Early Mobilization in the ICU and Diabetes: A Bittersweet Concoction?
Am J Respir Crit Care Med. 2024 May 19. doi: 10.1164/rccm.202405-0964ED. Online ahead of print.NO ABSTRACTPMID:38763507 | DOI:10.1164/rccm.202405-0964ED (Source: Respiratory Care)
Source: Respiratory Care - May 19, 2024 Category: Respiratory Medicine Authors: Matthew F Mart E Wesley Ely Source Type: research
The Risk of Secondary Spontaneous Pneumothorax in Patients with Chronic Obstructive Pulmonary Disease in Taiwan
CONCLUSION: Our study revealed an elevated risk of SSP in patients with COPD. It has also been suggested that COPD patients with comorbidities, such as atrial fibrillation, congestive heart failure, coronary artery disease, diabetes mellitus, hypertension, and cancer, have an increased risk of developing SSP.PMID:38763446 | DOI:10.1016/j.rmed.2024.107672 (Source: Respiratory Care)
Source: Respiratory Care - May 19, 2024 Category: Respiratory Medicine Authors: Kuang-Ming Liao Chong-Chi Chiu Hsueh-Yi Lu Source Type: research
Impact of High Dose Early Mobilization on Outcomes for Patients with Diabetes: A Secondary Analysis of the TEAM Trial
CONCLUSIONS: In this secondary analysis of the TEAM trial, in patients with diabetes, a high dose early mobilization strategy did not significantly decrease the number of days alive and out of hospital at day 180 but it increased 180-day mortality.PMID:38763167 | DOI:10.1164/rccm.202312-2289OC (Source: Respiratory Care)
Source: Respiratory Care - May 19, 2024 Category: Respiratory Medicine Authors: Ary Serpa Neto Michael Bailey Daniel Seller Alicia Agli Rinaldo Bellomo Kathy Brickell Tessa Broadley Heidi Buhr Belinda J Gabbe Doug W Gould Meg Harrold Alisa M Higgins Sally Hurford Theodore J Iwashyna Alistair D Nichol Jeffrey J Presneill Stefan J Scha Source Type: research
Impact of High Dose Early Mobilization on Outcomes for Patients with Diabetes: A Secondary Analysis of the TEAM Trial
CONCLUSIONS: In this secondary analysis of the TEAM trial, in patients with diabetes, a high dose early mobilization strategy did not significantly decrease the number of days alive and out of hospital at day 180 but it increased 180-day mortality.PMID:38763167 | DOI:10.1164/rccm.202312-2289OC (Source: Am J Respir Crit Car...)
Source: Am J Respir Crit Car... - May 19, 2024 Category: Intensive Care Authors: Ary Serpa Neto Michael Bailey Daniel Seller Alicia Agli Rinaldo Bellomo Kathy Brickell Tessa Broadley Heidi Buhr Belinda J Gabbe Doug W Gould Meg Harrold Alisa M Higgins Sally Hurford Theodore J Iwashyna Alistair D Nichol Jeffrey J Presneill Stefan J Scha Source Type: research
Early Mobilization in the ICU and Diabetes: A Bittersweet Concoction?
Am J Respir Crit Care Med. 2024 May 19. doi: 10.1164/rccm.202405-0964ED. Online ahead of print.NO ABSTRACTPMID:38763507 | DOI:10.1164/rccm.202405-0964ED (Source: Am J Respir Crit Car...)
