Prediction of 10-year Mortality using hs-CRP in Chinese People with Hyperglycemia: Findings from the Da Qing Diabetes Prevention Outcomes Study
The global epidemic of type 2 diabetes and the excess mortality associated with the disease have been the focus of strong research interest over the last decade. People with hyperglycemia have a higher risk of diabetes development [1], cardiovascular events [2], microvascular complications, and cardiovascular and all-cause mortality [3, 4]. Therefore, the identification of subjects with a higher risk of mortality among people with prediabetes and diabetes is vital in reducing the burden induced by type 2 diabetes, worldwide [5]. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - January 13, 2021 Category: Endocrinology Authors: Xin Qian, Siyao He, Jinping Wang, Qiuhong Gong, Yali An, Hui Li, Yanyan Chen, Guangwei Li Source Type: research

Microbiota thrombus colonization may influence AtheRo-thrombosIs in hyperglycemic pAtieNts with ST sEgment eLevation myocardiaLinfArction (STEMI). MARIANELLA study
We examined the association of the coronary thrombus microbiota and relative metabolites with major adverse cardiovascular events (MACE) in hyperglycemic patients with ST segment elevation myocardial infarction (STEMI). (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - January 13, 2021 Category: Endocrinology Authors: Celestino Sardu, Maria Consiglia Trotta, Biagio Santella, Nunzia D'Onofrio, Michelangela Barbieri, Maria Rosaria Rizzo, Ferdinando Carlo Sasso, Lucia Scisciola, Fabrizio Turriziani, Michele Torella, Michele Portoghese, Francesco Loreni, Simone Mureddu, Ma Source Type: research

Efficacy and safety of the glucagon-like peptide-1 receptor agonist oral semaglutide in patients with type 2 diabetes mellitus: a systematic review and meta-analysis
To evaluate the efficacy and safety of the glucagon-like peptide-1 (GLP-1) receptor agonist (RA) oral semaglutide in the treatment of type 2 diabetes mellitus (T2DM) patients. Methods: Randomized controlled trials comparing oral semaglutide with placebo or other antihyperglycemic agents in T2DM patients were identified by searching PubMed, Embase, Cochrane Library and ClinicalTrials.gov. Risk ratios and mean differences with 95% confidence intervals were used to synthesize the results. Results: Ten relevant studies involving 8,536 patients were finally included. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - January 9, 2021 Category: Endocrinology Authors: Jingxin Li, Ke He, Jun Ge, Caixia Li, Zeng Jing Source Type: research

Association between intake of white rice and incident type 2 diabetes – an updated meta-analysis
Meta-analyses on the association between white rice intake and incident type 2 diabetes (T2D) have been inconsistent. Since the last meta-analysis, more studies have been published with inconsistent results. We aimed to examine the rice-T2D association in Asian populations in an updated meta-analysis. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - January 7, 2021 Category: Endocrinology Authors: Guiying Ren, Juan Qi, Yuliang Zou Tags: Review Source Type: research

Women ’s Wellness with Type 2 Diabetes Program (WWDP): qualitative findings from the UK and Australian feasibility study
To undertake a qualitative study of a multimodal behavioural intervention and research protocol developed to improve wellness in women with type 2 diabetes mellitus (T2DM), the Women ’s Wellness with Type 2 Diabetes program (WWDP). (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - January 7, 2021 Category: Endocrinology Authors: Debra Anderson, Jackie Sturt, Nicole McDonald, Diksha Sapkota, Janine Porter-Steele, Rebecca Rogers, Ayako Temple, Charrlotte Seib, Amanda McGuire, Dian Tjondronegoro, Rosie Walker, Lena Al-Khudairy, Codi White Source Type: research

Shortened Relative Leukocyte Telomere Length is Associated with All-cause Mortality in Type 2 Diabetes- Analysis from the Hong Kong Diabetes Register
This study investigates the relationship between rLTL and the risk of death in Chinese patients with type 2 diabetes. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - January 7, 2021 Category: Endocrinology Authors: Feifei Cheng, Andrea O Luk, Hongjiang Wu, Cadmon KP Lim, Luke Carroll, Claudia HT Tam, Baoqi Fan, Aimin Yang, Eric SH Lau, Alex CW Ng, Heung Man Lee, Elaine Chow, Alice P Kong, Anthony C Keech, Mugdha V Joglekar, Wing Yee So, Alicia J Jenkins, Juliana CN Source Type: research

