Understanding the obesity paradox in cancer: looking to body composition and tumor-specific biology to understand this complex association.
PMID: 33236039 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - November 24, 2020 Category: Nutrition Authors: Sanchez A, Furberg H Tags: Am J Clin Nutr Source Type: research

Replacing white rice bars with peanuts as snacks in the habitual diet improves metabolic syndrome risk among Chinese adults: a randomized controlled trial.
CONCLUSIONS: Including peanuts as a snack in the habitual diet in place of a refined-grain snack did not significantly change glycemic or lipid parameters, but improved overall MetS risk without promoting weight gain among Chinese adults at high risk of cardiometabolic diseases. Further larger-scale trials are needed to confirm these findings and elucidate underlying biological mechanisms.This trial was registered at clinicaltrials.gov as NCT03194152. PMID: 33236043 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - November 24, 2020 Category: Nutrition Authors: Wang D, Sun L, Liu X, Niu Z, Chen S, Tang L, Zheng H, Chen X, Li H, Lu L, Malik V, Lin X Tags: Am J Clin Nutr Source Type: research

Higher habitual flavonoid intakes are associated with a lower risk of peripheral artery disease hospitalizations.
CONCLUSIONS: Ensuring the adequate consumption of flavonoid-rich foods, particularly in subpopulations prone to the development of atherosclerosis, may be a key strategy to lower the risk of PAD. PMID: 33236045 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - November 24, 2020 Category: Nutrition Authors: Bondonno NP, Murray K, Cassidy A, Bondonno CP, Lewis JR, Croft KD, Kyrø C, Gislason G, Torp-Pedersen C, Scalbert A, Tjønneland A, Hodgson JM, Dalgaard F Tags: Am J Clin Nutr Source Type: research

The impact of malnutrition on short-term morbidity and mortality in ambulatory patients with heart failure.
Abstract BACKGROUND: Malnutrition is common in patients with chronic heart failure (CHF) and is associated with adverse outcomes, but it is uncertain how malnutrition should best be evaluated. OBJECTIVES: This prospective cohort study aims to compare the short-term prognostic value of 9 commonly used malnutrition tools in patients with CHF. METHODS: We assessed, simultaneously, 3 simple tools [Controlling Nutritional Status (CONUT) score, Geriatric Nutritional Risk Index, and Prognostic Nutritional Index], 3 multidimensional tools [Malnutrition Universal Screening Tool, Mini Nutritional Assessment-Short ...
Source: The American Journal of Clinical Nutrition - November 24, 2020 Category: Nutrition Authors: Sze S, Pellicori P, Zhang J, Weston J, Clark AL Tags: Am J Clin Nutr Source Type: research

Circulating carotenoids and breast cancer among high-risk individuals.
CONCLUSIONS: The inverse associations between circulating carotenoids and breast cancer risk appeared to be more pronounced in high-risk women, as defined by germline genetic makeup or MD. PMID: 33236056 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - November 24, 2020 Category: Nutrition Authors: Peng C, Gao C, Lu D, Rosner BA, Zeleznik O, Hankinson SE, Kraft P, Eliassen AH, Tamimi RM Tags: Am J Clin Nutr Source Type: research

The importance of food systems and the environment for nutrition.
Abstract Global and local food system transformation is necessary in order to ensure the delivery of healthy, safe, and nutritious foods in both sustainable and equitable ways. Food systems are complex entities that affect diets, human health, and a range of other outcomes including economic growth, natural resource and environmental resiliency, and sociocultural factors. However, food systems contribute to and are vulnerable to ongoing climate and environmental changes that threaten their sustainability. Although there has been increased focus on this topic in recent years, many gaps in our knowledge persist on t...
Source: The American Journal of Clinical Nutrition - November 24, 2020 Category: Nutrition Authors: Fanzo J, Bellows AL, Spiker ML, Thorne-Lyman AL, Bloem MW Tags: Am J Clin Nutr Source Type: research

