Investigation of a nosocomial outbreak of fungemia caused by Candida pelliculosa (Pichia anomala) in a Korean tertiary care center
Conclusions This is the first report of a nosocomial outbreak involving 11 patients in 2 ICUs and 2 general wards caused by C. pelliculosa in South Korea. Infection control measures are important for decreasing transmission of C. pelliculosa in the hospital. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - June 28, 2017 Category: Microbiology Source Type: research

The different modes of binding of the dust mite allergens, Der f 7 and Der p 7, on a monoclonal antibody WH9 contribute to the differential reactivity
Conclusion The structure models of Der f 7-WH9 and Der p 7-WH9 complexes revealed that the differential modes of binding of Der p 7 and Der f 7 allergens on WH9 contribute to the differential reactivity of WH9 against the Der f 7 and the Der p 7 mite allergens. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - June 28, 2017 Category: Microbiology Source Type: research

In vitro activity of aminoglycosides, clofazimine, D-cycloserine and dapsone against 83 Mycobacterium avium complex clinical isolates
Conclusion When treating MAC diseases, species identification plays an important role in choosing treatment regimens. Combination of isepamicin and clofazimine may be a promising regimen in M. intracellulare-associated disease. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - June 28, 2017 Category: Microbiology Source Type: research

A “Ct contrast”-based strain-specific real-time quantitative PCR system for Lactobacilllus paracasei subsp. paracasei NTU 101
Conclusion The two-component, “Ct contrast” approach is useful for qPCR discrimination when no ideal PCR target is available or the variance of the target site is unpredictable. The Ct contrast approach might provide a simple and robust solution for other challenging qPCR targets. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - June 28, 2017 Category: Microbiology Source Type: research

Epidemiology, clinical features, and microbiology of patients with diarrhea in community clinics in Taiwan
Conclusion In Taiwan, viruses were the predominant pathogens among patients with diarrheal diseases who visited community clinics. The therapeutic strategies for diarrheal patients should be based on the epidemiological and clinical characteristics. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - June 28, 2017 Category: Microbiology Source Type: research

High levels of soluble GPR56/ADGRG1 are associated with positive rheumatoid factor and elevated tumor necrosis factor in patients with rheumatoid arthritis
Conclusion we conclude that sGPR56 is present in vivo and sGPR56 level is elevated in certain chronic inflammatory diseases such as RA. Hence, sGPR56 might be considered a potential biomarker for RA disease progression. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - June 28, 2017 Category: Microbiology Source Type: research

Risk factors and outcomes of cerebrospinal fluid overdrainage in HIV-negative patients with cryptococcal meningitis after the ventriculoperitoneal shunting procedure
Conclusions CSF overdrainage after the VP shunt procedure is not rare, especially in patients with a high-risk of cryptococcal meningitis who also have a prolonged duration of hydrocephalus and/or IICP. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - June 28, 2017 Category: Microbiology Source Type: research

The plasmid-mediated fosfomycin resistance determinants and synergy of fosfomycin and meropenem in carbapenem-resistant Klebsiella pneumoniae isolates in Taiwan
Conclusions A clone (pulsotype XXIII, ST11) has been found to be prevailing among fosfomycin-resistant CRKP in Taiwan. According to the in vitro data, the combination of fosfomycin and meropenem is a potentially alternative choice. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - June 28, 2017 Category: Microbiology Source Type: research

Risk factors for hospital acquisition of trimethoprim-sulfamethoxazole resistant Stenotrophomonas maltophilia in adults: a matched case-control study
Conclusion Previous fluoroquinolone use was an independent risk factor for hospital-acquired TSRSM occurrence in adult inpatients, suggesting that judicious administration of fluoroquinolone may be important for limiting TSRSM occurrence. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - June 28, 2017 Category: Microbiology Source Type: research