The mean of fasting, 1-h, and 2-h plasma glucose levels is superior to each separate index in predicting diabetes
We examined whether averaging these PG indices (GLUM0.60.120) results in a better predictor of future type 2 diabetes (T2DM). (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - January 7, 2021 Category: Endocrinology Authors: Duong Duc Pham, Young-Seon Lee, Shanyu Cui, Yunwan Jeon, Chae Hun Leem Source Type: research

Diabetes Mortality Across the 30 Biggest U.S. Cities: Assessing Overall Trends and Racial Inequities
Diabetes affects 34.2 million individuals in the United States (U.S.), with an additional 84.1 million with prediabetes and 7 million who are likely undiagnosed[1]. In 2017, over 270,000 Americans died of diabetes, making it the 7th leading cause of death [2]. In addition to high rates of mortality, diabetes and prediabetes (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - January 7, 2021 Category: Endocrinology Authors: Joanna Buscemi, Nazia Saiyed, Abigail Silva, Fereshteh Ghahramani, Maureen R. Benjamins Source Type: research

Diabesity negatively affects transferrin saturation and iron status. The DICARIVA study
Type 2 Diabetes Mellitus (T2DM) is a major systemic disease, which involves impaired pancreatic function and currently affects approximately 500 million people worldwide. The global burden of disease has risen in adults older than 18 years old. In 2019, there were 463 (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - January 7, 2021 Category: Endocrinology Authors: M. Pilar Vaquero, Miriam Mart ínez-Suarez, Ángel García-Quismondo, Francisco J. del Cañizo, Francisco J. Sánchez-Muniz Source Type: research

Our Language Matters: Improving communication with and about people with diabetes. A position statement by Diabetes Australia
The words used about diabetes affect the physical and emotional health of people living with diabetes. They also affect how individuals and society view people living with, or at risk of, diabetes. People with diabetes, their families, and people at risk of diabetes, need and deserve communications that are clear and accurate, respectful and inclusive, and free from judgement and bias. The aim of this position statement is to help bring about positive change in the language used about diabetes. It is based on 30+ years of research into the experiences of people with diabetes. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - January 7, 2021 Category: Endocrinology Authors: Speight J, Skinner TC, Dunning T, Black T, Kilov G, Lee C, Scibilia R, Johnson G Tags: Invited review Source Type: research

Effect of background insulin therapy on cardiovascular outcomes with SGLT-2 inhibitors in type 2 diabetes: A Meta-analysis of Cardiovascular Outcome Trials
Cardiovascular (CV) benefits of SGLT-2 inhibitors (SGLT-2i) have been consistent in type 2 diabetes mellitus (T2DM). To find whether SGLT-2i show similar CV effects with insulin therapy in T2DM, we conducted a trial-level meta-analysis of CV outcome trials. This meta-analysis found SGLT-2i exert CV benefit, irrespective of background insulin therapy. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - January 6, 2021 Category: Endocrinology Authors: Awadhesh Kumar Singh, Ritu Singh Source Type: research

Effect of Yoga intervention on biochemical, oxidative stress markers, inflammatory markers and sleep quality among subjects with type 2 diabetes in South India: Results from the SATYAM project
The aim of this study was to investigate the effect of yoga intervention on the biochemical, oxidative stress markers and inflammatory markers and sleep quality among subjects with type 2 diabetes. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 24, 2020 Category: Endocrinology Authors: Vijay Viswanathan, S. Sumathi, A. Sai Prathiba, D. Arutselvi, G. Leema, Satyavani Kumpatla Source Type: research

The role of the microbiome in diabetes mellitus
The microbiome is greatly significant for immune system development and homeostasis. Dysbiosis in gut microbial composition and function is linked to immune responses and the development of metabolic diseases, including diabetes mellitus (DM). However, skin microbiome changes in diabetic patients and their role in DM are poorly elucidated. In this review, we summarize recent findings about the association between the gut and skin microbiota and DM, highlighting their roles in the proinflammatory status of DM. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 24, 2020 Category: Endocrinology Authors: Shili Zhang, Yulan Cai, Chuzhen Meng, Xinyi Ding, Jiali Huang, Xiangrong Luo, Ying Cao, Fang Gao, Mengchen Zou Tags: Review Source Type: research

