Benefit of lifestyle-based T2DM prevention is influenced by prediabetes phenotype
Nature Reviews Endocrinology, Published online: 14 February 2020; doi:10.1038/s41574-019-0316-1Prediabetes phenotype can influence the effectiveness of lifestyle intervention-based diabetes prevention programmes. This Perspectives suggests that diabetes prevention programmes are not effective in individuals with isolated impaired fasting glucose and calls for further research to improve prevention of type 2 diabetes mellitus in this population. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - February 14, 2020 Category: Endocrinology Authors: Matthew D. Campbell Thirunavukkarasu Sathish Paul Z. Zimmet Kavumpurathu R. Thankappan Brian Oldenburg David R. Owens Jonathan E. Shaw Robyn J. Tapp Source Type: research

The role of ceramides in metabolic disorders: when size and localization matters
Nature Reviews Endocrinology, Published online: 14 February 2020; doi:10.1038/s41574-020-0320-5This Review examines the emerging concept that distinct ceramide species in specific cellular compartments can exert specialized functions in obesity-associated deterioration of metabolic homeostasis. Ceramides are therefore potential targets in the development of novel and specific therapies for obesity and obesity-associated diseases. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - February 14, 2020 Category: Endocrinology Authors: Sarah M. Turpin-Nolan Jens C. Br üning Source Type: research

Food as a circadian time cue — evidence from human studies
Nature Reviews Endocrinology, Published online: 13 February 2020; doi:10.1038/s41574-020-0318-zFood is widely assumed to be a zeitgeber, or time cue, for the human circadian system; however, evidence from human trials is scarce. This Review highlights evidence from human studies that food is a zeitgeber and compares findings against formal zeitgeber criteria. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - February 13, 2020 Category: Endocrinology Authors: Philip Lewis Henrik Oster Horst W. Korf Russell G. Foster Thomas C. Erren Source Type: research

A predictive CD8+ T cell phenotype for T1DM progression
Nature Reviews Endocrinology, Published online: 12 February 2020; doi:10.1038/s41574-020-0330-3In a cross-sectional study of individuals with type 1 diabetes mellitus, those who were designated to be slow disease progressors had an increased proportion of autoreactive, islet-specific CD8+ T cells expressing an ‘exhausted’ phenotype. By contrast, rapid disease progressors had increased numbers of islet-specific CD8+ T cells with a transitional memory phenotype. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - February 12, 2020 Category: Endocrinology Authors: F. Susan Wong Li Wen Source Type: research

Recognizing hypoxia in phaeochromocytomas and paragangliomas
Nature Reviews Endocrinology, Published online: 11 February 2020; doi:10.1038/s41574-020-0324-1Studies uncovering the cellular mechanisms of adaptation to varying oxygen levels were recognized with the 2019 Nobel Prize in Physiology or Medicine. Here, we focus on the remarkable parallels between the pathways regulating oxygen availability and those driving rare neuroendocrine tumours, phaeochromocytomas and paragangliomas, and discuss the translational implications of this connection. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - February 11, 2020 Category: Endocrinology Authors: Patricia L. M. Dahia Rodrigo A. Toledo Source Type: research

New aspects of vitamin D metabolism and action — addressing the skin as source and target
Nature Reviews Endocrinology, Published online: 06 February 2020; doi:10.1038/s41574-019-0312-5This Review provides an overview of vitamin D production in the skin. The regulation of wound healing and hair growth by vitamin D are also discussed. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - February 6, 2020 Category: Endocrinology Authors: Daniel Bikle Sylvia Christakos Source Type: research

