Uremic Toxin-Targeting as a Therapeutic Strategy for Preventing Cardiorenal Syndrome.
Abstract Chronic kidney disease (CKD) is a global health problem. CKD patients are at high risk of developing cardiovascular disease (CVD), including coronary artery disease, heart failure and stroke. Several factors invoke a vicious cycle of CKD and CVD, which is referred as to "cardiorenal syndrome". Among these factors, the compounds retained through loss of renal excretion play a pathological role in causing atherosclerosis and CVD. These compounds have been broadly classified as uremic toxins because of their accumulation with declining renal function and cytotoxicity. The major uremic toxins contri...
Source: Circulation Journal - December 11, 2019 Category: Cardiology Authors: Taguchi K, Elias BC, Brooks CR, Ueda S, Fukami K Tags: Circ J Source Type: research

Coronary Artery Perforation and Tamponade  - Incidence, Risk Factors, Predictors and Outcomes From 12 Years' Data of the SCAAR Registry.
Coronary Artery Perforation and Tamponade - Incidence, Risk Factors, Predictors and Outcomes From 12 Years' Data of the SCAAR Registry. Circ J. 2019 Dec 07;: Authors: Harnek J, James S, Lagerqvist B Abstract BACKGROUND: The incidence and short- and long-term outcomes of coronary artery perforation (CAP) are not well described.Methods and Results:We analyzed the characteristics and the short- and long-term outcomes of CAP among 243,149 patients undergoing percutaneous coronary interventions (PCI) from 2005 until 2017 in the national Swedish registry. We identified 1,008 cases of CAP with an incid...
Source: Circulation Journal - December 7, 2019 Category: Cardiology Authors: Harnek J, James S, Lagerqvist B Tags: Circ J Source Type: research

Open-Label Two-Dose Pilot Study of Landiolol for the Treatment of Atrial Fibrillation/Atrial Flutter in Caucasian Patients.
mpl G Abstract BACKGROUND: We investigated for the first time the suitability of landiolol, an ultra-short-acting β1-specific β-blocker, for the treatment of atrial fibrillation/atrial flutter (AF/AFL) in Caucasian patients.Methods and Results:The 20 study patients received landiolol as a continuous infusion (starting dose 40 µg/kg/min) with (B+CI) or without (CI) a preceding bolus dose (100 µg/kg/min administered over 1 min) in a prospective open-label study. The primary endpoint was the proportion of patients with sustained heart rate (HR) reduction ≥20% or to
Source: Circulation Journal - December 6, 2019 Category: Cardiology Authors: Stix G, Wolzt M, Domanovits H, Kadlecová P, Husch B, Trebs M, Hodisch J, Unger M, Krumpl G Tags: Circ J Source Type: research

Advantages and Emerging Problems of Novel Treatments for Transthyretin Cardiac Amyloidosis.
PMID: 31813898 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - December 6, 2019 Category: Cardiology Authors: Okumura T, Murohara T Tags: Circ J Source Type: research

Benefits of the Modified Bicaval Anastomosis Technique for Orthotopic Heart Transplantation From a Size-Mismatched Marginal Donor.
CONCLUSIONS: The mBCAT prevented caval anastomosis-related complications in size-mismatched HTx and achieved excellent hemodynamics regardless of donor size. PMID: 31801926 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - December 5, 2019 Category: Cardiology Authors: Kakuta T, Fukushima S, Shimahara Y, Yajima S, Kawamoto N, Tadokoro N, Fukushima N, Kitamura S, Kobayashi J, Fujita T Tags: Circ J Source Type: research

Risk of Out-of-Hospital Cardiac Arrest in Aged Individuals in Relation to Cold Ambient Temperature  - A Report From North Tochigi Experience.
Risk of Out-of-Hospital Cardiac Arrest in Aged Individuals in Relation to Cold Ambient Temperature - A Report From North Tochigi Experience. Circ J. 2019 Dec 05;: Authors: Yoshinaga T, Shiba N, Kunitomo R, Hasegawa N, Suzuki M, Sekiguchi C, Shinozawa Y, Tsuge S, Kitajima T, Miyahara Y, Misawa Y Abstract BACKGROUND: The impact of cold ambient temperature on out-of-hospital cardiac arrest (OHCA) in aged individuals caused by cardiovascular events in indoor environments has not been investigated sufficiently.Methods and Results:We conducted a case-crossover study. The relationship between OHCA caus...
Source: Circulation Journal - December 5, 2019 Category: Cardiology Authors: Yoshinaga T, Shiba N, Kunitomo R, Hasegawa N, Suzuki M, Sekiguchi C, Shinozawa Y, Tsuge S, Kitajima T, Miyahara Y, Misawa Y Tags: Circ J Source Type: research