Prevalence of diabetes and pre-diabetes in Greece. Results of the First National Survey of Morbidity and Risk Factors (EMENO) study
The prevalence of diabetes mellitus has increased dramatically in recent decades, most markedly in the world ’s low-to-middle income countries [1], and this trend is projected to continue as the global population ages and becomes more obese [2]. Furthermore, diabetes usually remains (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 24, 2020 Category: Endocrinology Authors: Konstantinos Makrilakis, Natasa Kalpourtzi, Ioannis Ioannidis, Stella Iraklianou, Athanasios Raptis, Alexis Sotiropoulos, Magda Gavana, Apostolos Vantarakis, Maria Kantzanou, Christos Hadjichristodoulou, Grigoris Chlouverakis, Grigoris Trypsianis, Paraske Source Type: research

Risk of hypoglycemia in Japanese people with type 2 diabetes mellitus who initiated or switched to insulin glargine 300 U/mL: A subgroup analysis of 12-month post-marketing surveillance study (X-STAR study)
Insulin therapy is an established option to improve glycemic control in people with type 2 diabetes (T2D) and, in reality, tends to be reserved for those with advanced stage of diabetes. Insulin is highly efficacious in terms of lowering glucose; however, it imposes potential hypoglycemic risk (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 24, 2020 Category: Endocrinology Authors: Takahisa Hirose, Masato Odawara, Munehide Matsuhisa, Ryusuke Koshida, Masayuki Senda, Yasushi Tanaka, Yasuo Terauchi Source Type: research

The impact of periodontal treatment on healthcare costs in newly diagnosed diabetes patients: Evidence from a German claims database
The global-, regional-, and country-level prevalence of diabetes mellitus (DM) have been increasing for many years [1,2]. In 2015, 9.8% of the German population suffered from DM [3] and this is set to increase by 77% until 2040. The expectation is that this will further exacerbate healthcare costs [4,5]. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 23, 2020 Category: Endocrinology Authors: Katja Blaschke, Martin Hellmich, Christina Samel, Stefan Listl, Ingrid Schubert Source Type: research

Increasing prevalence of Gestational Diabetes Mellitus when implementing the IADPSG criteria: a systematic review and meta-analysis
Quantify the proportional increase in gestational diabetes (GDM) prevalence when implementing the new International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria compared to prior GDM criteria, and to assess risk factors that might affect the change in prevalence. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 23, 2020 Category: Endocrinology Authors: Maryam Saeedi, Yang Cao, Helena Fadl, Hanne Gustafson, David Simmons Source Type: research

Effectiveness and equity of continuous subcutaneous insulin infusions in pediatric type 1 diabetes: a systematic review and meta-analysis of the literature
Continuous subcutaneous insulin infusions (CSII) are gaining ground over multiple-daily injections (MDI) as a standard therapy for pediatric type 1 diabetes [1]. A number of clinical trials have highlighted that the CSII improve glycemic outcomes, promote patient-centered decisions, and reduce the burden of diabetes care in children and adolescents with type 1 diabetes [2 –9]. However, most of the trials in this field lacked data on clinical effectiveness, the extent to which clinical efficacy of CSII translates into better glycemic outcomes in a real-world setting [10,11]. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 23, 2020 Category: Endocrinology Authors: Tiago Jeronimo Dos Santos, Juan de Mata Donado Campos, Jes ús Argente, Fernando Rodríguez-Artalejo Tags: Review Source Type: research

Glycemic index versus glycemic load – What does matter in life?
Glycemic index, a carbohydrate quality classification, ranks the impact of isoglucidic foods based on their carbohydrate absorption and glycemic response [1]. The clinical relevance of (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 22, 2020 Category: Endocrinology Authors: Maria Pallayova Tags: Letter to the Editor Source Type: research

COVID-19 pandemic: can fasting plasma glucose and HbA1c replace the oral glucose tolerance test to screen for hyperglycaemia in pregnancy?
To evaluate proposals considering HbA1c and fasting plasma glucose (FPG) measurement as a substitute for oral glucose tolerance test (OGTT) to diagnose hyperglycaemia in pregnancy (HIP) during COVID-19 pandemic. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 22, 2020 Category: Endocrinology Authors: Charlotte Nachtergaele, Eric Vicaut, Sara Pinto, Sopio Tatulashvili, H élène Bihan, Meriem Sal, Narimane Berkane, Lucie Allard, Camille Baudry, Lionel Carbillon, Emmanuel Cosson Source Type: research

