Prevalence and correlates of vitamin D deficiency in a tropical setting: results from a nationally representative survey.
We examined the prevalence and distribution of VDD by individual and environmental characteristics in a nationally representative sample of Colombian children, pregnant women, and adult nonpregnant women. METHODS: Using the 2015 Colombian National Nutrition Survey, we defined VDD and low vitamin D (LVD) as serum 25-hydroxyvitamin D [25(OH)D]
Source: The American Journal of Clinical Nutrition - July 30, 2020 Category: Nutrition Authors: Beer RJ, Herrán OF, Villamor E Tags: Am J Clin Nutr Source Type: research

Two weeks of early time-restricted feeding (eTRF) improves skeletal muscle insulin and anabolic sensitivity in healthy men.
CONCLUSIONS: Under free-living conditions, eTRF improves whole-body insulin sensitivity and increases skeletal muscle glucose and BCAA uptake. The metabolic benefits of eTRF are independent of its effects on weight loss and represent chronic adaptations rather than the effect of the last bout of overnight fast. This trial was registered at clinicaltrials.gov as NCT03969745. PMID: 32729615 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - July 30, 2020 Category: Nutrition Authors: Jones R, Pabla P, Mallinson J, Nixon A, Taylor T, Bennett A, Tsintzas K Tags: Am J Clin Nutr Source Type: research

Dietary nicotine intake and risk of Parkinson disease: a prospective study.
CONCLUSIONS: Women with greater dietary nicotine intake had a lower risk of PD than those with lower intake. PMID: 32725131 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - July 29, 2020 Category: Nutrition Authors: Ma C, Molsberry S, Li Y, Schwarzschild M, Ascherio A, Gao X Tags: Am J Clin Nutr Source Type: research

Combined infant and young child feeding with small-quantity lipid-based nutrient supplementation is associated with a reduction in anemia but no changes in anthropometric status of young children from Katanga Province of the Democratic Republic of Congo: a quasi-experimental effectiveness study.
Abstract BACKGROUND: Small-quantity lipid-based nutrient supplements (SQ-LNS) are efficacious in controlled settings; data are scarce on the effectiveness utilizing health care delivery platforms. OBJECTIVE: We evaluated the impact of an infant young child feeding (IYCF)-SQ-LNS intervention on anemia and growth in children aged 6-18 mo in the Democratic Republic of Congo following a quasi-experimental effectiveness design. METHODS: An intervention health zone (HZ) received enhanced IYCF including improved counseling on IYCF during pregnancy until 12 mo after birth and daily use of SQ-LNS for infants 6-12...
Source: The American Journal of Clinical Nutrition - July 25, 2020 Category: Nutrition Authors: Addo OY, Locks LM, Jefferds ME, Nanama S, Albert B, Sandalinas F, Nanema A, Whitehead RD, Mei Z, Clayton HB, Garg A, Kupka R, Tripp K Tags: Am J Clin Nutr Source Type: research

Impact of habituated dietary protein intake on fasting and postprandial whole-body protein turnover and splanchnic amino acid metabolism in elderly men: a randomized, controlled, crossover trial.
all G, Holm L Abstract BACKGROUND: Efficacy of protein absorption and subsequent amino acid utilization may be reduced in the elderly. Higher protein intakes have been suggested to counteract this. OBJECTIVES: We aimed to elucidate how habituated amounts of protein intake affect the fasted state of, and the stimulatory effect of a protein-rich meal on, protein absorption, whole-body protein turnover, and splanchnic amino acid metabolism. METHODS: Twelve men (65-70 y) were included in a double-blinded crossover intervention study, consisting of a 20-d habituation period to a protein intake at the RDA or a...
Source: The American Journal of Clinical Nutrition - July 25, 2020 Category: Nutrition Authors: Højfeldt G, Bülow J, Agergaard J, Asmar A, Schjerling P, Simonsen L, Bülow J, van Hall G, Holm L Tags: Am J Clin Nutr Source Type: research

A call for action: standard of care guidelines to assess vitamin D status are needed for patients with hip fracture.
PMID: 32710753 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - July 25, 2020 Category: Nutrition Authors: Holick MF Tags: Am J Clin Nutr Source Type: research

