Pancreaticoduodenal arcades as salvage route for transarterial embolization of life-threatening hepatic hemorrhage in patients with severe celiac axis stenosis: Case series
ConclusionEndovascular management of massive hepatic hemorrhage in cases of inaccessibility to hepatic arteries through CA is a highly challenging situation in which the technical success depends on the operator experience, choice of the material and anatomical knowledge of hepatic arterial collateral supply. (Source: International Journal of Surgery Case Reports)
Source: International Journal of Surgery Case Reports - July 6, 2018 Category: Surgery Source Type: research

The subjective experience of subjects diagnosed with celiac disease in adulthood
ConclusionThe results show the importance of developing a “mythology” (concerning the disease's origin) to enable the inclusion of the condition in the individual's on-going personal story.RésuméIntroductionLa prévalence de la maladie cœliaque serait de 1/100 à 1/300 auprès des sujets de type caucasien. Si de nombreuses études quantitatives se sont intéressées aux difficultés rencontrées par les patients, peu de recherches ont questionné l’expérience subjective et le vécu de la maladie cœliaque.ObjectifL...
Source: European Review of Applied Psychology - July 5, 2018 Category: Psychiatry & Psychology Source Type: research

Rapid, Loop-Mediated Isothermal Amplification Detection of Celiac Disease Risk Alleles
Publication date: May 2018Source: The Journal of Molecular Diagnostics, Volume 20, Issue 3Author(s): Michael Erlichster, Jason A. Tye-Din, Michael D. Varney, Efstratios Skafidas, Patrick KwanHuman leukocyte antigen (HLA) genotyping has become a useful investigation in the diagnostic work-up of celiac disease (CD), with utility in risk stratification and screening. However, broad application of this technology has been hindered by the cost and time burden of conventional laboratory-based assays. We have developed and validated CD–loop-mediated isothermal amplification (CD-LAMP), a LAMP assay, which enables rapid ident...
Source: The Journal of Molecular Diagnostics - July 5, 2018 Category: Pathology Source Type: research

Are the dietary habits of treated individuals with celiac disease adherent to a Mediterranean diet?
Publication date: Available online 4 July 2018Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): F. Morreale, C. Agnoli, L. Roncoroni, S. Sieri, V. Lombardo, T. Mazzeo, L. Elli, M.T. Bardella, C. Agostoni, L. Doneda, A. Scriciolo, F. Brighenti, N. PellegriniAbstractBackground and AimsThe only treatment for celiac disease (CD) is strict, lifelong adherence to a gluten-free (GF) diet. To date, there are contrasting data concerning the nutritional adequacy of GF products and diet. There have been no studies that have assessed the adherence of individuals with CD to a Mediterranean diet (MD), a protective diet...
Source: Nutrition, Metabolism and Cardiovascular Diseases - July 5, 2018 Category: Nutrition Source Type: research

Addressing Barriers for Patients with Celiac Disease When Assessing for Gluten in Medications
Publication date: Available online 5 June 2018Source: Journal of the Academy of Nutrition and DieteticsAuthor(s): Georgina Rubal-Peace, Caroline Sepp (Source: Journal of the Academy of Nutrition and Dietetics)
Source: Journal of the Academy of Nutrition and Dietetics - July 5, 2018 Category: Nutrition Source Type: research

A difficult diagnosis of coeliac disease: Repeat duodenal histology increases diagnostic yield in patients with concomitant causes of villous atrophy
We report a case of a woman with anaemia, weight loss and diarrhoea with an initial diagnosis of seronegative CD and a histological documented villous atrophy who did not improve on gluten-free diet due to the concomitant presence of common variable immunodeficiency (CVID) and Giardia lamblia infection. This case report confirms that CD diagnosis in CVID patients is difficult; the combination of anti-endomysial antibodies (EmA-IgA), anti-tissue transglutaminase antibodies (tTG-IgAb) antibodies and total IgA is obligatory in basic diagnostic of CD but in CVID are negative. Furthermore, the typical histological aspects of th...
Source: Arab Journal of Gastroenterology - July 5, 2018 Category: Gastroenterology Source Type: research