Technological innovation of Continuous Glucose Monitoring (CGM) as a tool for commercial aviation pilots with insulin-treated diabetes and stakeholders/regulators: a new chance to improve the directives?
Civil aviation pilots who develop insulin-treated diabetes and want to renew a Commercial Pilot License (CPL) represent a medical, social and regulatory problem. This depends on justified concerns about hypoglycemia, the most threatening event for people who carry out jobs requiring a high level of concentration and reliability. This negatively affects social and working aspects of pilots ’ lives, who have a high profile and a high-cost professional qualification. It could be possible now to revise this attitude thanks to the availability of Continuous Glucose Monitoring (CGM) devices. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 21, 2020 Category: Endocrinology Authors: F. Strollo, A. Furia, P. Verde, A. Bellia, M. Grussu, A. Mambro, M.D. Petrelli, S. Gentile Tags: Review Source Type: research

Continuous subcutaneous insulin infusion does not correspond with pregnancy outcomes despite better glycemic control as compared to multiple daily injections in type 1 diabetes – significance of pregnancy planning and prepregnancy HbA1c
The aim of the study was to compare pregnancy outcomes with glycemic control, total increase in insulin requirement, and body weight gain in the women with Type 1 Diabetes Mellitus (T1DM) using continuous subcutaneous insulin infusion (CSII) or multiple daily injections (MDI). (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 21, 2020 Category: Endocrinology Authors: Monika Żurawska-Kliś, Marcin Kosiński, Andżelika Kuchnicka, Milena Rurka, Judyta Hałucha, Marzena Wójcik, Katarzyna Cypryk Source Type: research

Genetic variants of TCF7L2 gene and its coherence with metabolic parameters in Lithuanian (Kaunas district) women population with previously diagnosed Gestational Diabetes Mellitus compared to General Population
To determine the association of genetic variants rs7901695, rs7903146, rs7895340, rs11196205, rs12255372 of transcription factor 7 like 2 (TCF7L2) gene and its coherence with metabolic parameters in Lithuanian (Kaunas district) women population with previously diagnosed gestational diabetes mellitus (GDM) and to compare the prevalence of TCF7L2 single nucleotide polymorphism (SNP) results to general population. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 19, 2020 Category: Endocrinology Authors: Migle Francaite-Daugeliene, Vaiva Lesauskaite, Abdonas Tamosiunas, Aldona Jasukaitiene, Dzilda Velickien ė Source Type: research

Type 2 Diabetes and viral infection; cause and effect of disease
The recent pandemic of COVID-19 has made abundantly clear that Type 2 diabetes (T2D) increases the risk of more frequent and more severe viral infections. At the same time, pro-inflammatory cytokines of an anti-viral Type-I profile promote insulin resistance and form a risk factor for development of T2D. What this illustrates is that there is a reciprocal, detrimental interaction between the immune and endocrine system in the context of T2D. Why these two systems would interact at all long remained unclear. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 19, 2020 Category: Endocrinology Authors: Tamara Turk Wensveen, Dora Ga šparini, Dario Rahelić, Felix M. Wensveen Tags: Review Source Type: research

The International Diabetes Federation ’s Guide for Diabetes Epidemiological Studies
The global prevalence of diabetes mellitus has been increasing steadily for over 50 years and has now reached pandemic proportions. The prevalence of both diagnosed and undiagnosed diabetes was estimated to be 9.3% (463 million people) in 2019, and is projected to rise to 10.2% (578 million) by 2030 and 10.9% (700 million) by 2045 [1]. The rising prevalence of diabetes is related to aging populations and wider adoption of unhealthy life-styles, resulting in higher prevalence of obesity [2]. In 2006, the United Nations Resolution 61/225 encouraged all nations to develop national policies for the prevention, care and treatme...
Source: Diabetes Research and Clinical Practice - December 18, 2020 Category: Endocrinology Authors: Pablo Aschner, Suvi Karuranga, Steven James, David Simmons, Abdul Basit, Jonathan Shaw, Sarah H. Wild, Katherine Ogurtsova, Pouya Saeedi, on behalf of the International Diabetes Federation's Diabetes Epidemiological Guide Writing Group Tags: Editorial Source Type: research