Dietary taste patterns in early childhood: the Generation R Study.
CONCLUSIONS: Dietary taste patterns in this Dutch cohort were more varied and intense in taste at age 2 y than at 1 y, reaching a level similar to that previously observed in Dutch adults. Important factors related to dietary taste patterns of young children are maternal sociodemographic factors and feeding practices.This trial was registered at trialregister.nl as NL6484. PMID: 33184622 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - November 12, 2020 Category: Nutrition Authors: Nguyen AN, van Langeveld AWB, de Vries JHM, Ikram MA, de Graaf C, Mars M, Voortman T Tags: Am J Clin Nutr Source Type: research

Dietary carotenoids related to risk of incident Alzheimer dementia (AD) and brain AD neuropathology: a community-based cohort of older adults.
Abstract BACKGROUND: Studies have reported a protective relation to cognitive decline with long-term intake of total and individual dietary carotenoids. However, the underlying mechanisms have not yet been clearly established in humans. OBJECTIVES: To evaluate the prospective association between intakes of total and individual carotenoids and risk of incident Alzheimer dementia (AD) and explore the underlying neuropathological basis. METHODS: Among 927 participants from the Rush Memory and Aging Project who were free from AD at baseline and were followed up for a mean of 7 y, we estimated HRs for AD usin...
Source: The American Journal of Clinical Nutrition - November 12, 2020 Category: Nutrition Authors: Yuan C, Chen H, Wang Y, Schneider JA, Willett WC, Morris MC Tags: Am J Clin Nutr Source Type: research

Genetic, lifestyle, and health-related characteristics of adults without celiac disease who follow a gluten-free diet: a population-based study of 124,447 participants.
CONCLUSIONS: Gluten-free diet followers have a better cardiovascular risk profile than non-gluten-free diet followers but poorer self-reported health and a higher prevalence of blood and immune disorders and digestive conditions. Reasons for following a gluten-free diet warrant further investigation. PMID: 33184625 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - November 12, 2020 Category: Nutrition Authors: Littlejohns TJ, Chong AY, Allen NE, Arnold M, Bradbury KE, Mentzer AJ, Soilleux EJ, Carter JL Tags: Am J Clin Nutr Source Type: research

Energy deficit increases hepcidin and exacerbates declines in dietary iron absorption following strenuous physical activity: a randomized-controlled cross-over trial.
Abstract BACKGROUND: Strenuous physical activity promotes inflammation and depletes muscle glycogen, which may increase the iron regulatory hormone hepcidin. Hepcidin reduces dietary iron absorption and may contribute to declines in iron status frequently observed following strenuous physical activity. OBJECTIVES: To determine the effects of strenuous physical activity on hepcidin and dietary iron absorption and whether energy deficit compared with energy balance modifies those effects. METHODS: This was a randomized, cross-over, controlled-feeding trial in healthy male subjects (n = 10, mean&n...
Source: The American Journal of Clinical Nutrition - November 12, 2020 Category: Nutrition Authors: Hennigar SR, McClung JP, Hatch-McChesney A, Allen JT, Wilson MA, Carrigan CT, Murphy NE, Teien HK, Martini S, Gwin JA, Karl JP, Margolis LM, Pasiakos SM Tags: Am J Clin Nutr Source Type: research

Longitudinal associations of modifiable risk factors in the first 1000 days with weight status and metabolic risk in early adolescence.
Abstract BACKGROUND: Many studies have identified early-life risk factors for childhood overweight/obesity (OwOb), but few have evaluated how they combine to influence later cardiometabolic health. OBJECTIVES: We aimed to examine the association of risk factors in the first 1000 d with adiposity and cardiometabolic risk in early adolescence. METHODS: We studied 1038 mother-child pairs in Project Viva. We chose 6 modifiable early-life risk factors previously associated with child adiposity or metabolic health in the cohort: smoking during pregnancy (yes compared with no); gestational weight gain (excessiv...
Source: The American Journal of Clinical Nutrition - November 12, 2020 Category: Nutrition Authors: Hu J, Aris IM, Lin PD, Rifas-Shiman SL, Perng W, Woo Baidal JA, Wen D, Oken E Tags: Am J Clin Nutr Source Type: research