Systemic Lupus Erythematosus and Thyroid Disease – Experience in a single Medical Center in Taiwan
Conclusion SLE patients had significantly higher rate of hyperthyroidism, hypothyroidism, and AITD than the matched control. Among lupus patients, the risks of thyroid diseases are even higher in the presence overlap syndrome. SLE patients with thyroid diseases had higher risk of renal and CNS involvement. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - June 28, 2017 Category: Microbiology Source Type: research

Antimicrobial peptides as potential anti-biofilm agents against multi-drug resistant bacteria
Publication date: Available online 26 June 2017 Source:Journal of Microbiology, Immunology and Infection Author(s): Pooi Yin Chung, Ramona Khanum Bacterial resistance to commonly used drugs has become a global health problem, causing increased infection cases and mortality rate. One of the main virulence determinants in many bacterial infections is biofilm formation, which significantly increases bacterial resistance to antibiotics and innate host defence. In the search to address the chronic infections caused by biofilms, antimicrobial peptides (AMP) have been considered as potential alternative agents to conventional an...
Source: Journal of Microbiology, Immunology and Infection - June 27, 2017 Category: Microbiology Source Type: research

Invasive Pneumococcal Disease Caused by Ceftriaxone-Resistant Streptococcus pneumoniae in Taiwan
Conclusions The increase of ceftriaxone resistance in pneumococci in part driven by PCV7 vaccination in Taiwan is worrisome. The use of PCV13 in children as well as in the elderly population is likely to offer protection from the infection caused by ceftriaxone-resistant pneumococci. It is important to giving an effective drug such as penicillin, fluoroquinolones or vancomycin in 2 days for improving outcome of IPD patients. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - June 27, 2017 Category: Microbiology Source Type: research

Clinical Outcomes and Prognostic Factors of Patients with Severe Influenza Receiving Intravenous Peramivir Salvage Therapy in Intensive Care Units
Conclusion As a salvage therapy, intravenous peramivir provided a survival rate of 62% and was well tolerated in patients with severe influenza. The initiation of effective antiviral treatment as early as possible within 48 hours is recommended for hospitalized patients. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - June 27, 2017 Category: Microbiology Source Type: research

Nasal Staphylococcus aureus and methicillin-resistant Staphylococcus aureus carriage among college student athletes in northern Taiwan
Publication date: Available online 26 June 2017 Source:Journal of Microbiology, Immunology and Infection Author(s): Hong-Kai Wang, Chun-Yen Huang, Chih-Jung Chen, Yhu-Chering Huang Of 259 college students in northern Taiwan surveyed, nasal carriage rate of Staphylococcus aureus and methicillin-resistant S. aureus (MRSA) was 22.4% and 1.54%, respectively and no significant difference was found between athlete students and non-athlete students. Three of four MRSA isolates belonged to sequence type 59, the endemic community clone. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - June 27, 2017 Category: Microbiology Source Type: research

Safety and efficacy of anti-influenza drugs, intravenous peramivir against influenza virus infection in elderly patients with underlying disease
Publication date: Available online 26 June 2017 Source:Journal of Microbiology, Immunology and Infection Author(s): Kazufumi Takamatsu, Satoshi Marumo, Motonari Fukui, Atsuko Hata We retrospectively analyzed data of 38 elderly patients, each with an underlying disease, to evaluate peramivir safety and efficacy. Six patients (15.8%) experienced adverse events, all tolerated. Median time from administration until the return to normal temperatures was 31.5 hr (95% CI: 22.4–40.6). Results confirm intravenous peramivir’s usefulness. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - June 27, 2017 Category: Microbiology Source Type: research

Implementation of a national bundle care program to reduce catheter-associated urinary tract infection in high-risk units of hospitals in Taiwan
Conclusions The implementation of CA-UTI bundle care successfully reduced CA-UTI in Taiwanese high-risk units. A process surveillance checklist can be helpful for understanding which parts of the bundle care require improvements. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - June 27, 2017 Category: Microbiology Source Type: research

