A High Level Popular Science View of the Longevity Industry
The article I'll point out today is an entirely unremarkable, high level tour of the most discussed, most notable portions of the longevity industry and related research efforts. Twenty years ago, we'd all have been delighted to see the media both noticing translational aging research at all, and then actually taking seriously the prospect of treating aging as a medical condition. We've come a long way to now see summary discussions of work on the treatment of aging as business as usual, not really worth mentioning. Still, articles like this miss near all of the really interesting projects, and that is the way of high leve...
Source: Fight Aging! - September 5, 2023 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs

Diabetes and liver disease: urgent screening needs highlighted by personal tragedy
The American Diabetes Association recently released screening guidelines for liver disease in individuals with type 2 diabetes. Notably, 70 percent of people with type 2 diabetes have liver disease, and the most common form is non-alcoholic fatty liver disease. Ultimately, this can lead to cirrhosis and cancer. According to the American Cancer Society, the rates Read moreā€¦ Diabetes and liver disease: urgent screening needs highlighted by personal tragedy originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - September 5, 2023 Category: General Medicine Authors: Tags: Conditions Diabetes Gastroenterology Source Type: blogs

Longer Life: 30-Minute Activity Reduces Common Disease Risk 20%
Thirty minutes per week of this activity lowers the risk of early death, diabetes, heart disease, and cancer. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - September 3, 2023 Category: Psychiatry & Psychology Authors: Mina Dean Tags: Exercise Source Type: blogs

A High-Fat Food That Reduces Blood Pressure
Two servings a day of this high-fat food could lower diabetes risk and reduce high blood pressure. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - September 2, 2023 Category: Psychiatry & Psychology Authors: Mina Dean Tags: Blood Pressure Diabetes Source Type: blogs

Podcast Episode Recommendation for Deconstructed: Medicare Drug Pricing Negotiations Advance
So, today I am going to share a podcast episode which provides an interesting history of how Medicare ended up being unable to negotiate prescription drug prices which, on its face, seems like it SHOULD make no sense, but somehow price negotiations never happened and the reasons were really absurd. Naturally, since the list of the first 10 drugs to get Medicare price negotiations was published, there has also been considerable discussion of insulin prices which is the poster-child for how broken the prescription drug market is, and even more interestingly was how, included in the first round of Medicare price negotiat...
Source: Scott's Web Log - September 1, 2023 Category: Endocrinology Tags: 2023 Biden Centers for Medicare & Medicaid Services Joe Biden Part D price negotiations Source Type: blogs

Diabetes Symptoms: An Early Warning Sign That Happens At Night
Correcting this disorder in diabetics would benefit them as well as many anti-diabetes drugs. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - September 1, 2023 Category: Psychiatry & Psychology Authors: Mina Dean Tags: Diabetes Source Type: blogs

How Technology Can Overcome Social Isolation
The previous article in introduced the topic of social isolation and showed its relationship to the subjective feeling of loneliness. Now we’ll start to look at the use of technology (which has been implicated in making these conditions worse) to try to improve them. Physically Connecting Lonely Individuals mPulse Mobile evaluates patient needs and suggests local resources they can tap, including peer groups. The service gets data from patient records through AI and natural language processing (NLP). as well as from what the patient says to the service. According to Eden Brownell, director of behavioral science, mP...
Source: EMR and HIPAA - August 30, 2023 Category: Information Technology Authors: Andy Oram Tags: Analytics/Big Data Clinical Health IT Company Healthcare IT LTPAC Aging in Place Andy Tubman Avanade Caretakers Christiana Voelker Dr. Kate Burke Eden Brownell HealCommunity Healthcare AI Healthcare NLP James Maskell loneli Source Type: blogs

Who moved the goalposts?
Welcome to another episode of BDI Briefs! Our aim with BDI Briefs is to take a brief look at important issues about the emotional side of diabetes.In this short discussion, Scott, Bill, and Susan ask whether striving for better-than-standards diabetes management is worthwhile. Or could there be unintended consequences? Detailed show notes and transcript Scott Johnson:Welcome to BDI Briefs. This is another exciting installment where we take a brief look at important issues about the emo...
Source: Scott's Diabetes Blog - August 28, 2023 Category: Endocrinology Authors: Scott K. Johnson Tags: Blog Posts Source Type: blogs