Characterization of hyperglycemia in patients receiving immune checkpoint inhibitors: beyond autoimmune insulin-dependent diabetes
Immune-mediated beta cell destruction is known to cause hyperglycemia in patients receiving immune checkpoint inhibitor (ICI) cancer therapy. However, it is uncommon, and little is known about the full spectrum of hyperglycemia in patients receiving ICIs. We aimed to characterize the prevalence and factors associated with hyperglycemia in patients treated with ICIs. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 18, 2020 Category: Endocrinology Authors: Amanda Leiter, Emily Carroll, Danielle Brooks, Jennifer Ben Shimol, Elliot Eisenberg, Juan P. Wisnivesky, Matthew D. Galsky, Emily J. Gallagher Source Type: research

Are Spexin Levels Associated with Metabolic Syndrome, Dietary Intakes and Body Composition in Children?
Spexin (neuropeptide Q) is a novel neuropeptide chiefly produced in human white adipose tissue, and is now implicated as a potential signal which might affect regulation of body weight, energy and glucose homeostasis, satiety, lipid metabolism and immune responses. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 18, 2020 Category: Endocrinology Authors: Maryam Behrooz, Elnaz Vaghef Mehrabani, Jalal Moludi, Alireza Ostadrahimi Source Type: research

Can patterns of medication use explain the increasing incidence of End Stage Kidney Disease among people with diabetes in Australia?
Recently, an increase in the incidence of end-stage kidney disease (ESKD) among people with type 2 diabetes (T2D) aged (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 18, 2020 Category: Endocrinology Authors: Oyunchimeg Buyadaa, Digsu N Koye, Richard Ofori-Asenso, Jenni IIomaki, Stephen J Wood, Jonathan E Shaw, Dianna J Magliano Source Type: research

Development and Validation of a Diabetes Mellitus Treatment Adherence Scale
The aim of this study was to develop a Diabetes Mellitus Treatment Adherence Scale (DMTAS) to fill the gap in the internationally accepted comprehensive scale. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 18, 2020 Category: Endocrinology Authors: Guoqiang Hou, Ziwei Fang, Wenjun Cao, Yan Shi, Xinrong Xu, Mei Han, Jiaxin Dong Source Type: research

Widespread sensory neuropathy in diabetic patients hospitalized with severe COVID-19 infection
To characterize the distribution and severity of sensory neuropathy using a portable quantitative sensory testing (QST) device in diabetic patients (DM) hospitalized with severe COVID-19 infection. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 17, 2020 Category: Endocrinology Authors: Ariel Odriozola, Luc ía Ortega, Lidia Martinez, Samantha Odriozola, Ainhoa Torrens, David Corroleu, Silvia Martínez, Meritxell Ponce, Yolanda Meije, Mercedes Presas, Alejandra Duarte, M. Belén Odriozola, Rayaz A. Malik Source Type: research

Correction to the Bergman Review
To the Editor: (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 17, 2020 Category: Endocrinology Authors: Mayer B. Davidson Tags: Letter to the Editor Source Type: research

Incretin based therapies and sglt-2 inhibitors in kidney transplant recipients with diabetes: a systematic review and meta-analysis
Diabetes mellitus (DM) following kidney transplantation is a common complication associated with adverse long-term outcomes including higher rates of cardiovascular disease as well as impaired allograft and patient survival [1-4]. Although the lack of a unanimously adopted definition for DM in transplantation has led to heterogeneous reporting of data regarding epidemiology of DM in renal transplant recipients (RTRs), it is estimated to affect up to one-third of RTRs with no history of DM prior to transplantation [5]. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 15, 2020 Category: Endocrinology Authors: Dora Oikonomaki, Evangelia Dounousi, Anila Duni, Stefanos Roumeliotis, Vassilios Liakopoulos Source Type: research

Incidence and Predictors of Type 1 Diabetes among Younger Adults Aged 20-45 Years: The Diabetes in Young Adults (DiYA) Study
To estimate incidence of type 1 diabetes (T1D) and to develop a T1D prediction model among young adults. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 15, 2020 Category: Endocrinology Authors: Jean M. Lawrence, Jeff M. Slezak, Charles Quesenberry, Xia Li, Liping Yu, Marian Rewers, Janet G. Alexander, Harpreet S. Takhar, Sneha Sridhar, Ann Albright, Deborah B. Rolka, Sharon Saydah, Giuseppina Imperatore, Assiamira Ferrara Source Type: research

