Alginate-based 3D cell culture technique to evaluate the half-maximal inhibitory concentration: an in vitro model of anticancer drug study for anaplastic thyroid carcinoma
ConclusionsThe findings of this study are beneficial for developing in vitro ATC 3D models to analyze the efficacy of different chemotherapy drugs and formulations. (Source: Thyroid Research)
Source: Thyroid Research - December 3, 2021 Category: Endocrinology Source Type: research

Is Hashimoto thyroiditis associated with increasing risk of thyroid malignancies? A systematic review and meta-analysis
ConclusionAlthough we found a significant association between HT and some types of TCs, High RoB studies, high level of heterogeneity, and the limited number of well-designed prospective studies, suggested the need for more studies to reach more reliable evidence. (Source: Thyroid Research)
Source: Thyroid Research - December 3, 2021 Category: Endocrinology Source Type: research

Nutritional iodine status and obesity
AbstractIodine is an essential component of the thyroid hormones, thyroxine and triiodothyronine. Its availability strictly depends on iodine content of foods, which may vary from very low to very high. Inadequate iodine intake (deficiency or excess) may affect thyroid function resulting in hypothyroidism or hyperthyroidism. Based on median urinary iodine concentrations, epidemiological criteria have been established for the categorization and monitoring of nutritional iodine status of a population (or subgroups of populations). Additional methods for iodine intake assessment include measurement of thyroid size (by thyroid...
Source: Thyroid Research - November 27, 2021 Category: Endocrinology Source Type: research

Poorly differentiated thyroid carcinoma arising from a lithium-induced goiter in a patient with schizophrenia: a case report
ConclusionsThyroid examination of psychiatric patients who develop goiter due to long-term lithium treatment should be monitored regularly, and appropriate investigations and surgery should be performed in a timely manner if the goiter is growing rapidly. (Source: Thyroid Research)
Source: Thyroid Research - November 19, 2021 Category: Endocrinology Source Type: research

Undetectable thyroglobulin makes 123I whole-body scan and stimulated thyroglobulin obsolete in follow-up care of differentiated thyroid cancer: a retrospective study
ConclusionsThis study shows that an undetectable high-sensitive Tg can change the management of patients with DTC and decrease the use and need of stimulated Tg and123I WBS. (Source: Thyroid Research)
Source: Thyroid Research - October 19, 2021 Category: Endocrinology Source Type: research

The relationship between thyroid function and ovarian reserve: a prospective cross-sectional study
AbstractBackgroundThyroid dysfunction can affect fertility and miscarriage risk by affecting the process of follicular growth, embryo development, implantation, and placental formation. It has been suggested that thyroid disorders are associated with ovarian reserve by affecting the follicular process. The aim of the present study was to investigate the relationship between thyroid hormone levels and ovarian reserve.MethodsThree hundred fourteen women with infertility due to various etiologies were enrolled in this study (172 individuals with Anti-Mullerian hormone (AMH) level  ≥ 1.1 ng/ml and 142 individuals with AMH
Source: Thyroid Research - October 1, 2021 Category: Endocrinology Source Type: research

Association between thyroid disorders and COVID-19: a protocol for a systematic review and meta-analysis
ConclusionResults of this study will provide current evidence on the association of COVID-19 diseases with any thyroid disorders such as hypothyroidism, thyrotoxicosis, and thyroid cancer with or without radioiodine therapy. Findings will be disseminated in peer-reviewed publications and conference presentations.Trial registration PROSPERO registration number: CRD42020184289.https://www.crd.york.ac.uk/PROSPERO/#recordDetails (Source: Thyroid Research)
Source: Thyroid Research - September 29, 2021 Category: Endocrinology Source Type: research

Recurrence of carcinoma showing thymus-like differentiation (CASTLE) involving the thyroid gland
ConclusionsCASTLE is a rare disease, diagnosed based on postoperative pathology and immunohistochemistry analysis, especially upon CD5 marker. In case of relapse, treatment options include surgery and radiotherapy; however conservative management without intervention is an acceptable alternative in some cases. (Source: Thyroid Research)
Source: Thyroid Research - August 16, 2021 Category: Endocrinology Source Type: research