Tracking celiac disease-triggering peptides and whole wheat flour quality as function of germination kinetics
Publication date: October 2018Source: Food Research International, Volume 112Author(s): Fatma Boukid, Barbara Prandi, Elena Vittadini, Enrico Francia, Stefano SforzaAbstractGermination is already a well-accepted process by consumers with many products made from sprouted seeds or containing limited amounts of flour form sprouted grains. The present work aimed assessing the usefulness of germination in reducing gluten peptides associated with celiac disease, at the same time evaluating some technological features of the obtained germinated wheat. In the first part of the work, celiac disease (CD)-triggering peptides were tra...
Source: Food Research International - July 5, 2018 Category: Food Science Source Type: research

Reactivity of gluten proteins from spelt and bread wheat accessions towards A1 and G12 antibodies in the framework of celiac disease
Publication date: 1 December 2018Source: Food Chemistry, Volume 268Author(s): Emmanuelle Escarnot, Sébastien Gofflot, Georges Sinnaeve, Benjamin Dubois, Pierre Bertin, Dominique MingeotAbstractIn the framework of celiac disease, this research aims at evaluating the reactivity of 195 wheat accessions and 240 spelt accessions to A1 and G12 monoclonal antibodies. A great variability in reactivity was found among the accessions of both subspecies. On average, spelt showed very slightly higher reactivity than wheat but accessions with low reactivity were encountered in both subspecies. In both wheat and spelt, there was ...
Source: Food Chemistry - July 5, 2018 Category: Food Science Source Type: research

Effects of transglutaminase on health properties of food products
Publication date: August 2018Source: Current Opinion in Food Science, Volume 22Author(s): Shabboo Amirdivani, Nasim Khorshidian, Marina Fidelis, Daniel Granato, Mohammad Reza Koushki, Mehrdad Mohammadi, Khadijeh Khoshtinat, Amir Mohammad MortazavianNowadays, food manufacturers try to develop new products with unique functional characteristics; however, these products have not always been to the benefit of the consumer and in some cases have led to consumer's health problems. The use of transglutaminase (TG) in the food industry is very common. Transglutaminase catalyzes covalent bond between lysine and glutamine in peptide...
Source: Current Opinion in Food Science - July 5, 2018 Category: Food Science Source Type: research

Are the dietary habits of treated individuals with celiac disease adherent to a Mediterranean diet?
Conclusion The results raise questions concerning the food choices of individuals with CD suggesting the need of encouraging them to make better food choices more in line with an MD, which would improve their nutritional status and better protect them from NCDs at long term. Protocol registration ClinicalTrials.gov (ID NCT01975155) on November 4 2013. (Source: Nutrition, Metabolism and Cardiovascular Diseases)
Source: Nutrition, Metabolism and Cardiovascular Diseases - July 5, 2018 Category: Nutrition Source Type: research

T cells in coeliac disease: a rational target for diagnosis and therapy
T cells in coeliac disease: a rational target for diagnosis and therapyT cells in coeliac disease: a rational target for diagnosis and therapy, Published online: 04 July 2018; doi:10.1038/s41575-018-0043-4New findings show that disease-specific T cells that target gluten in patients with coeliac disease persist for decades. The data highlight a central role for a highly select and stable population of T cells in disease persistence and support the feasibility of diagnostics and therapies targeting these cells. (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - July 4, 2018 Category: Gastroenterology Authors: Melinda Y. Hardy Jason A. Tye-Din Source Type: research

The elusive case of human intraepithelial T cells in gut homeostasis and inflammation
The elusive case of human intraepithelial T cells in gut homeostasis and inflammation, Published online: 04 July 2018; doi:10.1038/s41575-018-0039-0Intraepithelial T cells (IETs) are a unique collection of T cells located at the epithelial barrier. This Review highlights the role of these cells in gut homeostasis and disease, including coeliac disease and IBD. Targeting of IETs in therapeutic interventions is also discussed. (Source: Nature Reviews Gastroenterology and Hepatology)
Source: Nature Reviews Gastroenterology and Hepatology - July 4, 2018 Category: Gastroenterology Authors: Lisanne Lutter David P. Hoytema van Konijnenburg Eelco C. Brand Bas Oldenburg Femke van Wijk Source Type: research