Inactivated Orf-Virus Shows Disease Modifying Antiviral Activity in a Guinea Pig Model of Genital Herpesvirus Infection
Conclusion iORFV effectively suppressed recurrences in guinea pigs experimentally infected with HSV. iORFV did not only reduce recurrent disease episodes but was, compared with ACV, more effective in reducing latency as measured by viral DNA detected in dorsal root ganglia of infected animals. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - June 27, 2017 Category: Microbiology Source Type: research

Zoonotic potential of Helicobacter spp.
Publication date: Available online 20 June 2017 Source:Journal of Microbiology, Immunology and Infection Author(s): Irena Mladenova-Hristova, Olga Grekova, Ami Patel The genus Helicobacter contains more than 35 species. Helicobacter pylori is the most important in terms of human health. Discovery of these helicobacters gives opportunity to understand the relationship between these bacteria which colonise the animal and human gut and their effect on the host. Infection with Helicobacter spp. and the associated diseases in their hosts allow us to study the pathogenic mechanisms. The potential zoonotic pathway for the transm...
Source: Journal of Microbiology, Immunology and Infection - June 25, 2017 Category: Microbiology Source Type: research

Procalcitonin as a diagnostic biomarker for septic shock and bloodstream infection in burn patients from the Formosa Fun Coast dust explosion
Conclusions PCT levels can be helpful in determining the septic shock and bloodstream infection in burn patients but CRP levels, PLT, and WBC count were of little diagnostic value. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - June 23, 2017 Category: Microbiology Source Type: research

Streptococcus sanguis bacteremia complicating endocarditis associated with colonic adenocarcinoma
Publication date: Available online 23 June 2017 Source:Journal of Microbiology, Immunology and Infection Author(s): Fu-Lun Chen, Shio-Shin Jean, Tsong-Yih Ou, Giueng-Chueng Wang, Fang-Lan Yu, Wen-Sen Lee Streptococcus bovis bacteremia is well known to be associated with colorectal tumor. But most physicians are unaware of the association between Streptococcus sanguis bacteremia and colorectal malignancy. In this case report, we highlight this association and discuss a case of Streptococcus sanguis bacteremia complicating endocarditis associated with a late stage invasive colonic adenocarcinoma (Source: Journal of Microbio...
Source: Journal of Microbiology, Immunology and Infection - June 23, 2017 Category: Microbiology Source Type: research

Risk factors and outcomes for the acquisition of carbapenem-resistant Gram-negative bacillus bacteremia: a retrospective propensity-matched case control study
Conclusion Risk factors for acquisition of CR GNB bacteremia identified in this study each may serve as a reminder alerting clinicians to hospitalized patients at risk for CR GNB bacteremia requiring appropriate antibiotic coverage, and in these circumstances, combined antibiotics may be used until antimicrobial de-escalation/adjustment is clearly indicated by the subsequently identified pathogenic GNB and its susceptibility profile. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - June 23, 2017 Category: Microbiology Source Type: research

Emergence of carbapenem-resistant Acinetobacter baumannii ST787 in clinical isolates from blood in a tertiary teaching hospital in Northern Taiwan
Conclusion To the best of our knowledge, this study is the first to describe the microbiological characteristics of CRAB ST787, which carried high genetic resistance to carbapenem, but remained susceptible to colistin. CRAB ST787 was the predominant clone in our hospital in the study period. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - June 22, 2017 Category: Microbiology Source Type: research

Citrobacter freundii bacteremia: risk factors of mortality and prevalence of resistance genes
Conclusion For patients with C. freundii bacteremia, carrying the bla TEM-1 resistance gene was an independent risk factor for 28-day mortality. Carbapenems, fourth-generation cephalosporins, amikacin, and quinolones are still reliable agents for drug-resistant strains. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - June 22, 2017 Category: Microbiology Source Type: research

