The effects of inulin-type fructans on cardiovascular disease risk factors: systematic review and meta-analysis of randomized controlled trials
CONCLUSION: ITF may reduce low-density lipoprotein, triglycerides, and body weight. However, due to low to very low CoE, further well-designed and executed trials are needed to confirm these effects.PROSPERO REGISTRATION NUMBER: CRD42019136745.PMID:38309832 | DOI:10.1016/j.ajcnut.2023.10.030 (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - February 3, 2024 Category: Nutrition Authors: Jhalok Ronjan Talukdar Matthew Cooper Lyuba Lyutvyn Dena Zeraatkar Rahim Ali Rachel Berbrier Sabrina Janes Vanessa Ha Pauline B Darling Mike Xue Alexandro Chu Fariha Chowdhury Hope E Harnack Louise Huang Mikail Malik Jacqui Powless Florence V Lavergne Xue Source Type: research

Metabolomics of Ramadan fasting and associated risk of chronic diseases
CONCLUSIONS: Ramadan fasting is associated with short-term favorable changes in the metabolic profile concerning risk of some chronic diseases. These findings should be further investigated in future, larger studies of longer follow-up with clinical outcomes.PMID:38301826 | DOI:10.1016/j.ajcnut.2024.01.019 (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - February 1, 2024 Category: Nutrition Authors: Rami Al-Jafar Rui Climaco Pinto Paul Elliott Konstantinos K Tsilidis Abbas Dehghan Source Type: research

Temporal gut microbiota variability and association with dietary patterns: from the one-year observational DCH-NG MAX study
CONCLUSIONS: In the DCH-NG MAX, 39% of the genera had an ICC>0.5 over one year, suggesting that these genera could be studied with health outcomes in prospective analyses with acceptable precision. Adherence to the Nordic, Mediterranean, and plant-based diets differed between bacterial subgroups and was associated with higher abundance of genera with fiber-degrading properties. Fruits, vegetables, whole grains/cereals, and nuts were frequently associated with these genera.PMID:38301827 | DOI:10.1016/j.ajcnut.2024.01.027 (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - February 1, 2024 Category: Nutrition Authors: Agnetha L Rostgaard-Hansen Anders Esberg Johan Dicksved Torben Hansen Erik Pelve Carl Brunius Jytte Halkj ær Anne Tj ønneland Ingegerd Johansson Rikard Landberg Source Type: research

The associations of serum vitamin D status and vitamin D supplements use with all-cause dementia, Alzheimer's disease, and vascular dementia: a UK Biobank based prospective cohort study
CONCLUSIONS: Although our findings indicate the potential benefits of vitamin D supplementation for dementia prevention, randomized controlled trials are essential for definitive evidence.PMID:38296029 | DOI:10.1016/j.ajcnut.2024.01.020 (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - January 31, 2024 Category: Nutrition Authors: Li-Ju Chen Sha Sha Hannah Stocker Hermann Brenner Ben Sch öttker Source Type: research

PKU in Adults: What do we know?
Am J Clin Nutr. 2024 Jan 29:S0002-9165(24)00060-1. doi: 10.1016/j.ajcnut.2024.01.023. Online ahead of print.NO ABSTRACTPMID:38296030 | DOI:10.1016/j.ajcnut.2024.01.023 (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - January 31, 2024 Category: Nutrition Authors: Robin Lachmann Mirjam Langeveld Source Type: research

Adaptation of nutritional risk screening tools may better predict response to nutritional treatment: a secondary analysis of the randomized controlled trial Effect of early nutritional therapy on Frailty, Functional Outcomes, and Recovery of malnourished medical inpatients Trial (EFFORT)
CONCLUSIONS: Adapting the NRS and MNA by including nutritional parameters only improves their ability to predict response to a nutrition intervention, but slightly reduces their overall prognostic performance. Scores dependent on disease severity may best be considered prognostic scores, whereas nutritional risk scores not including parameters reflecting disease severity may indeed improve a more personalized treatment approach for nourishment interventions. The trial was registered at clinicaltrials.gov as NCT02517476.PMID:38290574 | DOI:10.1016/j.ajcnut.2024.01.013 (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - January 30, 2024 Category: Nutrition Authors: Carla Wunderle Jolanda Siegenthaler David Seres Michael Owen-Michaane Pascal Tribolet Zeno Stanga Beat Mueller Philipp Schuetz Source Type: research

Effect of cinnamon spice on continuously monitored glycemic response in adults with prediabetes: a 4-week randomized controlled crossover trial
CONCLUSIONS: Cinnamon, a widely available and low-cost supplement, may contribute to better glucose control when added to the diet in people who have obesity-related prediabetes. This trial was registered at clinicaltrials.gov as NCT04342624.PMID:38290699 | DOI:10.1016/j.ajcnut.2024.01.008 (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - January 30, 2024 Category: Nutrition Authors: Hila Zelicha Jieping Yang Susanne M Henning Jianjun Huang Ru-Po Lee Gail Thames Edward H Livingston David Heber Zhaoping Li Source Type: research

Plant stanol consumption increases anti-COVID-19 antibody responses, independent of changes in serum cholesterol concentrations: a randomized controlled trial
CONCLUSIONS: Consuming plant stanols (4 g/d) affects immune responses to COVID-19 vaccinations, translating into increased serum anti-COVID-19 IgM concentrations in subjects with overweight/obesity. Only in IgG seroconverted subjects, serum anti-COVID-19 IgG concentrations also increases. These effects are independent of reductions in LDL cholesterol. These results suggest that this high-risk group for COVID-19 complications could benefit from plant stanol consumption. This trial was registered at clinicaltrials.gov as NCT04844346.PMID:38278364 | DOI:10.1016/j.ajcnut.2024.01.017 (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - January 26, 2024 Category: Nutrition Authors: Lieve van Brakel Ronald P Mensink Dieter L ütjohann Jogchum Plat Source Type: research

