Dietary Modulations in Preventing Cardiometabolic Risk in Individuals with Type 2 Diabetes
AbstractPurpose of ReviewType 2 diabetes mellitus (T2DM) is a complex health issue include obesity, high cholesterol, high blood pressure, and chronic inflammation that increase the risk of cardiovascular diseases (CVDs). CVDs are of great concern in the disease progression and prognosis of T2DM. This review is a comprehensive examination of the literature on the relationship between T2DM and cardiovascular risk, nutrition-related cardiometabolic risk (CMR) factors, and impact of dietary modulations on CMR.Recent FindingsIn recent years the researches has been focus on the importance of a comprehensive treatment approach l...
Source: Current Nutrition Reports - May 20, 2024 Category: Nutrition Source Type: research
Hypopituitarism with secondary adrenocortical insufficiency and arginine vasopressin deficiency due to hypophysitis after COVID-19 vaccination: a case report
Although vaccination against coronavirus disease (COVID-19) has several side effects, hypopituitarism due to hypophysitis has rarely been reported. (Source: BMC Endocrine Disorders)
Source: BMC Endocrine Disorders - May 20, 2024 Category: Endocrinology Authors: So Watanabe, Yoshiaki Tamura, Kazuhito Oba, Saori Kitayama, Motoya Sato, Remi Kodera, Kenji Toyoshima, Yuko Chiba and Atsushi Araki Tags: Case Report Source Type: research
Management of low-risk papillary thyroid cancer. Minimally-invasive treatments dictate a further paradigm shift?
ConclusionsMITs represent a promising non-surgical option for managing low-risk PTMC, especially for patients ineligible for or refusing surgery. Despite favorable outcomes, more robust prospective data are needed to confirm their long-term benefits and completeness of tumor ablation. Interdisciplinary discussions and thorough patient education on the advantages and limitations of MITs are crucial for informed decision-making. (Source: Endocrine)
Source: Endocrine - May 20, 2024 Category: Endocrinology Source Type: research
Multi-element analysis of metals in human pathological and unchanged thyroid glands – pilot study
AbstractDisturbances in the homeostasis of the elemental composition of thyroid tissue may have serious metabolic and health consequences. It is believed that the accumulation of some metals or the deficiency of others may even cause lethal tumours. Due to the fact that metallomics most often uses human serum to analyse macro and microelements as well as trace elements, it was decided to use material that is more difficult to obtain, but also adds credibility to the research – thyroid tissue samples biopsy. The experiments were conducted on 17 patients diagnosed with: nodular (10) and colloidal goitre (2), chronic thyroi...
Source: Thyroid Research - May 20, 2024 Category: Endocrinology Source Type: research
Bile acid receptor protects against diabetic cardiomyopathy
Nature Reviews Cardiology, Published online: 20 May 2024; doi:10.1038/s41569-024-01040-yActivation of the bile acid receptor TGR5 inhibits CD36-mediated fatty acid uptake in cardiomyocytes and protects against cardiac lipotoxicity and the development of diabetic cardiomyopathy in mice, according to a new study. (Source: Nature Reviews Cardiology)
Source: Nature Reviews Cardiology - May 20, 2024 Category: Cardiology Authors: Irene Fern ández-Ruiz Source Type: research
Transcriptional control of metabolism by interferon regulatory factors
Nature Reviews Endocrinology, Published online: 20 May 2024; doi:10.1038/s41574-024-00990-0Interferon regulatory factors (IRFs) are well known as mediators of the antiviral response but there is growing appreciation of their role in metabolism. This Review discusses the current understanding of IRFs as metabolic regulators, with a particular focus on IRF3 and IRF4. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - May 20, 2024 Category: Endocrinology Authors: Zunair Ahmad Wahab Kahloan Evan D. Rosen Source Type: research
HbA1c changes in a deprived population who followed or not a diabetes self-management programme, organised in a multi-professional primary care practice: a historical cohort study on 207 patients between 2017 and 2019
Diabetes self-management (DSM) helps people with diabetes to become actors in their disease. Deprived populations are particularly affected by diabetes and are less likely to have access to these programmes. D... (Source: BMC Endocrine Disorders)
Source: BMC Endocrine Disorders - May 20, 2024 Category: Endocrinology Authors: Sarah Ajrouche, Lisa Louis, Maxime Esvan, Anthony Chapron, Ronan Garlantezec and Emmanuel Allory Tags: Research Source Type: research
Socio-behavioral determinants of health-related quality of life among patients with type 2 diabetes: comparison between 2015 and 2018
Type 2 diabetes (T2D) is a common chronic disease that significantly affects an individual ’s overall health and well-being. The aim of this study is to investigate the factors that influence the health-related... (Source: BMC Endocrine Disorders)
