Antihypertensive Medication and Fracture Risk in Older VA Nursing Home Residents
This cohort study using a target trial emulation approach assesses whether initiating antihypertensive medication is associated with increased fracture risk among older long-term Veterans Health Administration nursing home residents. (Source: JAMA Internal Medicine)
Source: JAMA Internal Medicine - April 22, 2024 Category: Internal Medicine Source Type: research

Blood Pressure Management and Falls in Nursing Home Residents
In this study, Dave et al harness national Veterans Health Administration (VHA) clinical data to examine the association between initiation of a new antihypertensive agent with the incidence of fall-related fractures in residents at VHA nursing homes, or community living centers. In this carefully designed study, residents who received a new antihypertensive agent had more than 2-fold greater risk of fractures compared with those who did not (adjusted hazard ratio [aHR], 2.42 [95% CI, 1.43-4.08]). This practice was also associated with 1.8-fold greater risk of serious falls (HR, 1.80 [95% CI, 1.52-2.13]) and 1.7-fold great...
Source: JAMA Internal Medicine - April 22, 2024 Category: Internal Medicine Source Type: research

Errors in Results and Discussion
This article was corrected online. (Source: JAMA Internal Medicine)
Source: JAMA Internal Medicine - April 22, 2024 Category: Internal Medicine Source Type: research

Electronic Health Record Population Health Management for Chronic Kidney Disease Care
This cluster randomized clinical trial examines the effectiveness of an electronic health record –based population health management intervention vs usual care for reducing chronic kidney disease progression. (Source: JAMA Internal Medicine)
Source: JAMA Internal Medicine - April 15, 2024 Category: Internal Medicine Source Type: research

SGLT2i vs Sulfonylureas for Gout Prevention Among Patients With Type 2 Diabetes Receiving Metformin
This cohort study uses target trial emulation to evaluate risk of incident gout and rate of recurrent gout flares in patients with type 2 diabetes initiating sodium-glucose cotransporter-2 inhibitors (SGLT2i) vs sulfonylurea. (Source: JAMA Internal Medicine)
Source: JAMA Internal Medicine - April 15, 2024 Category: Internal Medicine Source Type: research

Adverse Pregnancy Outcomes and Long-Term Mortality in Women
This cohort study aims to determine long-term mortality risks associated with 5 major adverse pregnancy outcomes in a large population-based cohort of women. (Source: JAMA Internal Medicine)
Source: JAMA Internal Medicine - April 15, 2024 Category: Internal Medicine Source Type: research

Acute Cardiac Events Among Hospitalized Older Adults With RSV Infection
This cross-sectional study examines the frequency and severity of acute cardiac events in hospitalized adults aged 50 years or older with respiratory syncytial virus infection. (Source: JAMA Internal Medicine)
Source: JAMA Internal Medicine - April 15, 2024 Category: Internal Medicine Source Type: research

Stigmatizing Language, Patient Demographics, and Errors in the Diagnostic Process
This cohort study assesses the association between stigmatizing language, demographic characteristics, and errors in the diagnostic process among hospitalized adults. (Source: JAMA Internal Medicine)
Source: JAMA Internal Medicine - April 15, 2024 Category: Internal Medicine Source Type: research

Integrating Specialist and Primary Care in Chronic Disease Management
Alongside efforts to develop new strategies for the early diagnosis and delayed progression of chronic kidney disease (CKD), it remains critical to implement existing interventions effectively. Since the patients who might benefit are asymptomatic and undiagnosed, the tasks of early diagnosis and intervention naturally belong to the primary care practitioners (PCPs) who are in regular contact with these as-yet undiagnosed patients. Despite PCPs ’ familiarity with preventive measures, such as smoking cessation, blood pressure control, and diabetes control, both time constraints and the need to stay up to date with current...
Source: JAMA Internal Medicine - April 15, 2024 Category: Internal Medicine Source Type: research

RSV Vaccination —The Juice Is Worth the Squeeze
In this issue of JAMA Internal Medicine, Woodruff et al present a cross-sectional study of patients 50 years and older who were hospitalized and tested positive for respiratory syncytial virus (RSV), reporting that 22% experienced an acute cardiac event, including acute exacerbation of heart failure or myocardial injury. The already high in-hospital mortality rate of 5% for older adults with RSV-associated hospitalizations was doubled among those experiencing a concurrent acute cardiac event. (Source: JAMA Internal Medicine)
Source: JAMA Internal Medicine - April 15, 2024 Category: Internal Medicine Source Type: research

Strengthening the Role of the NIH in the Firearm Violence Epidemic
This Viewpoint discusses the potential for the National Institutes of Health (NIH), the premier research entity in the world, to significantly strengthen its investment in preventing and reducing firearm-related harms. (Source: JAMA Internal Medicine)
Source: JAMA Internal Medicine - April 8, 2024 Category: Internal Medicine Source Type: research

I Read Health Information Online —Can I Trust It?
This JAMA Internal Medicine Patient Page describes what health misinformation is and how to find more reliable health information online. (Source: JAMA Internal Medicine)
Source: JAMA Internal Medicine - April 8, 2024 Category: Internal Medicine Source Type: research

Brief Intervention With Instant Messaging Support or Regular Text Messaging Support in Reducing Alcohol Use
This randomized clinical trial compares reductions in alcohol consumption among university students at risk of alcohol use disorder 6 months after receipt of an alcohol brief intervention followed by 3 months of either chat-based instant messaging support for alcohol reduction or short message service support. (Source: JAMA Internal Medicine)
Source: JAMA Internal Medicine - April 8, 2024 Category: Internal Medicine Source Type: research

d -Mannose for Prevention of Recurrent Urinary Tract Infection Among Women
This randomized clinical trial seeks to determine whether d-mannose taken for 6 months reduces the proportion of women with recurrent urinary tract infections experiencing a medically attended urinary tract infection. (Source: JAMA Internal Medicine)
Source: JAMA Internal Medicine - April 8, 2024 Category: Internal Medicine Source Type: research

Antibiotic-Sparing Prevention of Urinary Tract Infections
Approximately half of women experience a urinary tract infection (UTI) in their lifetime, and at least 1 in 4 women who experience an initial episode of UTI go on to have a recurrent infection. While antibiotics are the mainstay of treatment for isolated episodes of cystitis as well as suppression of recurrent episodes, much effort has been directed at identifying potential antibiotic-sparing strategies to prevent recurrent UTIs due to concern about the rise of antimicrobial-resistant organisms and adverse effects associated with antibiotics. Although guidelines from professional societies encourage the use of vaginal estr...
Source: JAMA Internal Medicine - April 8, 2024 Category: Internal Medicine Source Type: research