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ddPCR enables rapid detection of bloodstream infections in patients on home parenteral nutrition: A prospective cohort study
CONCLUSION: ddPCR showed a high sensitivity and specificity relative to blood cultures and enables rapid pathogen detection and characterization. Clinical studies should explore if integrated ddPCR and blood culture outcomes enables a more rapid pathogen guided CLABSI treatment and enhancing patient outcomes.PMID:38575399 | DOI:10.1016/j.jmii.2024.03.003 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - April 4, 2024 Category: Microbiology Authors: Veerle E L M Gillis Daisy Dalloyaux Rene H M Te Morsche Jakko van Ingen Özcan Sir Chantal P Rovers Yannick Wouters Geert J A Wanten Source Type: research

Molnupiravir for the treatment of COVID-19 outpatients: An updated meta-analysis
CONCLUSIONS: Molnupiravir does not decrease mortality and hospitalization rates in immunized patients with COVID-19. However, it does shorten the disease course and increases the recovery rate. The use of molnupiravir will need to be considered on a case-by-case basis in the context of the prevailing social circumstances, the resource setting, drug costs, and the healthcare burden.PMID:38555274 | DOI:10.1016/j.jmii.2024.03.002 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - March 30, 2024 Category: Microbiology Authors: Huzaifa Ahmad Cheema Saleha Abdul Rab Momina Butt Uzair Jafar Abia Shahid Aqeeb Ur Rehman Ka Yiu Lee Syeda Sahra Ranjit Sah Source Type: research

Ten-year epidemiology and risk factors of cytomegalovirus infection in hematopoietic stem cell transplantation patients in Taiwan
CONCLUSION: The study revealed a significant disparity in terms of the incidence, risk factors, and clinical outcomes of CMV infection and disease between auto and allo-HSCT patients. These findings underscore the importance of considering these factors in the management of HSCT recipients to improve outcomes related to CMV infections.PMID:38503632 | DOI:10.1016/j.jmii.2024.02.005 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - March 19, 2024 Category: Microbiology Authors: Yi-Che Huang Fei-Yuan Hsiao Shang-Ting Guan Ming Yao Chia-Jen Liu Tzu-Ting Chen Tung-Liang Lin Yi-Chang Liu Tsai-Yun Chen Ying-Chung Hong Ming-Chun Ma Tran-Der Tan Chuan-Cheng Wang Yi-Ying Wu Po-Wei Liao Yi-Feng Wu Yi-Yang Chen Yuan-Bin Yu Yao-Yu Hsieh Mi Source Type: research