Left Ventricular Inflow Velocity Pattern in Patients With Symptomatic Premature Ventricular Contraction.
Abstract BACKGROUND: Because premature ventricular contractions (PVCs) are one of the most common arrhythmias, but with unclear causative mechanisms, we studied the hemodynamic features that can cause symptomatic PVCs.Methods and Results:We studied 109 patients (48 males, age 60±19 years) with frequent monomorphic PVCs and no structural heart disease. The left ventricular inflow diastolic filling velocity was recorded by transthoracic echocardiography (TTE) at the time of PVCs in all patients. We assessed the PVC E wave flow (E wave velocity×duration at PVC). A total of 38 patients (35%) had PVC-r...
Source: Circulation Journal - December 4, 2019 Category: Cardiology Authors: Takahashi S, Mine T, Ashida K, Kishima H, Masuyama T, Ishihara M Tags: Circ J Source Type: research

Can a New Algorithm of Cardiac Resynchronization Therapy (Adaptive CRT) Expand Its Utility?
PMID: 31801921 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - December 4, 2019 Category: Cardiology Authors: Kurita T Tags: Circ J Source Type: research

Differences in Flow-Gradient Patterns Between Severe Bicuspid Aortic Stenosis and Severe Tricuspid Aortic Stenosis  - Mechanistic Insight From Multimodal Imaging.
Differences in Flow-Gradient Patterns Between Severe Bicuspid Aortic Stenosis and Severe Tricuspid Aortic Stenosis - Mechanistic Insight From Multimodal Imaging. Circ J. 2019 Nov 30;: Authors: Kim D, Shim CY, Kim YJ, Nam K, Hong GR, Lee SH, Lee S, Ha JW Abstract BACKGROUND: We investigated the flow-gradient pattern characteristics and associated factors in severe bicuspid aortic stenosis (AS) compared with severe tricuspid AS.Methods and Results:A total of 252 patients with severe AS (115 bicuspid vs. 137 tricuspid) who underwent aortic valve (AV) replacement were retrospectively analyzed. Patie...
Source: Circulation Journal - November 30, 2019 Category: Cardiology Authors: Kim D, Shim CY, Kim YJ, Nam K, Hong GR, Lee SH, Lee S, Ha JW Tags: Circ J Source Type: research

Influence of Preadmission Frailty on Short- and Mid-Term Prognoses in Octogenarians With ST-Elevation Myocardial Infarction.
Abstract BACKGROUND: Octogenarians, who are frequently frail, represent a large proportion of patients admitted for ST-segment elevation myocardial infarction (STEMI). We investigated the relationship between frailty, assessed by the Canadian Study of Health and Aging Clinical Frailty Scale (CFS), and short- and mid-term prognoses in octogenarian STEMI patients.Methods and Results:We used a multicenter registry data of 1,301 patients with STEMI undergoing percutaneous coronary intervention (PCI) between January 2014 and December 2016. Of them, 273 were retrospectively analyzed after categorization into 3 group...
Source: Circulation Journal - November 29, 2019 Category: Cardiology Authors: Yoshioka N, Takagi K, Morishima I, Morita Y, Uemura Y, Inoue Y, Umemoto N, Shibata N, Negishi Y, Yoshida R, Tanaka A, Ishii H, Murohara T, N-Registry Investigators Tags: Circ J Source Type: research

Relationship Between Respiratory Compensation Point and Anaerobic Threshold in Patients With Heart Failure With Reduced Ejection Fraction.
Abstract BACKGROUND: Cardiopulmonary exercise testing (CPX) is used in the prognostic evaluation of patients with heart failure with reduced ejection fraction (HFrEF). In these patients, the ventilation feedback system is dysfunctional, and overactive peripheral chemoreceptors may be responsible for the early appearance of the respiratory compensation point (RCP) after the anaerobic threshold (AT). The mechanism of RCP appearance remains unknown and very few studies have reported the relationship between RCP and heart failure. We hypothesized that the duration between the RCP and AT (RCP-AT time) can predict the s...
Source: Circulation Journal - November 28, 2019 Category: Cardiology Authors: Nakade T, Adachi H, Murata M, Naito S Tags: Circ J Source Type: research