The absolute and relative risk of type 2 diabetes after gestational diabetes: A systematic review and meta-analysis of 129 studies
Gestational diabetes mellitus (GDM) is one of the most common conditions of pregnancy. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 14, 2020 Category: Endocrinology Authors: Rebecca A Dennison, Eileen S Chen, Madeline E Green, Chloe Legard, Deeya Kotecha, George Farmer, Stephen J Sharp, Rebecca J Ward, Juliet A Usher-Smith, Simon J Griffin Source Type: research

Effect of Serum Zinc and Copper Levels on Insulin Secretion, Insulin Resistance and Pancreatic β cell Dysfunction in US Adults: Findings from the National Health and Nutrition Examination Survey (NHANES) 2011-2012
Incidence and prevalence of type 2 diabetes mellitus (T2DM) has been steadily increasing both in developed and developing countries over the last decade 1. In the United States the cost of diagnosed diabetes was estimated to be $327 billion in 2017 with 1 in 4 health care dollars spent for the care of patients with diabetes 2. Given the morbidity and mortality as well as cost associated with T2DM and its complications, there is a great need to identify ways to prevent diabetes. The Diabetes Prevention Program (DPP) showed that lifestyle intervention, a minimum of 7% weight loss/weight maintenance and a minimum of 150 minut...
Source: Diabetes Research and Clinical Practice - December 14, 2020 Category: Endocrinology Authors: Ravi Kant, Vipin Verma, Siddharth Patel, Rashmi Chandra, Rahul Chaudhary, Alan R. Shuldiner, Kashif M. Munir Source Type: research

Glucose Tolerance in a Cohort of Egyptian Children after Kidney Transplantation
The evolution of the field of pediatric kidney transplantation over the last 25 years has been associated with improved allograft function and reduced acute rejection rates [1,2]. Unfortunately, the long term survival is still suboptimal. Chronic allograft nephropathy (CAN) and long term cardiovascular (CV) problems are the most important causes of morbidity and mortality among pediatric and adult transplant recipients [3,4]. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 14, 2020 Category: Endocrinology Authors: Noha Arafa, Hafez M. Bazaraa, Heba Sharaf ElDin, Mofeeda Hussein, Doaa M. Salah Source Type: research

Gestational diabetes in Korea: temporal trends in prevalence, treatment, and short-term consequences from a national health insurance claims database between 2012 and 2016 Running head: Gestational diabetes mellitus in Korea 2012 –2016
Gestational diabetes mellitus (GDM) is the most common medical complication in pregnancy and its prevalence is increasing substantially across the world and is expected to continue to increase (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 11, 2020 Category: Endocrinology Authors: Chan-Hee Jung, Sang-Hee Jung, Dughyun Choi, Bo-Yeon Kim, Chul-Hee Kim, Ji-Oh Mok Source Type: research

Mitigation of hypoglycemia during Ramadan using the flash glucose monitoring system following dose adjustment of insulin and sulphonylurea in patients taking multiple glucose-lowering therapies (The PROFAST-IT Study)
and HypothesisPatients with type-2 diabetes mellitus (T2DM) on multiple glucose-lowering therapies who fast during Ramadan are at increased risk of hypoglycemia. We have assessed the utility of the flash glucose monitoring system after adjusting the dose of insulin and sulphonylureas to mitigate the risk of hypoglycemia in patients with T2DM who fast during Ramadan. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 11, 2020 Category: Endocrinology Authors: Tarik Elhadd, Mohamed Bashir, Khaled A Baager, Hamda A Ali, Dabia H S Almohannadi, Zainab Dabbous, Rayaz A Malik, Abdul-Badie Abou-Samra, for the PROFAST Ramadan Study Group Source Type: research

Nephrotic Range Proteinuria associated with Focal Segmental Glomerulosclerosis Reversed with Pioglitazone Therapy in a Patient with Dunnigan Type  Lipodystrophy
Familial partial lipodystrophy(FPLD) is a rare disorder associated with severe insulin resistance, hypertriglyceridemia, low serum HDL cholesterol and proteinuric renal disease. Although proteinuric renal disease is not common among in patients with partial lipodystrophy, we report a patient with Dunnigan type FPLD complicated by nephrotic syndrome which resolved following treatment with the PPAR γ agonist pioglitazone, CPAP, diet, and exercise. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 11, 2020 Category: Endocrinology Authors: Anjul Sharma, Raymond E. Bourey, John C. Edwards, David S. Brink, Stewart G. Albert Tags: Brief Report Source Type: research

