Poor Increase in Pulse Pressure During Cardiopulmonary Exercise Testing Predicts Cardiovascular Death of Patients With Heart Failure With Reduced Ejection Fraction.
Abstract BACKGROUND: The increase in stroke volume during inotropic stimulation in patients with heart failure with reduced ejection fraction (HFrEF) is called the "pump function reserve." Few studies have reported on the relationship between pump function reserve and HF prognosis. In HFrEF patients who have pump function reserve, stroke volume increases during exercise. Simply put, the pulse pressure change (∆PP) during cardiopulmonary exercise testing (CPX) is closely related to the prognosis of patients with HFrEF. We hypothesized that ∆PP could predict disease severity and cardiovascular death in...
Source: Circulation Journal - July 29, 2020 Category: Cardiology Authors: Nakade T, Adachi H, Murata M, Naito S Tags: Circ J Source Type: research

Cancer Therapeutics-Related Cardiac Dysfunction  - Insights From Bench and Bedside of Onco-Cardiology.
Cancer Therapeutics-Related Cardiac Dysfunction - Insights From Bench and Bedside of Onco-Cardiology. Circ J. 2020 Jul 29;: Authors: Kadowaki H, Akazawa H, Ishida J, Komuro I Abstract Improvements in the long-term survival of cancer patients have led to growing awareness of the clinical importance of cancer therapeutics-related cardiac dysfunction (CTRCD), which can have a considerable effect on the prognosis and quality of life of cancer patients and survivors. Under such circumstances, onco-cardiology/cardio-oncology has emerged as a new discipline, with the aim of best managing cardiovascular com...
Source: Circulation Journal - July 29, 2020 Category: Cardiology Authors: Kadowaki H, Akazawa H, Ishida J, Komuro I Tags: Circ J Source Type: research

Earlier Diagnosis of Peripartum Cardiomyopathy (PPCM).
PMID: 32713882 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - July 23, 2020 Category: Cardiology Authors: Fett JD Tags: Circ J Source Type: research

Clinical Differences of Recent Myocardial Infarction Compared With Acute Myocardial Infarction  - Insights From the Tokyo CCU Network Multicenter Registry.
This study aimed to clarify characteristics, treatment strategy, and in-hospital outcomes of RMI patients in the Tokyo CCU network database.Methods and Results:In total, 1,853 RMI and 12,494 AMI patients from the Tokyo CCU network database during 2013-2016 were compared. Both RMI and AMI were redefined by onset times of 2-28 days and ≤24 h, respectively. The RMI group had a higher average age (70.4±12.9 vs. 68.0±13.4 years, P
Source: Circulation Journal - July 23, 2020 Category: Cardiology Authors: Ito R, Yamashita J, Chikamori T, Kondo S, Mitsuhashi Y, Iwata H, Saji M, Asano T, Wakabayashi K, Yahagi K, Shinke T, Mase T, Abe K, Miyachi H, Higuchi S, Kishi M, Tanaka H, Yamasaki M, Miyauchi K, Yamamoto T, Nagao K, Takayama M Tags: Circ J Source Type: research

Detailed Characterization of Vulnerable Plaque Morphology by High-Resolution Intravascular Ultrasound.
PMID: 32713884 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - July 23, 2020 Category: Cardiology Authors: Ando H, Ohashi H, Nakano Y, Takashima H, Amano T Tags: Circ J Source Type: research

Vasculopathy After Transradial Catheterization in a Scleroderma Patient.
PMID: 32713885 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - July 23, 2020 Category: Cardiology Authors: Shimada T, Habara S, Tanaka H, Kadota K Tags: Circ J Source Type: research

Missing P Wave on Electrocardiogram in Hypermagnesemia.
PMID: 32713886 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - July 23, 2020 Category: Cardiology Authors: Nishioka H Tags: Circ J Source Type: research

Pulsatile Strangulation of the Aorta  - A Rare Presentation and Etiology of Infective Endocarditis.
Pulsatile Strangulation of the Aorta - A Rare Presentation and Etiology of Infective Endocarditis. Circ J. 2020 Jul 23;: Authors: Chang WT, Chen ZC PMID: 32713887 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - July 23, 2020 Category: Cardiology Authors: Chang WT, Chen ZC Tags: Circ J Source Type: research