Effects of Angiotensin-Converting Enzyme Inhibitors and Angiotensin-Receptor Blockers in Heart Failure With Chronic Kidney Disease  - Propensity Score Matching Analysis.
CONCLUSIONS: Prescription of an ACEI or ARB at discharge was associated with reduction in all-cause mortality in patients with acute HF and CKD. Clinicians need to be aware of the prognostic value and consider prescribing ACEI or ARB to high-risk patients. PMID: 31776309 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - November 28, 2019 Category: Cardiology Authors: Kim HJ, Lee MH, Jo SH, Seo WW, Kim SE, Kim KJ, Choi JO, Ahn HS, Choi DJ, Ryu KH Tags: Circ J Source Type: research

Incidence and Distribution of Cerebral Embolism After Cardiac Surgery According to the Systemic Perfusion Strategy  - A Diffusion-Weighted Magnetic Resonance Imaging Study.
CONCLUSIONS: According to the results of postoperative DW-MRI, retrograde perfusion itself might not increase the incidence of postoperative cerebral embolism in properly selected cardiac surgery patients undergoing routine preoperative CTA examination. PMID: 31776305 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - November 26, 2019 Category: Cardiology Authors: Je HG, Ju MH, Lee CH, Lim MH, Lee JH, Oh HR Tags: Circ J Source Type: research

Prasugrel for Japanese Patients With Ischemic Heart Disease in Long-Term Clinical Practice (PRASFIT-Practice II)  - 1-Year Follow-up Results of a Postmarketing Observational Study.
CONCLUSIONS: The 1-year follow-up results showed long-term effectiveness and safety of prasugrel at dosages approved in Japan for the treatment of IHD patients undergoing PCI. PMID: 31748446 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - November 21, 2019 Category: Cardiology Authors: Nakamura M, Kitazono T, Kozuma K, Sekine T, Nakamura S, Shiosakai K, Iizuka T Tags: Circ J Source Type: research

Extremely Rare Case of Submitral Aneurysm With Left Atrium Communication in a Japanese Patient.
PMID: 31748447 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - November 21, 2019 Category: Cardiology Authors: Matsuhiro Y, Shutta R, Yanagawa K, Nakamura H, Yasumoto K, Tsuda M, Tanaka A, Okamoto N, Matsunaga-Lee Y, Yano M, Yamato M, Egami Y, Nishino M, Tanouchi J Tags: Circ J Source Type: research

Keloid as an Underrecognized Potential Risk Factor for Post-Procedural Pulmonary Vein Stenosis.
PMID: 31748435 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - November 19, 2019 Category: Cardiology Authors: Yamasaki H, Hoshi T, Aonuma K, Nogami A, Ieda M Tags: Circ J Source Type: research

Acute Popliteal Artery Thrombosis After Arthroscopic Anterior Cruciate Ligament Reconstruction.
PMID: 31748436 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - November 19, 2019 Category: Cardiology Authors: Otowa K, Maruhashi Y, Chikata A, Maruyama M, Usuda K Tags: Circ J Source Type: research

A Statement on the Appropriate Administration of Tafamidis in Patients With Transthyretin Cardiac Amyloidosis.
Abstract Transthyretin cardiac amyloidosis is a progressive and life-threating disease that is significantly underdiagnosed, and the actual number of patients with the disease is presently unknown. Accumulation of wild-type transthyretin-derived amyloid in the heart is a common finding in very elderly patients. Recent clinical trials demonstrated that tafamidis reduced all-cause death and the number of cardiovascular hospitalizations when compared with placebo. The Japanese Ministry of Health, Labour and Welfare approved tafamidis (Vyndaqel®, Pfizer Inc.) for the treatment of cardiomyopathy caused by both wild...
Source: Circulation Journal - November 16, 2019 Category: Cardiology Authors: Endo J, Sano M, Izumiya Y, Tsujita K, Nakamura K, Tahara N, Kuwahara K, Inomata T, Ueda M, Sekijima Y, Ando Y, Tsutsui H, Isobe M, Fukuda K Tags: Circ J Source Type: research

Optical Technology Stepping Forward  - Utility of Intracoronary Optical Coherence Tomography.
Optical Technology Stepping Forward - Utility of Intracoronary Optical Coherence Tomography. Circ J. 2019 Nov 16;: Authors: Yamamoto MH, Shinke T PMID: 31735732 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - November 16, 2019 Category: Cardiology Authors: Yamamoto MH, Shinke T Tags: Circ J Source Type: research

