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Epidemiology of NAFLD – Focus on diabetes
There is increasing appreciation of the complex interaction between nonalcoholic fatty liver disease (NAFLD) with type 2 diabetes (T2D) and insulin resistance. Not only is the prevalence of NAFLD disease high among patients with T2D, the liver disease is also more progressive. Currently, the global prevalence of NAFLD in the general population (2016 –2019) is 38 %. The prevalence of T2D among those with NAFLD is approximately 23 % while the prevalence of NAFLD among those with T2D can be as high as 70 %. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - April 1, 2024 Category: Endocrinology Authors: Zobair M. Younossi, Linda Henry Source Type: research

International Diabetes Federation position statement recommending use of 1-hour plasma glucose test to diagnose intermediate hyperglycaemia and type 2 diabetes
The International Diabetes Federation (IDF) has released a Position Statement that presents the 1-hour post-load plasma glucose (1-h PG) test as a more sensitive and practical method to screen for intermediate hyperglycaemia (IH) and type 2 diabetes(T2D) in people at risk. The Statement was prepared by an international panel* of 22 experts from 15 countries and presented at the 17th International Conference on Advanced Technologies& Treatments for Diabetes (ATTD) in Florence, Italy and was published online in Diabetes Research and Clinical Practice. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - March 30, 2024 Category: Endocrinology Source Type: research

Cardiovascular risk and access to primary care: Comparisons among Chinese documented and undocumented immigrants
Preventive strategies have led most European countries to a reduction in cardiovascular events over recent decades although inequalities remain in disadvantaged groups such as low-socioeconomic status and immigrant populations [1,2]. Several studies highlighted that in Europe the age-standardized prevalence of cardio-metabolic diseases is higher among non-native ethnic minority groups than among the native population [3,4]. Systematic reviews and single cohort studies did not include undocumented migrants, defined in the European Union (EU) context as third-country nationals present in the territory of a Schengen State who...
Source: Diabetes Research and Clinical Practice - March 28, 2024 Category: Endocrinology Authors: Alessio Pellegrino, Maria Calabrese, Maria Boddi, Irene Vacirca, Cecilia Baccari, Laura Bonvicini, Francesco Venturelli, Alessio Petrelli, Anteo Di Napoli, Maria Perticone, Paolo Giorgi Rossi, Pietro Amedeo Modesti Source Type: research

Frequency of brain ventricular enlargement among patients with diabetes mellitus
To determine the prevalence of dilated ventricles and concomitant high blood glucose measures. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - March 27, 2024 Category: Endocrinology Authors: Antonio Curr à, Riccardo Gasbarrone, Patrizia Gargiulo, Aurelia Rughetti, Simone Peschillo, Carlo Trompetto, Luca Puce, Lucio Marinelli, Francesco Fattapposta, Nicola Luigi Bragazzi, Paolo Missori Source Type: research

The effect of preprandial versus postprandial physical activity on glycaemia: Meta-analysis of human intervention studies
This meta-analysis aims to investigate the effect of preprandial physical activity (PA) versus postprandial PA on glycaemia in human intervention studies. Medline and Embase.com were searched until February 2023 for intervention studies in adults, directly comparing preprandial PA versus postprandial PA on glycaemia. Studies were screened using ASReview (34,837) and full text was read by two independent reviewers (42 full text, 28 included). Results were analysed using pooled mean differences in random-effects models. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - March 26, 2024 Category: Endocrinology Authors: Romy Slebe, Eva Wenker, Linda J. Schoonmade, Emma J Bouman, Denis P. Blondin, David J.T. Campbell, Andr é C. Carpentier, Joris Hoeks, Parminder Raina, Patrick Schrauwen, Mireille J. Serlie, Dirk Jan Stenvers, Renée de Mutsert, Joline W.J. Beulens, Femke Tags: Review Source Type: research

Remnant cholesterol is an independent risk factor for the incidence of chronic kidney disease in newly-diagnosed type 2 diabetes: A nationwide population-based study
Globally, 10.5% of the adult population has diabetes, which suggests that one in eight adults will be living with diabetes by 2045 [1]. Diabetes is a serious public health concern, leading to morbidity, disability and mortality mainly through the onset of cardiovascular disease (CVD) and other chronic complications [2]. Although the rate of hospitalization and mortality caused by major cardiovascular complications has decreased in Korea owing to overall improvements in managing cardiovascular risk factors like blood pressure, smoking, and lipid levels and with proper treatment of cardiovascular events [3], the prevalence o...
Source: Diabetes Research and Clinical Practice - March 26, 2024 Category: Endocrinology Authors: Soo Yeon Jang, Min Woong Kang, Eyun Song, Ahreum Jang, Kyung Mook Choi, Sei Hyun Baik, Hye Jin Yoo Source Type: research

Triglyceride-glucose index predicts type 2 diabetes mellitus more effectively than oral glucose tolerance test-derived insulin sensitivity and secretion markers
Owing to the recent increase in the prevalence of type 2 diabetes mellitus (T2DM) and prediabetes, a rapid rise in the socio-economic burden has been observed. According to the International Diabetes Federation, the global prevalence of diabetes among adults aged 20 –79 years was estimated to be 10.5 % (536.6 million people) in 2021, and the prevalence is projected to increase to approximately 12.2 % (783.2 million) in 2045 [1]. Additionally, global health expenditures related to diabetes are estimated to have reached 966 billion dollars in 2021, and th ey are predicted to rise to 1,054 billion USD by the year 2045...
Source: Diabetes Research and Clinical Practice - March 26, 2024 Category: Endocrinology Authors: Min Jin Lee, Ji Hyun Bae, Ah Reum Khang, Dongwon Yi, Mi Sook Yun, Yang Ho Kang Source Type: research