Clinical and Epidemiological Characteristics of Human Parainfluenza Virus Infections of Children in Southern Taiwan
Conclusion The impact caused by HPIVs infections is significant in hospitalized children. In the current study, our results contribute to the epidemiologic, clinical and laboratory information of HPIV infection in children in the important areas of respiratory tract infection that could support the development of optimization management. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - June 22, 2017 Category: Microbiology Source Type: research

Deep sequencing profiles MicroRNAs related to Aspergillus fumigatus infection in lung tissues of mice
Conclusion: We conclude that deep-sequencing small RNAs can uncover miRNA pool-regulating IPA. Our results may lead to further understanding IPA pathogenesis and gain insight into the complexity and diversity of small RNA molecules that regulate immunodeficient IPA. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - June 22, 2017 Category: Microbiology Source Type: research

Ureaplasma spp. in male infertility and its relationship with semen quality and seminal plasma components
Conclusions The infection of Ureaplasma spp. plays an important pathogenic role in male infertility. UPA has higher pathogenicity on the progressive motility and the secretary function of epididymis than UUR. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - June 22, 2017 Category: Microbiology Source Type: research

Routine CD4 monitoring in HIV patients with viral suppression: is it really necessary? A Portuguese cohort
Conclusions The probability of a CD4 count <200cells/μL in an HIV-infected patient with viral suppression and CD4 ≥350cells/μL was very low. These data suggests less frequent monitoring of CD4 counts in these patients. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - June 22, 2017 Category: Microbiology Source Type: research

Intestinal parasitic infections: current status and associated risk factors among school aged children in an archetypal African urban slum in Nigeria
Conclusion Intestinal parasitic infections are very severe among school aged children in the urban slums, thus regular mass de-worming programs, health education, and the provision of safe drinking water is recommended to combat IPIs among the school aged children. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - June 22, 2017 Category: Microbiology Source Type: research

The clinical and microbiological characteristics of infections in burn patients from the Formosa Fun Coast Dust Explosion
Conclusions Waterborne bacteria should be considered in patients of burns with possible water contact. Empirical broad-spectrum antibiotics should be considered for patients who were hospitalized for severe sepsis, or septic shock with a large burn. Antibiotic treatment should be administered based on the specific pathogens and their detection points. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - June 22, 2017 Category: Microbiology Source Type: research

Prevalence of and risk factors for nasal methicillin-resistant Staphylococcus aureus colonization among children in central Taiwan
Conclusion An increasing trend of MRSA nasal carriage rate in Taiwan had been brought forward, however, it was not observed in central Taiwan during the period of 2005 to 2010. We found a summer peak on both MRSA and MSSA carriages. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - June 22, 2017 Category: Microbiology Source Type: research

Characteristics of scrub typhus, murine typhus, and Q fever among elderly patients: prolonged prothrombin time as a predictor for severity
Conclusion The elderly cases with scrub typhus, murine typhus, or acute Q fever would be more likely to have severe complications, for which prothrombin time prolongation is an important predictor for severe complications. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - June 22, 2017 Category: Microbiology Source Type: research

Analyses of clinical and laboratory characteristics of dengue adults at their hospital presentations based on the World Health Organization clinical-phase framework: Emphasizing risk of severe dengue in the elderly
Conclusions Elderly had lower frequency of classical dengue symptoms, yet were at higher risk of development of severe dengue during their early dengue course. A small number of patients developed severe dengue at the WHO-proposed recovery phase. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - June 22, 2017 Category: Microbiology Source Type: research

Viral dynamics of persistent hepatitis C virus infection in high-sensitive reporter cells resemble patient ’s viremia
Conclusion Cultivated HCV in the highly sensitive NS3/4-based SEAP reporter cells could establish persistence, which might mimic the viral dynamics from acute to chronic infections in hepatitis C patients. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - June 20, 2017 Category: Microbiology Source Type: research