Towards an individual screening strategy for first-degree relatives of celiac patients
AbstractCeliac disease (CD) is known to be more prevalent in first-degree relatives of patients. In this retrospective cohort study of 609 relatives between 1994 and 2016, we investigated the effect of sex, HLA type, and age at time of index celiac diagnosis. Pearson ’s chi-square test and Kaplan-Meier survival analysis were used as statistical analyses. CD screening was carried out for 427 relatives (70%), resulting in a prevalence of 15%. HLA typing in 335 relatives showed HLA-DQ2/DQ8 positivity in 87.5%. In 63% of children and all parents, celiac disease wa s diagnosed at first screening. It was diagnosed signific...
Source: European Journal of Pediatrics - July 4, 2018 Category: Pediatrics Source Type: research

Are the dietary habits of treated individuals with celiac disease adherent to a Mediterranean diet?
The only treatment for celiac disease (CD) is strict, lifelong adherence to a gluten-free (GF) diet. To date, there are contrasting data concerning the nutritional adequacy of GF products and diet. There have been no studies that have assessed the adherence of individuals with CD to a Mediterranean diet (MD), a protective dietary regimen against major non-communicable diseases (NCDs). Therefore, we examined the adherence to an MD of a group of Italian individuals with CD and compared it with that of a healthy control group. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 4, 2018 Category: Nutrition Authors: F. Morreale, C. Agnoli, L. Roncoroni, S. Sieri, V. Lombardo, T. Mazzeo, L. Elli, M.T. Bardella, C. Agostoni, L. Doneda, A. Scriciolo, F. Brighenti, N. Pellegrini Source Type: research

Granular IgA Deposits in the Skin of Patients with Coeliac Disease: Is it Always Dermatitis Herpetiformis?
In conclusion, IgA deposits may be considered an immunopathological marker for coeliac disease; therefore, patients with coeliac disease showing skin manifestations with positive direct immunofluorescence should be investigated carefully in order to make a differential diagnosis between dermatitis herpetiformis and other non-dermatitis herpetiformis inflammatory skin diseases. PMID: 29972219 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - July 4, 2018 Category: Dermatology Authors: Bonciolini V, Antiga E, Bianchi B, Del Bianco E, Ninci A, Maio V, Pimpinelli N, Caproni M Tags: Acta Derm Venereol Source Type: research

Impact of reflective supervision on early childhood interventionists ’ perceptions of self‐efficacy, job satisfaction, and job stress
Infant Mental Health Journal, EarlyView. (Source: Infant Mental Health Journal)
Source: Infant Mental Health Journal - July 3, 2018 Category: Child Development Authors: Cynthia A.Frosch , ZubedaVarwani , JuliaMitchell , CeliaCaraccioli , MatthewWilloughby Source Type: research

Reversal of the Jejunoileal Fold in Celiac Disease
Radiology,Volume 288, Issue 2, Page 342-342, August 2018. (Source: Radiology)
Source: Radiology - July 3, 2018 Category: Radiology Authors: Reem Mimish Caroline Reinhold Source Type: research

Celiac disease gene expression data can be used to classify biopsies along the Marsh score severity scale.
Journal of Gastroenterology and Hepatology,Volume 0, Issue ja, -Not available-. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - July 2, 2018 Category: Gastroenterology Authors: Richard P GCharlesworth , Linda LAgnew , David RScott , Nicholas MAndronicos Source Type: research

Immunohistochemical Expression of Antitissue Transglutaminase 2 in Tissue Injuries: An Interpretation Beyond Celiac Disease
In conclusion, IHC expression of anti-TG2 stain correlates with both acute and chronic tissue injuries, irrespective of etiology and organ involvement. It is not a reliable marker for diagnosis of CeD. (Source: Applied Immunohistochemistry and Molecular Morphology)
Source: Applied Immunohistochemistry and Molecular Morphology - July 1, 2018 Category: Chemistry Tags: Research Articles Source Type: research

Tracking celiac disease-triggering peptides and whole wheat flour quality as function of germination kinetics
Publication date: October 2018 Source:Food Research International, Volume 112 Author(s): Fatma Boukid, Barbara Prandi, Elena Vittadini, Enrico Francia, Stefano Sforza Germination is already a well-accepted process by consumers with many products made from sprouted seeds or containing limited amounts of flour form sprouted grains. The present work aimed assessing the usefulness of germination in reducing gluten peptides associated with celiac disease, at the same time evaluating some technological features of the obtained germinated wheat. In the first part of the work, celiac disease (CD)-triggering peptides were tracked ...
Source: Food Research International - July 1, 2018 Category: Food Science Source Type: research

