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Clinical impact of the combination of rapid species identification and antifungal stewardship intervention in adults with candidemia
CONCLUSION: Rapid diagnostic workflow and antifungal stewardship provided by infectious disease specialists can promote early initiation of antifungal therapy and improve outcome for adults with candidemia.PMID:37723015 | DOI:10.1016/j.jmii.2023.08.014 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - September 18, 2023 Category: Microbiology Authors: Hao-En Jan Ching-Lung Lo Jen-Chieh Lee Ming-Chi Li Wen-Liang Lin Wen-Chien Ko Nan-Yao Lee Source Type: research

Risk factors of Omicron variant associated acute encephalitis/encephalopathy in children
CONCLUSIONS: Most cases of COVID-19-associated acute encephalitis/encephalopathy showed no evidence of direct viral invasion but associations with older age, increased peripheral neutrophil, and serum procalcitonin. These findings may imply the neutrophil-mediated systemic inflammatory response plays an important role on central nerve system, leading to cerebral dysfunction.PMID:37709632 | DOI:10.1016/j.jmii.2023.08.010 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - September 14, 2023 Category: Microbiology Authors: Chong-Wei Huang Jainn-Jim Lin Chen-Yen Kuo Kuang-Lin Lin Yhu-Chering Huang Cheng-Hsun Chiu Yi-Ching Chen Chih-Ho Chen Yu-Chia Hsieh Source Type: research

Molecular characteristics and clinical features of Staphylococcus epidermidis healthcare-associated late-onset bacteremia among infants hospitalized in neonatal intensive care units
CONCLUSIONS: More than 90% of S. epidermidis bloodstream isolates from infants in NICU in Taiwan were resistant to oxacillin. Though diverse, more than 90% of the isolates (episodes) belonged to CC2. No statistically significant differences were found in terms of clinical characteristics among the infants infected with genetically different strains.PMID:37709633 | DOI:10.1016/j.jmii.2023.08.005 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - September 14, 2023 Category: Microbiology Authors: Yi-Hsuan Huang Yu-Rou Yeh Rey-In Lien Ming-Chou Chiang Yhu-Chering Huang Source Type: research

Risk factors of Omicron variant associated acute encephalitis/encephalopathy in children
CONCLUSIONS: Most cases of COVID-19-associated acute encephalitis/encephalopathy showed no evidence of direct viral invasion but associations with older age, increased peripheral neutrophil, and serum procalcitonin. These findings may imply the neutrophil-mediated systemic inflammatory response plays an important role on central nerve system, leading to cerebral dysfunction.PMID:37709632 | DOI:10.1016/j.jmii.2023.08.010 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - September 14, 2023 Category: Microbiology Authors: Chong-Wei Huang Jainn-Jim Lin Chen-Yen Kuo Kuang-Lin Lin Yhu-Chering Huang Cheng-Hsun Chiu Yi-Ching Chen Chih-Ho Chen Yu-Chia Hsieh Source Type: research

Molecular characteristics and clinical features of Staphylococcus epidermidis healthcare-associated late-onset bacteremia among infants hospitalized in neonatal intensive care units
CONCLUSIONS: More than 90% of S. epidermidis bloodstream isolates from infants in NICU in Taiwan were resistant to oxacillin. Though diverse, more than 90% of the isolates (episodes) belonged to CC2. No statistically significant differences were found in terms of clinical characteristics among the infants infected with genetically different strains.PMID:37709633 | DOI:10.1016/j.jmii.2023.08.005 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - September 14, 2023 Category: Microbiology Authors: Yi-Hsuan Huang Yu-Rou Yeh Rey-In Lien Ming-Chou Chiang Yhu-Chering Huang Source Type: research

Risk factors of Omicron variant associated acute encephalitis/encephalopathy in children
CONCLUSIONS: Most cases of COVID-19-associated acute encephalitis/encephalopathy showed no evidence of direct viral invasion but associations with older age, increased peripheral neutrophil, and serum procalcitonin. These findings may imply the neutrophil-mediated systemic inflammatory response plays an important role on central nerve system, leading to cerebral dysfunction.PMID:37709632 | DOI:10.1016/j.jmii.2023.08.010 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - September 14, 2023 Category: Microbiology Authors: Chong-Wei Huang Jainn-Jim Lin Chen-Yen Kuo Kuang-Lin Lin Yhu-Chering Huang Cheng-Hsun Chiu Yi-Ching Chen Chih-Ho Chen Yu-Chia Hsieh Source Type: research

Molecular characteristics and clinical features of Staphylococcus epidermidis healthcare-associated late-onset bacteremia among infants hospitalized in neonatal intensive care units
CONCLUSIONS: More than 90% of S. epidermidis bloodstream isolates from infants in NICU in Taiwan were resistant to oxacillin. Though diverse, more than 90% of the isolates (episodes) belonged to CC2. No statistically significant differences were found in terms of clinical characteristics among the infants infected with genetically different strains.PMID:37709633 | DOI:10.1016/j.jmii.2023.08.005 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - September 14, 2023 Category: Microbiology Authors: Yi-Hsuan Huang Yu-Rou Yeh Rey-In Lien Ming-Chou Chiang Yhu-Chering Huang Source Type: research

Risk factors of Omicron variant associated acute encephalitis/encephalopathy in children
CONCLUSIONS: Most cases of COVID-19-associated acute encephalitis/encephalopathy showed no evidence of direct viral invasion but associations with older age, increased peripheral neutrophil, and serum procalcitonin. These findings may imply the neutrophil-mediated systemic inflammatory response plays an important role on central nerve system, leading to cerebral dysfunction.PMID:37709632 | DOI:10.1016/j.jmii.2023.08.010 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - September 14, 2023 Category: Microbiology Authors: Chong-Wei Huang Jainn-Jim Lin Chen-Yen Kuo Kuang-Lin Lin Yhu-Chering Huang Cheng-Hsun Chiu Yi-Ching Chen Chih-Ho Chen Yu-Chia Hsieh Source Type: research