Waist circumference as a vital sign in clinical practice: a Consensus Statement from the IAS and ICCR Working Group on Visceral Obesity
Nature Reviews Endocrinology, Published online: 04 February 2020; doi:10.1038/s41574-019-0310-7In this Consensus Statement, the International Atherosclerosis Society and International Chair on Cardiometabolic Risk Working Group on Visceral Obesity recommend that waist circumference be included routinely as a measurement in clinical practice. They summarize the evidence that waist circumference and BMI together can provide improved assessments of cardiometabolic risk compared with either measurement alone. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - February 4, 2020 Category: Endocrinology Authors: Robert Ross Ian J. Neeland Shizuya Yamashita Iris Shai Jaap Seidell Paolo Magni Raul D. Santos Benoit Arsenault Ada Cuevas Frank B. Hu Bruce A. Griffin Alberto Zambon Philip Barter Jean-Charles Fruchart Robert H. Eckel Yuji Matsuzawa Jean-Pierre Despr és Source Type: research

Levothyroxine treatment and cholesterol in hypothyroidism
Nature Reviews Endocrinology, Published online: 31 January 2020; doi:10.1038/s41574-020-0323-2Thyroid status and serum cholesterol levels are intimately linked. Hypothyroidism causes hypercholesterolaemia, which is thought to be resolved after treatment with levothyroxine and normalization of thyroid-stimulating hormone. However, some studies indicate that hypercholesterolaemia persists despite treatment, requiring more frequent use of statins. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - January 31, 2020 Category: Endocrinology Authors: Antonio C Bianco Peter Taylor Source Type: research

Selenium in thyroid disorders — essential knowledge for clinicians
Nature Reviews Endocrinology, Published online: 30 January 2020; doi:10.1038/s41574-019-0311-6Selenium status varies across the world and adverse health effects have been observed at both extremes of intake. This Review discusses the physiological functions of selenium and highlights evidence that selenium status is important in thyroid function. The evidence for selenium supplementation from randomized clinical trials in benign thyroid diseases is also considered. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - January 30, 2020 Category: Endocrinology Authors: Kristian Hillert Winther Margaret Philomena Rayman Steen Joop Bonnema Laszlo Heged üs Source Type: research

Ketogenic diet affects immune cells in mice
Nature Reviews Endocrinology, Published online: 30 January 2020; doi:10.1038/s41574-020-0328-xKetogenic diet affects immune cells in mice (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - January 30, 2020 Category: Endocrinology Authors: Claire Greenhill Source Type: research

Electronic health records to predict GDM
Nature Reviews Endocrinology, Published online: 29 January 2020; doi:10.1038/s41574-020-0326-zElectronic health records to predict GDM (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - January 29, 2020 Category: Endocrinology Authors: Anna Kriebs Source Type: research

A mitochondrial root to accelerated ageing and frailty
Nature Reviews Endocrinology, Published online: 28 January 2020; doi:10.1038/s41574-020-0319-yA discovery metabolomic study was performed in a large cohort of adults to identify circulating biomarkers of frailty. The study found that carnitine and vitamin E pathways were dysregulated in frail compared with non-frail participants. These findings point to dysregulated mitochondrial metabolism as a potential root of age-related frailty. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - January 28, 2020 Category: Endocrinology Authors: Luigi Ferrucci Marta Zampino Source Type: research

Advances in GDF15 research
Nature Reviews Endocrinology, Published online: 27 January 2020; doi:10.1038/s41574-020-0327-yAdvances in GDF15 research (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - January 27, 2020 Category: Endocrinology Authors: Alan Morris Source Type: research

The re-emergence of adipose innervation as a research focus
Nature Reviews Endocrinology, Published online: 24 January 2020; doi:10.1038/s41574-020-0322-3In the pursuit of understanding metabolic control and energy balance, peripheral nerve communication between adipose tissues and the brain has been largely ignored. This Comment discusses the need for additional research that focuses on the role of adipose peripheral nerve function in the maintenance of energy balance. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - January 24, 2020 Category: Endocrinology Authors: Kristy L. Townsend Source Type: research

Role of thyroid hormones in craniofacial development
This article discusses the role of thyroid hormones in craniofacial bone formation. The clinical consequences of thyroid hormone excess and deficiency are also outlined. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - January 23, 2020 Category: Endocrinology Authors: Victoria D. Leitch J. H. Duncan Bassett Graham R. Williams Source Type: research