What Is the Optimal Dual Antiplatelet Therapy Strategy After Percutaneous Coronary Intervention in the Era of New-Generation Drug-Eluting Stent?
PMID: 32713888 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - July 23, 2020 Category: Cardiology Authors: Yokoyama H Tags: Circ J Source Type: research

Gastrointestinal Bleeding From Oral Anticoagulant Therapy Among Japanese Patients With Atrial Fibrillation Identified From the SAKURA Atrial Fibrillation Registry.
CONCLUSIONS: GI bleeding was strongly associated with anemia and renal impairment. Patients experiencing GI bleeding had higher risk for all-cause death than those without GI bleeding. PMID: 32713873 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - July 22, 2020 Category: Cardiology Authors: Murata N, Okumura Y, Nagashima K, Fukamachi D, Yokoyama K, Matsumoto N, Tachibana E, Kuronuma K, Oiwa K, Matsumoto M, Kojima T, Hanada S, Nomoto K, Arima K, Takahashi F, Kotani T, Ikeya Y, Fukushima S, Itou S, Kondo K, Chiku M, Ohno Y, Onikura M, Hirayama Tags: Circ J Source Type: research

Incidence of Cardiovascular Events and Safety Profile of Prasugrel in Korean Patients With Acute Coronary Syndrome.
CONCLUSIONS: The present results are similar to those observed in clinical trials where administration of low-dose aspirin plus prasugrel was associated with a low rate of major bleeding and CV events. PMID: 32713874 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - July 22, 2020 Category: Cardiology Authors: Chon MK, Jung SM, Lee SY, Lee SH, Hwang KW, Choi JH, Kim JS, Park YH, Kim JH, Chun KJ Tags: Circ J Source Type: research

Efficacy of Pulmonary Artery Pulsatility Index as a Measure of Right Ventricular Dysfunction in Stable Phase of Dilated Cardiomyopathy.
This study aimed to assess the ability of PAPi to stratify DCM patients without severe symptoms.Methods and Results:Between April 2000 and March 2018, a total of 162 DCM patients with stable symptoms were evaluated, including PAPi, and followed up for a median of 4.91 years. The mean age was 50.9±12.6 years and the mean LV ejection fraction (EF) was 30.5±8.3%. When divided into 2 groups based on median value of PAPi (low, L-PAPi [
Source: Circulation Journal - July 22, 2020 Category: Cardiology Authors: Kuwayama T, Morimoto R, Oishi H, Kato H, Kimura Y, Kazama S, Shibata N, Arao Y, Yamaguchi S, Hiraiwa H, Kondo T, Furusawa K, Okumura T, Murohara T Tags: Circ J Source Type: research

Clinical Characteristics and Outcomes of Heart Failure Patients With Long-Term Care Insurance  - Insights From the Kitakawachi Clinical Background and Outcome of Heart Failure Registry.
CONCLUSIONS: The level of LTCI was associated with a higher risk of the composite endpoint after discharge in acute HF patients. PMID: 32713877 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - July 21, 2020 Category: Cardiology Authors: Takabayashi K, Iwatsu K, Ikeda T, Morikami Y, Ichinohe T, Yamamoto T, Takenaka K, Takenaka H, Muranaka H, Fujita R, Okuda M, Nakajima O, Koito H, Terasaki Y, Kitamura T, Kitaguchi S, Nohara R Tags: Circ J Source Type: research

Comparison Between Clopidogrel and Prasugrel Associated With CYP2C19 Genotypes in Patients Receiving Percutaneous Coronary Intervention in a Japanese Population.
CONCLUSIONS: Among patients with theCYP2C19LOF allele, the use of clopidogrel was significantly associated with increased adverse events. Thus, further investigation is needed to establish the practical use ofCYP2C19genotyping. PMID: 32713878 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - July 21, 2020 Category: Cardiology Authors: Sawayama Y, Yamamoto T, Tomita Y, Asada K, Yagi N, Fukuyama M, Miyamoto A, Sakai H, Ozawa T, Isono T, Hira D, Terada T, Horie M, Nakagawa Y Tags: Circ J Source Type: research

