Biolinq Raises $58 Million to Advance Wearable Biosensors Through Pivotal Trial for Metabolic Health Using Precision Microsensor Technology
Biosensor Platform Leverages Silicon Semiconductor Manufacturing for Scale Technology Designed to Provide a Better View of Metabolic Health by Combining Glucose Information with Context Around Activities of Daily Living in One Device $58 Million in Funding Led by Alpha Wave Ventures Biolinq Incorporated, a healthcare technology company pioneering precision multi-analyte biosensors to improve metabolic health, today announced the completion of $58 million in financing led by Alpha Wave Ventures, with participation from Niterra’s corporate venture capital fund jointly operated with Pegasus Tech Ventures and existing invest...
Source: EMR and HIPAA - May 7, 2024 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Alpha Wave Ventures Aphelion Capital AXA IM Alts Biolinq Biolinq Incorporated Dan Bradbury Features Capital Global Health Investment Corporation Health IT Funding Health IT Fundings Health IT Investm Source Type: blogs

The Therapeutic Potential of Transdifferentiation
Transdifferentiation is the use of various techniques to convert a somatic cell of one type directly into a somatic cell of another type. This is an alternative to first using Yamanaka factors to dedifferentiate somatic cells into induced pluripotent stem cells, then guiding differentiation into the desired final somatic cell type. For both differentiation from pluripotency to somatic cell and transdifferentiation between somatic cells, a suitable recipe of factors and altered gene expression must be discovered for any given destination. A few of these protocols are now well known, but the vast majority have yet to be robu...
Source: Fight Aging! - May 6, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Is getting people off weight loss medications the right move?
By RICHARD FRANK Demand for GLP-1 medications soared last year and shows no signs of stopping in 2024. Employers and health plans are understandably anxious about how long they should expect to pay for these pricey drugs. They’re itching for an easy off-ramp. Some solutions are cropping up to pave the way. Many of them claim they can help patients reap the benefits of GLP-1s within a short time frame, and get them off the drugs within 12 months to save costs. But the data doesn’t support that promise. In fact, studies suggest some patients may need to stay on the drugs indefinitely to sustain outcomes while other...
Source: The Health Care Blog - May 6, 2024 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Medical Practice GLP-1s Obesity Richard Frank vida health Source Type: blogs

Fight Aging! Newsletter, May 6th 2024
In conclusion, we found that elevated central aortic stiffness is associated with a greater decline in kidney function in old age. Since aPWV and cSBP both appear to be predictors of eGFR decline, it might be of interest to identify older individuals with elevated aortic stiffness. In this specific population, intensive blood pressure reduction might be justified in order to slow down the process of vascular aging and prevent kidney function decline. « Back to Top Cellular Senescence in Neurodegenerative Conditions https://www.fightaging.org/archives/2024/04/cellular-senescence-in-neurodegenera...
Source: Fight Aging! - May 5, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Lean Digital: General and Long-Term Considerations for Obesity
This series of articles has covered the ways that digital technologies contribute to weight loss. To round out the series, this final article covers general topics applying to the field. Maintaining Success Both surgery and medications help some people lose weight, but a lot of patients gradually gain it back. Some of the technology solutions I cover in this article can be used either by themselves in behavioral changes for weight loss, or to maintain a desired weight after other medical interventions. Virta Health is an example. A recent study showed that it can help people go off of GLP-1 drugs and maintain the weight ...
Source: EMR and HIPAA - May 3, 2024 Category: Information Technology Authors: Andy Oram Tags: AI/Machine Learning Ambulatory Analytics/Big Data Clinical Communication and Patient Experience Health IT Company Healthcare IT Hospital - Health System Telemedicine and Remote Monitoring Atrium Health Bariatrics Behavior Management Source Type: blogs

Lean Digital: How Tracking Feeds Into Behavior Change for Weight Loss
This article is part of a series on today’s philosophies regarding weight change and how digital interventions can help. In this article, we’ll look at the contribution of tracking. The article looks at standards, making sure data meets a useful need, and some particular applications of tracking to metabolic control and diet. Finding Meaning in Data Device manufacturers are finding more and more things to track. While some people love measurements such as steps taken through the day, and there’s even a site called Quantified Self exploiting this fad, most people don’t care about data unless they s...
Source: EMR and HIPAA - May 2, 2024 Category: Information Technology Authors: Andy Oram Tags: AI/Machine Learning Ambulatory Analytics/Big Data Clinical Communication and Patient Experience Health IT Company Healthcare IT Hospital - Health System Telemedicine and Remote Monitoring Behavior Management Behavioral Change Candice Source Type: blogs

Lean Digital: Behavior Change for Weight and Obesity
This article, part of a series about obesity, interviews a number of experts to explore the philosophy and practice of behavioral therapy for obesity. Medical and Behavioral Interactions Dr. Luke Twelves, medical director of the contract research organization Lindus Health, says, “Obesity is a multifactor disease.” He believes that technology helps people take control of their own treatment. For instance, a continuous glucose monitor (CGM) allows patients to decide what food or medication they need at each moment in the day. A similar viewpoint was cited by Eric Bormel, a director in the Healthcare Group at S...
Source: EMR and HIPAA - May 1, 2024 Category: Information Technology Authors: Andy Oram Tags: AI/Machine Learning Ambulatory Analytics/Big Data Clinical Communication and Patient Experience Health IT Company Healthcare IT Hospital - Health System Telemedicine and Remote Monitoring 9amHealth Amwell Avantika Waring Behavior M Source Type: blogs

