Disparities in prevalence and treatment of diabetes, cardiovascular and chronic kidney diseases – Recommendations from the taskforce of the guideline workshop
There is a mounting clinical, psychosocial, and socioeconomic burden worldwide as the prevalence of diabetes, cardiovascular disease (CVD), and chronic kidney disease (CKD) continues to rise. Despite the introduction of therapeutic interventions with demonstrated efficacy to prevent the development or progression of these common chronic diseases, many individuals have limited access to these innovations due to their race/ethnicity, and/or socioeconomic status (SES). However, practical guidance to providers and healthcare systems for addressing these disparities is often lacking. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - April 11, 2024 Category: Endocrinology Authors: James R. Gavin, Helena W. Rodbard, Tadej Battelino, Frank Brosius, Antonio Ceriello, Francesco Cosentino, Francesco Giorgino, Jennifer Green, Linong Ji, Monika Kellerer, Susan Koob, Mikhail Kosiborod, Nebojsa Lalic, Nikolaus Marx, T. Prashant Nedungadi, C Tags: Commentary Source Type: research

One abnormal value in oral glucose tolerance test during pregnancy and type 2 diabetes risk: Insights from a 5-Year Follow-Up study
To evaluate the risk of type 2 diabetes(T2D) following one abnormal value(OAbV) in an oral glucose tolerance test(oGTT) performed during pregnancy. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - April 10, 2024 Category: Endocrinology Authors: Rawia Hussein-Aro, Esther Maor-Sagie, Yoel Toledano, Mordechai Hallak, Rinat Gabbay-Benziv Source Type: research

Circulating immune cell phenotyping is potentially relevant for diabetic retinopathy risk assessment
Inflammation is believed to play a central role in the development of diabetes mellitus and is a common feature of type 2 diabetes mellitus (T2DM). However, the association with diabetic retinopathy (DR) remains a topic of debate. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - April 10, 2024 Category: Endocrinology Authors: Bo Li, Xu Zhao, Zhenzhen Hong, Yan Ding, Yi Zhang Source Type: research

Verification of 2021 IDF-DAR risk assessment tool for fasting Ramadan in patients with diabetes attending primary health care in The Kingdom of Bahrain: The DAR-BAH study
There is a high prevalence of diabetes mellitus among Muslim adult patients. Those Muslims are required to fast the holy month of Ramadan. However, the Islam religion exempted some people with medical issues. It was not clear if all the patients with diabetes were considered medically unfit to fast Ramadan. Therefore, IDF-DAR group created a new risk calculator to categorize the patients with diabetes to advise with or against fasting accordingly. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - April 9, 2024 Category: Endocrinology Authors: Najla Shamsi, Jameel Naser, Hanan Humaidan, Abeer Al-Saweer, Masooma Jaafar, Fadheela Abbas, Sumaya Al-Doseri, Najat Shabeeb, Ebtihaj Al-Shaikh, AbdulRasool Al-Dairi, Khawla Mandoos Source Type: research

Liver and cardiovascular disease outcomes in metabolic syndrome and diabetic populations: Bi-directional opportunities to multiply preventive strategies
The incidence and prevalence of metabolic syndrome (MetS) and type 2 diabetes mellitus (T2DM) are rising globally. MetS and T2DM are associated with significant morbidity and mortality, which is partly related to liver and cardiovascular disease. Insulin resistance is central to MetS and T2DM pathophysiology, and drives ectopic fat deposition in the liver, also known as metabolic dysfunction-associated steatotic liver disease (MASLD). MetS and T2DM are not only risk factors for developing MASLD but are also independently associated with disease progression to steatohepatitis, cirrhosis, and hepatocellular carcinoma. (Sourc...
Source: Diabetes Research and Clinical Practice - April 9, 2024 Category: Endocrinology Authors: Alhussain Yasin, Madison Nguyen, Angad Sidhu, Priyanka Majety, Jared Spitz, Amon Asgharpour, Mohammad S. Siddiqui, Laurence S. Sperling, Arshed A. Quyyumi, Anurag Mehta Source Type: research