Efficacy and Reproducibility of Attenuation-Compensated Optical Coherence Tomography for Assessing External Elastic Membrane Border and Plaque Composition in Native and Stented Segments  - An In Vivo and Histology-Based Study.
Efficacy and Reproducibility of Attenuation-Compensated Optical Coherence Tomography for Assessing External Elastic Membrane Border and Plaque Composition in Native and Stented Segments - An In Vivo and Histology-Based Study. Circ J. 2019 Nov 15;: Authors: Ramasamy A, Ng J, White S, Johnson TW, Foin N, Girard MJA, Dijkstra J, Amersey R, Scoltock S, Koganti S, Jones D, Jin C, Räber L, Serruys PW, Torii R, Crake T, Rakhit R, Baumbach A, Mathur A, Bourantas CV Abstract BACKGROUND: Attenuation-compensated (AC) technique was recently introduced to improve the plaque characterization of optical coher...
Source: Circulation Journal - November 15, 2019 Category: Cardiology Authors: Ramasamy A, Ng J, White S, Johnson TW, Foin N, Girard MJA, Dijkstra J, Amersey R, Scoltock S, Koganti S, Jones D, Jin C, Räber L, Serruys PW, Torii R, Crake T, Rakhit R, Baumbach A, Mathur A, Bourantas CV Tags: Circ J Source Type: research

Function Follows Form  - A Review of Cardiac Cell Therapy.
Function Follows Form - A Review of Cardiac Cell Therapy. Circ J. 2019 Nov 13;: Authors: Nakamura K, Murry CE Abstract The investment of nearly 2 decades of clinical investigation into cardiac cell therapy has yet to change cardiovascular practice. Recent insights into the mechanism of cardiac regeneration help explain these results and provide important context in which we can develop next-generation therapies. Non-contractile cells such as bone marrow or adult heart derivatives neither engraft long-term nor induce new muscle formation. Correspondingly, these cells offer little functional benefit t...
Source: Circulation Journal - November 13, 2019 Category: Cardiology Authors: Nakamura K, Murry CE Tags: Circ J Source Type: research

Guideline on the Use of Iodinated Contrast Media in Patients With Kidney Disease 2018.
Y, Miyauchi T, Ito Y, Miyazawa R, Kanno Y, Ogawa T, Hayashi H, Koshi E, Kosugi T, Yasuda Y, Japanese Society of Nephrology, Japan Radiological Society, Japanese Circulation Society Joint Working Group PMID: 31708511 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - November 11, 2019 Category: Cardiology Authors: Isaka Y, Hayashi H, Aonuma K, Horio M, Terada Y, Doi K, Fujigaki Y, Yasuda H, Sato T, Fujikura T, Kuwatsuru R, Toei H, Murakami R, Saito Y, Hirayama A, Murohara T, Sato A, Ishii H, Takayama T, Watanabe M, Awai K, Oda S, Murakami T, Yagyu Y, Joki N, Komats Tags: Circ J Source Type: research

Standard Cardiac Rehabilitation Program for Heart Failure.
se Association of Cardiac Rehabilitation Standard Cardiac Rehabilitation Program Planning Committee PMID: 31708554 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - November 9, 2019 Category: Cardiology Authors: Izawa H, Yoshida T, Ikegame T, Izawa KP, Ito Y, Okamura H, Osada N, Kinugawa S, Kubozono T, Kono Y, Kobayashi K, Nishigaki K, Higo T, Hirashiki A, Miyazawa Y, Morio Y, Yanase M, Yamada S, Ikeda H, Momomura SI, Kihara Y, Yamamoto K, Goto Y, Makita S, Japan Tags: Circ J Source Type: research

Second-Generation Visually Guided Laser Balloon Ablation System for Pulmonary Vein Isolation: Learning Curve, Safety and Efficacy  - The MERLIN Registry.
CONCLUSIONS: The LB2 was safe and effective for PVI, even for operators without any previous experience in laser balloon-based PVI. Procedure time, left atrial dwelling time and fluoroscopy time decreased after a learning curve of 15 cases. PMID: 31708555 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - November 9, 2019 Category: Cardiology Authors: Heeger CH, Phan HL, Meyer-Saraei R, Fink T, Sciacca V, Liosis S, Brüggemann B, Große N, Fahimi B, Sano M, Kuck KH, Ouyang F, Vogler J, Eitel C, Tilz RR Tags: Circ J Source Type: research

Guidelines for Atrial Fibrillation Treatment to Avoid Stroke Should Be Established for Each Region/Ethnicity.
PMID: 31708556 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - November 9, 2019 Category: Cardiology Authors: Shinohara T, Takahashi N Tags: Circ J Source Type: research