The effect of routine probiotics supplementation on preterm newborn health: a regression discontinuity analysis.
CONCLUSIONS: Routine treatment of moderately preterm newborns with probiotics is unlikely to improve anthropometric outcomes. Complier-level analysis suggested that this finding was not simply driven by a lack of physician compliance with hospital guidelines but by an overall absence of large health effects from the treatment itself. Moreover, overall sepsis risk was low and did not change significantly as a result of probiotics supplementation. The findings of this study therefore do not support the routine use of probiotics for improving growth or preventing late-onset sepsis in moderately preterm neonates. PMID: 32...
Source: The American Journal of Clinical Nutrition - July 25, 2020 Category: Nutrition Authors: Bommer C, Horn S, Vollmer S Tags: Am J Clin Nutr Source Type: research

How countries can reduce child stunting at scale: lessons from exemplar countries.
CONCLUSIONS: Our results show that child stunting reduction is possible even in diverse and challenging contexts. We propose that our framework of organizing nutrition interventions as direct/indirect and inside/outside the health sector should be considered when mapping causal pathways of child stunting and planning interventions and strategies to accelerate stunting reduction to achieve the 2030 Sustainable Development Goals. PMID: 32692800 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - July 21, 2020 Category: Nutrition Authors: Bhutta ZA, Akseer N, Keats EC, Vaivada T, Baker S, Horton SE, Katz J, Menon P, Piwoz E, Shekar M, Victora C, Black R Tags: Am J Clin Nutr Source Type: research

Dodging physical activity and healthy diet: can resveratrol take the edge off the consequences of your lifestyle?
PMID: 32692802 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - July 21, 2020 Category: Nutrition Authors: Gliemann L Tags: Am J Clin Nutr Source Type: research

Anemia and water, sanitation, and hygiene (WASH)-is there really a link?
PMID: 32692804 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - July 21, 2020 Category: Nutrition Authors: Baldi AJ, Clucas D, Pasricha SR Tags: Am J Clin Nutr Source Type: research

Effectiveness of a normative nutrition intervention in Chilean pregnant women on maternal and neonatal outcomes: the CHiMINCs study.
This study was a cluster-randomized controlled trial of 12 primary health care centers (PHCCs) from Santiago, Chile. PHCCs were randomly allocated to either nutritional intervention [intervention group (IG), n = 5] or routine care [control group (CG), n = 7]. A total of 4631 pregnant women were recruited (IG, n = 2565; and CG, n = 2066). Primary outcomes were adequate GWG and glycemic control in mothers and birth weight, birth length, macrosomia, and large for gestational age in neonates. The intervention consisted of 4 key actions: training of health care professionals on nutritiona...
Source: The American Journal of Clinical Nutrition - July 21, 2020 Category: Nutrition Authors: Garmendia ML, Corvalan C, Araya M, Casanello P, Kusanovic JP, Uauy R Tags: Am J Clin Nutr Source Type: research

Negative predictive value of the repeated absence of gluten immunogenic peptides in the urine of treated celiac patients in predicting mucosal healing: new proposals for follow-up in celiac disease.
CONCLUSIONS: Determining GIP concentrations in several urine samples may be an especially convenient approach to assess recent gluten exposure in celiac patients and appears to accurately predict the absence of histological lesions. The introduction of GIP testing as an assessment technique for GFD adherence may help in ascertaining dietary compliance and to target the most suitable intervention during follow-up. PMID: 32692806 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - July 21, 2020 Category: Nutrition Authors: Ruiz-Carnicer Á, Garzón-Benavides M, Fombuena B, Segura V, García-Fernández F, Sobrino-Rodríguez S, Gómez-Izquierdo L, Montes-Cano MA, Rodríguez-Herrera A, Millán R, Rico MC, González-Naranjo C, Bozada-García JM, Díaz J, Coronel-Rodríguez C, E Tags: Am J Clin Nutr Source Type: research

The genetic architecture of the association between eating behaviors and obesity: combining genetic twin modeling and polygenic risk scores.
CONCLUSIONS: Eating behavior patterns share a common genetic liability with obesity measures and are moderately heritable. Genetic susceptibility to obesity can be partly mediated by an eating pattern characterized by frequent snacking. Obesity prevention efforts might therefore benefit from focusing on eating behavior change, particularly in genetically susceptible individuals. PMID: 32685959 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - July 20, 2020 Category: Nutrition Authors: Masip G, Silventoinen K, Keski-Rahkonen A, Palviainen T, Sipilä PN, Kaprio J, Bogl LH Tags: Am J Clin Nutr Source Type: research