Obesity-linked inflammation tied to glutamine levels
Nature Reviews Endocrinology, Published online: 20 January 2020; doi:10.1038/s41574-020-0321-4Obesity-linked inflammation tied to glutamine levels (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - January 20, 2020 Category: Endocrinology Authors: Shimona Starling Source Type: research

IGFs potential biomarkers for type 1 diabetes mellitus
Nature Reviews Endocrinology, Published online: 06 January 2020; doi:10.1038/s41574-020-0317-0IGFs potential biomarkers for type 1 diabetes mellitus (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - January 6, 2020 Category: Endocrinology Authors: Claire Greenhill Source Type: research

New insights into the pathogenesis and nonsurgical management of Graves orbitopathy
Nature Reviews Endocrinology, Published online: 30 December 2019; doi:10.1038/s41574-019-0305-4Graves orbitopathy has a negative impact on a patient’s quality of life. This Review provides an overview of the field and outlines the optimal management of Graves orbitopathy. The authors also highlight future research questions to direct future clinical trials. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - December 30, 2019 Category: Endocrinology Authors: Peter N. Taylor Lei Zhang Richard W. J. Lee Ilaria Muller Daniel G. Ezra Colin M. Dayan George J. Kahaly Marian Ludgate Source Type: research

Metformin-induced hepatokine reduces appetite
Nature Reviews Endocrinology, Published online: 23 December 2019; doi:10.1038/s41574-019-0315-2Metformin-induced hepatokine reduces appetite (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - December 23, 2019 Category: Endocrinology Authors: Shimona Starling Source Type: research

Transgenerational effects of polycystic ovary syndrome identified
Nature Reviews Endocrinology, Published online: 23 December 2019; doi:10.1038/s41574-019-0314-3Transgenerational effects of polycystic ovary syndrome identified (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - December 23, 2019 Category: Endocrinology Authors: Alan Morris Source Type: research

The benefits of time-restricted eating
Nature Reviews Endocrinology, Published online: 18 December 2019; doi:10.1038/s41574-019-0313-4The benefits of time-restricted eating (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - December 18, 2019 Category: Endocrinology Authors: Anna Kriebs Source Type: research

The role of macrophages in obesity-associated islet inflammation and β-cell abnormalities
Nature Reviews Endocrinology, Published online: 13 December 2019; doi:10.1038/s41574-019-0286-3The dominant immune cell type causing pancreatic islet inflammation in individuals with obesity and/or type 2 diabetes mellitus is the macrophage. In this Review, we focus on the characteristics of inflammation in obese or type 2 diabetes mellitus islets and the consequences of this with respect to β-cell function. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - December 13, 2019 Category: Endocrinology Authors: Wei Ying Wenxian Fu Yun Sok Lee Jerrold M. Olefsky Source Type: research

Harnessing heterogeneity in type 2 diabetes mellitus
Nature Reviews Endocrinology, Published online: 12 December 2019; doi:10.1038/s41574-019-0308-1Personalized, or precision, medicine in type 2 diabetes mellitus is becoming a reality with new insights into the contributions of subgroup analyses. The roadmap to future implementation must take into account individual and subgroup variability in genetic architecture, environment, clinical measures, lifestyle, cost-effectiveness and treatment burden. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - December 12, 2019 Category: Endocrinology Authors: Louis H. Philipson Source Type: research

Therapeutic breakthroughs for metastatic thyroid cancer
Nature Reviews Endocrinology, Published online: 09 December 2019; doi:10.1038/s41574-019-0307-2Multikinase inhibitors are effective treatments for thyroid cancers, acting primarily as antiangiogenic agents. This year, advances have been made in selective targeting of RET and BRAF in patients with medullary and anaplastic thyroid cancers, respectively. However, Hürthle cell carcinomas have a unique genomic landscape with no dominant truncal drivers, precluding simplistic approaches to therapeutic targeting. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - December 9, 2019 Category: Endocrinology Authors: Vera Tiedje James A. Fagin Source Type: research