Associations between diabetes and cancer: A 10-year national population-based retrospective cohort study
There are many similarities between the risk factors of diabetes and cancer, this alone does not seem to explain the coexistence of the two diseases. Several studies have shown that diabetes is an independent risk factor for multiple cancer sites [1 –3]. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - April 9, 2024 Category: Endocrinology Authors: Hel éna Safadi, Ágnes Balogh, Judit Lám, Attila Nagy, Éva Belicza Source Type: research

Newly detected diabetes mellitus patients with acute coronary syndrome have an adverse cardiometabolic profile similar to patients with prior diabetes and a more extensive ischemic myocardial insult
Diabetes mellitus (DM) prevalence is approximately 9  % worldwide and more that 600 million people would be affected in 2040[1]. The presence of DM doubles the risk of coronary artery disease (CAD) development[2]. In a recent analysis from the Atherosclerosis Risk in Communities (ARIC) study, it was found that 40 % of acute coronary syndrome (ACS) patients also suffer from DM, have multiple comorbidities and not infrequently receive suboptimal therapy, such as antiplatelet agents and coronary revascularization[3]. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - April 8, 2024 Category: Endocrinology Authors: Loukianos S Rallidis, Konstantinos A Papathanasiou, Donatos Tsamoulis, Vasileios Bouratzis, Ioannis Leventis, Charalampos Kalantzis, Belkis Malkots, Petros Kalogeras, Dimitrios Tasoulas, Iosif Delakis, Apostolos Lykoudis, Stylianos Daios, Victoria Potoupn Source Type: research

Cardiovascular risk reduction in older people with type 2 diabetes mellitus-a comprehensive narrative review
Metabolic targets are controversial in older people with type 2 diabetes due to functional heterogeneity and morbidity burden. Tight blood pressure and metabolic control appears beneficial in fit individuals who are newly diagnosed with type 2 diabetes and have fewer comorbidities. The benefits of low blood pressure and tight metabolic control is attenuated with the development of comorbidities, especially frailty. Guidelines consider frail older people as one category and recommend relaxed targets. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - April 8, 2024 Category: Endocrinology Authors: Pann Ei Hnynn Si, S. Parker, D. Abdelhafiz, A. Summerbell, S. Muzulu, Ahmed H. Abdelhafiz Source Type: research

Do WHO criteria for gestational diabetes fit a rural population in Tanzania? – A follow-up study assessing mother and child health six years after a pregnancy diagnosed with gestational diabetes
The burden of diabetes across the world has reached epidemic proportions affecting nearly one in every ten adults [1]. The strongest predictor for developing diabetes is overweight caused by an inactive lifestyle and overnutrition, followed by genetic disposition, advanced age, prediabetes, and for women especially a pregnancy complicated by gestational diabetes mellitus (GDM) [2]. Low- and middle-income countries (LMICs) account for around 80  % of the worldwide prevalence of diabetes, putting pressure on already overburdened health systems [1]. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - April 5, 2024 Category: Endocrinology Authors: Camilla Byskou Eriksen, Daniel Thomas Minja, Dirk Lund Christensen, Ib Christian Bygbjerg, Peter Damm, Christentze Schmiegelow, Louise Groth Grunnet, Line Hjort Source Type: research

The use of potentially interacting supplement –drug pairs in adults with type 2 diabetes: A large population-based cohort study in the UK Biobank
To examine the patterns of use of potentially interacting supplement –drug pairs in adults with type 2 diabetes (T2D) in real-world settings, and to explore the impact of potentially interacting supplement–drug pairs on downstream outcomes. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - April 5, 2024 Category: Endocrinology Authors: Rong Hua, Chun Sing Lam, Yu Kang Wu, Weishang Deng, Natural Chu, Aimin Yang, Elaine Chow, Yin Ting Cheung Source Type: research