Strengthening federal nutrition research: request for stakeholder input.
PMID: 32687142 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - July 20, 2020 Category: Nutrition Authors: Mattes RD, Ohlhorst SD Tags: Am J Clin Nutr Source Type: research

Strengthening national nutrition research: rationale and options for a new coordinated federal research effort and authority.
CONCLUSIONS: The need and opportunities for strengthened federal nutrition research are clear, with specific identified options to help create the new leadership, strategic planning, coordination, and investment the nation requires to address the multiple nutrition-related challenges and grasp the opportunities before us. PMID: 32687145 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - July 20, 2020 Category: Nutrition Authors: Fleischhacker SE, Woteki CE, Coates PM, Hubbard VS, Flaherty GE, Glickman DR, Harkin TR, Kessler D, Li WW, Loscalzo J, Parekh A, Rowe S, Stover PJ, Tagtow A, Yun AJ, Mozaffarian D Tags: Am J Clin Nutr Source Type: research

Distinct phenotypic characteristics of normal-weight adults at risk of developing cardiovascular and metabolic diseases.
CONCLUSIONS: Cardiometabolic disease risk related to body shape in people who are normal weight according to BMI is characterized by a distinct phenotype that includes potentially modifiable behavioral health risk factors. PMID: 32687153 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - July 20, 2020 Category: Nutrition Authors: Stanley A, Schuna J, Yang S, Kennedy S, Heo M, Wong M, Shepherd J, Heymsfield SB Tags: Am J Clin Nutr Source Type: research

Associations between age-related changes in bone microstructure and strength and dietary acid load in a cohort of community-dwelling, healthy men and postmenopausal women.
Abstract BACKGROUND: The importance of dietary acid load (DAL) in the pathogenesis of osteoporosis is still debated. Age-related changes in bone microstructure and strength in relation to DAL remain largely unexplored. OBJECTIVES: We investigated the associations between changes in areal and volumetric bone mineral density (BMD), bone microstructure and strength, fracture risk, and DAL in a prospective cohort of 65-y-old healthy men and postmenopausal women. METHODS: Potential renal acid load (PRAL; mEq/d) was calculated as a DAL proxy to characterize participants' diet as alkaline (Alk-D; PRAL 5). We me...
Source: The American Journal of Clinical Nutrition - July 17, 2020 Category: Nutrition Authors: Papageorgiou M, Merminod F, Chevalley T, van Rietbergen B, Ferrari S, Rizzoli R, Biver E Tags: Am J Clin Nutr Source Type: research

The effect of iron dosing schedules on plasma hepcidin and iron absorption in Kenyan infants.
CONCLUSIONS: In Kenyan infants given 12 mg oral iron, morning and afternoon doses are comparably absorbed, dosing on consecutive days increases PHep and modestly decreases iron absorption compared with alternate day dosing, and dosing on alternate days or every third day does not increase PHep or decrease absorption. This trial was registered at clinicaltrials.gov as NCT02989311 and NCT03617575. PMID: 32678434 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - July 17, 2020 Category: Nutrition Authors: Uyoga MA, Mikulic N, Paganini D, Mwasi E, Stoffel NU, Zeder C, Karanja S, Zimmermann MB Tags: Am J Clin Nutr Source Type: research

Anthropometric data quality assessment in multisurvey studies of child growth.
Abstract BACKGROUND: Population-based surveys collect crucial data on anthropometric measures to track trends in stunting [height-for-age z score (HAZ)
Source: The American Journal of Clinical Nutrition - July 16, 2020 Category: Nutrition Authors: Perumal N, Namaste S, Qamar H, Aimone A, Bassani DG, Roth DE Tags: Am J Clin Nutr Source Type: research

Drivers of stunting reduction in the Kyrgyz Republic: A country case study.
CONCLUSIONS: Improvements in stunting were achieved amidst political and economic changes. Multilevel enablers, including poverty reduction, improved food security, and introduction of land and health reforms have contributed to improvements in health, nutrition, and stunting among children in the Kyrgyz Republic. PMID: 32672334 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - July 16, 2020 Category: Nutrition Authors: Wigle JM, Akseer N, Mogilevskii R, Brar S, Conway K, Enikeeva Z, Iamshchikova M, Islam M, Kirbasheva D, Rappaport AI, Tasic H, Vaivada T, Bhutta ZA Tags: Am J Clin Nutr Source Type: research