Absorb GT1 Bioresorbable Vascular Scaffold System  - 1-Year Post-Marketing Surveillance in Japan.
CONCLUSIONS: Appropriate OCT-guided BVS implantation may prevent incomplete strut apposition, thereby reducing the risk of target lesion failure and scaffold thrombosis. PMID: 31708522 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - November 8, 2019 Category: Cardiology Authors: Suzuki N, Kozuma K, Nakamura S, Aramaki K, Saito S, Shibata Y, Nanasato M, Fujii K, Kusano H, Ediebah D, Nakamura M Tags: Circ J Source Type: research

H2FPEF Score for the Prediction of Exercise Intolerance and Abnormal Hemodynamics in Japanese  - Evaluation by Exercise Stress Echocardiography Combined With Cardiopulmonary Exercise Testing.
H2FPEF Score for the Prediction of Exercise Intolerance and Abnormal Hemodynamics in Japanese - Evaluation by Exercise Stress Echocardiography Combined With Cardiopulmonary Exercise Testing. Circ J. 2019 Nov 08;: Authors: Takahari K, Hidaka T, Ueda Y, Izumi K, Harada Y, Susawa H, Kinoshita M, Itakura K, Utsunomiya H, Kihara Y Abstract BACKGROUND: Both the H2FPEF-score and nomogram-score, which consist of simple clinical parameters, can assist in diagnosing "early" heart failure with preserved ejection fraction (HFpEF) and only exertional dyspnea, but their these usefulness in Japanese rema...
Source: Circulation Journal - November 8, 2019 Category: Cardiology Authors: Takahari K, Hidaka T, Ueda Y, Izumi K, Harada Y, Susawa H, Kinoshita M, Itakura K, Utsunomiya H, Kihara Y Tags: Circ J Source Type: research

Guideline-Adherent Treatment for Stroke and Death in Atrial Fibrillation Patients From UK and Japanese AF Registries.
CONCLUSIONS: Approximately half of the AF patients received optimal ATT according to guideline recommendations, which was associated with a lower risk of stroke. Furthermore, there was no interaction for the 2 populations and the influence of ATT adherence. PMID: 31694989 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - November 6, 2019 Category: Cardiology Authors: Miyazawa K, Ogawa H, Mazurek M, Shantsila E, Lane DA, Wolff A, Akao M, Lip GYH Tags: Circ J Source Type: research

Development of a Novel Algorithm to Detect Atrial Fibrillation Using an Automated Blood Pressure Monitor With an Irregular Heartbeat Detector.
CONCLUSIONS: The novel algorithm with 3 BP measurements using the Omron automated BP monitor with IHB detector showed high sensitivity and specificity for diagnosing AF in general cardiac patients. PMID: 31685781 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - November 2, 2019 Category: Cardiology Authors: Ishizawa M, Noma T, Izumi T, Tani R, Inoue T, Nasu E, Tobiume A, Hasui Y, Yokoyama S, Hamaya H, Ishikawa S, Matsunaga K, Kawakami R, Konishi K, Miyake Y, Ishikawa K, Tsuji T, Murakami K, Nishimoto N, Kitajima H, Minamino T Tags: Circ J Source Type: research

What Is the Rationale for Utilizing Bilateral Internal Thoracic Arteries in Concomitant Cardiac Operations?
PMID: 31685783 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - November 1, 2019 Category: Cardiology Authors: Takemura H Tags: Circ J Source Type: research

CORRIGENDUM: Survey of Palliative Sedation at End of Life in Terminally Ill Heart Failure Patients  - A Single-Center Experience of 5-Year Follow-up.
CORRIGENDUM: Survey of Palliative Sedation at End of Life in Terminally Ill Heart Failure Patients - A Single-Center Experience of 5-Year Follow-up. Circ J. 2019;83(11):2389 Authors: Hamatani Y, Nakai E, Nakamura E, Miyata M, Kawano Y, Takada Y, Anchi Y, Funabashi S, Hirayama A, Kuroda K, Amano M, Sugano Y, Anzai T, Izumi C PMID: 31656274 [PubMed - in process] (Source: Circulation Journal)
Source: Circulation Journal - October 29, 2019 Category: Cardiology Authors: Hamatani Y, Nakai E, Nakamura E, Miyata M, Kawano Y, Takada Y, Anchi Y, Funabashi S, Hirayama A, Kuroda K, Amano M, Sugano Y, Anzai T, Izumi C Tags: Circ J Source Type: research