Clopidogrel Monotherapy vs. Aspirin Monotherapy Following Short-Term Dual Antiplatelet Therapy in Patients Receiving Everolimus-Eluting Coronary Stent Implantation.
CONCLUSIONS: The effect of 1-month DAPT followed by clopidogrel monotherapy on clinical outcomes was similar to that of 3-month DAPT followed by aspirin monotherapy in patients receiving PCI. PMID: 32684537 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - July 18, 2020 Category: Cardiology Authors: Natsuaki M, Morimoto T, Watanabe H, Abe M, Kawai K, Nakao K, Ando K, Tanabe K, Ikari Y, Igarashi Hanaoka K, Morino Y, Kozuma K, Kadota K, Kimura T, STOPDAPT-1 and STOPDAPT-2 Trial Investigators Tags: Circ J Source Type: research

Overhanging Bioresorbable Vascular Scaffold Observed on Angioscopy 1 Year After Implantation.
PMID: 32684538 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - July 18, 2020 Category: Cardiology Authors: Inoue H, Okamura A, Iwamoto M, Sumiyoshi A, Tanaka K, Takayasu K, Kawamura K, Koyama Y, Inoue K, Iwakura K, Fujii K, Sakata Y, Nagai H Tags: Circ J Source Type: research

Independent Factors for In-Hospital Death Following Drug-Eluting Stent Thrombosis From the Japanese Adverse Event Report System.
CONCLUSIONS: LMT, CHF, hemodialysis, prior stroke, and older age were independently associated with higher risk of in-hospital death following DES-ST. If target patients have these factors, maximum preventive strategies against ST occurrence, including adequate dual-antiplatelet therapy duration and optimal DES deployment procedures, are required. PMID: 32684539 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - July 17, 2020 Category: Cardiology Authors: Mitsutake Y, Konishi A, Handa N, Ho M, Shirato H, Ito T, Koike K, Mochizuki S, Ishii K Tags: Circ J Source Type: research

Impact of the Temporal Relationship Between Atrial Fibrillation and Heart Failure on Prognosis After Ablation.
Abstract BACKGROUND: The purpose of this study was to elucidate the effect of the temporal relationship between atrial fibrillation (AF) and heart failure (HF) on clinical outcomes after catheter ablation.Methods and Results:We included 129 consecutive patients with AF and HF who underwent catheter ablation in hospital from December 2014 to September 2017. The patients were divided into 2 groups based on the temporal relationship between AF and HF. Group 1 consisted of 42 patients with AF following HF while Group 2 consisted of 87 patients with AF preceding HF or those who developed both of them simultaneously...
Source: Circulation Journal - July 17, 2020 Category: Cardiology Authors: Tsuji A, Masuda M, Asai M, Iida O, Okamoto S, Ishihara T, Nanto K, Kanda T, Tsujimura T, Matsuda Y, Okuno S, Hata Y, Mano T Tags: Circ J Source Type: research

Optimal Timing of Venoarterial-Extracorporeal Membrane Oxygenation in Acute Myocardial Infarction Patients Suffering From Refractory Cardiogenic Shock.
CONCLUSIONS: Early initiation of VA-ECMO before revascularization therapy might improve clinical outcomes in patients with AMI complicated by refractory CS. PMID: 32684541 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - July 17, 2020 Category: Cardiology Authors: Choi KH, Yang JH, Hong D, Park TK, Lee JM, Song YB, Hahn JY, Choi SH, Choi JH, Chung SR, Cho YH, Jeong DS, Sung K, Kim WS, Lee YT, Gwon HC Tags: Circ J Source Type: research

The Association of In-Hospital Transcatheter Aortic Valve Replacement Availability on Outcomes of Surgical Aortic Valve Replacement in Elderly Patients.
Abstract BACKGROUND: Transcatheter aortic valve replacement (TAVR) has been performed more and more frequently in elderly patients with aortic stenosis. We investigated the association of in-hospital availability of TAVR on outcomes of surgical aortic valve replacement (SAVR) in the era of TAVR.Methods and Results:We utilized data from the Japan Adult Cardiovascular Surgery Database. Between October 2013 and December 2016, 9,330 patients aged ≥80 years underwent isolated SAVR or SAVR with coronary artery bypass grafting in 557 centers in Japan. We assessed the associations of in-hospital TAVR availability w...
Source: Circulation Journal - July 16, 2020 Category: Cardiology Authors: Tabata M, Kumamaru H, Ono A, Miyata H, Sato Y, Motomura N Tags: Circ J Source Type: research