Associations of childhood BMI and change in BMI from childhood to adulthood with risks of hypertensive disorders in pregnancy.
CONCLUSIONS: Above-average childhood BMI values and development of overweight from childhood to adulthood were associated with increased risks of gestational hypertension and pre-eclampsia, whereas normalizing BMI from childhood to conception attenuated the risks. Thus, interventions aiming at normalizing BMI in girls with high values may be warranted to help prevent these obstetric diseases. PMID: 32672337 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - July 16, 2020 Category: Nutrition Authors: Pedersen DC, Bjerregaard LG, Nohr EA, Rasmussen KM, Baker JL Tags: Am J Clin Nutr Source Type: research

Acute glycemic and insulinemic effects of low-energy sweeteners: a systematic review and meta-analysis of randomized controlled trials.
CONCLUSIONS: Ingestion of LES, administered alone or in combination with a nutrient-containing preload, has no acute effects on the mean change in postprandial glycemic or insulinemic responses compared with a control intervention. Apart from a small beneficial effect on PPG (-0.3 mmol/L) in studies enrolling patients with type 2 diabetes, the effects did not differ by type or dose of LES, or fasting glucose or insulin levels. This review and meta-analysis was registered at PROSPERO as CRD42018099608. PMID: 32672338 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - July 16, 2020 Category: Nutrition Authors: Greyling A, Appleton KM, Raben A, Mela DJ Tags: Am J Clin Nutr Source Type: research

Maternal dietary diversity and dietary quality scores in relation to adverse birth outcomes in Tanzanian women.
CONCLUSIONS: PDQS was inversely associated with PTB, LBW, and fetal loss, and DDS was inversely associated with SGA. These findings suggest that in addition to dietary diversity, diet quality should be considered as important in understanding dietary risk factors for poor birth outcomes.This trial was registered at clinicaltrials.gov as NCT00197548. PMID: 32651998 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - July 11, 2020 Category: Nutrition Authors: Madzorera I, Isanaka S, Wang M, Msamanga GI, Urassa W, Hertzmark E, Duggan C, Fawzi WW Tags: Am J Clin Nutr Source Type: research

Infants with big appetites: The role of a nonfood environment on infant appetitive traits linked to obesity.
CONCLUSIONS: Our work contributes to the mechanistic understanding of the ontogeny of obesity development early in life among individuals who are born with appetitive drive for overconsumption. During early infancy, the nonfood environment may protect against this drive and prevent obesity development. PMID: 32652028 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - July 11, 2020 Category: Nutrition Authors: Kong KL, Anzman-Frasca S, Epstein LH, Eiden RD, Paluch RA Tags: Am J Clin Nutr Source Type: research

Understanding multifactorial drivers of child stunting reduction in Exemplar countries: a mixed-methods approach.
CONCLUSIONS: Exemplars research uses a mixed-methods framework for studying positive outliers that can be applied across diverse health and development outcomes. PMID: 32649742 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - July 10, 2020 Category: Nutrition Authors: Akseer N, Vaivada T, Rothschild O, Ho K, Bhutta ZA Tags: Am J Clin Nutr Source Type: research

Micronutrient supplementation of lactating Guatemalan women acutely increases infants' intake of riboflavin, thiamin, pyridoxal, and cobalamin, but not niacin, in a randomized crossover trial.
Abstract BACKGROUND: Maternal supplementation during lactation could increase milk B-vitamin concentrations, but little is known about the kinetics of milk vitamin responses. OBJECTIVES: We compared acute effects of maternal lipid-based nutrient supplement (LNS) consumption (n = 22 nutrients, 175%-212% of the RDA intake for the nutrients examined), as a single dose or at spaced intervals during 8 h, on milk concentrations and infant intake from milk of B-vitamins. METHODS: This randomized crossover trial in Quetzaltenango, Guatemala included 26 mother-infant dyads 4-6 mo postpartum who were ran...
Source: The American Journal of Clinical Nutrition - July 10, 2020 Category: Nutrition Authors: Donohue JA, Solomons NW, Hampel D, Shahab-Ferdows S, Orozco MN, Allen LH Tags: Am J Clin Nutr Source Type: research