Vitamin E catabolism in women, as modulated by food and by fat, studied using 2 deuterium-labeled α-tocopherols in a 3-phase, nonrandomized crossover study.
Vitamin E catabolism in women, as modulated by food and by fat, studied using 2 deuterium-labeled α-tocopherols in a 3-phase, nonrandomized crossover study. Am J Clin Nutr. 2020 Nov 12;: Authors: Traber MG, Leonard SW, Ebenuwa I, Violet PC, Niyyati M, Padayatty S, Smith S, Bobe G, Levine M Abstract BACKGROUND: Human vitamin E (α-tocopherol) catabolism is a mechanism for regulating whole-body α-tocopherol. OBJECTIVES: To determine the roles of the intestine and liver on α-tocopherol catabolism as affected by fat or fasting, 2 deuterium-labeled (intravenous d6- and oral d3-)...
Source: The American Journal of Clinical Nutrition - November 12, 2020 Category: Nutrition Authors: Traber MG, Leonard SW, Ebenuwa I, Violet PC, Niyyati M, Padayatty S, Smith S, Bobe G, Levine M Tags: Am J Clin Nutr Source Type: research

The impact of diets rich in low-fat or full-fat dairy on glucose tolerance and its determinants: a randomized controlled trial.
CONCLUSIONS: Contrary to our hypothesis, neither dairy diet improved glucose tolerance in individuals with metabolic syndrome. Both dairy diets decreased insulin sensitivity through mechanisms largely unrelated to changes in key determinants of insulin sensitivity.This trial was registered at clinicaltrials.gov as NCT02663544. PMID: 33184632 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - November 12, 2020 Category: Nutrition Authors: Schmidt KA, Cromer G, Burhans MS, Kuzma JN, Hagman DK, Fernando I, Murray M, Utzschneider KM, Holte S, Kraft J, Kratz M Tags: Am J Clin Nutr Source Type: research

Folate, vitamin B-12, and cognitive function in the Boston Puerto Rican Health Study.
We examined dietary and plasma folate and vitamin B-12 status, and their interaction, in relation to cognitive function in a cohort of older Puerto Rican adults. METHODS: The design is cross-sectional, with 1408 participants from the Boston Puerto Rican Health Study (mean ± SD age: 57.1 ± 7.9 y). Cognitive function was assessed with a comprehensive test battery and a global composite score was derived. Plasma folate, vitamin B-12, and methylmalonic acid (MMA) were assessed in fasting blood samples. RESULTS: After adjusting for covariates, high plasma folate and high plasma vitami...
Source: The American Journal of Clinical Nutrition - November 12, 2020 Category: Nutrition Authors: Boumenna T, Scott TM, Lee JS, Palacios N, Tucker KL Tags: Am J Clin Nutr Source Type: research

Diagnostic performance of midupper arm circumference for detecting severe wasting among infants aged 1-6 months in Ethiopia.
CONCLUSIONS: A MUAC cutoff of ≤112 mm performed well in detecting severe wasting among infants aged 1-6 mo. Further research is needed to evaluate the performance of MUAC for detecting wasting at community level and for predicting mortality among infants aged
Source: The American Journal of Clinical Nutrition - November 12, 2020 Category: Nutrition Authors: Jima BR, Hassen HY, Getnet Y, Bahwere P, Gebreyesus SH Tags: Am J Clin Nutr Source Type: research

Vitamin D in human serum and adipose tissue after supplementation.
CONCLUSIONS: We validated a sensitive, robust, and high-throughput LC-MS/MS method to quantify vitamins D3 and D2 in serum. Serum and SUBQ adipose tissue vitamin D3 concentrations increased proportionally to dose with 3 mo of daily supplementation.These trials were registered at clinicaltrials.gov as NCT00552409 (pilot study 1) and NCT01477034 (pilot study 2). PMID: 33184642 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - November 12, 2020 Category: Nutrition Authors: Best CM, Riley DV, Laha TJ, Pflaum H, Zelnick LR, Hsu S, Thummel KE, Foster-Schubert KE, Kuzma JN, Cromer G, Larson I, Hagman DK, Heshelman K, Kratz M, de Boer IH, Hoofnagle AN Tags: Am J Clin Nutr Source Type: research