Sick to the stomach - A case of open surgical decompression of coeliac and superior mesenteric arteries by division of the median arcuate ligament
Introduction: Median Arcuate Ligament (MAL) Syndrome is a rare vascular phenomenon typified by the paradigm of weight loss, post-prandial pain, and bowel dysfunction. A diagnosis of exclusion, with an incidence of 2 per 100,000 patients1, it reflects anatomical variation of the MAL and/or coeliac arteries. (Source: International Journal of Surgery)
Source: International Journal of Surgery - July 1, 2018 Category: Surgery Authors: M. Montague, R. Elkady, S. Sultan Source Type: research

The coexistence of neurofibromatosis type I and celiac disease in a child.
PMID: 30249573 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - July 1, 2018 Category: Gastroenterology Authors: Işık İA, Akbulut UE Tags: Turk J Gastroenterol Source Type: research

In extremis diagnosis of celiac disease and concomitant wheat allergy.
We describe a peculiar case of a young female patient affected by wheat allergy whose serological and histological data were not diagnostic for CD. Organ culture system successfully detected specific antibodies for CD in duodenal biopsy supernatant, supporting the diagnosis of CD. PMID: 30249570 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - July 1, 2018 Category: Gastroenterology Authors: Borghini R, Donato G, Marino M, Casale R, Tola MD, Picarelli A Tags: Turk J Gastroenterol Source Type: research

Physicians' attitude and perception regarding celiac disease: A questionnaire-based study.
CONCLUSION: This study highlights poor awareness among the physicians' in regard to important CD features and diagnostic recommendations in adult patients. More efforts are warranted to improve awareness on CD features among physicians of different medical specialties. PMID: 30249556 [PubMed - in process] (Source: The Turkish Journal of Gastroenterology)
Source: The Turkish Journal of Gastroenterology - July 1, 2018 Category: Gastroenterology Authors: Jinga M, Popp A, Balaban DV, Dima A, Jurcut C Tags: Turk J Gastroenterol Source Type: research

Concurrent extrapulmonary bronchopulmonary sequestration and bronchogenic cyst
Publication date: July 2018 Source:Journal of Pediatric Surgery Case Reports, Volume 34 Author(s): Lindel Dewberry, Jason Bunn, Csaba Galambos, Henry L. Galan, Michael V. Zaretsky, Nicholas Behrendt, Regina Reynolds, Mariana Meyers, Ahmed I. Marwan, Kenneth W. Liechty A prenatal ultrasound (US) at 21 weeks estimated gestational age (EGA) identified a left intrathoracic homogenously echogenic microcystic mass with mediastinal shift and a CPAM volume ratio (CVR) of 0.78 (Fig. 1). A fetal magnetic resonance imaging (MRI) study confirmed the US findings. MRI and US were repeated at 35 weeks EGA demonstrating a CVR of 0.36 and...
Source: Journal of Pediatric Surgery Case Reports - June 30, 2018 Category: Surgery Source Type: research

There is no such thing as a (gluten-)free lunch: Higher food prices and the cost for coeliac consumers.
Abstract A lifelong gluten-free diet is the only available treatment for coeliac disease at present. However, the high price of gluten-free substitute foods is likely to generate a welfare loss for consumers who drop gluten from their diet. Using original data on retail prices in four major UK supermarkets and consumption data from the UK Living Cost and Food Survey, we simulate the welfare change associated to a switch to the gluten-free diet. Within the "Bread and Cereals" category, retail price data show that the average price of gluten-free products is £1.12/100g relative to £ 0.59/100g o...
Source: Economics and Human Biology - June 30, 2018 Category: Biology Authors: Capacci S, Leucci AC, Mazzocchi M Tags: Econ Hum Biol Source Type: research

Screening for autoimmune thyroiditis and celiac disease in minority children with type 1 diabetes
Journal Name: Journal of Pediatric Endocrinology and Metabolism Issue: Ahead of print (Source: Journal of Pediatric Endocrinology and Metabolism)
Source: Journal of Pediatric Endocrinology and Metabolism - June 27, 2018 Category: Endocrinology Source Type: research

Screening for Celiac Disease in Children with Down Syndrome
Category/Date: Emerging Knowledge for Clinical Practice Podium Presentations focusing on the Research Agenda Priority of Clinical Priorities in Health Promotion and Disease Prevention, Presented at NAPNAP's 39th National Conference on Pediatric Health Care, March 20, 2018, Chicago, IL. (Source: Journal of Pediatric Health Care)
Source: Journal of Pediatric Health Care - June 27, 2018 Category: Pediatrics Authors: Dee A. Daniels, Juana Marmolejo, Edwin Liu, Garret Prince, Kristy Wolter-Warmerdam, Fran Hickey Source Type: research