Development of metastatic poorly differentiated thyroid cancer from a sub-centimeter papillary thyroid carcinoma in a young patient with a germline MET mutation – association or random chance?
ConclusionsThe question of whether the observedMET mutation in any way influenced the dedifferentiation of a primary PTC into a PDTC metastasis remains to be established. Moreover, our data corroborate earlier studies, indicating thatMET is aberrantly expressed in PTC and may influence the invasive behavior of these tumors. (Source: Thyroid Research)
Source: Thyroid Research - August 14, 2021 Category: Endocrinology Source Type: research

How to use thionamide anti-thyroid drug in the young – what’s new?
AbstractThe excess thyroid hormone secretion that characterises Graves ’ disease (GD) is generated when stimulatory antibodies bind to the thyroid stimulating hormone receptor on the follicular cell of the thyroid gland.This underlying mechanism cannot easily be abolished and the mainstay of Graves ’ disease (GD) management in the young remains thionamide anti-thyroid drug (ATD). Unfortunately, GD will usually recur after a 2 or 3 year course of ATD, even when the stimulatory antibody titres have fallen. The diagnosis of GD therefore usually signals the start of a lengthy period of out-patie nt assessments and ...
Source: Thyroid Research - July 21, 2021 Category: Endocrinology Source Type: research

Falsely diagnosed thyrotoxicosis caused by anti-streptavidin antibodies and pre-wash procedures
ConclusionsTo our knowledge, this is the first published report to clearly investigate such interferences using a combination of polyethylene glycol precipitation, heterophilic blocking tube precipitation, streptavidin-coated magnetic particle precipitation, and different instruments with or without pre-wash. Clinicians should consider that interferences caused by anti-streptavidin antibodies could lead to a misdiagnosis of thyrotoxicosis. Moreover, discussions between laboratory specialists, clinicians, and manufacturers are required to identify interferences and avoid unnecessary examinations and inappropriate treatment....
Source: Thyroid Research - July 10, 2021 Category: Endocrinology Source Type: research

Advanced thyroid carcinomas: neural network analysis of ultrasonographic characteristics
AbstractBackgroundUltrasound is the first-line imaging modality for detection and classification of thyroid nodules. Certain characteristics observable by ultrasound have recently been identified that may indicate malignancy. This retrospective cohort study was conducted to test the hypothesis that advanced thyroid carcinomas show distinctive clinical and sonographic characteristics. Using a neural network model as proof of concept, nine clinical/sonographic features served as input.MethodsAll 96 study enrollees had histologically confirmed thyroid carcinomas, categorized (n = 32, each) as follows: group 1, a...
Source: Thyroid Research - June 29, 2021 Category: Endocrinology Source Type: research

Papillary thyroid microcarcinoma with lung metastases: a case report and review of the literature
ConclusionsLymph node metastasis or extraglandular extension has been reported in the few published cases of metastatic PTMC, including the present case, and the average age of these cases was 58.8  ± 12.0 years. Although active surveillance without surgical resection is expected to become a standard of care for PTMC, this case indicates that a subset of PTMC patients with risk factors may develop distant metastases. Hence, careful preoperative screening is required to avoid complicatio ns associated with completion thyroidectomy. (Source: Thyroid Research)
Source: Thyroid Research - June 11, 2021 Category: Endocrinology Source Type: research

Associations between maternal urinary iodine assessment, dietary iodine intakes and neurodevelopmental outcomes in the child: a systematic review
AbstractObjectiveMild to moderate iodine deficiency during pregnancy has been associated with adverse neurodevelopmental outcomes in offspring. Few research studies to date combine assessment of urinary iodine (UIC and/or ICr), biomarkers that best reflect dietary intake, with reported dietary intake of iodine rich foods in their assessment of iodine deficiency. Thus, a systematic review was conducted to incorporate both these important measures.DesignUsing PRISMA guidelines, a comprehensive search was conducted in three electronic databases (EMBASE ®, MedLine® and Web of Science®) from January 1970–March...
Source: Thyroid Research - June 7, 2021 Category: Endocrinology Source Type: research