Revisiting the critical weight hypothesis for regulation of pubertal timing in boys.
Abstract BACKGROUND: Recent findings indicate that there is a body weight-sensing homeostatic regulation of body weight in postpubertal rodents and humans. It is possible that body weight sensing also might be involved in the regulation of pubertal timing. Although an early small study suggested that there is a critical body weight for pubertal timing in girls, most studies have focused on BMI and reported an inverse association between BMI and pubertal timing. OBJECTIVES: In the present longitudinal well-powered cohort study, we revisited the critical weight hypothesis and tested if prepubertal body weight i...
Source: The American Journal of Clinical Nutrition - November 12, 2020 Category: Nutrition Authors: Bygdell M, Kindblom JM, Jansson JO, Ohlsson C Tags: Am J Clin Nutr Source Type: research

Daily consumption of pro-vitamin A biofortified (yellow) cassava improves serum retinol concentrations in preschool children in Nigeria: a randomized controlled trial.
CONCLUSIONS: Daily consumption of β-carotene from biofortified cassava improved serum retinol and hemoglobin concentrations modestly in Nigerian preschool children. This study was registered with clinicaltrials.gov as NCT02627222. PMID: 33184647 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - November 12, 2020 Category: Nutrition Authors: Afolami I, Mwangi MN, Samuel F, Boy E, Ilona P, Talsma EF, Feskens E, Melse-Boonstra A Tags: Am J Clin Nutr Source Type: research

Is there a survival advantage of oral immunonutrition in head and neck cancer?
PMID: 33184649 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - November 12, 2020 Category: Nutrition Authors: Adiamah A, Lewis S Tags: Am J Clin Nutr Source Type: research

Dietary pattern trajectories across adolescence and early adulthood and their associations with childhood and parental factors.
CONCLUSIONS: Poor dietary patterns established in adolescence are likely to track into early adulthood, particularly in males. This study highlights the transition between adolescence and early adulthood as a critical period and the populations that could benefit from dietary interventions. PMID: 33181820 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - November 12, 2020 Category: Nutrition Authors: Appannah G, Murray K, Trapp G, Dymock M, Oddy WH, Ambrosini GL Tags: Am J Clin Nutr Source Type: research

Total carotenoid intake is associated with reduced loss of grip strength and gait speed over time in adults: The Framingham Offspring Study.
CONCLUSIONS: Higher antioxidant intake was associated with increase in grip strength and faster gait speed in this cohort of adults. This finding highlights the need for a randomized controlled trial of dietary antioxidants and their effect on muscle strength and physical function. PMID: 33181830 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - November 12, 2020 Category: Nutrition Authors: Sahni S, Dufour AB, Fielding RA, Newman AB, Kiel DP, Hannan MT, Jacques PF Tags: Am J Clin Nutr Source Type: research

Inflammation correction in micronutrient deficiency with censored inflammatory biomarkers.
Abstract BACKGROUND: Biomarkers of micronutrient status vary with inflammation, and can be corrected by a regression-based approach [Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA)] using measured concentrations of inflammation biomarkers, e.g., C-reactive protein (CRP) and/or α1-acid-glycoprotein (AGP). However, this is confounded when inflammation is measured with multiple assays with variable limits of detection (LOD) and lower limits of quantification (LLOQ). OBJECTIVES: We aimed to develop a probability approach for the estimation of prevalence of micronutrient de...
Source: The American Journal of Clinical Nutrition - November 12, 2020 Category: Nutrition Authors: Ghosh S, Kurpad AV, Sachdev HS, Thomas T Tags: Am J Clin Nutr Source Type: research

Corrigendum for Itariu et al. (Long-chain n-3 PUFAs reduce adipose tissue and systemic inflammation in severely obese nondiabetic patients: a randomized controlled trial). Am J Clin Nutr 2012;96(5):1137-49.
Authors: PMID: 33175970 [PubMed - in process] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - November 11, 2020 Category: Nutrition Tags: Am J Clin Nutr Source Type: research

Corrigendum for Wise LA, Wesselink AK, Mikkelsen EM, Cueto H, Hahn KA, Rothman KJ, Tucker KL, S ørensen HT, Hatch EE. Dairy intake and fecundability in 2 preconception cohort studies. Am J Clin Nutr. 2017;105(1):100-110.
Corrigendum for Wise LA, Wesselink AK, Mikkelsen EM, Cueto H, Hahn KA, Rothman KJ, Tucker KL, Sørensen HT, Hatch EE. Dairy intake and fecundability in 2 preconception cohort studies. Am J Clin Nutr. 2017;105(1):100-110. Am J Clin Nutr. 2020 Nov 11;112(5):1404 Authors: PMID: 33175971 [PubMed - in process] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - November 11, 2020 Category: Nutrition Tags: Am J Clin Nutr Source Type: research

