The characterization and comorbidities of heterozygous Bardet-Biedl syndrome carriers
Conclusion: We found that aside from the association with overweight and obesity, heterozygous BBS mutations did not appear to increase the predisposition of individuals to comorbidities and metabolic diseases. To gain a more comprehensive understanding of the genetic susceptibility associated with Bardet-Biedl Syndrome (BBS), further research is warranted.PMID:38617006 | PMC:PMC11008491 | DOI:10.7150/ijms.92766 (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - April 15, 2024 Category: Biomedical Science Authors: Meng-Hua Li I-Chieh Chen Hui-Wen Yang Hsin-Chien Yen Yung-Chieh Huang Chia-Chi Hsu Yi-Ming Chen Yu-Yuan Ke Source Type: research
Mental Health and Quality of Life in Chronic Kidney Disease Patients with Mild-to-Moderate Depression: A Retrospective Cohort Study of Mindfulness-Based Stress Reduction Therapy
CONCLUSION: MBSR can improve the mental health, sleep quality, and quality of life of CKD patients with mild-to-moderate depression, and improve psychological resilience and mindfulness.PMID:38622007 | PMC:PMC11015819 | DOI:10.62641/aep.v52i2.1600 (Source: Actas Espanolas de Psiquiatria)
Source: Actas Espanolas de Psiquiatria - April 15, 2024 Category: Psychiatry Authors: Xiumei Li Wei Gao Jie Yu Yanling Mao Haihong Gu Fang Li Dongmei Ren Source Type: research
Daprodustat: A Hypoxia-Inducible Factor-Prolyl Hydroxylase Inhibitor for Anemia of Chronic Kidney Disease
CONCLUSIONS: Daprodustat is a novel oral, non-iron therapy for treatment of anemia of CKD. It was Food and Drug Administration approved in 2023 in patients already receiving dialysis for at least 4 months but not in non-dialysis patients. Long-term data for safety and additional benefits are pending.PMID:38616529 | DOI:10.1177/10600280241241563 (Source: The Annals of Pharmacotherapy)
Source: The Annals of Pharmacotherapy - April 15, 2024 Category: Drugs & Pharmacology Authors: Haley N Johnson Lalita Prasad-Reddy Source Type: research
Nephrology: What You May Have Missed in 2023
This article highlights a selection of important nephrology studies published in 2023 that have relevance for nonnephrologist physicians. Four studies examined progression of chronic kidney disease or cardiovascular disease with respect to finerenone use, magnesium supplementation, iron markers, and COVID-19. Two studies examined treatments to improve specific aspects of chronic kidney disease management, including daprodustat to address anemia and patiromer to address hyperphosphatemia. One study showed that acetazolamide added to loop diuretics increased diuresis in acute decompensated heart failure across a wide range o...
Source: Annals of Internal Medicine - April 15, 2024 Category: Internal Medicine Authors: Ali A M AlHabobi Ashwaq M S Almutairi Danah A S Y Bohemid Ashwini R Sehgal Source Type: research
The characterization and comorbidities of heterozygous Bardet-Biedl syndrome carriers
Conclusion: We found that aside from the association with overweight and obesity, heterozygous BBS mutations did not appear to increase the predisposition of individuals to comorbidities and metabolic diseases. To gain a more comprehensive understanding of the genetic susceptibility associated with Bardet-Biedl Syndrome (BBS), further research is warranted.PMID:38617006 | PMC:PMC11008491 | DOI:10.7150/ijms.92766 (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - April 15, 2024 Category: Biomedical Science Authors: Meng-Hua Li I-Chieh Chen Hui-Wen Yang Hsin-Chien Yen Yung-Chieh Huang Chia-Chi Hsu Yi-Ming Chen Yu-Yuan Ke Source Type: research
Mental Health and Quality of Life in Chronic Kidney Disease Patients with Mild-to-Moderate Depression: A Retrospective Cohort Study of Mindfulness-Based Stress Reduction Therapy
CONCLUSION: MBSR can improve the mental health, sleep quality, and quality of life of CKD patients with mild-to-moderate depression, and improve psychological resilience and mindfulness.PMID:38622007 | PMC:PMC11015819 | DOI:10.62641/aep.v52i2.1600 (Source: Actas Espanolas de Psiquiatria)
Source: Actas Espanolas de Psiquiatria - April 15, 2024 Category: Psychiatry Authors: Xiumei Li Wei Gao Jie Yu Yanling Mao Haihong Gu Fang Li Dongmei Ren Source Type: research
Daprodustat: A Hypoxia-Inducible Factor-Prolyl Hydroxylase Inhibitor for Anemia of Chronic Kidney Disease
CONCLUSIONS: Daprodustat is a novel oral, non-iron therapy for treatment of anemia of CKD. It was Food and Drug Administration approved in 2023 in patients already receiving dialysis for at least 4 months but not in non-dialysis patients. Long-term data for safety and additional benefits are pending.PMID:38616529 | DOI:10.1177/10600280241241563 (Source: The Annals of Pharmacotherapy)
Source: The Annals of Pharmacotherapy - April 15, 2024 Category: Drugs & Pharmacology Authors: Haley N Johnson Lalita Prasad-Reddy Source Type: research
Associations between dietary potassium intake from different food sources and hyperkalemia in patients with chronic kidney disease