FTC Again Polices FDA's Laziness With Improper Orange Book Listings for Diabetes, Weight Loss, Asthma and COPD Drugs
Today (April 30, 2024), the U.S. Federal Trade Commission (FTC) announced that it had expanded its campaign against pharmaceutical manufacturers ’ improper or inaccurate listing of patents in the Food and Drug Administration ' s (FDA) Orange Book (see the news release athttps://www.ftc.gov/news-events/news/press-releases/2024/04/ftc-expands-patent-listing-challenges-targeting-more-300-junk-listings-diabetes-weight-loss-asthma for more information). FTC is targeting what it describes as more than 300 " junk " patent listings because the particular patents are legally ineligible to even be listed in the FDA Orange Book.Lis...
Source: Scott's Web Log - May 1, 2024 Category: Endocrinology Tags: 2024 FDA FTC improper listings Orange Book pharma Source Type: blogs

The TAME Trial for Metformin Remains Only Partially Funded
The Targeting Aging with Metformin (TAME) clinical trial has been a feature of the divide between regulators, researchers, and industry in the matter of treating aging as a medical condition for as about as long as the longevity industry has existed. Regulators such as the FDA do not consider aging to be a disease, and they only approve treatments for specific diseases, largely using the World Health Organization's International Classification of Diseases as the basis for what is and is not a disease. The TAME trial came into being as a way to convince the FDA to approve a treatment on the basis of endpoints that approxima...
Source: Fight Aging! - April 30, 2024 Category: Research Authors: Reason Tags: Longevity Industry Source Type: blogs

Lean Digital: How AI Drives Treatment Recommendations for Weight Loss
The first article in this series laid out what we know about body weight and obesity today. The rest of the Lean Digital series will look at some contributions that digital technologies are making toward solutions. The best contribution that information can make to weight management is to find more effective, personalized treatments: to match the right person to the right treatment, whether it be surgery, drugs, diet, exercise, or some combination. AI is turning up intriguing successes in this endeavor. I talked to Dr. Ronald Razmi, co-founder and managing director at Zoi Capital and author of the book AI Doctor: The Rise ...
Source: EMR and HIPAA - April 30, 2024 Category: Information Technology Authors: Andy Oram Tags: AI/Machine Learning Analytics/Big Data Clinical Communication and Patient Experience Genomics-Precision Medicine Health IT Company Healthcare IT Telemedicine and Remote Monitoring Andres Acosta apree health Behavior Management Behavi Source Type: blogs

What ’s behind all these assessments of digital health?
By MATTHEW HOLT A decent amount of time in recent weeks has been spent hashing out the conflict over data. Who can access it? Who can use it for what? What do the new AI tools and analytics capabilities allow us to do? Of course the idea is that this is all about using data to improve patient care. Anyone who is anybody, from John Halamka at the Mayo Clinic down to the two guys with a dog in a garage building clinical workflows on ChatGPT, thinks they can improve the patient experience and improve outcomes at lower cost using AI. But if we look at the recent changes to patient care, especially those brought on by dig...
Source: The Health Care Blog - April 29, 2024 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Health Tech Matthew Holt cost-effectiveness Diabetes digital health digital therapeutics Livongo MSK Peterson Health Technology Institute Source Type: blogs

Presence of Cardiometabolic Disease Correlates with Accelerated Brain Aging
It is well known that metabolic dysfunction and cardiovascular disease correlate well with an accelerated onset and progression of neurodegenerative conditions. This is particularly evident when considering these conditions in the context of obesity. Age-related diseases are the late stage consequences of a progressive accumulation of cell and tissue damage, and so a lifestyle that accelerates those underlying damage processes will produce a greater incidence of all of the common age-related diseases. Suffering from one form of age-related disease thus implies greater odds of suffering other forms of age-related disease, a...
Source: Fight Aging! - April 29, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Lean Digital: How Apps and Services Can Help Control Weight
Is anyone not obsessed with weight? The health care field certainly is. Researchers have found ties between high body weight and an oversized list of unhealthy conditions. Payers have invested enormous amounts of money in decreasing individuals’ body weights. A Congressional bill would promote behavioral therapy for obesity and extend Medicare coverage for drugs treating obesity. And yet weights continue to rise around the world, and the phenomenon starts at very young ages. The rapidly expanding use of GLP-1 drugs has been life-altering for many, but brings its own disappointments: They’re extremely expensive, req...
Source: EMR and HIPAA - April 29, 2024 Category: Information Technology Authors: Andy Oram Tags: AI/Machine Learning Analytics/Big Data Communication and Patient Experience Health IT Company Healthcare IT Telemedicine and Remote Monitoring Behavior Management Behavioral Change GLP-1 Healthcare Motivation Lean Digital Weight Loss S Source Type: blogs

A Progressive Failure of Glucose Regulation in the Aging Brain
There has long been a school of thought on Alzheimer's disease that consideres it a form of diabetes, in which dysregulated glucose metabolism features prominently. This dysregulation certainly occurs; the study noted here isn't the only one to show that the aging brain no longer manages glucose adequately. The question is whether this mechanism is important relative to all of the other processes thought to contribute to the pathology of Alzheimer's disease and other neurodegenerative conditions, and where it fits in a chain of cause and consequence. Finding ways to demonstrate the relative importance of different mechanis...
Source: Fight Aging! - April 29, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

A hypothetical case of medical malpractice. This can be you.  
A patient presents to the emergency room of a major local hospital with ulcers on the heels of both feet. The patient is more than 40 years old, smokes, and has hypertension but is not a diabetic. It is determined that the patient has peripheral artery disease. The patient is admitted to Dr. X’s service. Read more… A hypothetical case of medical malpractice. This can be you.  originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - April 28, 2024 Category: General Medicine Authors: Tags: Physician Malpractice Surgery Source Type: blogs