Efficacy of a Device-Based Continuous Optimization Algorithm for Patients With Cardiac Resynchronization Therapy.
This study investigated the clinical effect of the aCRT algorithm, especially in mildly wide QRS (120≤QRS
Source: Circulation Journal - October 26, 2019 Category: Cardiology Authors: Ueda N, Noda T, Ishibashi K, Nakajima K, Kataoka N, Kamakura T, Wada M, Yamagata K, Inoue Y, Miyamoto K, Nagase S, Aiba T, Kanzaki H, Izumi C, Noguchi T, Yasuda S, Kusano K Tags: Circ J Source Type: research

Tribute to Paul M. Vanhoutte, MD, PhD  - 1940-2019.
Tribute to Paul M. Vanhoutte, MD, PhD - 1940-2019. Circ J. 2019 Oct 25;: Authors: Shimokawa H, Nagao T, Komori K PMID: 31656271 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - October 25, 2019 Category: Cardiology Authors: Shimokawa H, Nagao T, Komori K Tags: Circ J Source Type: research

Cathepsin S-Mediated Negative Regulation of Wnt5a/SC35 Activation Contributes to Ischemia-Induced Neovascularization in Aged Mice.
CONCLUSIONS: These findings demonstrated that the impairment of ischemia-induced neovascularization in aged CatS-/-mice is due, at least in part, to the attenuation of endothelial cell/EPC functions and/or mobilization associated with Wnt5a/SC35 activation in advanced age. PMID: 31645525 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - October 24, 2019 Category: Cardiology Authors: Xu W, Yu C, Piao L, Inoue A, Wang H, Meng X, Li X, Cui L, Umegaki H, Shi GP, Murohara T, Kuzuya M, Cheng XW Tags: Circ J Source Type: research

Association Between Prehospital Supraglottic Airway Compared With Bag-Mask Ventilation and Glasgow-Pittsburgh Cerebral Performance Category 1 in Patients With Out-of-Hospital Cardiac Arrest.
CONCLUSIONS: Our results indicated that compared with BLS, patients in the prehospital SGA and/or epinephrine groups had a significantly reduced incidence of CPC 1 status. PMID: 31645507 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - October 22, 2019 Category: Cardiology Authors: Jinno K, Hifumi T, Okazaki T, Kuroda Y, Tahara Y, Yonemoto N, Nonogi H, Nagao K, Ikeda T, Sato N, Tsutsui H, Japanese Circulation Society Resuscitation Science Study (JCS-ReSS) Group Tags: Circ J Source Type: research

Prevalence and Clinical Significance of Layered Plaque in Patients With Stable Angina Pectoris  - Evaluation With Histopathology and Optical Coherence Tomography.
Prevalence and Clinical Significance of Layered Plaque in Patients With Stable Angina Pectoris - Evaluation With Histopathology and Optical Coherence Tomography. Circ J. 2019 Oct 22;: Authors: Okamoto H, Kume T, Yamada R, Koyama T, Tamada T, Imai K, Neishi Y, Uemura S Abstract BACKGROUND: Healed plaques are identified as a layered pattern with optical coherence tomography (OCT) imaging, but the exact relationship between healed plaques and the development of significant coronary stenosis in stable angina pectoris (SAP) is not fully understood.Methods and Results:A retrospective clinincal study i...
Source: Circulation Journal - October 22, 2019 Category: Cardiology Authors: Okamoto H, Kume T, Yamada R, Koyama T, Tamada T, Imai K, Neishi Y, Uemura S Tags: Circ J Source Type: research

Detection of Active Inflammation Status Around Ventricular Aneurysms in Patients With Cardiac Sarcoidosis.
CONCLUSIONS: A pattern of strong 18F-FDG accumulation surrounding the VA and its disappearance in the VA center might be characteristic in patients with CS complicated by VA. Careful attention to FDG uptake would further elucidate CS pathophysiology and aid in the early treatment of VA. PMID: 31631075 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - October 19, 2019 Category: Cardiology Authors: Nanno T, Kobayashi S, Yoshitomi R, Fujii S, Kajii T, Kohno M, Ishiguchi H, Okuda S, Okada M, Suga K, Yano M Tags: Circ J Source Type: research