Cumulative long-term recurrence of diabetic foot ulcers in two cohorts from centres in Germany and the Czech Republic
Our aim was to comprehensively estimate the incidence of diabetic foot ulcer (DFU) recurrence and corresponding risk factors in two cohorts. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 11, 2020 Category: Endocrinology Authors: Katherine Ogurtsova, Stephan Morbach, Burkhard Haastert, Michal Dubsk ý, Gerhard Rümenapf, Dan Ziegler, Alexandra Jirkovska, Andrea Icks Source Type: research

Perinatal outcomes and offspring growth profiles in twin pregnancies complicated by gestational diabetes mellitus: a longitudinal cohort study
Gestational diabetes mellitus (GDM) is one of the most common pregnancy complications, in which glucose intolerance is initially detected during pregnanc[1]. The overall prevalence of GDM is increasing globally due to advanced maternal age in pregnancy, increased rate of obesity and stricter diagnostic criteria with more universal testing[2]. The reported prevalence of GDM ranges from 1.8 to 31.5% depending on different diagnostic criteria and population studied[3]. The criteria reported by theInternational Association of Diabetes and Pregnancy Study Groups (IADPSG) in 2011 are widely accepted by most hospitals in China an...
Source: Diabetes Research and Clinical Practice - December 11, 2020 Category: Endocrinology Authors: Youwen MEI, Jiaxiao YU, Li WEN, Xin FAN, Yan Zhao, Jie Li, Juan Qiao, Huijia FU, Pamela LEONG, Richard SAFFERY, Qi TONG, Mark D.KILBY, Hongbo QI, Chao TONG, Philip N. BAKER Source Type: research

Ramadan fasting in people with type 1 diabetes during COVID-19 pandemic: The DaR Global survey
The DaR Global survey was conducted to determine the impact of the COVID-19 pandemic on the intentions to fast and the outcomes of fasting in (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 11, 2020 Category: Endocrinology Authors: Mohamed Hassanein, Reem M. Alamoudi, Majd-Aldeen Kallash, Naji J. Aljohani, Eman M. Alfadhli, Lobna El Tony, Ghofran S. Khogeer, Abdulaziz F. Alfadhly, Ahmed ElMamoon Khater, Muhammad Yakoob Ahmedani, Mehmet Akif Buyukbese, Inass Shaltout, Jamal Belkhadir Source Type: research

Order of Discontinuation of Glucose-lowering Medications following Bariatric Surgery
According to the American Society for Metabolic and Bariatric Surgery, the estimated number of bariatric surgeries performed in 2018 was 252,000 which represents a 91% increase from 113,000 surgeries in 2006.1,2 In addition to the obesity epidemic, one potential reason for this increasing trend is the positive impact of bariatric surgery on Type 2 diabetes mellitus (T2DM). Bariatric surgery can be considered in patients with T2DM who have a body mass index (BMI) of ≥40 kg/m2, BMI between 35.0-39.9 kg/m2 with hyperglycemia that is inadequately controlled by lifestyle and optimal glucose-lowering medications (GLMs), or BM...
Source: Diabetes Research and Clinical Practice - December 11, 2020 Category: Endocrinology Authors: Scott Martin Vouri, Jiajing Chen, Jayme Sparkman, Arghavan Salles, Scott T Micek Source Type: research

Ramadan Fasting and Diabetes 2019: The Year in Review
The literature on health aspects of Ramadan fasting is widely spread in many journals making it not readily available to those interested in the subject. Materials and Methods: A narrative, non-systematic review of the international literature from two major online databases (viz. Scopus, PubMed) in one year (2019). The search term “Ramadan fasting AND Diabetes” was used, and relevant literature was narrated in a concise thematic account. Results: Research design included qualitative, quantitative, and mixed methods. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 11, 2020 Category: Endocrinology Authors: Salem A Beshyah, Khawla F Ali, Khadija Hafidh, Issam M Hajjaji Tags: Review Source Type: research