Best (but oft-forgotten) practices: sample size and power calculation for a dietary intervention trial with episodically consumed foods.
Abstract Dietary interventions often target foods that are underconsumed relative to dietary guidelines, such as vegetables, fruits, and whole grains. Because these foods are only consumed episodically for some participants, data from such a study often contains a disproportionally large number of zeros due to study participants who do not consume any of the target foods on the days that dietary intake is assessed, thus generating semicontinuous data. These zeros need to be properly accounted for when calculating sample sizes to ensure that the study is adequately powered to detect a meaningful intervention effect...
Source: The American Journal of Clinical Nutrition - July 9, 2020 Category: Nutrition Authors: Zhang W, Liu A, Zhang Z, Nansel T, Halabi S Tags: Am J Clin Nutr Source Type: research

Sugar-sweetened beverage consumption and risk of hyperuricemia: a longitudinal analysis of the Health Workers Cohort Study participants in Mexico.
;nchez AD, Velázquez-Cruz R, Salmerón J Abstract BACKGROUND: The elevated consumption of sugar-sweetened beverages (SSBs) in Mexico is an important public health concern. However, the association between SSB consumption and hyperuricemia has been scarcely studied and not well documented. OBJECTIVES: To prospectively evaluate the association between SSB consumption and risk of hyperuricemia in Mexican adults. METHODS: A longitudinal analysis was conducted using data from the Health Workers Cohort Study. Participants were followed from 2004 to 2018, with measurements every 6 y. The analysis s...
Source: The American Journal of Clinical Nutrition - July 9, 2020 Category: Nutrition Authors: Meneses-León J, León-Maldonado L, Macías N, Torres-Ibarra L, Hernández-López R, Rivera-Paredez B, Flores M, Flores YN, Barrientos-Gutiérrez T, Quezada-Sánchez AD, Velázquez-Cruz R, Salmerón J Tags: Am J Clin Nutr Source Type: research

Contrasting effects of viscous and particulate fibers on colonic fermentation in vitro and in vivo, and their impact on intestinal water studied by MRI in a randomized trial.
Abstract BACKGROUND: Wheat bran, nopal, and psyllium are examples of particulate, viscous and particulate, and viscous fibers, respectively, with laxative properties yet contrasting fermentability. OBJECTIVES: We assessed the fermentability of these fibers in vitro and their effects on intestinal function relevant to laxation in vivo using MRI. METHODS: Each fiber was predigested prior to measuring gas production in vitro during 48-h anaerobic incubation with healthy fecal samples. We performed a randomized, 3-way crossover trial in 14 healthy volunteers who ingested 7.5 g fiber twice on the day prior to...
Source: The American Journal of Clinical Nutrition - July 3, 2020 Category: Nutrition Authors: Gunn D, Murthy R, Major G, Wilkinson-Smith V, Hoad C, Marciani L, Remes-Troche J, Gill S, Rossi M, Harris H, Ahn-Jarvis J, Warren F, Whelan K, Spiller R Tags: Am J Clin Nutr Source Type: research

Whole grain and dietary fiber intake and risk of colorectal cancer in the NIH-AARP Diet and Health Study cohort.
Abstract BACKGROUND: Whole grains and other foods containing fiber are thought to be inversely related to colorectal cancer (CRC). However, whether these associations reflect fiber or fiber source remains unclear. OBJECTIVES: We evaluated associations of whole grain and dietary fiber intake with CRC risk in the large NIH-AARP Diet and Health Study. METHODS: We used Cox proportional hazard models to estimate HRs and 95% CIs for whole grain and dietary fiber intake and risk of CRC among 478,994 US adults, aged 50-71 y. Diet was assessed using a self-administered FFQ at baseline in 1995-1996, and 10,200 inc...
Source: The American Journal of Clinical Nutrition - July 3, 2020 Category: Nutrition Authors: Hullings AG, Sinha R, Liao LM, Freedman ND, Graubard BI, Loftfield E Tags: Am J Clin Nutr Source Type: research