Source: Am J Respir Crit Car... - May 19, 2024 Category: Intensive Care Authors: Matthew F Mart E Wesley Ely Source Type: research
Association between long-term exposure to air pollution and diabetic retinopathy: Evidence from the Fujian Eye Study
CONCLUSIONS: These findings showed that long-term exposure to ambient particulate matter and NO2 was associated with a high DR risk in Fujian province, where ambient air pollution is relatively low.PMID:38763052 | DOI:10.1016/j.ecoenv.2024.116459 (Source: Ecotoxicology and Environmental Safety)
Source: Ecotoxicology and Environmental Safety - May 19, 2024 Category: Environmental Health Authors: Bo Zuo Qinrui Hu Yixue Wu Xiaoxin Li Bin Wang Meilin Yan Yang Li Source Type: research
Antidiabetic properties of Caffeoylmalic acid, a bioactive natural compound isolated from Urtica dioica
Fitoterapia. 2024 May 17:106024. doi: 10.1016/j.fitote.2024.106024. Online ahead of print.ABSTRACTThe uncontrolled hyperglycemia that characterizes diabetes mellitus (DM) causes several complications in the organism. DM is among the major causes of deaths, and the limited efficacy of current treatments push the search for novel drug candidates, also among natural compounds. We focused our attention on caffeoylmalic acid, a phenolic derivative extracted from Urtica dioica, a plant investigated for its potential against type 2 DM. This compound was tested for its antidiabetic activity in vitro through a glucose uptake assay,...
Source: Fitoterapia - May 19, 2024 Category: Biochemistry Authors: Gauhar Rehman Ilman Khan Abdur Rauf Umer Rashid Arshma Siddique Syed Muhammad Mukarram Shah Zuneera Akram Najla AlMasoud Taghrid S Alomar Zafar Ali Shah Giovanni Ribaudo Source Type: research
Endoplasmic reticulum-resident selenoproteins and their roles in glucose and lipid metabolic disorders
Biochim Biophys Acta Mol Basis Dis. 2024 May 17:167246. doi: 10.1016/j.bbadis.2024.167246. Online ahead of print.ABSTRACTGlucose and lipid metabolic disorders (GLMDs), such as diabetes, dyslipidemia, metabolic syndrome, nonalcoholic fatty liver disease, and obesity, are significant public health issues that negatively impact human health. The endoplasmic reticulum (ER) plays a crucial role at the cellular level for lipid and sterol biosynthesis, intracellular calcium storage, and protein post-translational modifications. Imbalance and dysfunction of the ER can affect glucose and lipid metabolism. As an essential trace elem...
Source: Biochimica et Biophysica Acta - May 19, 2024 Category: Biochemistry Authors: Zhan Shi Ziyu Han Jingyi Chen Ji-Chang Zhou Source Type: research
When should a patient with obesity be referred to endocrinology? Current indications for bariatric surgery
Aten Primaria. 2024 May 18;56(7):102961. doi: 10.1016/j.aprim.2024.102961. Online ahead of print.ABSTRACTBariatric surgery (BS) has been shown to be effective and efficient, but only 1% of selected patients will ever receive it. Compared to medical treatment of obesity, BS has demonstrated greater long-term sustained weight loss, a reduction in both total and cardiovascular (CV) mortality, improvement or remission of CV risk factors and other comorbidities associated with obesity, as well as improved mobility and quality of life. BS presents similar risks to other abdominal surgeries, with obesity as an added risk factor. ...
Source: Atencion Primaria - May 19, 2024 Category: Primary Care Authors: Laura Rius Acebes Myriam S ánchez-Pacheco-Tardon Domingo Orozco Beltr án Source Type: research
Impact of High Dose Early Mobilization on Outcomes for Patients with Diabetes: A Secondary Analysis of the TEAM Trial
CONCLUSIONS: In this secondary analysis of the TEAM trial, in patients with diabetes, a high dose early mobilization strategy did not significantly decrease the number of days alive and out of hospital at day 180 but it increased 180-day mortality.PMID:38763167 | DOI:10.1164/rccm.202312-2289OC (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - May 19, 2024 Category: Respiratory Medicine Authors: Ary Serpa Neto Michael Bailey Daniel Seller Alicia Agli Rinaldo Bellomo Kathy Brickell Tessa Broadley Heidi Buhr Belinda J Gabbe Doug W Gould Meg Harrold Alisa M Higgins Sally Hurford Theodore J Iwashyna Alistair D Nichol Jeffrey J Presneill Stefan J Scha Source Type: research
Early Mobilization in the ICU and Diabetes: A Bittersweet Concoction?