Doppler-Derived Intrarenal Venous Flow Mirrors Right-Sided Heart Hemodynamics in Patients With Cardiovascular Disease.
CONCLUSIONS: IRVF interruption was closely related to RAP elevation at each specific point of the cardiac cycle rather than to mean RAP levels, suggesting that the characteristics of IRVF mirror right-sided heart hemodynamics, not mean RAP. PMID: 32669529 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - July 16, 2020 Category: Cardiology Authors: Seo Y, Iida N, Yamamoto M, Ishizu T, Ieda M, Ohte N Tags: Circ J Source Type: research

Prevalence of the Academic Research Consortium for High Bleeding Risk Criteria and Prognostic Value of a Simplified Definition.
Abstract BACKGROUND: The Academic Research Consortium for High Bleeding Risk (ARC-HBR) criteria have been suggested as the standard definition of HBR. However, the prevalence of individual criteria and their prognostic value for long-term bleeding events after percutaneous coronary intervention are scarcely studied.Methods and Results:The study population comprised 1,193 patients treated with everolimus-eluting stents between 2010 and 2011. Data on all 17 major and minor criteria of the ARC-HBR definition were retrospectively collected, and applied to this study population. Major bleeding was defined as the oc...
Source: Circulation Journal - July 16, 2020 Category: Cardiology Authors: Miura K, Shimada T, Ohya M, Murai R, Amano H, Kubo S, Tada T, Tanaka H, Fuku Y, Goto T, Kadota K Tags: Circ J Source Type: research

Hypertrophic Cardiomyopathy  - A Heterogeneous and Lifelong Disease in the Real World.
Hypertrophic Cardiomyopathy - A Heterogeneous and Lifelong Disease in the Real World. Circ J. 2020 Jul 14;: Authors: Kitaoka H, Kubo T, Doi YL Abstract Hypertrophic cardiomyopathy (HCM) is the most frequent hereditary cardiomyopathy, showing an autosomal-dominant f inheritance. A great deal of attention has been paid to genetics, left ventricular tract obstruction and the prediction and prevention of sudden cardiac death in HCM. Needless to say, these are very important, but we should recognize the heterogeneity in etiology, morphology, clinical course and management of this unique cardiomyopathy. A...
Source: Circulation Journal - July 14, 2020 Category: Cardiology Authors: Kitaoka H, Kubo T, Doi YL Tags: Circ J Source Type: research

Risk of Pulmonary Arterial Hypertension During Qing-Dai Use for the Treatment of Ulcerative Colitis.
PMID: 32655110 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - July 11, 2020 Category: Cardiology Authors: Adachi S, Nakano Y, Kondo T Tags: Circ J Source Type: research

2-Year Outcomes of Left Atrial Appendage Occlusion With WATCHMAN in Japanese Atrial Fibrillation Patients.
PMID: 32655111 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - July 11, 2020 Category: Cardiology Authors: Harada M Tags: Circ J Source Type: research

Novel Players and a Target of Stem Cell Therapy for the Heart.
PMID: 32655112 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - July 11, 2020 Category: Cardiology Authors: Inoue O, Yamaguchi K, Takamura M Tags: Circ J Source Type: research

Direct Oral Anticoagulants for the Treatment of Cancer-Associated Venous Thromboembolism in Real-World Clinical Practice  - Caution Regarding Substantial Frequency of Bleeding Complications.
Direct Oral Anticoagulants for the Treatment of Cancer-Associated Venous Thromboembolism in Real-World Clinical Practice - Caution Regarding Substantial Frequency of Bleeding Complications. Circ J. 2020 Jul 11;: Authors: Hosoi Y PMID: 32655113 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - July 11, 2020 Category: Cardiology Authors: Hosoi Y Tags: Circ J Source Type: research