Cardiac Rupture Due to Side Branch Occlusion After Stent Implantation  - The Crime of Jailed Stent.
Cardiac Rupture Due to Side Branch Occlusion After Stent Implantation - The Crime of Jailed Stent. Circ J. 2019 Oct 18;: Authors: Asakura K, Homma T, Akutsu N, Fukamachi D, Ozaki S, Ohta H, Okumura Y, Hao H PMID: 31631077 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - October 18, 2019 Category: Cardiology Authors: Asakura K, Homma T, Akutsu N, Fukamachi D, Ozaki S, Ohta H, Okumura Y, Hao H Tags: Circ J Source Type: research

Postconditioning Accelerates Myocardial Inflammatory Resolution Demonstrated by 14C-Methionine Imaging and Attenuates Ventricular Remodeling After Ischemia and Reperfusion.
Abstract BACKGROUND: Methionine uptake after myocardial infarction has been proven to reflect myocardial inflammation. The effect of postconditioning on the post-infarction inflammatory process, however, remains to be elucidated.Methods and Results:In control (n=22) and postconditioning rats (n=23), the left coronary artery was occluded for 30 min, followed by reperfusion for 1, 3, 7, and 14 days. Postconditioning was performed immediately following the reperfusion. 14C-methinine (0.74 MBq) and 201Tl (14.8 MBq) were injected 20 and 10 min prior to sacrifice, respectively. One minute before sacrifice, 150-180 M...
Source: Circulation Journal - October 17, 2019 Category: Cardiology Authors: Taki J, Inaki A, Wakabayashi H, Matsunari I, Imanaka-Yoshida K, Ogawa K, Hiroe M, Shiba K, Kinuya S Tags: Circ J Source Type: research

Prevalence and Associated Stroke Risk of Human Immunodeficiency Virus-Infected Patients With Atrial Fibrillation  - A Nationwide Cohort Study.
CONCLUSIONS: The risks of ischemic stroke/SE and major bleeding were significantly higher in HIV-infected patients compared with non-HIV-infected patients with AF. Despite this, the actual use of OACs among AF patients with HIV was suboptimal. PMID: 31619594 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - October 17, 2019 Category: Cardiology Authors: Jung H, Yang PS, Jang E, Yu HT, Kim TH, Uhm JS, Kim JY, Sung JH, Pak HN, Lee MH, Lip GYH, Joung B Tags: Circ J Source Type: research

Current Status and Clinical Outcomes of Oral Anticoagulant Discontinuation After Ablation for Atrial Fibrillation in Japan  - Findings From the AF Frontier Ablation Registry.
CONCLUSIONS: Although the incidences of stroke/TIA, major bleeding, and death were relatively low among patients for whom OAC therapy was discontinued, stroke/TIA occurrence was strongly associated with a high baseline stroke risk rather than with OAC status. Thus, discontinuation of OAC therapy requires careful consideration, especially in patients with a high baseline stroke risk. PMID: 31619591 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - October 16, 2019 Category: Cardiology Authors: Okumura Y, Nagashima K, Arai M, Watanabe R, Yokoyama K, Matsumoto N, Otsuka T, Suzuki S, Hirata A, Murakami M, Takami M, Kimura M, Fukaya H, Nakahara S, Kato T, Shimizu W, Iwasaki YK, Hayashi H, Harada T, Nakajima I, Okumura K, Koyama J, Tokuda M, Yamane Tags: Circ J Source Type: research

Diagnostic Performance of High-Resolution Intravascular Ultrasound for the Detection of Plaque Rupture in Patients With Acute Coronary Syndrome.
CONCLUSIONS: HR-IVUS had high sensitivity, but modest specificity for identifying OCT-derived plaque rupture. Compared with results from previous conventional IVUS studies, HR-IVUS might have increased ability to detect OCT-derived plaque rupture, but there is still substantial scope for improvement, especially in the specificity. PMID: 31611536 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - October 12, 2019 Category: Cardiology Authors: Ohashi H, Ando H, Takashima H, Waseda K, Shimoda M, Fujimoto M, Sawada H, Suzuki A, Sakurai S, Nakano Y, Amano T Tags: Circ J Source Type: research

Association of Echocardiography Before Major Elective Non-Cardiac Surgery With Improved Postoperative Outcomes  - Possible Implications for Patient Care.
CONCLUSIONS: The use of echocardiography in elderly patients with certain risk factors was associated with improved postoperative outcomes. The basis for this finding remains to be determined; particularly whether echocardiography is simply a marker of a population with better outcomes or whether it leads to better management that improves outcomes. PMID: 31611537 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - October 12, 2019 Category: Cardiology Authors: Kusunose K, Torii Y, Yamada H, Nishio S, Hirata Y, Saijo Y, Ise T, Yamaguchi K, Fukuda D, Yagi S, Soeki T, Wakatsuki T, Sata M Tags: Circ J Source Type: research