This study investigated the association between potassium intake from different food sources and hyperkalemia in patients with non-dialysis-dependent CKD. (Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - April 15, 2024 Category: Urology & Nephrology Authors: Nobuhisa Morimoto, Shingo Shioji, Yuichiro Akagi, Tamami Fujiki, Shintaro Mandai, Fumiaki Ando, Takayasu Mori, Koichiro Susa, Shotaro Naito, Eisei Sohara, Tatsuhiko Anzai, Kunihiko Takahashi, Wataru Akita, Akihito Ohta, Shinichi Uchida, Soichiro Iimori Tags: Original Research Source Type: research
Unlocking the Potential of Brewers ’ Spent Grain: A Sustainable Model to Use Beer for Better Outcome in Chronic Kidney Disease
The rising global incidence of chronic inflammatory diseases calls for innovative and sustainable medical solutions. Brewers ’ spent grain (BSG), a byproduct of beer production, presents a unique opportunity in this regard. This review explores the multifaceted health benefits of BSG, with a focus on managing chronic kidney disease (CKD). BSG is identified as a potent prebiotic with potential as a therapeutic agent in C KD. We emphasize the role of gut dysbiosis in CKD and discuss how BSG could help mitigate metabolic derangements resulting from dysbiosis and CKD. (Source: Journal of Renal Nutrition)
Source: Journal of Renal Nutrition - April 15, 2024 Category: Urology & Nephrology Authors: Babak Ghajavand, Carla Avesani, Peter Stenvinkel, Annette Bruchfeld Tags: Review Article Source Type: research
Role of serum pentraxin-3 levels in patients with and without diabetic nephropathy
ConclusionThis study concludes that serum PTX3 can be used as a diagnostic marker for DN before the development of apparent chronic kidney disease and PTX3 was found to be a better marker than hs-CRP for diagnosing DN. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - April 15, 2024 Category: Endocrinology Source Type: research
Integrating Specialist and Primary Care in Chronic Disease Management
Alongside efforts to develop new strategies for the early diagnosis and delayed progression of chronic kidney disease (CKD), it remains critical to implement existing interventions effectively. Since the patients who might benefit are asymptomatic and undiagnosed, the tasks of early diagnosis and intervention naturally belong to the primary care practitioners (PCPs) who are in regular contact with these as-yet undiagnosed patients. Despite PCPs ’ familiarity with preventive measures, such as smoking cessation, blood pressure control, and diabetes control, both time constraints and the need to stay up to date with current...
Source: JAMA Internal Medicine - April 15, 2024 Category: Internal Medicine Source Type: research
Electronic Health Record Population Health Management for Chronic Kidney Disease Care
This cluster randomized clinical trial examines the effectiveness of an electronic health record –based population health management intervention vs usual care for reducing chronic kidney disease progression. (Source: JAMA Internal Medicine)
Source: JAMA Internal Medicine - April 15, 2024 Category: Internal Medicine Source Type: research
Rotational Atherectomy in Women
While ischemic heart disease represents the leading cause of death among both women and men worldwide, gender-related differences in clinical presentation, disease management, response to therapies and outcomes are evident. Identifying and understanding sex-based disparities and remaining cognizant that optimal therapeutic approaches may differ for women and men with coronary disease is a priority in optimizing care for both genders. With respect to coronary revascularization, women referred for percutaneous coronary intervention (PCI) are significantly older than their male counterparts and have a higher prevalence of com...
Source: The American Journal of Cardiology - April 15, 2024 Category: Cardiology Authors: Craig R. Narins Tags: Editorial Source Type: research
Determinants of early chronic kidney disease in patients with recently diagnosed type 2 diabetes mellitus: a retrospective study from the Taiwan Diabetes Registry
We tried to identify the risk factor associate with early chronic kidney disease (CKD) in recently diagnosed type 2 diabetes mellitus patients by utilizing real-world data from Taiwan Diabetes Registry. (Source: BMC Nephrology)
Source: BMC Nephrology - April 15, 2024 Category: Urology & Nephrology Authors: Yun-Kai Yeh, Kuan-Hung Lin, Wayne Huey-Herng Sheu, Su-Huey Lo, Yen-Po Yeh, Chien-Ning Huang, Chii-Min Hwu and Chieh-Hsiang Lu Tags: Research Source Type: research
Renal outcome of living kidney donors aged more than 70 years
ConclusionsOlder donors tend to develop CKD stage3b within 5 years post-donation but with the potential of recovery. Healthy older people (aged ≥70 years) could be candidates for living donors under careful monitoring of kidney function after donation. (Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - April 14, 2024 Category: Urology & Nephrology Source Type: research
