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Ribotypes and antimicrobial susceptibility profiles of clinical Clostridioides difficile isolates: A multicenter, laboratory-based surveillance in Taiwan, 2019-2021
CONCLUSIONS: Vancomycin, fidaxomicin, and metronidazole remain in vitro effective against clinical C. difficile isolates in Taiwan. The reservoirs and genetic relatedness of two major RTs with zoonotic potentials, RT 078/126 and 014/020, warrant further investigations.PMID:38135646 | DOI:10.1016/j.jmii.2023.12.004 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - December 22, 2023 Category: Microbiology Authors: Chin-Shiang Tsai Po-Liang Lu Min-Chi Lu Tai-Chin Hsieh Wei-Ting Chen Jann-Tay Wang Wen-Chien Ko Source Type: research

Safety and effectiveness of remdesivir for the treatment of COVID-19 patients with end-stage renal disease: A retrospective cohort study
CONCLUSION: Remdesivir is safe for use in patients with COVID-19 and ESRD; no increased adverse effects were noted compared with patients without ESRD. However, the effectiveness of remdesivir use in patients with COVID-19 and ESRD remains uncertain.PMID:38135644 | DOI:10.1016/j.jmii.2023.12.003 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - December 22, 2023 Category: Microbiology Authors: Yan-Bo Huang Chip-Jin Ng Cheng-Hsun Chiu Chung-Hsien Chaou Shi-Ying Gao Shou-Yen Chen Source Type: research

Recommendations and guidelines for endoscope reprocessing: Current position statement of digestive endoscopic society of Taiwan
J Microbiol Immunol Infect. 2023 Dec 11:S1684-1182(23)00215-3. doi: 10.1016/j.jmii.2023.12.001. Online ahead of print.ABSTRACTReprocessing of gastrointestinal (GI) endoscopes and accessories is an essential part of patient safety and quality control in GI endoscopy centers. However, current endoscopic reprocessing guidelines or procedures are not adequate to ensure patient-safe endoscopy. Approximately 5.4 % of the clinically used duodenoscopes remain contaminated with high-concern microorganisms. Thus, the Digestive Endoscopy Society of Taiwan (DEST) sets standards for the reprocessing of GI endoscopes and accessories in ...
Source: Journal of Microbiology, Immunology, and Infection - December 22, 2023 Category: Microbiology Authors: Wei-Kuo Chang Chen-Ling Peng Yen-Wei Chen Cheuk-Kay Sun Chieh-Chang Chen Tao-Chieh Liu Yin-Yi Chu I-Fang Tsai Chen-Shuan Chung Hsiao-Fen Lin Fang-Yu Hsu Wei-Chen Tai Hsi-Chang Lee Hsu-Heng Yen E-Ming Wang Shu-Hui Chen Cheng-Hsin Chu Ming-Jen Chen Ching-Li Source Type: research

Real-world effectiveness of full and booster mRNA vaccination for coronavirus disease 2019 against disease severity during the delta- and omicron-dominant phases: A propensity score-matched cohort study using the nationwide registry data in Japan
CONCLUSIONS: Full vaccination reduced disease severity during the delta- and omicron-dominant phases; booster vaccination did not further enhance the protective effects against disease progression during the omicron-dominant phase compared to full vaccination. Future vaccine strategies and policy decisions should consider preventing infection or disease progression in the target population, as well as the characteristics of the dominant variant in that phase.PMID:38123439 | DOI:10.1016/j.jmii.2023.12.002 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - December 20, 2023 Category: Microbiology Authors: Tetsuya Suzuki Yusuke Asai Shinya Tsuzuki Hidetoshi Nomoto Nobuaki Matsunaga Eiichi N Kodama Kayoko Hayakawa Norio Ohmagari Source Type: research

Liver dysfunction and clinical outcomes of unvaccinated COVID-19 patients with and without chronic hepatitis B
CONCLUSIONS: CHB patients had higher ALT levels and longer hospitalizations during COVID-19. Higher AST levels predict severe COVID-19 and ICU admission.PMID:38110321 | DOI:10.1016/j.jmii.2023.11.003 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - December 18, 2023 Category: Microbiology Authors: Hao-Che Chang Tung-Hung Su Yu-Tsung Huang Chun-Ming Hong Wang-Huei Sheng Po-Ren Hsueh Jia-Horng Kao Source Type: research