Dietary patterns and their associations with sociodemographic and lifestyle factors in adult survivors of childhood cancer: a cross-sectional study
CONCLUSIONS: Unhealthy dietary patterns are prevalent in adult survivors of childhood cancer, especially those with lower socioeconomic status and racial minorities. Interventions to improve diet and health in childhood cancer survivors need to concurrently address disparities that contribute to adherence to healthy dietary practices. This trial was registered at clinicaltrials.gov as NCT00760656 (https://classic.CLINICALTRIALS: gov/ct2/show/NCT00760656).PMID:38278365 | DOI:10.1016/j.ajcnut.2024.01.012 (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - January 26, 2024 Category: Nutrition Authors: Tuo Lan Mei Wang Matthew J Ehrhardt Jennifer Q Lanctot Shu Jiang Gregory T Armstrong Kirsten K Ness Melissa M Hudson Graham A Colditz Leslie L Robison Yikyung Park Source Type: research

Effect of lipid-based nutrient supplements on micronutrient status and hemoglobin among children with stunting: secondary analysis of a randomized controlled trial in Uganda
CONCLUSIONS: LNS supplementation increases Hb and improves iron, cobalamin, and folate status, but not vitamin A status among children with stunting. LNS should be considered for children with stunting. This trial was registered at ISRCTN as 13093195.PMID:38278366 | DOI:10.1016/j.ajcnut.2024.01.018 (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - January 26, 2024 Category: Nutrition Authors: Rolland Mutumba Hannah Pesu Joseph Mbabazi Eva Greibe Ebba Nexo Mette F Olsen Andr é Briend Christian M ølgaard Kim F Michaelsen Christian Ritz Suzanne Filteau Ezekiel Mupere Henrik Friis Benedikte Grenov Source Type: research

A low dose of daily licorice intake affects renin, aldosterone, and home blood pressure in a randomized crossover trial
CONCLUSIONS: We found licorice to be more potent than previously known, with significant increases in BP, after a daily intake of only 100 mg GA. Thus, the safe limit of intake of this substance might need to be reconsidered. This trial was registered at clinicaltrials.gov as NCT05661721 (https://clinicaltrials.gov/study/NCT05661721).PMID:38246526 | DOI:10.1016/j.ajcnut.2024.01.011 (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - January 21, 2024 Category: Nutrition Authors: Peder Af Geijerstam Annelie Joelsson Karin R ådholm Fredrik H Nystr öm Source Type: research

Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial and meta-analysis of 3 cognitive studies within COSMOS
CONCLUSIONS: In COSMOS-Clinic, daily MVM supplementation leads to a significantly more favorable 2-y change in episodic memory. The meta-analysis within COSMOS cognitive substudies indicates that daily MVM significantly benefits both global cognition and episodic memory. These findings within the COSMOS trial support the benefits of a daily MVM in preventing cognitive decline among older adults. This trial was registered at COSMOS-clinicaltrials.gov as NCT02422745, at COSMOS-Mind-clinicaltrials.gov as NCT03035201, and at COSMOS-Web-clinicaltrials.gov as NCT04582617.PMID:38244989 | DOI:10.1016/j.ajcnut.2023.12.011 (Source: ...
Source: The American Journal of Clinical Nutrition - January 20, 2024 Category: Nutrition Authors: Chirag M Vyas JoAnn E Manson Howard D Sesso Nancy R Cook Pamela M Rist Alison Weinberg M Vinayaga Moorthy Laura D Baker Mark A Espeland Lok-Kin Yeung Adam M Brickman Olivia I Okereke Source Type: research

Increased low-density lipoprotein cholesterol on a low-carbohydrate diet in adults with normal but not high body weight: A meta-analysis
CONCLUSIONS: A substantial increase in LDL cholesterol is likely for individuals with low but not high BMI with consumption of an LCD, findings that may help guide individualized nutritional management of cardiovascular disease risk. As carbohydrate restriction tends to improve other lipid and nonlipid risk factors, the clinical significance of isolated LDL cholesterol elevation in this context warrants investigation. This trial was registered at PROSPERO as CRD42022299278.PMID:38237807 | DOI:10.1016/j.ajcnut.2024.01.009 (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - January 18, 2024 Category: Nutrition Authors: Adrian Soto-Mota Yuscely Flores-Jurado Nicholas G Norwitz David Feldman Mark A Pereira Goodarz Danaei David S Ludwig Source Type: research

Protein intake and healthy aging: sooner rather than later?
Am J Clin Nutr. 2024 Feb;119(2):253-254. doi: 10.1016/j.ajcnut.2023.12.004. Epub 2024 Jan 17.NO ABSTRACTPMID:38238247 | DOI:10.1016/j.ajcnut.2023.12.004 (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - January 18, 2024 Category: Nutrition Authors: Adri án Carballo-Casla Rosario Ortol á Amaia Calder ón-Larrañaga Source Type: research

Creatine metabolism during pregnancy: advancing toward understanding
Am J Clin Nutr. 2024 Jan 16:S0002-9165(23)66359-2. doi: 10.1016/j.ajcnut.2023.12.026. Online ahead of print.NO ABSTRACTPMID:38233265 | DOI:10.1016/j.ajcnut.2023.12.026 (Source: The American Journal of Clinical Nutrition)
Source: The American Journal of Clinical Nutrition - January 17, 2024 Category: Nutrition Authors: Sergej M Ostojic Source Type: research