Japanese Heart Failure Society 2018 Scientific Statement on Nutritional Assessment and Management in Heart Failure Patients.
Society, Expert Consensus Writing Committee PMID: 32655089 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - July 10, 2020 Category: Cardiology Authors: Yamamoto K, Tsuchihashi-Makaya M, Kinugasa Y, Iida Y, Kamiya K, Kihara Y, Kono Y, Sato Y, Suzuki N, Takeuchi H, Higo T, Miyazawa Y, Miyajima I, Yamashina A, Yoshita K, Washida K, Kuzuya M, Takahashi T, Nakaya Y, Hasebe N, Tsutsui H, Japanese Heart Failure Tags: Circ J Source Type: research

JCS/JSCS 2020 Guideline on Diagnosis and Management of Cardiovascular Sequelae in Kawasaki Disease.
T, Japanese Circulation Society Joint Working Group PMID: 32641591 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - July 8, 2020 Category: Cardiology Authors: Fukazawa R, Kobayashi J, Ayusawa M, Hamada H, Miura M, Mitani Y, Tsuda E, Nakajima H, Matsuura H, Ikeda K, Nishigaki K, Suzuki H, Takahashi K, Suda K, Kamiyama H, Onouchi Y, Kobayashi T, Yokoi H, Sakamoto K, Ochi M, Kitamura S, Hamaoka K, Senzaki H, Kimur Tags: Circ J Source Type: research

Heart Failure in Atrial Fibrillation  - An Update on Clinical and Echocardiographic Implications.
Heart Failure in Atrial Fibrillation - An Update on Clinical and Echocardiographic Implications. Circ J. 2020 Jul 08;: Authors: Taniguchi N, Miyasaka Y, Suwa Y, Harada S, Nakai E, Shiojima I Abstract Atrial fibrillation (AF) is the most common sustained arrhythmia in adults and has unfavorable consequences such as stroke, heart failure (HF), and death. HF is the most common adverse event following AF and the leading cause of death. Therefore, identifying the association between AF and HF is important to establish risk stratification for HF in AF. Recent studies suggested that left atrial and ventric...
Source: Circulation Journal - July 8, 2020 Category: Cardiology Authors: Taniguchi N, Miyasaka Y, Suwa Y, Harada S, Nakai E, Shiojima I Tags: Circ J Source Type: research

Direct Oral Anticoagulant Therapy for Cancer-Associated Venous Thromboembolism in Routine Clinical Practice.
CONCLUSIONS: In DOAC therapy for cancer-associated VTE, major bleeding prevention is important because it is an independent risk factor of death. PMID: 32624519 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - July 4, 2020 Category: Cardiology Authors: Ogino Y, Ishigami T, Minamimoto Y, Kimura Y, Akiyama E, Okada K, Matsuzawa Y, Maejima N, Iwahashi N, Hibi K, Kosuge M, Ebina T, Ishikawa T, Tamura K, Kimura K Tags: Circ J Source Type: research

Prognosis and Clinical Characteristics of Dilated Cardiomyopathy With Family History via Pedigree Analysis.
Abstract BACKGROUND: The clinical characteristics and prognostic outcomes of dilated cardiomyopathy (DCM) with a familial history (FHx) via pedigree analysis are unclear.Methods and Results:We conducted a prospective observational study of 514 consecutive Japanese patients with DCM. FHx was defined as the presence of DCM in ≥1 family member within 2-degrees relative based on pedigree analysis. The primary endpoint was a composite of major cardiac events (sudden cardiac death and pump failure death). The prevalence of FHx was 7.4% (n=38). During a median follow-up of 3.6 years, 77 (15%) patients experienced ...
Source: Circulation Journal - July 3, 2020 Category: Cardiology Authors: Marume K, Noguchi T, Tateishi E, Morita Y, Miura H, Nishimura K, Ohta-Ogo K, Yamada N, Tsujita K, Izumi C, Kusano K, Ogawa H, Yasuda S Tags: Circ J Source Type: research

Tribute to Dr. Tomisaku Kawasaki  - Discoverer of Kawasaki Disease and a Great Pediatrician.
Tribute to Dr. Tomisaku Kawasaki - Discoverer of Kawasaki Disease and a Great Pediatrician. Circ J. 2020 Jul 02;: Authors: Kato H PMID: 32611935 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - July 2, 2020 Category: Cardiology Authors: Kato H Tags: Circ J Source Type: research

