The association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio with type 2 diabetes mellitus: recent findings from NHANES 2007 –2018
This study aims to assess the relationship between NHHR (non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio) and Type 2 diabetes mellitus (T2DM) in US adults, using National... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - May 21, 2024 Category: Lipidology Authors: Mo-Yao Tan, Li Weng, Zhong-Hao Yang, Si-Xuan Zhu, Shan Wu and Jun-Hua Su Tags: Research Source Type: research
Anamorelin for the Treatment of Cancer Anorexia-Cachexia Syndrome
AbstractPurpose of ReviewThe following review will highlight the development of anamorelin to treat cancer anorexia-cachexia syndrome (CACS) including the potential benefits, limitations, and future directions.Recent FindingsGhrelin, a 28-amino acid peptide hormone, is secreted by the stomach mucosa and regulates appetite, promotes lipogenesis, increases body weight, improves gastric motility, reduces catabolic wasting and inflammation. Several randomized, double-blind, placebo-controlled clinical trials evaluating anamorelin, a ghrelin agonist, for the treatment of CACS have reported improvement in appetite and body compo...
Source: Current Oncology Reports - May 21, 2024 Category: Cancer & Oncology Source Type: research
The Efficacy and Safety of Sodium-Glucose Co-transporter 2 (SGLT2) Inhibitors in Real-World Clinical Practice: Potential Cautionary Use in Elderly Patients with Type 2 Diabetes (T2D)
ConclusionsIn this study, we demonstrated that SGLT2 inhibitors are an effective and durable hypoglycemic agent to control blood glucose levels with reduced maintenance of Bwt, but their use in the elderly ( ≥ 75 years old) patients with T2D may warrant some additional caution due to increased probability of AEs and discontinuation of drug use. (Source: Diabetes Therapy)
Source: Diabetes Therapy - May 21, 2024 Category: Endocrinology Source Type: research
Urban –Rural Differences in the Prevalence of Diabetes Among Adults in Haryana, India: The ICMR-INDIAB Study (ICMR-INDIAB-18)
ConclusionsThe current analysis provides robust prevalence estimates highlighting the urban –rural disparities. Urban areas continue to have a high prevalence of diabetes and prediabetes; rural areas depict a much higher prevalence of prediabetes than diabetes. With the economic transition rapidly bridging the gap between urban and rural populations, health policymakers should plan effic ient strategies to tackle the diabetes epidemic. (Source: Diabetes Therapy)
Source: Diabetes Therapy - May 21, 2024 Category: Endocrinology Source Type: research
Prediction of retinopathy progression using deep learning on retinal images within the Scottish screening programme
Conclusions
We showed that, compared with using the current retinopathy grade, DL of fundus images significantly improves the prediction of incident referable retinopathy before the next screening episode. This can impact screening recall interval policy positively, for example, by reducing the expected time with referable disease for a fixed workload—which we show as an exemplar. Additionally, it could be used to optimise workload for a fixed sojourn time. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - May 21, 2024 Category: Opthalmology Authors: Mellor, J., Jiang, W., Fleming, A., McGurnaghan, S. J., Blackbourn, L. A. K., Styles, C., Storkey, A., McKeigue, P. M., Colhoun, H. M. Tags: Retina Source Type: research
Feasibility and acceptance of artificial intelligence-based diabetic retinopathy screening in Rwanda
Conclusion
DR screening using AI led to accurate referrals from diabetes clinics in Rwanda and high rates of participant satisfaction, suggesting AI screening for DR is practical and acceptable. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - May 21, 2024 Category: Opthalmology Authors: Whitestone, N., Nkurikiye, J., Patnaik, J. L., Jaccard, N., Lanouette, G., Cherwek, D. H., Congdon, N., Mathenge, W. Tags: Retina Source Type: research
Long-term risk of overweight in offspring of Chinese women with gestational diabetes defined by IADPSG's but not by WHO's criteria
To examine long-term risk of overweight in offspring of women with gestational diabetes mellitus (GDM) defined by the International Association of Diabetes and Pregnancy Study Group (IADPSG)'s criteria but not by the 1999 World Health Organization (WHO)'s criteria. (Source: Primary Care Diabetes)
Source: Primary Care Diabetes - May 21, 2024 Category: Primary Care Authors: Weihan Cao, Hui Wang, Shumin Zhao, Jin Liu, Enqing Liu, Tao Zhang, Ninghua Li, Ming Gao, Jing Li, Zhijie Yu, Gang Hu, Junhong Leng, Xilin Yang Source Type: research
Impact of Recurrent Weight Gain Thresholds on Comorbid Conditions Progression Following Laparoscopic Sleeve Gastrectomy
ConclusionRecurrent weight gain ≥ 20% of maximum weight loss can be treated as a specific threshold indicating comorbidity progression post-LSG. Standardizing the measurement of recurrent weight gain can help healthcare providers to implement targeted management strategies to optimize long-term health outcomes. (Source: Obesity Surgery)
Source: Obesity Surgery - May 21, 2024 Category: Surgery Source Type: research
Single-Port One Anastomosis Sleeve Gastrectomy with Transit Bipartition: Initial Experience and Technique
ConclusionIn our small cases of patients, single-port SG-OATB is feasible and safe. We found the closure of the anastomosis defect to be most technically demanding. To understand better the outcome of single-port SG-OATB, studies with larger sample and longer follow-up will be needed in the future. (Source: Obesity Surgery)
Source: Obesity Surgery - May 21, 2024 Category: Surgery Source Type: research
Visual function after ultrathin Descemets stripping automated endothelial keratoplasty or Descemets membrane endothelial keratoplasty combined with cataract surgery: a randomised controlled clinical trial
Conclusions
Compared with UT-DSAEK, DMEK resulted in better BCVA 3, 6 and 12 months postoperatively. Twelve months postoperatively, DMEK had a higher ECD than UT-DSAEK; however, no difference in contrast sensitivity was found.