Pulsatile GABA secretion by β-cells
Nature Reviews Endocrinology, Published online: 06 December 2019; doi:10.1038/s41574-019-0306-3Pulsatile GABA secretion by β-cells (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - December 6, 2019 Category: Endocrinology Authors: Shimona Starling Source Type: research

Gut microbiome influences exercise response
Nature Reviews Endocrinology, Published online: 04 December 2019; doi:10.1038/s41574-019-0309-0Gut microbiome influences exercise response (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - December 4, 2019 Category: Endocrinology Authors: Claire Greenhill Source Type: research

Sex differences in circadian misalignment
Nature Reviews Endocrinology, Published online: 02 December 2019; doi:10.1038/s41574-019-0303-6Sex differences in circadian misalignment (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - December 2, 2019 Category: Endocrinology Authors: Alan Morris Source Type: research

A road map for understanding molecular and genetic determinants of osteoporosis
Nature Reviews Endocrinology, Published online: 02 December 2019; doi:10.1038/s41574-019-0282-7In this Review, the authors highlight findings from genome-wide association studies and studies using various omics technologies individually to identify mechanisms of osteoporosis, which is a highly heritable condition. They also summarize current studies of data integration to understand, diagnose and inform the treatment of osteoporosis. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - December 2, 2019 Category: Endocrinology Authors: Tie-Lin Yang Hui Shen Anqi Liu Shan-Shan Dong Lei Zhang Fei-Yan Deng Qi Zhao Hong-Wen Deng Source Type: research

Reply to ‘Chinese famine and the diabetes mellitus epidemic’
Nature Reviews Endocrinology, Published online: 02 December 2019; doi:10.1038/s41574-019-0301-8Reply to ‘Chinese famine and the diabetes mellitus epidemic’ (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - December 2, 2019 Category: Endocrinology Authors: Chihua Li Elmar W. Tobi Bastiaan T. Heijmans L. H. Lumey Source Type: research

Chinese Famine and the diabetes mellitus epidemic
Nature Reviews Endocrinology, Published online: 02 December 2019; doi:10.1038/s41574-019-0300-9Chinese Famine and the diabetes mellitus epidemic (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - December 2, 2019 Category: Endocrinology Authors: Paul Zimmet Zumin Shi Assam El-Osta Linong Ji Source Type: research

Turning the tables on obesity: young people, IT and social movements
Nature Reviews Endocrinology, Published online: 29 November 2019; doi:10.1038/s41574-019-0288-1In this Perspectives, Lean and colleagues discuss harnessing social movements to address the obesity epidemic. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - November 29, 2019 Category: Endocrinology Authors: Charoula K. Nikolaou Thomas N. Robinson Kyra A. Sim Michael E. J. Lean Source Type: research

Reply to ‘Early-life exposure to the Chinese Famine and subsequent T2DM’
Nature Reviews Endocrinology, Published online: 29 November 2019; doi:10.1038/s41574-019-0302-7Reply to ‘Early-life exposure to the Chinese Famine and subsequent T2DM’ (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - November 29, 2019 Category: Endocrinology Authors: Chihua Li Elmar W. Tobi Bastiaan T. Heijmans L. H. Lumey Source Type: research

Early-life exposure to the Chinese Famine and subsequent T2DM
Nature Reviews Endocrinology, Published online: 29 November 2019; doi:10.1038/s41574-019-0299-yEarly-life exposure to the Chinese Famine and subsequent T2DM (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - November 29, 2019 Category: Endocrinology Authors: Zhiyong Zou Changwei Li George C. Patton Source Type: research

The effects of growth hormone on adipose tissue: old observations, new mechanisms
Nature Reviews Endocrinology, Published online: 28 November 2019; doi:10.1038/s41574-019-0280-9This Review provides an up-to-date overview of the lipolytic effects of growth hormone (GH), setting current knowledge into the context of historical data. In addition, the molecular mechanisms of GH-induced lipolysis and insulin resistance as well as the actions of GH on different adipose tissue depots and adipocyte subsets are discussed. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - November 28, 2019 Category: Endocrinology Authors: John J. Kopchick Darlene E. Berryman Vishwajeet Puri Kevin Y. Lee Jens O. L. Jorgensen Source Type: research