Surgical Aortic Valve Replacement for Aortic Stenosis in Dialysis Patients  - Analysis of Japan Cardiovascular Surgery Database.
CONCLUSIONS: Compared with non-dialysis patients, SAVR in dialysis patients was associated with high rates of mortality and morbidity. An appropriate surgical strategy and careful perioperative assessment and management for prevention of infection, and respiratory and gastrointestinal complications might contribute to improved clinical outcomes after SAVR in these patients. PMID: 32612017 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - July 1, 2020 Category: Cardiology Authors: Yamauchi T, Yamamoto H, Miyata H, Kobayashi J, Masai T, Motomura N Tags: Circ J Source Type: research

Impact of Renal Dysfunction on Left Atrial Structural Remodeling and Recurrence After Catheter Ablation for Atrial Fibrillation  - A Propensity Score Matching Analysis.
This study aimed to determine whether renal dysfunction had an independent effect on the presence of LVZs and recurrence after AF ablation, using propensity score (PS) matching analysis.Methods and Results:448 consecutive patients who underwent their initial AF ablation were enrolled. Chronic kidney disease (CKD) was defined as an estimated glomerular filtration rate (eGFR)
Source: Circulation Journal - July 1, 2020 Category: Cardiology Authors: Takahashi Y, Yamaguchi T, Fukui A, Otsubo T, Hirota K, Kawano Y, Nakashima K, Tahara M, Kitai T, Kawaguchi A, Takahashi N, Node K Tags: Circ J Source Type: research

(Retraction Request) Electrophysiological Characteristics and Radiofrequency Catheter Ablation Treatment of Idiopathic Ventricular Arrhythmias Successfully Ablated From the Ostium of the Coronary Sinus.
PMID: 32581196 [PubMed - in process] (Source: Circulation Journal)
Source: Circulation Journal - June 27, 2020 Category: Cardiology Authors: Yui Y Tags: Circ J Source Type: research

(Retraction Request) Efficacy of Intensive Radiofrequency Energy Delivery to the Localized Dense Scar Area in Post-Infarction Ventricular Tachycardia Ablation  - A Comparative Study With Standard Strategy Targeting the Infarcted Border Zone.
(Retraction Request) Efficacy of Intensive Radiofrequency Energy Delivery to the Localized Dense Scar Area in Post-Infarction Ventricular Tachycardia Ablation - A Comparative Study With Standard Strategy Targeting the Infarcted Border Zone. Circ J. 2020;84(7):1198 Authors: Kuroki K PMID: 32581197 [PubMed - in process] (Source: Circulation Journal)
Source: Circulation Journal - June 27, 2020 Category: Cardiology Authors: Kuroki K Tags: Circ J Source Type: research

CORRIGENDUM: Acute Coronary Syndrome With Unprotected Left Main Coronary Artery Culprit  - An Observation From the AOI-LMCA Registry.
CORRIGENDUM: Acute Coronary Syndrome With Unprotected Left Main Coronary Artery Culprit - An Observation From the AOI-LMCA Registry. Circ J. 2020;84(7):1199-1206 Authors: Higami H, Toyofuku M, Morimoto T, Ohya M, Fuku Y, Yamaji K, Muranishi H, Yamaji Y, Nishida K, Furukawa D, Tada T, Ko E, Ando K, Sakamoto H, Tamura T, Kawai K, Kadota K, Kimura T, AOI-LMCA Stenting Registry Investigators PMID: 32581198 [PubMed - in process] (Source: Circulation Journal)
Source: Circulation Journal - June 27, 2020 Category: Cardiology Authors: Higami H, Toyofuku M, Morimoto T, Ohya M, Fuku Y, Yamaji K, Muranishi H, Yamaji Y, Nishida K, Furukawa D, Tada T, Ko E, Ando K, Sakamoto H, Tamura T, Kawai K, Kadota K, Kimura T, AOI-LMCA Stenting Registry Investigators Tags: Circ J Source Type: research

