microbiology Authors: Tsai WC, Shen CF, Lin YL, Shen FC, Tsai PJ, Wang SY, Lin YS, Wu JJ, Chi CY, Liu CC Tags: J Microbiol Immunol Infect Source Type: research

Efficacy of clarithromycin-naproxen-oseltamivir combination therapy versus oseltamivir alone in hospitalized pediatric influenza patients.
CONCLUSION: The clarithromycin-naproxen-oseltamivir combination group experienced a more rapid defervescence and a more rapid decline of influenza virus titer than the group treated with oseltamivir alone. Further consideration should be given to whether the overall benefits of combination therapy in hospitalized pediatric influenza patients outweigh the risks. PMID: 32978076 [PubMed - as supplied by publisher] (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - September 11, 2020 Category: Microbiology Authors: Lee CW, Tai YL, Huang LM, Chi H, Huang FY, Chiu NC, Huang CY, Tu YH, Wang JY, Huang DT Tags: J Microbiol Immunol Infect Source Type: research

In  vitro activity of arbekacin against multidrug-resistant gram-negative bacilli.
CONCLUSIONS: Arbekacin showed similar MIC50 values to amikacin and gentamicin, a lower MIC50 value than tobramycin, and a higher MIC50 value than plazomicin. PMID: 32962921 [PubMed - as supplied by publisher] (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - September 8, 2020 Category: Microbiology Authors: Albano M, Fleischmann WA, Greenwood-Quaintance KE, Patel R Tags: J Microbiol Immunol Infect Source Type: research

SARS-CoV-2-induced immunodysregulation and the need for higher clinical suspicion for co-infection and secondary infection in COVID-19 patients.
Abstract Cases of co-infection and secondary infection emerging during the current Coronavirus Disease-19 (COVID-19) pandemic are a major public health concern. Such cases may result from immunodysregulation induced by the SARS-CoV-2 virus. Pandemic preparedness must include identification of disease natural history and common secondary infections to implement clinical solutions. PMID: 32943328 [PubMed - as supplied by publisher] (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - September 7, 2020 Category: Microbiology Authors: Parrill A, Tsao T, Dong V, Huy NT Tags: J Microbiol Immunol Infect Source Type: research