An Expression of Concern from the AJCN Editorial Office about: Magnesium supplementation affects metabolic status and pregnancy outcomes in gestational diabetes: a randomized, double-blind, placebo-controlled trial.
PMID: 33094799 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - October 23, 2020 Category: Nutrition Authors: Asemi Z, Karamali M, Jamilian M, Foroozanfard F, Bahmani F, Heidarzadeh Z, Benisi-Kohansal S, Surkan PJ, Esmaillzadeh A Tags: Am J Clin Nutr Source Type: research

Replacing the consumption of red meat with other major dietary protein sources and risk of type 2 diabetes mellitus: a prospective cohort study.
CONCLUSIONS: Replacing red meat consumption with other protein sources was associated with a lower risk of T2DM. PMID: 33094800 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - October 23, 2020 Category: Nutrition Authors: Würtz AML, Jakobsen MU, Bertoia ML, Hou T, Schmidt EB, Willett WC, Overvad K, Sun Q, Manson JE, Hu FB, Rimm EB Tags: Am J Clin Nutr Source Type: research

Higher eating frequency is associated with lower adiposity and robust circadian rhythms: a cross-sectional study.
CONCLUSIONS: The daily pattern of energy intake is associated with adiposity and robust circadian rhythms. Our results shed light on the relevance of eating frequency as a potential zeitgeber for the circadian system. Although more evidence is needed, eating frequency could be considered for future chrono-nutritional recommendations for the prevention of circadian misalignment and obesity. PMID: 33094802 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - October 23, 2020 Category: Nutrition Authors: Zerón-Rugerio MF, Díez-Noguera A, Izquierdo-Pulido M, Cambras T Tags: Am J Clin Nutr Source Type: research

Pediatric undernutrition defined by body composition-are we there yet?
PMID: 33094806 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - October 23, 2020 Category: Nutrition Authors: Hron BM, Duggan CP Tags: Am J Clin Nutr Source Type: research

An Expression of Concern from the AJCN Editorial Office about: Effects of vitamin D supplementation on glucose metabolism, lipid concentrations, inflammation, and oxidative stress in gestational diabetes: a double-blind randomized controlled clinical trial.
PMID: 33094821 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - October 23, 2020 Category: Nutrition Authors: Asemi Z, Hashemi T, Karamali M, Samimi M, Esmaillzadeh A Tags: Am J Clin Nutr Source Type: research

Adverse effects on cognition caused by combined low vitamin B-12 and high folate status-we must do better than a definite maybe!
PMID: 33094822 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - October 23, 2020 Category: Nutrition Authors: Molloy AM Tags: Am J Clin Nutr Source Type: research

Hidden hunger: food insecurity in the age of coronavirus.
PMID: 33095254 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - October 23, 2020 Category: Nutrition Authors: Neff LM Tags: Am J Clin Nutr Source Type: research

Association between diet and periodontitis: a cross-sectional study of 10,000 NHANES participants.
CONCLUSIONS: Most dietary patterns identified were not associated with periodontitis extent. One pattern, however, rich in salad, fruit, and vegetables and with plain water or tea to drink, was associated with lower CAL extent. Treelet transformation may be a useful approach for calculating dietary patterns in nutrition research. PMID: 33096553 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - October 23, 2020 Category: Nutrition Authors: Wright DM, McKenna G, Nugent A, Winning L, Linden GJ, Woodside JV Tags: Am J Clin Nutr Source Type: research