Insulin icodec use in hospital settings: Considerations for once-weekly basal insulin therapy in hospital glycaemic management practice
Diabetes management has benefitted greatly from novel insulin analogues with action profiles that better match individual ’s requirements. However, the increased complexity of hospital insulin administration involving multiple practitioners, rapidly changing clinical situations, and therapies causing hyperglycaemia, demands specific consideration for their use. Insulin icodec has an extended duration of action and is beginning to be used in the ambulatory setting. A reassuring early trial experience observed no substantial dysglycaemia in 135 hospitalised participants [1]. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - April 5, 2024 Category: Endocrinology Authors: Rahul D. Barmanray, Mervyn Kyi, Gerry Rayman, Robert Rushakoff, Philip Newland-Jones, Spiros Fourlanos Tags: Commentary Source Type: research

Corrigendum to “The AMD ANNALS: A continuous initiative for the improvement of type 2 diabetes care” [Diabetes Res. and Clin. Pract. 199 (2023) 110672]
The full list of collaborators in the AMD Annals Study Group can be viewed in the supplementary material now associated with this article. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - April 4, 2024 Category: Endocrinology Authors: G. Russo, P. Di Bartolo, R. Candido, G. Lucisano, V. Manicardi, A. Giandalia, A. Nicolucci, A. Rocca, M.C. Rossi, G. Di Cianni, on behalf of the AMD Annals Study Group Tags: Corrigendum Source Type: research

Bariatrics and endoscopic therapies for the treatment of metabolic disease: Past, present, and future
The burden of chronic metabolic diseases such as obesity, type 2 diabetes mellitus (T2DM), and metabolic dysfunction-associated steatotic liver disease (MASLD) and the urgency of the epidemiological situation necessitate the development of therapies that enhance metabolic health and alter the trajectory of metabolic disease in society. Certain bariatric-metabolic surgeries have proven to be effective approaches for treating metabolic dysfunction, showing remission or significant improvements in obesity, T2DM, and MASLD-related outcomes, suggesting that these interventions might be able to “reset” a pathologically calib...
Source: Diabetes Research and Clinical Practice - April 2, 2024 Category: Endocrinology Authors: Geltrude Mingrone, Harith Rajagopalan Source Type: research

Household food insecurity and associations with hemoglobin A1c and acute diabetes-related complications in youth and young adults with type 1 diabetes: The SEARCH for diabetes in youth study
To examine, among youth and young adults (YYA) with type 1 diabetes (T1D), the association of household food insecurity (HFI) with: 1) HbA1c and 2) episodes of diabetic ketoacidosis (DKA) and severe hypoglycemia. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - April 2, 2024 Category: Endocrinology Authors: Faisal S. Malik, Angela D. Liese, Alice Ellyson, Lauren A. Reid, Beth A. Reboussin, Katherine A. Sauder, Edward A. Frongillo, Catherine Pihoker, Dana Dabelea, Kristi Reynolds, Elizabeth T. Jensen, Santica Marcovina, Deborah A. Bowlby, Jason A. Mendoza, fo Source Type: research

Diagnostic performance of the GGT/HDL-C ratio for NAFLD in adults with obesity undergoing bariatric surgery
Non-alcoholic fatty liver disease (NAFLD) is the accumulation of fat in the liver, known as liver steatosis, in individuals who do not consume excessive amounts of alcohol and for whom secondary causes have been excluded [1]. This broad clinical spectrum ranges from benign or simple liver steatosis (NAFL) to non-alcoholic steatohepatitis (NASH), progressing to fibrosis and cirrhosis, and, ultimately, hepatocellular carcinoma (HCC) [2]. NAFLD has become the most common liver disease and affects a quarter of the global adult population. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - April 2, 2024 Category: Endocrinology Authors: Renzo Pajuelo-Vasquez, Jerry K. Benites-Meza, Hilda V. Durango-Chavez, Gustavo Salinas-Sedo, Carlos J. Toro-Huamanchumo Source Type: research