GALNT2 expression is associated with glucose control and serum metabolites in patients with type 2 diabetes
ConclusionsOur data indicate that in type 2 diabetes the expression ofGALNT2 is associated with several serum metabolites. This association needs to be further investigated to understand in depth its role in mediating the effect of GALNT2 on insulin sensitivity, glucose control and other clinical features in people with diabetes. (Source: Acta Diabetologica)
Source: Acta Diabetologica - April 17, 2024 Category: Endocrinology Source Type: research

Correlation between omega-3 intake and the incidence of diabetic retinopathy based on NHANES from 2005 to 2008
ConclusionsIn this cross-sectional study of the U.S. general population, we found that increased intake of omega-3 and its components, specifically DPA and DHA were negatively associated with DR incidence. This suggests that omega-3 may be a potential protective factor for DR and may help to prevent or delay the onset and progression of DR. (Source: Acta Diabetologica)
Source: Acta Diabetologica - April 16, 2024 Category: Endocrinology Source Type: research

Correction to: High remnant cholesterol as a risk factor for developing chronic kidney disease in patients with prediabetes and type 2 diabetes: a cross-sectional study of a US population
(Source: Acta Diabetologica)
Source: Acta Diabetologica - April 16, 2024 Category: Endocrinology Source Type: research

Maintaining a gluten-free diet is associated with quality of life in youths with type 1 diabetes and celiac disease
ConclusionThe coexistence of T1D and CD and the adoption of a GFD resulted in poor QoL levels, as in youth as in their parents, when difficulties implementing the GFD are present. Psychological support should consider the importance of maintaining GFD not only to prevent potential complications in the future but also to improve actual QoL in different subdomains. (Source: Acta Diabetologica)
Source: Acta Diabetologica - April 13, 2024 Category: Endocrinology Source Type: research

Anti-adipogenesis effect of indole-3-acrylic acid on human preadipocytes and HFD-induced zebrafish
ConclusionsTaken together, IA has been identified as a potent metabolite for the prevention or treatment of obesity.Graphic Abstract (Source: Acta Diabetologica)
Source: Acta Diabetologica - April 10, 2024 Category: Endocrinology Source Type: research

Associations between life ’s essential 8 and metabolic health among us adults: insights of NHANES from 2005 to 2018
ConclusionsHigher LE8 and its subscales scores were inversely and nonlinearly linked with the lower presence of MUH. MUH is consistent with LE8 scores, which can be considered as an alternative indicator when it is difficult to collect the information of health behaviors. (Source: Acta Diabetologica)
Source: Acta Diabetologica - April 7, 2024 Category: Endocrinology Source Type: research

Impaired erythropoietin response to hypoxia in type 2 diabetes
ConclusionsThese findings suggest an impaired erythropoietin response to decreased oxygen levels in patients with type 2 diabetes, which may contribute to the reduced oxygen transport capacity observed in this population. (Source: Acta Diabetologica)
Source: Acta Diabetologica - April 4, 2024 Category: Endocrinology Source Type: research

Comparison of the optical coherence tomography-angiography (OCT-A) vascular measurements between molecularly confirmed MODY and age-matched healthy controls
ConclusionThe significant CC-VD increase in the MODY group might be associated with hyperglycemia and/or relatively poor and vulnerable peripheral vascular CC perfusion compared to the central. Previous thickness and VD results of childhood or adolescent diabetes were distributed in a wider range, suggesting that various factors, including some not yet clearly defined, may affect the choroidal vasculature independently of glycemia or as a contributing factor. (Source: Acta Diabetologica)
Source: Acta Diabetologica - April 2, 2024 Category: Endocrinology Source Type: research

Correction to: Development of the Italian clinical practice guidelines for the treatment of diabetic foot syndrome: design and methodological aspects
(Source: Acta Diabetologica)
Source: Acta Diabetologica - April 2, 2024 Category: Endocrinology Source Type: research

Reply to comment on: Association of glucose-lowering drugs with incident stroke and transient ischaemic attacks in primary care patients with type 2 diabetes: disease analyser database
(Source: Acta Diabetologica)
Source: Acta Diabetologica - April 2, 2024 Category: Endocrinology Source Type: research

Prostanoids in patients with diabetes and chronic limb-threatening ischemia: a meta-analysis of randomized clinical trials for the development of the Italian guidelines for the treatment of diabetic foot syndrome
(Source: Acta Diabetologica)
Source: Acta Diabetologica - April 2, 2024 Category: Endocrinology Source Type: research

Association of visceral adipose tissue with albuminuria and interaction between visceral adiposity and diabetes on albuminuria
ConclusionsHigh VFA may represent an independent risk factor for albuminuria. The amount of visceral fat may affect the effect of diabetes on albuminuria. The higher the visceral fat, the stronger the correlation between diabetes and albuminuria should be present. We suppose an additive interaction between VFA and diabetes on the effect of albuminuria. (Source: Acta Diabetologica)
Source: Acta Diabetologica - April 1, 2024 Category: Endocrinology Source Type: research

The association of islet autoantibodies with the neural retinal thickness and microcirculation in type 1 diabetes mellitus with no clinical evidence of diabetic retinopathy
ConclusionsIAbs are associated with neural retinal thinning and microcirculation reduction in T1DM patients before the clinical onset of diabetic retinopathy. (Source: Acta Diabetologica)
Source: Acta Diabetologica - March 26, 2024 Category: Endocrinology Source Type: research

Self-supervised category selective attention classifier network for diabetic macular edema classification
ConclusionsThe proposed SSCSAC-Net represents a significant advancement in automated DME classification. By effectively using self-supervised learning and attention mechanisms, the model offers improved accuracy in identifying DME-related features within retinal images. Its robustness and generalizability across different datasets highlight its potential for clinical applications, providing a valuable tool for clinicians in diagnosing DME effectively. (Source: Acta Diabetologica)
Source: Acta Diabetologica - March 23, 2024 Category: Endocrinology Source Type: research

Associations of muscle mass and strength with new-onset diabetes among middle-aged and older adults: evidence from the China health and retirement longitudinal study (CHARLS)
ConclusionsLower muscle strength is associated with  an increased risk of diabetes, especially in obese populations. (Source: Acta Diabetologica)
Source: Acta Diabetologica - March 20, 2024 Category: Endocrinology Source Type: research