Determination of calcium and parathyroid hormone levels following hemithyroidectomy
ConclusionsAlthough serum calcium level decreased after a lobectomy, it always remained above 4  mg/dl. We conclude that hypocalcaemia is rare following hemithyroidectomy. (Source: Thyroid Research)
Source: Thyroid Research - June 3, 2021 Category: Endocrinology Source Type: research

The interrelationship between pregnancy, venous thromboembolism, and thyroid disease: a hypothesis-generating review
In conclusion, a normal pregnancy entails hormonal changes, which influence the onset of VTE and thyroid disease. Current evidence suggests an association between thyroid disease and VTE in non-pregnant individuals. This review proposes the hypothesis that maternal thyroid disease associates with VTE in pregnant women and call for future research studies on this subject. If an association exists in pregnant women specifically, such findings may have clinical implications regarding strategies for thyroid function testing and potential thromboprophylaxis in selected individuals. (Source: Thyroid Research)
Source: Thyroid Research - May 25, 2021 Category: Endocrinology Source Type: research

Risk factors for transient and permanent congenital hypothyroidism: a population-based case-control study
ConclusionFamily history, neonatal jaundice, gestational age at birth, and Betadine usage in pregnancy are associated with CH. (Source: Thyroid Research)
Source: Thyroid Research - May 5, 2021 Category: Endocrinology Source Type: research

Thyroid hemiagenesis with a TI-RADS 2 nodule in the contralateral lobe
ConclusionThyroid hemiagenesis is often associated with other thyroid disorders. Its diagnosis should prompt an active search for other associated morphological or functional thyroid abnormalities. (Source: Thyroid Research)
Source: Thyroid Research - April 30, 2021 Category: Endocrinology Source Type: research

A case of thyrotoxicosis-induced anemia in a patient with painless thyroiditis
We report the case of a patient with pancreatic diabetes who developed anemia caused by thyrotoxicosis due to painless thyroiditis.Case presentationThe patient was a 37-year-old man who visited the hospital complaining of fatigue, palpitations, and dyspnea. His hemoglobin was 110  g/l (reference range, 135–176), and mean corpuscular volume was 81.5 fl (81.7–101.6). His free thyroxine (FT4) was high, at 100.4 pmol/l (11.6–21.9); the free triiodothyronine (FT3) was high, at 27.49 pmol/l (3.53–6.14); TSH was low, at
Source: Thyroid Research - April 23, 2021 Category: Endocrinology Source Type: research

Clinical outcome of patients with differentiated thyroid cancer and raised antithyroglobulin antibody levels: a retrospective study
AbstractBackgroundThyroglobulin (Tg) is a specific tumor marker for differentiated thyroid cancer (DTC). However, in the presence of an antithyroglobulin antibody (TgAb), it becomes unreliable. The purpose of the study was to assess the long-term outcome of DTC patients with raised TgAb.MethodIn a retrospective study, we included patients with DTC who had raised TgAb following total thyroidectomy. We excluded patients with persistently raised Tg ( ≥ 1 ng/ml) or radioiodine avid disease. Serial TgAb levels, excellent response (ER), incomplete response (IR), and anatomical recurrence were evaluated.ResultsA total o...
Source: Thyroid Research - April 15, 2021 Category: Endocrinology Source Type: research

Prevalence of thyroid carcinoma in nodules with thy 3 cytology: the role of preoperative ultrasonography and strain elastography
ConclusionsIrregular margins, ill-defined borders, a taller than wide shape and low elasticity were associated with malignancy. Elastography should be performed when evaluating Thy3 nodules. (Source: Thyroid Research)
Source: Thyroid Research - April 9, 2021 Category: Endocrinology Source Type: research