Novel steps forward in the histopathology of non-celiac gluten sensitivity, authors ’ reply
(Source: Virchows Archiv)
Source: Virchows Archiv - June 27, 2018 Category: Pathology Source Type: research

Screening for autoimmune thyroiditis and celiac disease in minority children with type 1 diabetes
Journal Name: Journal of Pediatric Endocrinology and Metabolism Volume: 31 Issue: 8 Pages: 879-885 (Source: Journal of Pediatric Endocrinology and Metabolism)
Source: Journal of Pediatric Endocrinology and Metabolism - June 27, 2018 Category: Endocrinology Source Type: research

Impact of Thyroid Autoimmunity on Thyroid Function in 12-year-old Children With Celiac Disease
Conclusions: The risk of thyroid dysfunction due to thyroid autoimmunity is larger for those with CD than their healthy peers. Our study indicates that a gluten-free diet does not reduce the risk of thyroid dysfunction. Further studies are required for improved understanding of the role of the gluten-free diet for the risk of autoimmune diseases in children with CD. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 26, 2018 Category: Gastroenterology Tags: Original Articles: Gastroenterology: Celiac Disease Source Type: research

Creation of Experience-based Celiac Benchmarks: The First Step in Pretransition Self-management Assessment
Conclusions: This novel patient-centered celiac skill list may improve anticipatory guidance and accelerate self-management skills. (Source: Journal of Pediatric Gastroenterology and Nutrition)
Source: Journal of Pediatric Gastroenterology and Nutrition - June 26, 2018 Category: Gastroenterology Tags: Original Articles: Gastroenterology: Celiac Disease Source Type: research

[Primary eosinophilic colitis in a celiac patient].
We describe the case of a patient with well-controlled celiac disease and chronic diarrhea of indeterminate origin. The final diagnosis was eosinophilic colitis. A complete response was obtained when she was treated with oral budesonide. Nowadays she remains asymptomatic. PMID: 29943760 [PubMed - as supplied by publisher] (Source: Anales del Sistema Sanitario de Navarra)
Source: Anales del Sistema Sanitario de Navarra - June 25, 2018 Category: General Medicine Authors: Ostiz M, Zelaya MV, Laiglesia M, Campillo A, Kutz M, León-Brito H Tags: An Sist Sanit Navar Source Type: research

Transient elevation of anti-transglutaminase and anti-endomysium antibodies in Giardia infection.
In this report, we describe eight cases with elevated CeD serological markers and pathological duodenal histology during, or shortly after, Giardia infection. We present follow-up clinical and serological findings to determine which of these that were diagnosed with CeD. Serum levels of tTGand EMA did not discriminate well between patients where CeD was excluded, and those who were later diagnosed with CeD. The value of these serological CeD markers is discussed in relation to CeD diagnosis in cases with chronic or recent giardiasis. PMID: 29911457 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - June 19, 2018 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Children with untreated coeliac disease have sub-clinical cardiac dysfunction: a longitudinal observational analysis.
CONCLUSIONS: Subclinical cardiac dysfunction is common in CD children at diagnosis. Improvement in echocardiographic parameters occurs with GFD and non-compliant children continue to have persistent cardiac dysfunction. PMID: 29909690 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - June 19, 2018 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Paper based analytical device modified with nanoporous material for the fluorescent sensing of gliadin content in different food samples
Publication date: November 2018 Source:Microchemical Journal, Volume 142 Author(s): Evelyn Marín-Barroso, Cristian M. Moreira, Germán A. Messina, Franco A. Bertolino, Mara Alderete, Galo J.A.A. Soler-Illia, Julio Raba, Sirley V. Pereira A novel fluorescent paper based immunosensor for the quantification of gliadin content in different food samples was constructed. The device consists of a paper platform modified with amino functionalized mesoporous material. The nanoporous structure and the aminofunctionality increased the anti-gliadin antibodies immobilization capacity of the sensing surface, conferring hig...
Source: Microchemical Journal - June 19, 2018 Category: Chemistry Source Type: research