The association between lipoprotein (a) and carotid atherosclerosis in patients with type 2 diabetes without pre-existing cardiovascular disease: A cross-sectional study
Lipoprotein (a) [Lp(a)] consists of apolipoprotein B-100 and apolipoprotein (a) [1], which has several pathogenic roles for atherosclerosis due to the similarity to low-density lipoprotein cholesterol (LDL-C) and thrombosis due to the similarity to plasminogen [2]. As expected, the risk of cardiovascular disease (CVD) including coronary heart disease (CHD), major coronary events, myocardial infarction, stroke, and all-cause mortality was elevated in general populations with elevated Lp(a) level [3-5]. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 11, 2020 Category: Endocrinology Authors: Ji Eun Jun, Hongsun Kang, You-Cheol Hwang, Kyu Jeung Ahn, Ho Yeon Chung, In-Kyung Jeong Source Type: research

Analysis of the effectiveness of second oral glucose-lowering therapy in routine clinical practice from the Mediterranean area: A retrospective cohort study
Type 2 diabetes mellitus (T2DM) is a heterogeneous condition characterized by progressive deterioration of glycaemic control that with time usually requires the combination of several antidiabetic drugs with different mechanisms of action. Additionally, T2DM carries a high risk for cardiovascular diseases (CVD) due to cardiovascular risk factors including overweight, hypertension, smoking, family history of premature coronary disease, chronic kidney disease, albuminuria and dyslipidaemia [1]. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 10, 2020 Category: Endocrinology Authors: Bogdan Vlacho, Xavier Mundet-Tudur í, Manel Mata-Cases, Joan Antoni Vallès-Callol, Jordi Real, Magí Farré, Xavier Cos, Kamlesh Khunti, Dídac Mauricio, Josep Franch-Nadal Source Type: research

Management of patients with diabetes and obesity in the COVID-19 era: experiences and learnings from South and East Europe, the Middle East, and Africa
The COVID-19 pandemic has had a major effect on healthcare during 2020. Current evidence suggests that, while individuals with diabetes and obesity are no more prone to SARS-CoV-2 infection than those without, the risk of hospitalisation if someone has diabetes or obesity and then contracts COVID-19 is three times higher – and 4.5 times higher if they have diabetes and obesity. We assembled a panel of experts from South and East Europe, the Middle East, and Africa to discuss the challenges to management of diabetes and obesity during and post the COVID-19 pandemic. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 10, 2020 Category: Endocrinology Authors: Francesco Giorgino, Sindeep Bhana, Leszek Czupryniak, Selcuk Dagdelen, Gagik R. Galstyan, Andrej Jane ž, Nebojsa Lalić, Nassim Nouri, Dario Rahelić, Anca Pantea Stoian, Itamar Raz Tags: Review Source Type: research

Intragastric administration of leucine and isoleucine does not reduce the glycaemic response to, or slow gastric emptying of, a carbohydrate-containing drink in type 2 diabetes
This study aimed to evaluate the effects of leucine and isoleucine on postprandial glycaemia and gastric emptying in type-2 diabetes mellitus (T2D). (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 10, 2020 Category: Endocrinology Authors: Rachel A Elovaris, Maryam Hajishafiee, Sina S Ullrich, Penelope CE Fitzgerald, Kylie Lange, Michael Horowitz, Christine Feinle-Bisset Source Type: research

Association of metformin with mortality or ARDS in patients with COVID-19 and type 2 diabetes: a retrospective cohort study
To determine the association between metformin use and mortality and ARDS incidence in patients with COVID-19 and type 2 diabetes. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 10, 2020 Category: Endocrinology Authors: Nan Jiang, Zhenyuan Chen, Xiaoxv Yin, Li Liu, Heping Yang, Xiangping Tan, Jing Wang, Hui Li, Mengge Tian, Zuxun Lu, Nian Xiong, Yanhong Gong Source Type: research

High admission blood glucose independently predicts poor prognosis in COVID-19 patients: A systematic review and dose-response meta-analysis
The rapidly spreading coronavirus disease 2019 (COVID-19) pandemic has placed significant burdens on healthcare systems worldwide, with millions of cases and hundred-thousands of deaths.[1] This is further aggravated by the fact that COVID-19 patients are at risk of rapid health deteriorations leading to multiorgan failure and death[2], indicating that early and (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - December 9, 2020 Category: Endocrinology Authors: Gilbert Lazarus, Jessica Audrey, Vincent Kharisma Wangsaputra, Alice Tamara, Dicky L. Tahapary Source Type: research