Associations of human milk oligosaccharides and bioactive proteins with infant growth and development among Malawian mother-infant dyads.
We examined associations of the relative abundances of HMOs and concentrations of bioactive proteins with infant growth from 6 to 12 mo [change in length-for-age (ΔLAZ), weight-for-age, weight-for-length, and head circumference z-scores] as well as ability to stand or walk alone at 12 mo, and motor and language skills, socioemotional development, executive function, and working memory at 18 mo. Analyses were adjusted for covariates and multiple hypothesis testing. RESULTS: Among all participants, there were inverse associations of IgA and lactoferrin concentrations with motor skills (P = 0.018 and P =&...
Source: The American Journal of Clinical Nutrition - October 23, 2020 Category: Nutrition Authors: Jorgensen JM, Young R, Ashorn P, Ashorn U, Chaima D, Davis JCC, Goonatilleke E, Kumwenda C, Lebrilla CB, Maleta K, Prado EL, Sadalaki J, Totten SM, Wu LD, Zivkovic AM, Dewey KG Tags: Am J Clin Nutr Source Type: research

Selenium, antioxidants, cardiovascular disease, and all-cause mortality: a systematic review and meta-analysis of randomized controlled trials.
CONCLUSION: The addition of selenium should be considered for supplements containing antioxidant mixtures if they are to be associated with CVD and all-cause mortality risk reduction. This trial was registered at https://www.crd.york.ac.uk/PROSPERO/ as CRD42019138268. PMID: 33053149 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - October 14, 2020 Category: Nutrition Authors: Jenkins DJA, Kitts D, Giovannucci EL, Sahye-Pudaruth S, Paquette M, Blanco Mejia S, Patel D, Kavanagh M, Tsirakis T, Kendall CWC, Pichika SC, Sievenpiper JL Tags: Am J Clin Nutr Source Type: research

Associations of maternal fructose and sugar-sweetened beverage and juice intake during lactation with infant neurodevelopmental outcomes at 24 months.
Abstract BACKGROUND: Our prior studies revealed that infant somatic growth is influenced by fructose in breast milk, and fructose in breast milk is increased in response to maternal sugar-sweetened beverage (SSB) intake in lactation. It is unknown whether infant neurodevelopmental outcomes are also influenced by maternal SSBs in lactation. OBJECTIVES: To determine whether infant cognitive development at 24 postnatal months was influenced by maternal fructose consumption during lactation, and whether this relation persisted after accounting for maternal SSB and juice (SSB + J) intake. METHODS: H...
Source: The American Journal of Clinical Nutrition - October 6, 2020 Category: Nutrition Authors: Berger PK, Plows JF, Jones RB, Alderete TL, Rios C, Pickering TA, Fields DA, Bode L, Peterson BS, Goran MI Tags: Am J Clin Nutr Source Type: research

Vitamin D status in infancy and cardiometabolic health in adolescence.
CONCLUSIONS: Serum 25(OH)D at age 1 y is inversely associated with childhood BMIZ, percentage body fat at age 16/17 y, and a MetS score at age 16/17 y. Intervention studies are warranted to examine the effects of vitamin D supplementation in early life on long-term cardiometabolic outcomes. PMID: 33021621 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - October 6, 2020 Category: Nutrition Authors: Garfein J, Flannagan KS, Gahagan S, Burrows R, Lozoff B, Villamor E Tags: Am J Clin Nutr Source Type: research

Association between ultraprocessed food intake and cardiovascular health in US adults: a cross-sectional analysis of the NHANES 2011-2016.
Abstract BACKGROUND: Higher intake of ultraprocessed foods (UPFs) might be associated with increased risk of cardiovascular disease. OBJECTIVES: Our objective was to examine the association between usual percentage of calories (%kcal) from UPFs and the American Heart Association's "Life's Simple 7" cardiovascular health (CVH) metrics in US adults. METHODS: We analyzed data from 11,246 adults aged ≥20 y from the NHANES 2011-2016 (a cross-sectional, nationally representative survey). UPF designation was assigned on the basis of the NOVA classification system, according to the extent and p...
Source: The American Journal of Clinical Nutrition - October 6, 2020 Category: Nutrition Authors: Zhang Z, Jackson SL, Martinez E, Gillespie C, Yang Q Tags: Am J Clin Nutr Source Type: research

Assessing vitamin B-12 absorption and bioavailability: read the label.
PMID: 33021625 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - October 6, 2020 Category: Nutrition Authors: Miller JW, Green R Tags: Am J Clin Nutr Source Type: research