A rarely considered diagnosis of unknown fever, disseminated lymphadenopathy and chronic peritonitis in Taiwan: Whipple ’s Disease
Publication date: Available online 20 June 2017 Source:Journal of Microbiology, Immunology and Infection Author(s): Guan-Jhou Chen, Ching-Yao Yang, Chien-Yuan Chen, Sung-Ching Pan, Po-Ren Hsueh, Shan-Chwen Chang (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - June 20, 2017 Category: Microbiology Source Type: research

First Report of OXA-48 Carbapenemase-Producing Escherichia coli in Taiwan
Publication date: Available online 20 June 2017 Source:Journal of Microbiology, Immunology and Infection Author(s): Ya-Ting Jao, Wen-Hung Wang, Angela Wang, L, Kris Siu, Po-Liang Lu (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - June 20, 2017 Category: Microbiology Source Type: research

Zoonotic potential of Helicobacter spp
Publication date: Available online 20 June 2017 Source:Journal of Microbiology, Immunology and Infection Author(s): Irena Mladenova- Hristova, Olga Grekova, Ami Patel The genus Helicobacter contains more than 35 species. Helicobacter pylori is the most important in terms of human health. Discovery of these helicobacters gives opportunity to understand the relationship between these bacteria which colonise the animal and human gut and their effect on the host. Infection with Helicobacter spp. and the associated diseases in their hosts allow us to study the pathogenic mechanisms. The potential zoonotic pathway for the trans...
Source: Journal of Microbiology, Immunology and Infection - June 20, 2017 Category: Microbiology Source Type: research

Identification of a panel of serum protein markers in early stage of sepsis and its validation in a cohort of patients
Conclusion We have identified a panel of ten potential sepsis marker proteins biologically connected and validated in a large number of patients, whose analysis could be considered as a complementary tool for the diagnosis of sepsis. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - June 13, 2017 Category: Microbiology Source Type: research

Cisplatin along with herbal drug treatment reduces the percentage of regulatory T cells and decreased the severity of experimental visceral leishmaniasis
Conclusion In this manner, results acquired recommend that the decrease in percentage of T reg cells may further help the antileishmanial remedial impact of cisplatin alongside natural medications. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - June 9, 2017 Category: Microbiology Source Type: research

The recognition and characterisation of Finnish Clostridium difficile isolates resembling PCR-ribotype 027
Conclusion Our results show a high diversity within 28 Finnish RT027-like C. difficile isolates, with twelve CE-ribotyping profiles and eleven STs. MLVA revealed the regional spread of RTs 016, 027, 176 and F3. The presence of Δ117 in the tcdC gene in eight non-027 RTs highlights the importance of careful interpretation of the results from molecular systems targeting this site in the genome of C. difficile and the need of strain typing for epidemiological purposes. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - May 24, 2017 Category: Microbiology Source Type: research

Anti-apoptotic activity of Japanese encephalitis virus NS5 protein in human medulloblastoma cells treated with interferon- β
Conclusions The results indicated Hsp70 up-regulation by JEV NS5 not only involved in type I IFN antagonism, but also responded to the anti-apoptotic action of JEV NS5 protein through the blocking IFN-β-induced p38 MAPK/STAT1-mediated apoptosis. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - May 19, 2017 Category: Microbiology Source Type: research

Corrigendum to “Rates of susceptibility of carbapenems, ceftobiprole, and colistin against clinically important bacteria collected from intensive care units in 2007: Results from the Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART)” [J Microbiol Immunol Infect 49 (2016) 969–976]
Publication date: Available online 17 March 2017 Source:Journal of Microbiology, Immunology and Infection Author(s): Shio-Shin Jean, Wen-Sen Lee, Kwok-Woon Yu, Chun-Hsing Liao, Chin-Wan Hsu, Feng-Yi Chang, Wen-Chien Ko, Ray-Jade Chen, Jiunn-Jong Wu, Yen-Hsu Chen, Yao-Shen Chen, Jien-Wei Liu, Min-Chi Lu, Carlos Lam, Cheng-Yi Liu, Po-Ren Hsueh (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - May 17, 2017 Category: Microbiology Source Type: research