CORRIGENDUM: Association of Albuminuria With White Matter Hyperintensities Volume on Brain Magnetic Resonance Imaging in Elderly Japanese  - The Hisayama Study.
CORRIGENDUM: Association of Albuminuria With White Matter Hyperintensities Volume on Brain Magnetic Resonance Imaging in Elderly Japanese - The Hisayama Study. Circ J. 2020;84(7):1207 Authors: Yamasaki K, Hata J, Furuta Y, Hirabayashi N, Ohara T, Yoshida D, Hirakawa Y, Nakano T, Kitazono T, Ninomiya T PMID: 32581199 [PubMed - in process] (Source: Circulation Journal)
Source: Circulation Journal - June 27, 2020 Category: Cardiology Authors: Yamasaki K, Hata J, Furuta Y, Hirabayashi N, Ohara T, Yoshida D, Hirakawa Y, Nakano T, Kitazono T, Ninomiya T Tags: Circ J Source Type: research

Bone Marrow Mesenchymal Stem Cell-Derived Exosomal miRNA-29c Decreases Cardiac Ischemia/Reperfusion Injury Through Inhibition of Excessive Autophagy via the PTEN/Akt/mTOR Signaling Pathway.
CONCLUSIONS: This study highlighted the role of miR-29c in regulating autophagy under cardiac I/R injury, which also extended existing mechanisms of a stem cell and its derivative to explore potential therapeutic interventions in ischemic heart diseases. PMID: 32581152 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - June 25, 2020 Category: Cardiology Authors: Li T, Gu J, Yang O, Wang J, Wang Y, Kong J Tags: Circ J Source Type: research

Differences in Intravascular Ultrasound Measurement Values Between Treatment Modalities for Restenosis in Femoropopliteal Lesions.
CONCLUSIONS: The factors related to patency differed depending on the treating modality. The findings suggest that IVUS is a useful tool for predicting patency because it can provide a more accurate evaluation after EVT for femoropopliteal lesions. PMID: 32581151 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - June 24, 2020 Category: Cardiology Authors: Aihara H, Higashitani M, Takimura H, Tobita K, Jujo K, Hozawa K, Yamaguchi T, Iwata Y, Tokuyama H, Sakurai M, Murata N, Fujimoto Y, Kikuchi A, Koganei H, Sato A, Noguchi Y, Ieda M Tags: Circ J Source Type: research

Slowly Developed Coronary Artery Aneurysms in a Patient With Probable Kawasaki Disease.
PMID: 32554944 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - June 18, 2020 Category: Cardiology Authors: Mizutani Y, Ishikawa T, Watanabe S, Kobayashi S, Taguchi I Tags: Circ J Source Type: research

Atrial Septal Hematoma After Transcatheter Aortic Valve Implantation.
PMID: 32554945 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - June 18, 2020 Category: Cardiology Authors: Tanabe S, Nakano Y, Ando H, Ohashi H, Mukai K, Amano T Tags: Circ J Source Type: research

Magnesium Deficiency Causes Transcriptional Downregulation of Kir2.1 and Kv4.2 Channels in Cardiomyocytes Resulting in QT Interval Prolongation.
CONCLUSIONS: Intracellular Mg deficiency downregulates IK1and Itoin cardiomyocytes, and this is mediated by the transcription factors, NFAT and CREB. These results provide a novel mechanism for the long-term QT interval prolongation in hypomagnesemia. PMID: 32554946 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - June 18, 2020 Category: Cardiology Authors: Shimaoka T, Wang Y, Morishima M, Miyamoto S, Ono K Tags: Circ J Source Type: research

Long-Term Outcomes of the Mosaic Aortic Porcine Bioprosthesis in Japan  - Results From the Japan Mosaic Valve Long-Term Multicenter Study.
This study retrospectively evaluated the long-term patient outcomes and durability of the Mosaic aortic porcine bioprosthesis in the Japan Mosaic valve long-term multicenter study.Methods and Results:We reviewed the records of 1,202 patients who underwent aortic valve replacement with the Mosaic bioprosthesis at 10 centers in Japan (1999-2014). Patient data were collected using Research Electronic Data Capture. Patient survival was determined by Kaplan-Meier methodology. Freedom from structural valve deterioration (SVD) and valve-related reoperation and death were determined by actuarial methods. The median (interquart...
Source: Circulation Journal - June 16, 2020 Category: Cardiology Authors: Yoshikawa Y, Okada Y, Okita Y, Yaku H, Kobayashi J, Uesugi H, Takanashi S, Ito T, Nakao T, Koyama T, Sakaguchi T, Yamamoto K, Sawa Y Tags: Circ J Source Type: research