Cost-effectiveness of teduglutide in pediatric patients with short bowel syndrome: Markov modeling using traditional cost-effectiveness criteria.
CONCLUSIONS: At its current price, teduglutide does not provide a cost-effective addition to transplantation in the treatment of pediatric short bowel syndrome. Further work should look to identify cost-reducing strategies, including alternative dosing regimens. PMID: 33021637 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - October 6, 2020 Category: Nutrition Authors: Raghu VK, Rudolph JA, Smith KJ Tags: Am J Clin Nutr Source Type: research

Very low ileal nitrogen and amino acid digestibility of zein compared to whey protein isolate in healthy volunteers.
CONCLUSIONS: Our findings provide data on ileal digestibility of WPI and zein AAs in healthy humans and, in contrast to WPI, zein is poorly digestible. This study was registered at clinicaltrials.gov as NCT03279211. PMID: 33021640 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - October 6, 2020 Category: Nutrition Authors: Calvez J, Benoit S, Piedcoq J, Khodorova N, Azzout-Marniche D, Tomé D, Benamouzig R, Airinei G, Gaudichon C Tags: Am J Clin Nutr Source Type: research

Blood polyphenol concentrations and differentiated thyroid carcinoma in women from the European Prospective Investigation into Cancer and Nutrition (EPIC) study.
CONCLUSIONS: Blood polyphenol concentrations were mostly not associated with differentiated TC risk in women, although our study raises the possibility that high blood concentrations of caffeic, 3,4-dihydroxyphenylpropionic, and ferulic acids may be related to a lower papillary TC risk. PMID: 33021645 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - October 6, 2020 Category: Nutrition Authors: Zamora-Ros R, Lujan-Barroso L, Achaintre D, Franceschi S, Kyrø C, Overvad K, Tjønneland A, Truong T, Lecuyer L, Boutron-Ruault MC, Katzke V, Johnson TS, Schulze MB, Trichopoulou A, Peppa E, La Vechia C, Masala G, Pala V, Panico S, Tumino R, Ricceri F, S Tags: Am J Clin Nutr Source Type: research

Fruit and vegetable intake and risk of frailty in women 60 years old or older.
Abstract BACKGROUND: Prior research has suggested that the antioxidative and anti-inflammatory potential of fruits and vegetables may ameliorate aging-related frailty. OBJECTIVE: We sought to prospectively examine the association between fruit and vegetable intake and incident frailty in older women. DESIGN: We followed 78,366 nonfrail women aged ≥60 y from the Nurses' Health Study from 1990 to 2014. In this analysis, the primary exposure was the intake of total fruits and vegetables, assessed with an FFQ administered 6 times during follow-up. Frailty was defined as having ≥3 of the following 5 cri...
Source: The American Journal of Clinical Nutrition - October 6, 2020 Category: Nutrition Authors: Fung TT, Struijk EA, Rodriguez-Artalejo F, Willett WC, Lopez-Garcia E Tags: Am J Clin Nutr Source Type: research

Yogurt consumption and colorectal cancer incidence and mortality in the Nurses' Health Study and the Health Professionals Follow-Up Study.
Abstract BACKGROUND: Yogurt is a commonly consumed fermented food. Regular yogurt consumption may contribute to a favorable gut microbiome and gut health, but few epidemiologic studies have considered the relation between regular yogurt consumption and the incidence of and mortality from colorectal cancer. OBJECTIVES: We used data from 2 large, prospective cohort studies, the Nurses' Health Study and the Health Professionals Follow-Up Study, to examine the role of yogurt consumption on colorectal cancer incidence and mortality. METHODS: During 32 years of follow-up in 83,054 women (mean age at baseline, ...
Source: The American Journal of Clinical Nutrition - October 6, 2020 Category: Nutrition Authors: Michels KB, Willett WC, Vaidya R, Zhang X, Giovannucci E Tags: Am J Clin Nutr Source Type: research

Efficacy of different dietary patterns on lowering of blood pressure level: an umbrella review.
CONCLUSION: Adherence to the DASH, Nordic, and portfolio diets effectively reduced BP. Low-salt diets significantly decreased BP levels in normotensive Afro-Caribbean people and in hypertensive patients of all ethnic origins. This review was registered at PROSPERO as CRD42018104733. PMID: 33022695 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - October 6, 2020 Category: Nutrition Authors: Sukhato K, Akksilp K, Dellow A, Vathesatogkit P, Anothaisintawee T Tags: Am J Clin Nutr Source Type: research