One-year changes in sugar-sweetened beverage consumers' purchases following implementation of a beverage tax: a longitudinal quasi-experiment.
CONCLUSIONS: A sweetened beverage tax was not associated with reduced taxed beverage purchases among SSB consumers 12 mo posttax in the full sample. Both secondary analyses excluding holiday purchasing or aggregating posttax time periods found reductions in taxed beverage purchases ranging from -4.9 to -12.5 ounces per day. Larger longitudinal studies are needed to further understand tax effects. PMID: 32619214 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - July 3, 2020 Category: Nutrition Authors: Lawman HG, Bleich SN, Yan J, Hua SV, Lowery CM, Peterhans A, LeVasseur MT, Mitra N, Gibson LA, Roberto CA Tags: Am J Clin Nutr Source Type: research

Glycemic index, glycemic load, and risk of coronary heart disease: a pan-European cohort study.
a O, Gómez JH, Tjønneland A, Sonestedt E, Trichopoulou A, Karakatsani A, Valanou E, Boer JMA, Verschuren WMM, Boutron-Ruault MC, Fagherazzi G, Madika AL, Bergmann MM, Schulze MB, Ferrari P, Freisling H, Lennon H, Sacerdote C, Masala G, Tumino R, Riboli E, Wareham NJ, Danesh J, Forouhi NG, Butterworth AS, Krogh V Abstract BACKGROUND: High carbohydrate intake raises blood triglycerides, glucose, and insulin; reduces HDLs; and may increase risk of coronary heart disease (CHD). Epidemiological studies indicate that high dietary glycemic index (GI) and glycemic load (GL) are associated with increased CHD ...
Source: The American Journal of Clinical Nutrition - July 3, 2020 Category: Nutrition Authors: Sieri S, Agnoli C, Grioni S, Weiderpass E, Mattiello A, Sluijs I, Sanchez MJ, Jakobsen MU, Sweeting M, van der Schouw YT, Nilsson LM, Wennberg P, Katzke VA, Kühn T, Overvad K, Tong TYN, Conchi MI, Quirós JR, García-Torrecillas JM, Mokoroa O, Gómez JH, Tags: Am J Clin Nutr Source Type: research

Iron absorption during pregnancy is underestimated when iron utilization by the placenta and fetus is ignored.
This study utilized data from stable iron isotope studies carried out in 68 women during the third trimester of pregnancy. Iron status indicators and stable iron isotopic enrichment were measured in maternal blood, umbilical cord blood, and placental tissue when available. Factors associated with iron isotope partitioning between the maternal, neonatal, and placental compartments were identified. RESULTS: On average, true maternal absorption of iron increased by 10% (from 19% to 21%) after accounting for absorbed iron present in the newborn (P 
Source: The American Journal of Clinical Nutrition - July 2, 2020 Category: Nutrition Authors: Delaney KM, Guillet R, Pressman EK, Caulfield LE, Zavaleta N, Abrams SA, O'Brien KO Tags: Am J Clin Nutr Source Type: research

A healthy lifestyle pattern and the risk of symptomatic gallstone disease: results from 2 prospective cohort studies.
Abstract BACKGROUND: Symptomatic gallstones cause high financial and disease burden for public health systems. The combined role of diet and other lifestyle factors has not been studied so far. OBJECTIVES: We aimed to investigate the association between an a priori defined healthy lifestyle score (HLS, including healthy diet, moderate alcohol and regular coffee intakes, never smoking, physical activity, and normal weight) and the risk of symptomatic gallstone disease, and to estimate the proportion of cases potentially preventable by lifestyle modification. METHODS: We followed 60,768 women from the Nurs...
Source: The American Journal of Clinical Nutrition - July 2, 2020 Category: Nutrition Authors: Wirth J, Joshi AD, Song M, Lee DH, Tabung FK, Fung TT, Chan AT, Weikert C, Leitzmann M, Willett WC, Giovannucci E, Wu K Tags: Am J Clin Nutr Source Type: research

Vitamin E absorption and kinetics in healthy women, as modulated by food and by fat, studied using 2 deuterium-labeled α-tocopherols in a 3-phase crossover design.
Vitamin E absorption and kinetics in healthy women, as modulated by food and by fat, studied using 2 deuterium-labeled α-tocopherols in a 3-phase crossover design. Am J Clin Nutr. 2020 Jul 01;112(1):239 Authors: PMID: 32607556 [PubMed - in process] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - July 1, 2020 Category: Nutrition Tags: Am J Clin Nutr Source Type: research