Association between thyroid autoimmunity and ovarian reserve in women with hypothyroidism
ConclusionsNo significant alteration was found in the ovarian reserve of women with HT. (Source: Thyroid Research)
Source: Thyroid Research - March 22, 2021 Category: Endocrinology Source Type: research

Practice patterns and outcomes in the management of Thai patients with Graves ’ disease
ConclusionsOur present study highlighted the changing landscape of primary treatments for hyperthyroid GD toward ATD and the sharp downward trend in the surgical option. Even though ATD was associated with a low remission rate, it was preferred by many patients and physicians. The use of RAI as the primary treatment decreased in the last decade. However, RAI was a very effective treatment for Graves ’ hyperthyroidism but will inevitably induce hypothyroidism and a requirement for life-long replacement therapy. (Source: Thyroid Research)
Source: Thyroid Research - March 3, 2021 Category: Endocrinology Source Type: research

Pretibial myxedema in a euthyroid patient: a case report
ConclusionAbsence of history of thyroid disorder and normal thyroid function tests should not exclude the diagnosis of pretibial myxedema. (Source: Thyroid Research)
Source: Thyroid Research - March 1, 2021 Category: Endocrinology Source Type: research

Malignancy risk of hyperfunctioning thyroid nodules compared with non-toxic nodules: systematic review and a meta-analysis
ConclusionsOdds of malignancy of hot nodules is reduced compared with non-toxic nodules; however, the incidence of malignancy reported in hot nodules was higher than expected. These findings highlight the need for further studies into the malignancy risk of hot nodules. (Source: Thyroid Research)
Source: Thyroid Research - February 25, 2021 Category: Endocrinology Source Type: research

Factors affecting thyroid nodule fine needle aspiration non ‐diagnostic rates: a retrospective association study of 1975 thyroid biopsies
AbstractBackgroundThyroid nodules are common in clinical practice, and it is important to distinguish benign nodules, the vast majority, from malignant ones. Non-diagnostic (ND) samples have the potential to delay or mis-diagnose or lead to unnecessary surgeries, and it is important to examine what factors influence the ND rate. Prior literature has suggested that the impact of bedside cytology on ND rate is dependent on the initial adequacy rate, whereby higher ND rates benefit most from bedside cytology. We aim to compare the impact of bedside adequacy review between specialist groups who perform high volume thyroid biop...
Source: Thyroid Research - February 10, 2021 Category: Endocrinology Source Type: research

Hyperthyroidism in gestational trophoblastic disease – a literature review
ConclusionEarly detection of GTD is critical to prevent development of hyperthyroidism and its associated complications. Hyperthyroidism should be recognised as an important perioperative consideration for women undergoing surgery for GTD, and requires appropriate management. Future studies should explore risk factors for hyperthyroidism in GTD, which may facilitate earlier identification of high-risk women. (Source: Thyroid Research)
Source: Thyroid Research - January 14, 2021 Category: Endocrinology Source Type: research

Recent advances in the management of anaplastic thyroid cancer
AbstractAnaplastic thyroid cancer (ATC) is undoubtedly the thyroid cancer histotype with the poorest prognosis. The conventional treatment includes surgery, radiotherapy, and conventional chemotherapy. Surgery should be as complete as possible, securing the airway and ensuring access for nutritional support; the current standard of care of radiotherapy is the intensity-modulated radiation therapy; chemotherapy includes the use of doxorubicin or taxanes (paclitaxel or docetaxel) generally with platin (cisplatin or carboplatin). However, frequently, these treatments are not sufficient and a systemic treatment with kinase inh...
Source: Thyroid Research - November 24, 2020 Category: Endocrinology Source Type: research

Selenium and at-risk pregnancy: challenges and controversies
AbstractSelenium (Se), an essential trace element, is inserted as selenocysteine into an array of functional proteins and forms the core of various enzymes that play a cardinal role in antioxidant defense mechanisms, in redox regulation, and in thyroid hormone metabolism. Variations in plasma Se are due to nutritional habits, geographic and ethnic differences, and probably to genetic polymorphisms, the latter still to be conclusively established. Se concentrations were reported to be low in women of reproductive age in the UK, decreasing further during pregnancy, this resulting in low plasma and placental antioxidant enzym...
Source: Thyroid Research - September 30, 2020 Category: Endocrinology Source Type: research