Screening for coeliac disease in children
Acta Paediatrica,Volume 0, Issue ja, -Not available-. (Source: Acta Paediatrica)
Source: Acta Paediatrica - June 19, 2018 Category: Pediatrics Authors: Laura Kivel ä , Kalle Kurppa Source Type: research

Novel steps forward in the histopathology of non-celiac gluten sensitivity
(Source: Virchows Archiv)
Source: Virchows Archiv - June 18, 2018 Category: Pathology Source Type: research

Addressing Barriers for Patients with Celiac  Disease When Assessing for Gluten in Medications
Publication date: Available online 5 June 2018 Source:Journal of the Academy of Nutrition and Dietetics Author(s): Georgina Rubal-Peace, Caroline Sepp (Source: Journal of the Academy of Nutrition and Dietetics)
Source: Journal of the Academy of Nutrition and Dietetics - June 17, 2018 Category: Nutrition Source Type: research

Isothermal amplification using modified primers for rapid electrochemical analysis of coeliac disease associated DQB1*02 HLA allele.
Abstract DNA biosensors are attractive tools for genetic analysis as there is an increasing need for rapid and low-cost DNA analysis, primarily driven by applications in personalized pharmacogenomics, clinical diagnostics, rapid pathogen detection, food traceability and forensics. A rapid electrochemical genosensor detection methodology exploiting a combination of modified primers for solution-phase isothermal amplification, followed by rapid detection via hybridization on gold electrodes is reported. Modified reverse primers, exploiting a C18 spacer between the primer-binding site and an engineered single strande...
Source: Analytical Biochemistry - June 16, 2018 Category: Biochemistry Authors: Al-Madhagi S, Joda H, Jauset-Rubio M, Ortiz M, Katakis I, O'Sullivan CK Tags: Anal Biochem Source Type: research

Pathogenesis of Enteropathy-Associated T Cell Lymphoma
AbstractPurpose of ReviewTo provide an update on the pathogenesis of enteropathy-associated T cell lymphoma (EATL) and its relationship with refractory celiac disease (RCD), in light of current knowledge of immune, genetic, and environmental factors that promote neoplastic transformation of intraepithelial lymphocytes (IELs).Recent FindingsEATL frequently evolves from RCD type II (RCD II) but can occur “de novo” in individuals with celiac disease. Recurrent activating mutations in members of the JAK/STAT pathway have been recently described in EATL and RCD II, which suggests deregulation of cytokine signaling t...
Source: Current Hematologic Malignancy Reports - June 15, 2018 Category: Hematology Source Type: research

Low Rates of Screening for Celiac Disease Among Family Members
Given the increased morbidity and potential mortality of celiac disease, guidelines recommend screening high-risk individuals, including first-degree relatives of patients. We assessed how commonly celiac disease testing occurs in these individuals and identified factors that influence testing. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - June 15, 2018 Category: Gastroenterology Authors: Adam S. Faye, Fernanda Polubriaginof, Peter H.R. Green, David K. Vawdrey, Nicholas Tatonetti, Benjamin Lebwohl Source Type: research

Clinical intervention using Bifidobacterium strains in celiac disease children reveals novel microbial modulators of TNF- < alpha > and short-chain fatty acids
In this study, we aimed to identify correlations between fecal microbiota, serum tumor necrosis factor alpha (TNF-) and fecal short-chain fatty acids (SCFAs) in healthy children and children with CD after administration of probiotic Bifidobacterium breve BR03 and B632. (Source: Clinical Nutrition)
Source: Clinical Nutrition - June 15, 2018 Category: Nutrition Authors: Ma ša Primec, Martina Klemenak, Diana Di Gioia, Irene Aloisio, Nicole Bozzi Cionci, Andrea Quagliariello, Mario Gorenjak, Dušanka Mičetić-Turk, Tomaž Langerholc Tags: Original article Source Type: research

Low Rates of Screening for Celiac Disease Among Family  Members
Given the increased morbidity and potential mortality of celiac disease, guidelines recommend screening high-risk individuals, including first-degree relatives of patients. We assessed how commonly celiac disease testing occurs in these individuals and identified factors that influence testing. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - June 15, 2018 Category: Gastroenterology Authors: Adam S. Faye, Fernanda Polubriaginof, Peter H.R. Green, David K. Vawdrey, Nicholas Tatonetti, Benjamin Lebwohl Source Type: research