Effect of daily vitamin B-12 and folic acid supplementation on fracture incidence in elderly individuals with an elevated plasma homocysteine concentration: B-PROOF, a randomized controlled trial.
Authors: PMID: 32607557 [PubMed - in process] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - July 1, 2020 Category: Nutrition Tags: Am J Clin Nutr Source Type: research

Reply to A Salari-Moghaddam et al.
PMID: 32607558 [PubMed - in process] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - July 1, 2020 Category: Nutrition Authors: Li J, Hu FB Tags: Am J Clin Nutr Source Type: research

The protective association of linoleic acid against mortality might be under- or over-estimated.
PMID: 32607560 [PubMed - in process] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - July 1, 2020 Category: Nutrition Authors: Salari-Moghaddam A, Naghshi S, Larijani B, Esmaillzadeh A Tags: Am J Clin Nutr Source Type: research

Cumulative soft drink consumption is associated with insulin resistance in Mexican adults.
CONCLUSIONS: Our data support the hypothesis that, in Mexican adults, a higher soft drink consumption is associated with an increase in HOMA-IR, despite known risk factors. These findings support the need for reinforcing policies to reduce soft drink consumption in our population. PMID: 32597932 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - June 29, 2020 Category: Nutrition Authors: Rivera-Paredez B, Torres-Ibarra L, González-Morales R, Barrientos-Gutiérrez T, Hernández-López R, Ramírez P, León-Maldonado L, Velázquez-Cruz R, Denova-Gutiérrez E, Salmerón J Tags: Am J Clin Nutr Source Type: research

Added sugar and sugar-sweetened beverages are associated with increased postpartum weight gain and soluble fiber intake is associated with postpartum weight loss in Hispanic women from Southern California.
We examined Hispanic women from the longitudinal Southern California Mother's Milk Study (n = 99) at 1 and 6 mo postpartum. Maternal assessments included height, weight, and dietary intake based on 24-h diet recalls. We used multivariable linear regression to examine the relation between maternal diet and change in postpartum weight after adjusting for maternal age, height, and energy intake. RESULTS: Higher intake of added sugar was associated with postpartum weight gain (β: 0.05; 95% CI: 0.004, 0.10; P = 0.05). In addition, a half 8-ounce (8 fluid ounces = 236.6 mL) serving per day...
Source: The American Journal of Clinical Nutrition - June 29, 2020 Category: Nutrition Authors: Alderete TL, Wild LE, Mierau SM, Bailey MJ, Patterson WB, Berger PK, Jones RB, Plows JF, Goran MI Tags: Am J Clin Nutr Source Type: research

A role for selenium-dependent GPX1 in SARS-CoV-2 virulence.
PMID: 32592394 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - June 27, 2020 Category: Nutrition Authors: Seale LA, Torres DJ, Berry MJ, Pitts MW Tags: Am J Clin Nutr Source Type: research

Reply to LA Seale et al.
PMID: 32592400 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - June 27, 2020 Category: Nutrition Authors: Zhang J, Taylor EW, Bennett K, Saad R, Rayman MP Tags: Am J Clin Nutr Source Type: research

Absence of evidence is no evidence for absence of the phenomenon.
PMID: 32584964 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - June 25, 2020 Category: Nutrition Authors: Westerterp KR Tags: Am J Clin Nutr Source Type: research

Exploring the effect of vitamin D3 supplementation on surrogate biomarkers of cholesterol absorption and endogenous synthesis in patients with type 2 diabetes-randomized controlled trial.
CONCLUSIONS: Vitamin D3 supplementation for 24 wk had no significant effect on surrogate biomarkers of cholesterol absorption or endogenous synthesis, consistent with the lack of effect on serum cholesterol profile. Vitamin D3 supplementation resulted in greater reduction in campesterol concentrations in participants not using compared with those using cholesterol-lowering medications. Further studies are required.This trial was registered at clinicaltrials.gov as NCT01736865. PMID: 32559272 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - June 19, 2020 Category: Nutrition Authors: Meng H, Matthan NR, Angellotti E, Pittas AG, Lichtenstein AH Tags: Am J Clin Nutr Source Type: research