Molecular characteristics and clinical features of Staphylococcus epidermidis healthcare-associated late-onset bacteremia among infants hospitalized in neonatal intensive care units
CONCLUSIONS: More than 90% of S. epidermidis bloodstream isolates from infants in NICU in Taiwan were resistant to oxacillin. Though diverse, more than 90% of the isolates (episodes) belonged to CC2. No statistically significant differences were found in terms of clinical characteristics among the infants infected with genetically different strains.PMID:37709633 | DOI:10.1016/j.jmii.2023.08.005 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - September 14, 2023 Category: Microbiology Authors: Yi-Hsuan Huang Yu-Rou Yeh Rey-In Lien Ming-Chou Chiang Yhu-Chering Huang Source Type: research

Caecum OX40+CD4 T-cell subset associates with mucosal damage and key markers of disease in treated HIV-infection
CONCLUSION: High frequencies of caecum OX40+CD4 T-cells are found in people with HIV (PWH) and successful viral control. Interestingly, this cellular subset reflects key markers of disease and peripheral T-cell activation, as well as HIV-driven mucosal damage. OX40+CD4 T-cells deserve further investigation since they could expand because of T-cell homeostatic proliferation and relate to the Th22/Th17 gut mucosal ratio.PMID:37704537 | DOI:10.1016/j.jmii.2023.08.011 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - September 13, 2023 Category: Microbiology Authors: Isaac Rosado-S ánchez In és Herrero-Fernández Salvador Sobrino Ana E Carvajal Miguel Genebat Laura Taranc ón-Díez Mar ía Carmen Garcia-Guerrero Mar ía Carmen Puertas Roc ío M de Pablos Roc ío Ruiz Javier Martinez-Picado Manuel Leal Yolanda M Pach Source Type: research

Investigation of a COVID-19 cluster involving vertical transmission in a residential building, Taiwan, 2021
J Microbiol Immunol Infect. 2023 Sep 9:S1684-1182(23)00159-7. doi: 10.1016/j.jmii.2023.08.009. Online ahead of print.ABSTRACTWe investigated a COVID-19 cluster involved seven case-patients lived in a high-rise building in September 2021. We used a simplified tracer-gas experiment and virus sequencing to establish the link between case-patients. Vertical transmission among vertically aligned apartments on different floors in a building was the most likely route of transmission.PMID:37699780 | DOI:10.1016/j.jmii.2023.08.009 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - September 12, 2023 Category: Microbiology Authors: Hsin-Yi Wei Cheng-Ping Chang Ming-Tsan Liu Jung-Jung Mu Chia-Ping Su Source Type: research

Investigation of a COVID-19 cluster involving vertical transmission in a residential building, Taiwan, 2021
J Microbiol Immunol Infect. 2023 Sep 9:S1684-1182(23)00159-7. doi: 10.1016/j.jmii.2023.08.009. Online ahead of print.ABSTRACTWe investigated a COVID-19 cluster involved seven case-patients lived in a high-rise building in September 2021. We used a simplified tracer-gas experiment and virus sequencing to establish the link between case-patients. Vertical transmission among vertically aligned apartments on different floors in a building was the most likely route of transmission.PMID:37699780 | DOI:10.1016/j.jmii.2023.08.009 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - September 12, 2023 Category: Microbiology Authors: Hsin-Yi Wei Cheng-Ping Chang Ming-Tsan Liu Jung-Jung Mu Chia-Ping Su Source Type: research

Prognostic factors for poor outcomes in patients with severe COVID-19 treated with remdesivir plus dexamethasone in Taiwan
CONCLUSION: High disease severity on admission and delayed initiation of remdesivir therapy were associated with poor outcomes in COVID-19 patients treated with remdesivir and dexamethasone.PMID:37696685 | DOI:10.1016/j.jmii.2023.08.008 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - September 11, 2023 Category: Microbiology Authors: Yi-Hsuan Lai Yi-Chih Lee I-Ren Chen Shih-Neng Lin Yuh-Lih Chang Chih-Chia Lu Ping-Feng Wu Yi-Tsung Lin Source Type: research

Prognostic factors for poor outcomes in patients with severe COVID-19 treated with remdesivir plus dexamethasone in Taiwan
CONCLUSION: High disease severity on admission and delayed initiation of remdesivir therapy were associated with poor outcomes in COVID-19 patients treated with remdesivir and dexamethasone.PMID:37696685 | DOI:10.1016/j.jmii.2023.08.008 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - September 11, 2023 Category: Microbiology Authors: Yi-Hsuan Lai Yi-Chih Lee I-Ren Chen Shih-Neng Lin Yuh-Lih Chang Chih-Chia Lu Ping-Feng Wu Yi-Tsung Lin Source Type: research

Genetic surveillance and outcomes of pyrazinamide and fluoroquinolones-resistant tuberculosis in Taiwan
CONCLUSION: We concluded that routine PZA and FQ susceptibility tests are recommended for guiding the treatment of TB.PMID:37690869 | DOI:10.1016/j.jmii.2023.08.013 (Source: Journal of Microbiology, Immunology, and Infection)
Source: Journal of Microbiology, Immunology, and Infection - September 10, 2023 Category: Microbiology Authors: Hsin-Ting Huang Wan-Hsuan Lin Tai-Hua Chan Ruwen Jou Source Type: research