Who moved the goalposts?
Welcome to another episode of BDI Briefs! Our aim with BDI Briefs is to take a brief look at important issues about the emotional side of diabetes. In this short discussion, Scott, Bill, and Susan ask whether striving for better-than-standards diabetes management is really worthwhile? Or could it have unintended consequences? (Source: Scott's Diabetes Blog)
Source: Scott's Diabetes Blog - August 28, 2023 Category: Endocrinology Authors: Scott K. Johnson Tags: Blog Posts Source Type: blogs

Fight Aging! Newsletter, August 28th 2023
In conclusion, we identified 20 genes with significant evolutionary signals unique to long-lived species, which provided new insight into the lifespan extension of mammals and might bring new strategies to extend human lifespan. « Back to Top Trials of Xenotransplantation of Pig Organs into Humans Continue https://www.fightaging.org/archives/2023/08/trials-of-xenotransplantation-of-pig-organs-into-humans-continue/ Researchers have genetically engineered pigs to overcome the known barriers to transplantation of pig organs into humans, and have reached the stage of conducting transplants i...
Source: Fight Aging! - August 27, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

The Longevity-Associated Variant of BPIFB4 Reduces Heart Disease Severity
Few human longevity-associated gene variants are replicated in multiple patient populations. One of those is a variant of BPIFB4, that appears to improve immune function and lower inflammation by adjusting the behavior of macrophage cells of the innate immune system. Delivering the variant to mice using a gene therapy has similar effects. It may well operate via other mechanisms as well, however. Few proteins in a living cell turn out to have only one purpose. In today's open access paper, researchers report that the BPIFB4 variant reduces the severity of coronary artery disease in humans and mice. Delivering the va...
Source: Fight Aging! - August 25, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Insurance Deductibles Don't Work Well for Patients with Chronic Illnesses. Some strategies for PWD's With HDHP's to Consider.
The U.S. IRS defines a High-Deductible Health Plan (HDHP) as a health plan with an annual deductible that is not less than $1,500 for self-only coverage or $3,000 for family coverage, and for which the annual out-of-pocket expenses (deductibles, co-payments, and other amounts). About half of all Americans with employer-sponsored healthcare insurance plans have deductibles to satisfy before the insurance covers much although some employers provide Health Reimbursement Accounts (HRAs) to help offset the deductible. That said, the IRS has also ruled that an HDHP can cover certain types of " preventive " care without a deducti...
Source: Scott's Web Log - August 24, 2023 Category: Endocrinology Tags: 2023 Ascensia CGM E3 Eversense HDHP Senseonics Source Type: blogs

Lipid Metabolism in Age-Related Disease
In this age of excess calories, in which a large proportion of the population is significantly overweight, research into lipid metabolism in the context of aging tends overlap with research into lipid metabolism in the context of obesity. People of normal weight still undergo complex changes in lipid metabolism and lipid transport throughout the body with age, however. These lead to prominent, important issues such as atherosclerosis, localized excesses of cholesterol and associated lesions in the arterial walls, for example. Looking at these conditions through the lens of lipid metabolism is looking at just one part of a ...
Source: Fight Aging! - August 23, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Why Amazon Pharmacy's Recent Insulin Move is Helpful, But Not Groundbreaking
On August 15, 2023, Amazon Pharmacy (fka PillPack) announced (seehttps://www.aboutamazon.com/news/retail/amazon-pharmacy-insulin-coupons/ for the announcement) that it would begin automatically applying various manufacturer coupons to more than 15 common insulins and diabetes devices (including Dexcom, which offers a coupon for up to $200 per month athttps://www.dexcom.com/en-us/savings-center-cgm-without-insurance/ even without insurance). So far, no coupons from Abbott on Freestyle Libre 3 sensors, but the longer wear-time of 14-days means those cost about one-third less than Dexcom ' s 10-day Some products, such as bloo...
Source: Scott's Web Log - August 22, 2023 Category: Endocrinology Tags: 2023 Amazon Amazon Pharmacy coupons insulin prices Source Type: blogs

The Diet That Starts Reversing Diabetes In Only 7 Days
Patients with diabetes could lose 15 kg and beat the condition as long as follow this path. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - August 22, 2023 Category: Psychiatry & Psychology Authors: Mina Dean Tags: Diabetes Source Type: blogs