Source: BMC Endocrine Disorders - May 20, 2024 Category: Endocrinology Authors: Neda Izadi, Arman Shafiee, Mahdieh Niknam, Reza Yari-Boroujeni, Fereidoun Azizi and Parisa Amiri Tags: Research Source Type: research
Assessment of genetic and clinical factors in T2D susceptibility among patients with hypertension
ConclusionIncorporating clinical and genetic screening into risk assessment is important for the detection and prevention of T2D in patients with HTN. The detected SNPs (rs7865889, rs12737517, and rs10896290), especially the protective SNP (rs12737517), provide an opportunity for better diagnosis, prevention, and therapy of patients with T2D and HTN. (Source: Acta Diabetologica)
Source: Acta Diabetologica - May 20, 2024 Category: Endocrinology Source Type: research
Tirzepatide 5, 10 and 15 mg versus injectable semaglutide 0.5 mg for the treatment of type 2 diabetes: An adjusted indirect treatment comparison
To compare the efficacy and safety of tirzepatide 5, 10 and 15 mg with subcutaneous semaglutide 0.5 mg as second-line treatment for adults with type 2 diabetes mellitus, after metformin monotherapy, using adjusted indirect treatment comparisons (aITCs). (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - May 20, 2024 Category: Endocrinology Authors: Beatrice Osumili, Ludi Fan, Jim S. Paik, Kevin M. Pantalone, Kari Ranta, H élène Sapin, Santiago Tofé Source Type: research
Open questions on basal insulin therapy in T2D: a Delphi consensus
ConclusionIn a continuously evolving scenario, BI therapy still represents an important option in the management of T2D patients. (Source: Acta Diabetologica)
Source: Acta Diabetologica - May 20, 2024 Category: Endocrinology Source Type: research
An invited commentary on: “Causal relationship between gestational diabetes and preeclampsia: A bidirectional mendelian randomization analysis”
In response to recent feedback and concerns raised regarding our study utilizing data from the FinnGen database, we would like to extend our sincerest apologies for any oversights and assure our commitment to rectifying these issues promptly. This commentary aims to transparently address the concerns raised, outline the steps taken to rectify them, and emphasize our dedication to upholding the highest standards of scientific integrity in genetic epidemiology research. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - May 20, 2024 Category: Endocrinology Authors: Xiaofeng Yang, Lan Wang Tags: Commentary Source Type: research
Impact of empagliflozin on first and recurrent events leading to or prolonging hospitalisation in the EMPA-REG OUTCOME trial
In EMPA-REG OUTCOME, empagliflozin reduced the composite of total events leading to/prolonging hospitalisation for any cause and all-cause mortality by 24 % versus placebo in patients with T2DM and ASCVD, with 67.7 events prevented/1000 patient-years and a low NNT. Effects were sustained and were consistent regardless of the reason for hospitalisation. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - May 20, 2024 Category: Endocrinology Authors: Silvio E. Inzucchi, Christoph Wanner, David Fitchett, Bernard Zinman, Stefan D. Anker, Stuart J. Pocock, Michaela Mattheus, Stefan Hantel, S øren S. Lund Tags: Brief Report Source Type: research
Type 2 diabetes in latin America: recommendations on the flash glucose monitoring system
To establish recommendations through the consensus of a Latin American experts panel on the use of the flash glucose monitoring system (fCGM) in people living with type 2 diabetes mellitus (T2DM) regarding the... (Source: Diabetology and Metabolic Syndrome)
Source: Diabetology and Metabolic Syndrome - May 20, 2024 Category: Endocrinology Authors: Marcio Krakauer, Ana M. G ómez, Paloma Almeda-Valdes, Helard Manrique, María Lidia Ruiz Morosini, Gonzalo Godoy Jorquera, João Eduardo Nunes Salles, David Sanhueza Costa, Rodrigo de Azeredo Siqueira, Raquel N. Faradji, Alex Rincón Ramírez, Matías R Tags: Research Source Type: research
Nonalcoholic Fatty Liver Disease and Ethnicity: Lessons Learned from the Arab Population in Israel
AbstractNon-alcoholic fatty liver disease (NAFLD) is the most common liver disease. We aimed to investigate the potential similarities and differences regarding the disease among Arabs and Jews. Retrospective study included all patients older than 18 years with NAFLD diagnosis according to ICD-10 codes. Data regarding demographics, comorbidities, and outcomes were retrieved using the MdClone platform from “Clalit” in Israel. Data concerning 34,090 Arab patients and 173,500 Jewish patients with NAFLD were included. Arab patients were significantly younger at diagnosis (35.0 ± 13 years vs. 43.6 ± 15 years,p &...
Source: Journal of Immigrant and Minority Health - May 20, 2024 Category: International Medicine & Public Health Source Type: research