Preoperative Threshold for Normalizing Right Ventricular Volume After Transcatheter Closure of Adult Atrial Septal Defect.
Abstract BACKGROUND: The latest guidelines recommend early intervention in adult atrial septal defect (ASD) patients with signs of right ventricular (RV) enlargement. However, the criteria of RV enlargement for optimal intervention remain unclear. We investigated the preoperative determinants for normalizing the RV volume after transcatheter closure of ASD in adults.Methods and Results:We retrospectively analyzed 52 ASD patients who underwent transcatheter closure. Cardiac magnetic resonance imaging (CMR) measured RV volume before and 1 year after the closure. The patients were divided into normalized (postope...
Source: Circulation Journal - June 16, 2020 Category: Cardiology Authors: Umemoto S, Sakamoto I, Abe K, Ishikita A, Yamasaki Y, Hiasa KI, Ide T, Tsutsui H Tags: Circ J Source Type: research

Impact of Cardiovascular Disease on Clinical Characteristics and Outcomes of Coronavirus Disease 2019 (COVID-19).
Abstract BACKGROUND: To investigate the effect of cardiovascular disease (CVD) on the global pandemic, coronavirus disease 2019 (COVID-19), we analyzed the cases of laboratory-confirmed COVID-19 patients in Wuhan.Methods and Results:Data were extracted from the medical records. SARS-CoV-2 RNA was confirmed by RT-PCR. A total of 33 (53.2%) of 62 cases with CVD, who had higher prevalence of severe COVID-19 compared with non-CVD patients (P=0.027). The median age of all patients was 66.0 (53.3, 73.0) years old. Coronary artery disease (11.3%) and hypertension (38.7%) were the common coexisting CVDs in COVID-19 pa...
Source: Circulation Journal - June 13, 2020 Category: Cardiology Authors: Xie Y, You Q, Wu C, Cao S, Qu G, Yan X, Han X, Wang C, Zhang H Tags: Circ J Source Type: research

Prognostic Impact of No-Flow Time on 30-Day Neurological Outcomes in Patients With Out-of-Hospital Cardiac Arrest Who Received Extracorporeal Cardiopulmonary Resuscitation.
This study examined the impact of the time interval from collapse to start of CPR (no-flow time, NF time) and the time interval from start of CPR to implementation of extracorporeal CPR (ECPR) (low-flow time, LF time) on neurological outcomes.Methods and Results:During the period from 2010 to 2015, we enrolled 85 patients who received ECPR. Fourteen patients (16.5%) showed favorable 30-day neurological recovery. NF time was shorter in the favorable neurological recovery group than in the unfavorable recovery group (1.4±3.0 vs. 5.2±5.8 min, P
Source: Circulation Journal - June 11, 2020 Category: Cardiology Authors: Murakami N, Kokubu N, Nagano N, Nishida J, Nishikawa R, Nakata J, Suzuki Y, Tsuchihashi K, Narimatsu E, Miura T Tags: Circ J Source Type: research

NT5E Genetic Mutation Is a Rare But Important Cause of Intermittent Claudication and Chronic Limb-Threatening Ischemia.
CONCLUSIONS: Vascular specialists need to recognize CALJA as a rare cause of ischemic IC and CLTI. PMID: 32522903 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - June 11, 2020 Category: Cardiology Authors: Azuma N, Uchida T, Kikuchi S, Sadahiro M, Shintani T, Yanagi K, Higashita R, Yamashita A, Makita Y, Kaname T Tags: Circ J Source Type: research

Safety and Efficacy of Human Muse Cell-Based Product for Acute Myocardial Infarction in a First-in-Human Trial.
CONCLUSIONS: The first-in-human intravenous administration of CL2020 was safe and markedly improved LV function in STEMI patients. PMID: 32522904 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - June 11, 2020 Category: Cardiology Authors: Noda T, Nishigaki K, Minatoguchi S Tags: Circ J Source Type: research