Can we safely reduce the administration of 131-iodine in patients with differentiated thyroid cancer? – experience of the Brugmann hospital in Brussels
AbstractBackground131-iodine (131I) administration after surgery remains a standard practice in differentiated thyroid cancer (DTC). In 2014, the American Thyroid Association presented new guidelines for the staging and management of DTC, including no systematic131I in patients at low-risk of recurrence and a reduced131I activity in intermediate risk.The present study aims at evaluating the rate of response to treatment following this new therapeutic management compared to our previous treatment strategy in patients with DTC of different risks of recurrence.MethodsPatients treated and followed up for DTC according to the 2...
Source: Thyroid Research - September 11, 2020 Category: Endocrinology Source Type: research

Total T4 rise in pregnancy: a relook?
AbstractBackgroundTotal T4 (TT4) measurement is preferred to free T4 (FT4) especially in last part of pregnancy. Guidelines by American Thyroid Association, European Thyroid Association and Endocrine Society state that TT4 increases 1.5 times pre-pregnant levels after week 16 of pregnancy. However, this is based on a small study conducted 40  years ago which used radioimmunoassay for determination in changes in TT4.Materials and methodsA cross-sectional study was undertaken to find reference interval for thyroid function in different trimester of pregnancy with special reference to look at the degree of elevation of...
Source: Thyroid Research - July 30, 2020 Category: Endocrinology Source Type: research

Kinetic analysis of the growth rate of sporadic and hereditary medullary thyroid carcinoma: comparing the postoperative calcitonin-doubling rate with the hypothetical preoperative tumor volume-doubling rate
AbstractBackgroundOur previous kinetic analyses of changes in the tumor volume (TV) of papillary thyroid microcarcinomas during active surveillance revealed that the tumors ’ growth varied over time from rather rapid growth to shrinkage and that the hypothetical TV-doubling rates (DRs) before the patients’ presentation were much larger than their observed TV-DRs, indicating that rapid growth phases preceded their presentation. Whether this phenomenon also occurs in medullary thyroid carcinoma (MTC) was unknown.MethodsWe retrospectively analyzed the cases of 46 MTC patients (18 hereditary, 28 sporadic; 9 –...
Source: Thyroid Research - July 20, 2020 Category: Endocrinology Source Type: research

Teprotumumab: a disease modifying treatment for graves ’ orbitopathy
ConclusionsThe results from these two large clinical trials have shown teprotumumab to have remarkable effects on multiple clinical outcomes in GO, particularly in its ability to reverse proptosis. It may herald a new era in the treatment of thyroid eye disease and could offer an alternative to surgery and its associated complications. Additional studies will continue to shape the treatment of GO and define the role of teprotumumab within the treatment paradigm. (Source: Thyroid Research)
Source: Thyroid Research - July 3, 2020 Category: Endocrinology Source Type: research

Antithyroid drugs and birth defects
AbstractAntithyroid drugs (ATDs) are preferred for the treatment of hyperthyroidism caused by Graves ’ disease in pregnant women. The drugs have been a recognized treatment for decades, and a general risk of side effects is known. For the use of ATDs in pregnancy, a concern about teratogenic side effects has been brought forward since the 1970s. In more recent years, a number of large observation al studies have added new evidence and quantified the risk of birth defects associated with different types of ATDs. The findings that both Methimazole (MMI) and Propylthiouracil (PTU) are associated with birth defects have ...
Source: Thyroid Research - June 26, 2020 Category: Endocrinology Source Type: research

Elevated serum TSH concentrations are associated with higher BMI Z-scores in southern Iranian children and adolescents
ConclusionBMI Z-score and elevated TSH levels are positively correlated however studies should be performed on establishing the causality. (Source: Thyroid Research)
Source: Thyroid Research - June 12, 2020 Category: Endocrinology Source Type: research