Immunogenicity and safety of the new reduced-dose tetanus –diphtheria vaccine in healthy Korean adolescents: A comparative active control, double-blind, randomized, multicenter phase III study
Conclusion The new Td vaccine is highly immunogenic and safe, and this new Td vaccine can be effectively used for preventing diphtheria and tetanus. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - May 17, 2017 Category: Microbiology Source Type: research

Improving dengue viral antigens detection in dengue patient serum specimens using a low pH glycine buffer treatment
Conclusion Inclusion of a low-pH glycine buffer treatment step in the commercially available Ag-ELISA is crucial for clinical diagnosis and E-containing viral particles could be a valuable target for acute DENV diagnosis, similar to NS1 detection. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - May 17, 2017 Category: Microbiology Source Type: research

Polymorphisms of the IL-6, IL-8 and IL-10 genes and the risk of gastric pathology in patients infected with Helicobacter pylori
Conclusion We demonstrated that polymorphisms in the IL-8 gene was significantly associated with H. pylori infection. Furthermore, polymorphisms in the IL-8 and IL-10 genes were associated with an enhanced risk of peptic ulcer disease in H. pylori-positive patients. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - May 17, 2017 Category: Microbiology Source Type: research

Clinical features, antifungal susceptibility, and outcome of Candida guilliermondii fungemia: an experience in a tertiary hospital in mid-Taiwan
Conclusion Despite the lower mortality rate associated with C. guilliermondii fungemia, the removal of a central venous catheter remained an independent factor influencing the outcome of patients. The clinical significance of less susceptibility of C. guilliermondii to triazoles and echinocandins remains to be elucidated. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - May 17, 2017 Category: Microbiology Source Type: research

Immunization with outer membrane proteins (OprF and OprI) and flagellin B  protects mice from pulmonary infection with mucoid and nonmucoid Pseudomonas aeruginosa
Conclusion Our data showed that mice immunized with OprF/OprI or OprF/OprI and flagellin B are significantly protected from infection caused by mucoid and nonmucoid strains of P. aeruginosa. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - March 11, 2017 Category: Microbiology Source Type: research

A case of Mycoplasma hominis disseminated infection in a human immunodeficiency virus-1-infected pregnant woman with hypogammaglobulinemia
Publication date: February 2017 Source:Journal of Microbiology, Immunology and Infection, Volume 50, Issue 1 Author(s): Sara Fernández, David Nicolás, Juan M. Pericás, Pedro Castro Rebollo, Jordi Vila, Josep M. Miró, José L. Blanco, Josep M. Nicolás (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - March 9, 2017 Category: Microbiology Source Type: research

Toll-like receptor 1 N248S polymorphism affects T helper 1 cytokine production and is associated with serum immunoglobulin E levels in Taiwanese allergic patients
Conclusion Our data suggest that the TLR1 N248S polymorphism might play a role in Th1/Th2 differentiation, and the determination of serum IgE levels. However, interactions with other genetic and environmental factors might be required to contribute to risk of allergic diseases in our population. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - March 9, 2017 Category: Microbiology Source Type: research

Recombinant bacille Calmette –Guerin coexpressing Ag85b, CFP10, and interleukin-12 elicits effective protection against Mycobacterium tuberculosis
Conclusion In this study, we demonstrated that the novel rBCG2 vaccine may be a promising candidate vaccine against M. tuberculosis infection. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - March 9, 2017 Category: Microbiology Source Type: research

Galleria mellonella as an in  vivo model for assessing the efficacy of antimicrobial agents against Enterobacter cloacae infection
Conclusion The G. mellonella infection model has the potential to be used to facilitate the in vivo study of host–pathogen interactions in E. cloacae and the efficacy of antibacterial agents. (Source: Journal of Microbiology, Immunology and Infection)
Source: Journal of Microbiology, Immunology and Infection - March 9, 2017 Category: Microbiology Source Type: research