Trial registration number
NCT04417959 (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - May 21, 2024 Category: Opthalmology Authors: Madsen, M. B. M., Ivarsen, A., Hjortdal, J. Tags: Cornea and ocular surface Source Type: research
Autonomous screening for laser photocoagulation in fundus images using deep learning
Conclusion
The proposed model for laser treatment detection achieved high performance on all analysis metrics and has been demonstrated to positively affect the efficacy of different AI models, suggesting that laser detection can generally improve AI-powered applications for fundus images. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - May 21, 2024 Category: Opthalmology Authors: Bressler, I., Aviv, R., Margalit, D., Rom, Y., Ianchulev, T., Dvey-Aharon, Z. Tags: Open access Retina Source Type: research
The effects of ketogenic diet on metabolic and hormonal parameters in patients with polycystic ovary syndrome: a systematic review and meta-analysis of clinical trials
ConclusionThe KD demonstrated promising outcomes in improving metabolic and hormonal parameters in women diagnosed with PCOS. (Source: Journal of Diabetes and Metabolic Disorders)
Source: Journal of Diabetes and Metabolic Disorders - May 21, 2024 Category: Endocrinology Source Type: research
Telemedicine home-based management in patients with chronic heart failure and diabetes type II: study protocol for a randomized controlled trial
Heart failure and type 2 diabetes are prevalent public health issues in Europe. These complex chronic conditions require extensive pharmacological management, ongoing self-care, and behavioral changes. Despite... (Source: Trials)
Source: Trials - May 21, 2024 Category: General Medicine Authors: Palmira Bernocchi, Vittorio Giudici, Gabriella Borghi, Patrizia Bertolaia, Salvatore D ’Isa, Roberto Trevisan and Simonetta Scalvini Tags: Study protocol Source Type: research
Implementation research: a protocol for two three-arm pragmatic randomised controlled trials on continuous glucose monitoring devices in people with type 1 diabetes in South Africa and Kenya
Self-monitoring of glucose is an essential component of type 1 diabetes (T1D) management. In recent years, continuous glucose monitoring (CGM) has provided an alternative to daily fingerstick testing for the o... (Source: Trials)
Source: Trials - May 21, 2024 Category: General Medicine Authors: Elena Marb án-Castro, Lorrein Muhwava, Yvonne Kamau, Elvis Safary, Paul Rheeder, Maria Karsas, Tanja Kemp, Johanè Freitas, Michelle Carrihill, Joel Dave, Daniel Katambo, Joan Kimetto, Razana Allie, Joseph Ndungu, Ntombi Sigwebela, Dorcas Akach & hellip; Tags: Study protocol Source Type: research
Association of gastrointestinal microbiome and obesity with gestational diabetes mellitus-an updated globally based review of the high-quality literatures
Nutrition & Diabetes, Published online: 21 May 2024; doi:10.1038/s41387-024-00291-5Association of gastrointestinal microbiome and obesity with gestational diabetes mellitus-an updated globally based review of the high-quality literatures (Source: Nutrition and Diabetes)
Source: Nutrition and Diabetes - May 21, 2024 Category: Nutrition Authors: Jiahui Li Min Wang Shuai Ma Zhong Jin Haonan Yin Shuli Yang Source Type: research