Macrofollicular variant of papillary thyroid carcinoma with metastasis to femur
ConclusionsOur case supports the view that, on rare ocassions, MFV-PTC may show a more aggressive biological behavior than expected. The synchronous or asynchronous presence of one or more bone lesions, should raise the suspicion of metastasis. Given the suspicion, it is necessary to take a biopsy to confirm histologically. Only a careful analysis of the architectural and cytological characteristics of goiter or hyperplastic nodules will allow to recognize this rare variety of carcinoma. (Source: Thyroid Research)
Source: Thyroid Research - June 12, 2020 Category: Endocrinology Source Type: research

Thyroid cancer among patients with thyroid nodules in Yemen: a three-year retrospective study in a tertiary center and a specialty clinic
ConclusionThyroid cancer has a higher prevalence in Yemen than in other middle eastern countries. Our study also reports a higher rate of follicular thyroid cancer than that in other published data, which has to be confirmed by further studies. The malignancy and premalignant diagnosis rate was ~ 50% in our patients who underwent surgery. Many centers in Yemen still do not perform FNA before thyroid surgery. It is important that other centers in the country start emphasizing the need for FNA before surgery. This will decrease the number of unnecessary surgeries and associated complications. (Source: Thyroid Research)
Source: Thyroid Research - June 5, 2020 Category: Endocrinology Source Type: research

Nice guideline on thyroid disease: where does it take us with liothyronine?
AbstractThe new NICE guidelines on thyroid disease and its management do not recommend the routine use of liothyronine, but do not completely rule it out either. Guidelines from the British and European Thyroid Associations are open to a “trial of liothyronine” on an individual basis.Some patients do not feel well on L-thyroxine despite a serum TSH in the reference range. Key issues to consider in such patients include establishing whether the patient had established hypothyroidism initially, and whether the L-thyroxine has been titrated carefully enough, possibly using small increments, to achieve a careful ba...
Source: Thyroid Research - May 22, 2020 Category: Endocrinology Source Type: research

The effectiveness of cognitive- behavioral therapy on quality of life in women with hypothyroidism in the reproductive age: a randomized controlled trial
This study aimed to evaluate the effect of cognitive- behavioral therapy (CBT) on the quality of life in women with hypothyroidism.Methods96 women with hypothyroidism randomly allocated into two groups: CBT group (n = 48) and control group (n = 48). Women in the CBT group were classified into four sub-groups of 12, and each sub-group received eight sessions of counseling (each session lasting 90 min). We collected data using a demographic questionnaire and the 36-Item Short Form Health Survey (SF 36) for measuring the quality of life. We used the independent t-test, chi-square test and AN...
Source: Thyroid Research - May 19, 2020 Category: Endocrinology Source Type: research

Adequate timing and constant supervision are the keys for successful implementation of levothyroxine or levothyroxine/paracetamol absorption test
ConclusionsAdequate patient supervision and frequent sampling (e.g. every 30  min for 210 min) is the key for successful implementation of LT4 absorption test. Paracetamol coadministration appears superfluous in such cases. (Source: Thyroid Research)
Source: Thyroid Research - May 17, 2020 Category: Endocrinology Source Type: research

Time-dependent changes in FT4 and FT3 levels measured using mass spectrometry after an acute ingestion of excess levothyroxine in a case with hypothyroidism
ConclusionIt was helpful to clarify the time dependent changes in free thyroid hormone levels by ultrafiltration LC-MS/MS in discussing the clinical course in this case. Though mass spectrometry has a disadvantage in speed for routine laboratory use, its accurate measurement, particularly of levels exceeding the measurable range of the immunoassay, provides valuable information for more appropriate management of extreme thyrotoxicosis. (Source: Thyroid Research)
Source: Thyroid Research - April 30, 2020 Category: Endocrinology Source Type: research