Limiting deconditioned muscle atrophy and strength loss with appropriate nutrition: can it be done?
PMID: 32559274 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - June 19, 2020 Category: Nutrition Authors: Millward DJ Tags: Am J Clin Nutr Source Type: research

COVID-19 pandemic and mitigation strategies: implications for maternal and child health and nutrition.
Abstract Coronavirus disease 2019 (COVID-19) continues to ravage health and economic metrics globally, including progress in maternal and child nutrition. Although there has been focus on rising rates of childhood wasting in the short term, maternal and child undernutrition rates are also likely to increase as a consequence of COVID-19 and its impacts on poverty, coverage of essential interventions, and access to appropriate nutritious foods. Key sectors at particular risk of collapse or reduced efficiency in the wake of COVID-19 include food systems, incomes, and social protection, health care services for women ...
Source: The American Journal of Clinical Nutrition - June 19, 2020 Category: Nutrition Authors: Akseer N, Kandru G, Keats EC, Bhutta ZA Tags: Am J Clin Nutr Source Type: research

Effects of a modestly lower carbohydrate diet in gestational diabetes: a randomized controlled trial.
Abstract BACKGROUND: Lower carbohydrate diets have the potential to improve glycemia but may increase ketonemia in women with gestational diabetes (GDM). We hypothesized that modestly lower carbohydrate intake would not increase ketonemia. OBJECTIVE: To compare blood ketone concentration, risk of ketonemia, and pregnancy outcomes in women with GDM randomly assigned to a lower carbohydrate diet or routine care. METHODS: Forty-six women aged (mean ± SEM) 33.3 ± 0.6 y and prepregnancy BMI 26.8 ± 0.9 kg/m2 were randomly assigned at 28.5 ± 0....
Source: The American Journal of Clinical Nutrition - June 15, 2020 Category: Nutrition Authors: Mijatovic J, Louie JCY, Buso MEC, Atkinson FS, Ross GP, Markovic TP, Brand-Miller JC Tags: Am J Clin Nutr Source Type: research

Effect of daily 2000 IU versus 800 IU vitamin D on blood pressure among adults age 60 years and older: a randomized clinical trial.
CONCLUSIONS: While daily 2000 IU and 800 IU vitamin D3 reduced mean systolic BP over 2 y to a small and similar extent, 2000 IU reduced mean systolic BP variability significantly more compared with 800 IU. However, without a placebo control group we cannot ascertain whether vitamin D supplementation effectively reduces BP.This trial was registered at www.clinicaltrials.gov as NCT00599807. PMID: 32542307 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - June 15, 2020 Category: Nutrition Authors: Abderhalden LA, Meyer S, Dawson-Hughes B, Orav EJ, Meyer U, de Godoi Rezende Costa Molino C, Theiler R, Stähelin HB, Ruschitzka F, Egli A, Forman JP, Willett WC, Bischoff-Ferrari HA Tags: Am J Clin Nutr Source Type: research

A novel botanical formula improves eye fatigue and dry eye: a randomized, double-blind, placebo-controlled study.
CONCLUSIONS: Our botanical formula improves eye fatigue, dry eye, and macular function without changing the retinal structure, and thus it could serve as an effective nutritional strategy in improving eye fatigue without causing serious side effects.Clinical Trial Registry: chictr.org.cn (ChiCTR1800018987). PMID: 32542334 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - June 15, 2020 Category: Nutrition Authors: Kan J, Wang M, Liu Y, Liu H, Chen L, Zhang X, Huang C, Liu BY, Gu Z, Du J Tags: Am J Clin Nutr Source Type: research

Weight suppression increases odds for future onset of anorexia nervosa, bulimia nervosa, and purging disorder, but not binge eating disorder.
CONCLUSIONS: The results provide novel evidence that weight suppression correlates with future onset of eating disorders characterized by dietary restriction or compensatory weight control behaviors and suggest weight-suppressed women constitute an important risk group to target with selective prevention programs.These trials were registered at clinicaltrials.gov as NCT01126918 and NCT01949649. PMID: 32534455 [PubMed - as supplied by publisher] (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - June 13, 2020 Category: Nutrition Authors: Stice E, Rohde P, Shaw H, Desjardins C Tags: Am J Clin Nutr Source Type: research