Obesity: a neuroimmunometabolic perspective
Nature Reviews Endocrinology, Published online: 27 November 2019; doi:10.1038/s41574-019-0283-6This Review provides an overview of the extensive crosstalk between adipocytes, resident innate immune cells and the sympathetic nerves that innervate adipose tissue, as well as the changes that occur in these secretory and signalling pathways in obesity. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - November 27, 2019 Category: Endocrinology Authors: Chelsea M. Larabee Oliver C. Neely Ana I. Domingos Source Type: research

Integrated pathways that control stress and energy homeostasis
Nature Reviews Endocrinology, Published online: 26 November 2019; doi:10.1038/s41574-019-0298-zFeeding is regulated by defined neuronal pathways and circulating factors that ensure homeostatic balance is maintained. However, many emotion-affective pathways are also involved in communicating positive and negative valence on feeding behaviour. In 2019, several seminal discoveries were made that illuminate the complex interaction between homeostatic and hedonic feeding control mechanisms. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - November 26, 2019 Category: Endocrinology Authors: Herbert Herzog Source Type: research

Diet reprogrammes glucocorticoid rhythms
Nature Reviews Endocrinology, Published online: 21 November 2019; doi:10.1038/s41574-019-0297-0Diet reprogrammes glucocorticoid rhythms (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - November 21, 2019 Category: Endocrinology Authors: Shimona Starling Source Type: research

The islets of Langerhans continue to reveal their secrets
Nature Reviews Endocrinology, Published online: 18 November 2019; doi:10.1038/s41574-019-0296-1Pancreatic islets, which are critical for glucose homeostasis, are endocrine microorgans embedded in the exocrine pancreas; their location has often limited studying their function. In 2019, advances in islet biology were achieved with new technologies extending findings from several decades ago and with conceptual advances built on findings from other fields. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - November 18, 2019 Category: Endocrinology Authors: Susan Bonner-Weir Source Type: research

A word of caution against excessive protein intake
Nature Reviews Endocrinology, Published online: 14 November 2019; doi:10.1038/s41574-019-0274-7Although dietary protein is crucial for human health, excessively high protein intake could have negative health consequences. This Perspective serves as a word of caution against the trend of protein-enriched diets and provides an evidence-based counterpoint that underscores the potential adverse public health consequences of high protein intake. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - November 14, 2019 Category: Endocrinology Authors: Bettina Mittendorfer Samuel Klein Luigi Fontana Source Type: research

Incidence and determinants of mental health service use after bariatric surgery
Nature Reviews Endocrinology, Published online: 14 November 2019; doi:10.1038/s41574-019-0292-5Bariatric surgery results in sustained weight loss and improvement in many obesity-related comorbidities. However, the effects of bariatric surgery on long-term mental health are less clear. A recent longitudinal cohort study shows that patients undergoing bariatric surgery seek mental health services at higher rates after surgery than before surgery and identifies specific risk factors for increased psychiatric service use. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - November 14, 2019 Category: Endocrinology Authors: Sanjeev Sockalingam Source Type: research

Microbiota and muscle highway — two way traffic
Nature Reviews Endocrinology, Published online: 14 November 2019; doi:10.1038/s41574-019-0291-6Exercise is a potent modulator of intestinal microbiota composition and function. In 2019, several studies uncovered biologically important links between skeletal muscle and the gut microbiota, revealing how the gut bacteria respond to an exercise challenge and have reciprocal roles in fuel availability, muscle function and endurance performance. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - November 14, 2019 Category: Endocrinology Authors: John A. Hawley Source Type: research