Should radioiodine now be first line treatment for Graves ’ disease?
ConclusionsEarly radioiodine treatment will potentially reduce mortality and should be offered to patients with severe disease. However, thionamides are still suitable for patients with milder disease, contraindications to radioiodine, or individuals who choose to avoid permanent hypothyroidism. Ultimately, a patient individualised approach that prioritises early and  sustained control of hyperthyroidism will improve long-term outcomes regardless of the therapy modality used. (Source: Thyroid Research)
Source: Thyroid Research - March 8, 2020 Category: Endocrinology Source Type: research

Falsely undetectable TSH in a euthyroid patient
ConclusionIf the result of TSH level revealed very low or undetectable through one specific method, it should not be considered necessarily as a symptom of hyperthyroidism. It is to be requested to measure by the other methods with other devices too. (Source: Thyroid Research)
Source: Thyroid Research - January 29, 2020 Category: Endocrinology Source Type: research

Cross-sectional and prospective study on anti-M üllerian hormone changes in a cohort of pre-menopausal women with a history of differentiated thyroid cancer
ConclusionsAMH can be considered a reliable index of ovarian reserve in women with DTC. Chronological age is the main factor influencing AMH levels in both DTC patients and controls. After age-related stratification, AMH levels are similar in women with DTC treated with RAI and those treated with surgery alone. (Source: Thyroid Research)
Source: Thyroid Research - January 9, 2020 Category: Endocrinology Source Type: research

Life-threatening complications of high doses of intravenous methylprednisolone for treatment of Graves ’ orbitopathy
ConclusionsAn individualized safe and effective dose of intravenous methylprednisolone should be established for each patient with GO based on the vascular risk factors, comorbidities, and concomitant drugs. According to the European Group on Graves ’ Orbitopathy (EUGOGO) guidelines, cumulative doses of intravenous methylprednisolone should not exceed 8 g. (Source: Thyroid Research)
Source: Thyroid Research - December 22, 2019 Category: Endocrinology Source Type: research

Pre-sternal thyroid swellings: a case of rare aberrant site recurrence and review of literature
ConclusionPre-sternal region masses of thyroid origin are very rare. A proper work up, suspicion for thyroid mass and array of tests will be required to come to a provisional diagnosis. Since the masses reported in literature were primarily malignant, any such mass may be treated on lines of malignancy with radical surgery. (Source: Thyroid Research)
Source: Thyroid Research - November 20, 2019 Category: Endocrinology Source Type: research

Meeting Abstracts from the 67 th Annual British Thyroid Association Meeting
(Source: Thyroid Research)
Source: Thyroid Research - November 18, 2019 Category: Endocrinology Source Type: research

The surgical management of locally advanced well-differentiated thyroid carcinoma: changes over the years according to the AJCC 8th edition Cancer Staging Manual
ConclusionsWe discuss the changes introduced by the 8th edition AJCC Cancer Staging Manual, in terms of the diagnostic and surgical management of extra thyroid extension, in patients affected by papillary and follicular thyroid cancer. (Source: Thyroid Research)
Source: Thyroid Research - October 26, 2019 Category: Endocrinology Source Type: research

Association of thyroid hormones with resting energy expenditure and complement C3 in normal weight high body fat women
This study aims to examine the relationship between adiposity, thyroid hormone levels and immunity by comparing resting energy expenditure (REE), serum thyroid hormone levels and complement C3 in normal-weight high body fat (normal weight obesity) women and normal-weight normal body fat women.MethodsIn this case-control study, 40 women with normal body weight (BMI
Source: Thyroid Research - October 24, 2019 Category: Endocrinology Source Type: research

Painless destructive thyroiditis in a patient with resistance to thyroid hormone: a case report
We report a case of painless thyroiditis in a patient with RTH that was misdiagnosed as Graves ’ disease because of TSH-suppressed thyrotoxicosis.Case presentationA sixteen-year-old boy consulted a local general physician for fatigue. He had a goiter, and biochemical analysis showed TSH  
Source: Thyroid Research - October 24, 2019 Category: Endocrinology Source Type: research