The potential of novel plant protein foods to improve dietary patterns and markers of cardiovascular health.
PMID: 33022696 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - October 6, 2020 Category: Nutrition Authors: Anderson CAM, Bradley R Tags: Am J Clin Nutr Source Type: research

A heart-healthy preconception diet for the prevention of hypertensive disorders of pregnancy: what do we know and where to next?
PMID: 33022697 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - October 6, 2020 Category: Nutrition Authors: Schoenaker DAJM, Alwan NA Tags: Am J Clin Nutr Source Type: research

Late eating is associated with cardiometabolic risk traits, obesogenic behaviors, and impaired weight loss.
Garaulet M Abstract BACKGROUND: There is a paucity of evidence regarding the role of food timing on cardiometabolic health and weight loss in adults. OBJECTIVES: To determine whether late eating is cross-sectionally associated with obesity and cardiometabolic risk factors at baseline; and whether late eating is associated with weight loss rate and success following a weight loss intervention protocol. Also, to identify obesogenic behaviors and weight loss barriers associated with late eating. METHODS: Participants were recruited from a weight-loss program in Spain. Upon recruitment, the midpoint of meal...
Source: The American Journal of Clinical Nutrition - October 6, 2020 Category: Nutrition Authors: Dashti HS, Gómez-Abellán P, Qian J, Esteban A, Morales E, Scheer FAJL, Garaulet M Tags: Am J Clin Nutr Source Type: research

Red blood cell membrane trans fatty acid levels and risk of non-Hodgkin lymphoma: a prospective nested case-control study.
CONCLUSIONS: Our findings extended evidence for TFA intake and DLBCL risk but not for other NHL subtypes. Reduced TFA consumption through dietary choices or health policy measures may support prevention of DLBCL, an aggressive NHL subtype. PMID: 33022699 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - October 6, 2020 Category: Nutrition Authors: Ardisson Korat AV, Chiu YH, Bertrand KA, Zhang S, Epstein MM, Rosner BA, Chiuve S, Campos H, Giovannucci EL, Chavarro JE, Birmann BM Tags: Am J Clin Nutr Source Type: research

Associations of sodium and potassium consumption with the gut microbiota and host metabolites in a population-based study in Chinese adults.
We examined the associations of energy-adjusted dietary sodium (milligrams/kilocalorie), potassium, and sodium-to-potassium (Na/K) ratio with the microbiota and plasma metabolome in a well-characterized Chinese cohort with habitual excessive sodium and deficient potassium consumption. METHODS: We estimated dietary intakes from 3 consecutive validated 24-h recalls and household inventories. In 2833 adults (18-80 y old, 51.2% females), we analyzed microbial (genus-level 16S ribosomal RNA) between-person diversity, using distance-based redundancy analysis (dbRDA), and within-person diversity and taxa abundance using line...
Source: The American Journal of Clinical Nutrition - October 6, 2020 Category: Nutrition Authors: Wang Y, Wang H, Howard AG, Tsilimigras MCB, Avery CL, Meyer KA, Sha W, Sun S, Zhang J, Su C, Wang Z, Zhang B, Fodor AA, Gordon-Larsen P Tags: Am J Clin Nutr Source Type: research

Prospective study of a diabetes risk reduction diet and the risk of breast cancer.
Abstract BACKGROUND: Hyperinsulinemia and higher insulin-like growth factors may increase breast cancer risk. We evaluated a diabetes risk reduction diet (DRRD) and breast cancer risk. OBJECTIVES: We prospectively evaluated the association between adherence to a DRRD and the incidence of breast cancer. METHODS: We followed 88,739 women from the Nurses' Health Study (NHS; 1980-2016) and 93,915 women from the NHSII (1991-2017). Incident breast cancer cases (n = 11,943) were confirmed with medical records, and subtypes were determined by tissue microarray data and pathology reports. Information on...
Source: The American Journal of Clinical Nutrition - October 6, 2020 Category: Nutrition Authors: Kang JH, Peng C, Rhee JJ, Farvid MS, Willett WC, Hu FB, Rosner BA, Tamimi R, Eliassen AH Tags: Am J Clin Nutr Source Type: research