Reproductive life in women with celiac disease; a nationwide, population-based matched cohort study
This study was funded by the Health Research Fund of Central Denmark Region and The Hede Nielsens Foundation, Denmark. The authors report no conflicts of interest in this work. (Source: Human Reproduction)
Source: Human Reproduction - June 15, 2018 Category: Reproduction Medicine Source Type: research

Transition in Pediatric and Adolescent Hypogonadal Girls: Gynecological Aspects, Estrogen Replacement Therapy, and Contraception.
uul A Abstract Hypogonadism may be suspected if puberty is delayed. Pubertal delay may be caused by a normal physiological variant, by primary ovarian insufficiency (Turner syndrome), or reflect congenital hypogonadotropic hypogonadism (HH; genetic) or acquired HH (brain lesions). Any underlying chronic disease like inflammatory bowel disease, celiac disease, malnutrition (anorexia or orthorexia), or excessive physical activity may also result in functional HH. Thus, girls with delayed puberty should be evaluated for an underlying pathology before any treatment, including oral contraception, is initiated. Estrogen...
Source: Endocrine Development - June 14, 2018 Category: Endocrinology Authors: Tønnes Pedersen A, Cleemann L, Main KM, Juul A Tags: Endocr Dev Source Type: research

Prevalence of celiac disease among pediatric patients with cryptogenic cirrhosis and effect of gluten-free-diet
ConclusionThe prevalence of CD in cryptogenic cirrhosis was 13.1%. Screening for CD is recommended for cryptogenic cirrhosis. Hepatic functions improve with a GFD in CD patients with cirrhosis. (Source: Indian Journal of Gastroenterology)
Source: Indian Journal of Gastroenterology - June 13, 2018 Category: Gastroenterology Source Type: research

Borderline resectable pancreatic cancer. challenges and controversies
Pancreatic cancer (PC) is the fourth leading cause of cancer-related deaths in developed countries with an overall 5-year survival rate of 7% [1], and is expected to be the second cancer cause of death by 2030 [2]. Surgery still remains the best therapy for potentially curative purposes, but only 15-20% of the patients are candidates for resection. The resectability criteria are based on the absence of distant metastasis and the extent of vascular involvement. For a long time, tumours with no contact with major mesenteric or celiac vessels were considered resectable, and those with invasion of the arteries or mesenteric-po...
Source: Cancer Treatment Reviews - June 13, 2018 Category: Cancer & Oncology Authors: Luis Sabater, Elena Mu ñoz, Susana Roselló, Dimitri Dorcaratto, Marina Garcés-Albir, Marisol Huerta, Desamparados Roda, María Carmen Gómez-Mateo, Antonio Ferrández-Izquierdo, Antonio Darder, Andrés Cervantes Tags: Anti-Tumour Treatment Source Type: research

Capsule endoscopy for patients with coeliac disease.
Authors: Chetcuti Zammit S, Sidhu R, Sanders DS Abstract INTRODUCTION: Coeliac disease is an autoimmune mediated condition in response to gluten. A combination of innate and adaptive immune responses results in villous shortening in the small bowel which can be morphologically picked up on capsule endoscopy. Small bowel capsule endoscopy is the only imaging modality that can provide mucosal views of the whole length of the small bowel whilst histology is generally limited to the proximal small bowel. Radiological modalities are not designed to pick up changes in villous morphology. Areas covered: In this review, we...
Source: Expert Review of Gastroenterology and Hepatology - June 12, 2018 Category: Gastroenterology Tags: Expert Rev Gastroenterol Hepatol Source Type: research

Dietary Intake and Micronutrient Supplementation in Youth with Celiac Disease with and without Type 1 Diabetes.
Abstract The study purpose was to describe dietary intake and the factors influencing micronutrient supplements (MS) use in Celiac Disease (CD) ± Type 1 Diabetes (T1D). Three-day food records collected from parents of youth (3-18 years) with CD (n = 14) ± T1D (n = 10) were assessed for macro and micronutrient intake, diet quality (DQ), glycemic index (GI), glycemic load (GL), and food group intake. Focus group methodology and thematic concept analysis were conducted to determine factors influencing adolescent MS use. Mean ± ...
Source: Canadian Journal of Dietetic Practice and Research - June 12, 2018 Category: Nutrition Authors: Liu A, Marcon M, Assor E, Mahmud FH, Turner J, Mager D Tags: Can J Diet Pract Res Source Type: research