Sex-dependent link between circadian misalignment and adiposity
Nature Reviews Endocrinology, Published online: 13 November 2019; doi:10.1038/s41574-019-0293-4A cross-sectional study shows that proxies of circadian misalignment, such as late chronotype and social jet lag, are associated with increased adiposity in adolescent girls but not adolescent boys, highlighting a potential sex-specific effect of circadian misalignment. Interventions targeting sleep timing should be considered in the prevention of adolescent obesity. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - November 13, 2019 Category: Endocrinology Authors: Jingyi Qian Frank A. J. L. Scheer Source Type: research

Dietary restriction in old age does not extend life
Nature Reviews Endocrinology, Published online: 13 November 2019; doi:10.1038/s41574-019-0295-2Dietary restriction in old age does not extend life (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - November 13, 2019 Category: Endocrinology Authors: Anna Kriebs Source Type: research

Consensus on the key characteristics of endocrine-disrupting chemicals as a basis for hazard identification
Nature Reviews Endocrinology, Published online: 12 November 2019; doi:10.1038/s41574-019-0273-8In this Expert Consensus Statement, the authors define 10 key characteristics (KCs) for endocrine-disrupting chemicals. They further describe the logic by which these KCs are identified and the assays that could be used to assess several of these KCs. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - November 12, 2019 Category: Endocrinology Authors: Michele A. La Merrill Laura N. Vandenberg Martyn T. Smith William Goodson Patience Browne Heather B. Patisaul Kathryn Z. Guyton Andreas Kortenkamp Vincent J. Cogliano Tracey J. Woodruff Linda Rieswijk Hideko Sone Kenneth S. Korach Andrea C. Gore Lauren Ze Source Type: research

Two drugs are better than one to start T2DM therapy
Nature Reviews Endocrinology, Published online: 08 November 2019; doi:10.1038/s41574-019-0294-3Early and intensive glycaemic control protects patients with type 2 diabetes mellitus (T2DM) from the development of late cardiovascular complications. The authors of the VERIFY trial now show that a more durable attainment of HbA1c  (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - November 8, 2019 Category: Endocrinology Authors: Francesco Prattichizzo Lucia La Sala Antonio Ceriello Source Type: research

Trafficking machinery regulates metabolism
Nature Reviews Endocrinology, Published online: 04 November 2019; doi:10.1038/s41574-019-0290-7Trafficking machinery regulates metabolism (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - November 4, 2019 Category: Endocrinology Authors: Shimona Starling Source Type: research

Identifying the waist circumference of risk in people of African descent
Nature Reviews Endocrinology, Published online: 01 November 2019; doi:10.1038/s41574-019-0289-0The relationship between type 2 diabetes mellitus (T2DM), insulin resistance and central obesity is not uniformly applicable to populations worldwide. In this Comment, we discuss the challenge of establishing waist circumference thresholds to predict T2DM in Africa. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - November 1, 2019 Category: Endocrinology Authors: Anne E. Sumner Mohammad Hadi Bagheri Source Type: research

Author Correction: Reproductive hazards of space travel in women and men
Nature Reviews Endocrinology, Published online: 30 October 2019; doi:10.1038/s41574-019-0287-2Author Correction: Reproductive hazards of space travel in women and men (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - October 30, 2019 Category: Endocrinology Authors: Birendra Mishra Ulrike Luderer Source Type: research

Linking nicotine addiction and T2DM
Nature Reviews Endocrinology, Published online: 28 October 2019; doi:10.1038/s41574-019-0285-4Linking nicotine addiction and T2DM (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - October 28, 2019 Category: Endocrinology Authors: Alan Morris Source Type: research

Gamification and social incentives increase physical activity
Nature Reviews Endocrinology, Published online: 25 October 2019; doi:10.1038/s41574-019-0281-8A nationwide study conducted in the USA demonstrated that an intervention combining gamification with social incentives, conducted within the context of a behavioural economics platform, can result in a moderate yet significant increase in physical activity in adults with obesity over a period of 24 weeks with an additional 12 week follow-up. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - October 25, 2019 Category: Endocrinology Authors: John M. Jakicic Renee J. Rogers Source Type: research