What We Know and What We Don't Know About the Adaptation to Pregnancy and Left Ventricular Diastolic Dysfunction.
PMID: 31611538 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - October 12, 2019 Category: Cardiology Authors: Kawamatsu N, Ishizu T, Kawakami Y Tags: Circ J Source Type: research

Kazuo Yamada, MD, PhD  - 1924-2019.
Kazuo Yamada, MD, PhD - 1924-2019. Circ J. 2019 Oct 12;: Authors: Toyama J PMID: 31611539 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - October 12, 2019 Category: Cardiology Authors: Toyama J Tags: Circ J Source Type: research

MitraClip Therapy for Healed Infective Endocarditis  - How Long Should We Wait After Active Infection?
MitraClip Therapy for Healed Infective Endocarditis - How Long Should We Wait After Active Infection? Circ J. 2019 Oct 10;: Authors: Kato Y, Amaki M, Kanzaki H, Kataoka Y, Okada A, Miyamoto K, Hamatani Y, Amano M, Takahama H, Hasegawa T, Matsumoto Y, Fujita T, Kobayashi J, Ishibashi-Ueda H, Yasuda S, Izumi C PMID: 31597888 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - October 10, 2019 Category: Cardiology Authors: Kato Y, Amaki M, Kanzaki H, Kataoka Y, Okada A, Miyamoto K, Hamatani Y, Amano M, Takahama H, Hasegawa T, Matsumoto Y, Fujita T, Kobayashi J, Ishibashi-Ueda H, Yasuda S, Izumi C Tags: Circ J Source Type: research

Hitting Two Birds With One Stone  - Pre-Existing Paravalvular Leak Closed by Valve-in-Valve Implantation.
Hitting Two Birds With One Stone - Pre-Existing Paravalvular Leak Closed by Valve-in-Valve Implantation. Circ J. 2019 Oct 10;: Authors: Osoble AA, Kumar A, Bartel T PMID: 31597889 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - October 10, 2019 Category: Cardiology Authors: Osoble AA, Kumar A, Bartel T Tags: Circ J Source Type: research

JCS 2016 Guideline on Diagnosis and Treatment of Cardiac Sarcoidosis  - Digest Version.
JCS 2016 Guideline on Diagnosis and Treatment of Cardiac Sarcoidosis - Digest Version. Circ J. 2019 Oct 09;: Authors: Terasaki F, Azuma A, Anzai T, Ishizaka N, Ishida Y, Isobe M, Inomata T, Ishibashi-Ueda H, Eishi Y, Kitakaze M, Kusano K, Sakata Y, Shijubo N, Tsuchida A, Tsutsui H, Nakajima T, Nakatani S, Horii T, Yazaki Y, Yamaguchi E, Yamaguchi T, Ide T, Okamura H, Kato Y, Goya M, Sakakibara M, Soejima K, Nagai T, Nakamura H, Noda T, Hasegawa T, Morita H, Ohe T, Kihara Y, Saito Y, Sugiyama Y, Morimoto SI, Yamashina A, Japanese Circulation Society Joint Working Group PMID: 31597819 [PubMed - as supplied...
Source: Circulation Journal - October 9, 2019 Category: Cardiology Authors: Terasaki F, Azuma A, Anzai T, Ishizaka N, Ishida Y, Isobe M, Inomata T, Ishibashi-Ueda H, Eishi Y, Kitakaze M, Kusano K, Sakata Y, Shijubo N, Tsuchida A, Tsutsui H, Nakajima T, Nakatani S, Horii T, Yazaki Y, Yamaguchi E, Yamaguchi T, Ide T, Okamura H, Kat Tags: Circ J Source Type: research

Coronary Artery Features of Immunoglobulin-G4-Related Coronary Periarteritis With Multi-Modality Visualization.
PMID: 31582647 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - October 3, 2019 Category: Cardiology Authors: Sudo M, Fukamachi D, Yoda S, Okumura Y Tags: Circ J Source Type: research

Successful Disruption of Massive Calcified Nodules Using Novel Shockwave Intravascular Lithotripsy.
PMID: 31582648 [PubMed - as supplied by publisher] (Source: Circulation Journal)
Source: Circulation Journal - October 3, 2019 Category: Cardiology Authors: Warisawa T, Salazar CH, Gonzalo N, Akashi YJ, Escaned J Tags: Circ J Source Type: research