Am J Respir Crit Care Med. 2024 May 19. doi: 10.1164/rccm.202405-0964ED. Online ahead of print.NO ABSTRACTPMID:38763507 | DOI:10.1164/rccm.202405-0964ED (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - May 19, 2024 Category: Respiratory Medicine Authors: Matthew F Mart E Wesley Ely Source Type: research
Inadequate linear catch-up growth in children born small for gestational age: Influencing factors and underlying mechanisms
Rev Endocr Metab Disord. 2024 May 20. doi: 10.1007/s11154-024-09885-x. Online ahead of print.ABSTRACTA minority of children born small for gestational age (SGA) may experience catch-up growth failure and remain short in adulthood. However, the underlying causes and mechanisms of this phenomenon are not yet fully comprehended. We reviewed the present state of research concerning the growth hormone-insulin-like growth factor axis and growth plate in SGA children who fail to achieve catch-up growth. Additionally, we explored the factors influencing catch-up growth in SGA children and potential molecular mechanisms involved. F...
Source: ENDOCR REV - May 19, 2024 Category: Endocrinology Authors: Anran Tian Fucheng Meng Sujuan Li Yichi Wu Cai Zhang Xiaoping Luo Source Type: research
β-hydroxybutyrate alleviates neurological deficits by restoring glymphatic and inflammation after subarachnoid hemorrhage in mice
CONCLUSION: The study reveals a novel mechanism that BHB treatment mitigates neurologic impairment in SAH mice. We propose that BHB may play a neuroprotective effect by enhancing glymphatic system function and attenuating neuroinflammatory subarachnoid hemorrhage.PMID:38763355 | DOI:10.1016/j.expneurol.2024.114819 (Source: Experimental Neurology)
Source: Experimental Neurology - May 19, 2024 Category: Neurology Authors: Xiaoli Tan Xiaohong Li Ruhua Li Weiting Meng Zhuoxi Xie Jing Li Yeyu Pang Guilan Huang Li Li Hao Li Source Type: research
Efficacy and Safety of Metformin and Atorvastatin Combination Therapy vs. Monotherapy with Either Drug in Type 2 Diabetes Mellitus and Dyslipidemia Patients (ATOMIC): Double-Blinded Randomized Controlled Trial
CONCLUSION: The addition of atorvastatin to metformin improved HbA1c and LDL-C levels to a significant extent compared to metformin or atorvastatin alone in diabetes and dyslipidemia patients. This study also suggested metformin's preventive effect on the glucose-elevating potential of atorvastatin in patients with type 2 diabetes mellitus and dyslipidemia, insufficiently controlled with exercise and diet. Metformin and atorvastatin combination might be an effective treatment in reducing the CVD risk in patients with both diabetes and dyslipidemia because of its lowering effect on LDL-C and glucose.PMID:38763510 | DOI:10.4...
Source: Diabetes and Metabolism Journal - May 19, 2024 Category: Endocrinology Authors: Jie-Eun Lee Seung Hee Yu Sung Rae Kim Kyu Jeung Ahn Kee-Ho Song In-Kyu Lee Ho-Sang Shon In Joo Kim Soo Lim Doo-Man Kim Choon Hee Chung Won-Young Lee Soon Hee Lee Dong Joon Kim Sung-Rae Cho Chang Hee Jung Hyun Jeong Jeon Seung-Hwan Lee Keun-Young Park Sang Source Type: research
Association of Coronary Computed Tomography-Defined Myocardial Bridge With Pre- and Post-Procedural Fractional Flow Reserve in Patients Undergoing Elective Percutaneous Coronary Intervention
CONCLUSIONS: CCTA-defined MB independently predicted both lower post-PCI FFR as a continuous variable and ischemic FFR as a categorical variable in patients undergoing elective PCI for LAD.PMID:38763754 | DOI:10.1253/circj.CJ-23-0934 (Source: Circulation Journal)
Source: Circulation Journal - May 19, 2024 Category: Cardiology Authors: Tatsuya Sakamoto Eisuke Usui Masahiro Hoshino Masahiro Hada Tatsuhiro Nagamine Yoshihiro Hanyu Kai Nogami Hiroki Ueno Mirei Setoguchi Tomohiro Tahara Kazuki Matsuda Takashi Mineo Nobutaka Wakasa Tomoyo Sugiyama Taishi Yonetsu Tetsuo Sasano Tsunekazu Kakut Source Type: research
