Germs, genes, and host defense
Cisca Wijmenga has a long standing interest in understanding the molecular basis of the host immune system and how genetic variation leads to dysregulation of a proper immune response. She is particular interested in diseases associated such an imbalance, in particular celiac disease (a common autoimmune disorder) and candidiasis (a common infectious agent causing sepsis) . Her research group focusing on the regulatory networks of immune cells and their perturbation by genetic variation or physiological stressors like infectious agents or dietary gluten. To this end she founded a functional genomics cohort (LIfeLines Deep)...
Source: Videocast - All Events - November 7, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video

NIH Research Festival: A Celebration of Intramural Science Plenary Session III: Chronic Inflammation
Most of the NIH institutes and centers are involved in studies for which chronic inflammation is a common denominator. Allergies, asthma, heart and circulatory disease, rheumatoid arthritis, inflammatory bowel disease, celiac disease, some cancers, multiple sclerosis, and possibly Alzheimer’s. These are just a few debilitating diseases that can originate partly or entirely from the immune system’s aggressive response to perceived harmful stimuli. Aging itself has been described as the totality of a lifetime of chronic inflammation. Better understanding the causes and control of chronic inflammation thus can lea...
Source: Videocast - All Events - September 15, 2015 Category: Journals (General) Tags: Upcoming Events Source Type: video