Ongoing burden and recent trends in severe hospitalised hypoglycaemia events in people with type 1 and type 2 diabetes in Scotland: A nationwide cohort study 2016 –2022
We examined severe hospitalised hypoglycaemia (SHH) rates in people with type 1 and type 2 diabetes in Scotland during 2016 –2022, stratifying by sociodemographics. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - March 26, 2024 Category: Endocrinology Authors: William Berthon, Stuart J. McGurnaghan, Luke A.K. Blackbourn, Joseph Mellor, Fraser W. Gibb, Simon Heller, Brian Kennon, Rory J. McCrimmon, Sam Philip, Naveed Sattar, Paul M. McKeigue, Helen M. Colhoun, Scottish Diabetes Research Network Epidemiology Grou Source Type: research

Causal relationship between gestational diabetes and preeclampsia: A bidirectional mendelian randomization analysis
The study aimed to explore the potential causal link between gestational diabetes mellitus (GDM) and preeclampsia (PE) using a bidirectional mendelian randomization (MR) analysis. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - March 26, 2024 Category: Endocrinology Authors: Xiaofeng Yang, QimeiZhong, Mengwei Huang, Li Li, Chunyan Tang, Shujuan Luo, Lan Wang, Hongbo Qi Source Type: research

Long-term lifestyle intervention can reduce the development of type 2 diabetes mellitus in subjects with prediabetes: A systematic review and meta-analysis
Prediabetes (PD) is a condition defined by blood glucose levels higher than normal but below diabetes thresholds. The term was proposed by the American Diabetes Association (ADA) to represent subjects with impaired glucose tolerance and/or impaired fasting glucose [1]. The condition is associated with an increased risk of microvascular and macrovascular complications [2]. In 2016, PD affected 318 million people worldwide and it is estimated that more than 470 million people may have prediabetes by 2030 [3]. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - March 26, 2024 Category: Endocrinology Authors: Paula Portal Teixeira, Kelly Pozzer Zucatti, Lucas Strassburger Matzenbacher, Laura Fink Wayerbacher, Minghui Zhang, Ver ônica Colpani, Fernando Gerchman Source Type: research

Effects of long-term HbA1c variability on serious infection risks in patients with type 2 diabetes and the influence of age, sex and ethnicity: A cohort study of primary care data
There is increasing evidence that long-term glycaemic (HbA1c) variability may be a predictive marker for poor health outcomes and mortality among people with diabetes[1,2]. It is well established that maintaining lower levels of HbA1c can reduce the risk of microvascular complications and cardiovascular events in patients with type 2 diabetes (T2D)[3]. Systematic review(s) have more recently highlighted many studies that have now demonstrated a risk of diabetes complications, such as renal disease, associated with the variability in HbA1c measurements recorded over several years, which acts independently of the level of Hb...
Source: Diabetes Research and Clinical Practice - March 26, 2024 Category: Endocrinology Authors: Iain M Carey, Julia A Critchley, Umar A R Chaudhry, Derek G Cook, Stephen DeWilde, Elizabeth S Limb, Liza Bowen, Stephen Woolford, Peter H Whincup, Naveed Sattar, Arshia Panahloo, Tess Harris Source Type: research

Once-weekly insulin as novel treatment for type 2 diabetes mellitus: A systematic review and meta-analysis of randomized clinical trials
The primary objective of this investigation is to examine the efficacy and safety of once-weekly insulin formulation when compared to regular basal insulin for the management of type 2 diabetes mellitus (T2DM). (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - March 25, 2024 Category: Endocrinology Authors: Nanny Natalia Mulyani Soetedjo, Hikmat Permana, Timotius Ivan Hariyanto, Marshell Tendean, Maya Kusumawati, Ervita Ritonga, Theo Audi Yanto, Ketut Suastika Source Type: research

International Diabetes Federation Position Statement on the 1-hour post-load plasma glucose for the diagnosis of intermediate hyperglycaemia and type 2 diabetes
We appreciate the important comments raised by Dr. Thirunavukkarasu. While we agree that adding other measurements to the 1-h post-load plasma glucose such as fasting and/or 2-hour glucose determinations can further augment the stratification of risk for type 2 diabetes (T2D) and complications of hyperglycemia, the fundamental objective of the International Diabetes Federation Position Statement [1] was to provide practical and economically feasible recommendations that could be implemented globally. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - March 25, 2024 Category: Endocrinology Authors: Michael Bergman, Jaakko Tuomilehto Tags: Letter to the Editor Source Type: research

Corrigendum to “Efficacy and safety of basal insulin degludec 100 IU/mL versus glargine 300 IU/mL for type 1 diabetes: The single-center INEOX randomized controlled trial” [Diabetes Res. Clin. Pract. 196 (2023) 110238]
The authors regret that the above-mentioned article did not mention that the INEOX project received funding from the European Union. The funding statement should be corrected as follows: (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - March 21, 2024 Category: Endocrinology Authors: Mar ía-Soledad Ruiz-de-Adana, Marta-Elena Domínguez, Virginia Morillas, Natalia Colomo, Rosario Vallejo-Mora, Mercedes Guerrero, Eva García-Escobar, Mónica Carreira, Yanina Romero-Zerbo, Francisca Linares, Isabel González-Mariscal, Francisco-Javier B Tags: Corrigendum Source Type: research

Determinants of health and mortality in undiagnosed diabetes: A nationally representative US adult, 2011 –2020
This study examines the determinants of health and mortality associated with undiagnosed diabetes among a nationally representative sample of US adults. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - March 21, 2024 Category: Endocrinology Authors: Ji Young Choi, Mohammed K. Ali, Daesung Choi Source Type: research