The effect of metabolic control, self-efficacy, and quality of life on emotional eating in the adolescents with type 1 diabetes mellitus
ConclusionAs a result of the study, it was found that self-efficacy and quality of life of adolescents with type 1 diabetes have an effect on emotional eating, while A1C values of adolescents have no effect on emotional eating. In future studies, it is recommended to add other factors that may affect the emotional eating behaviors of adolescents with diabetes and also to make different studies with a higher number of samples. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - June 30, 2020 Category: Endocrinology Source Type: research

Human APRIL and FGF-21 and adhesion molecules in relation to cognitive function in elderly diabetic patients
AbstractAimA diverse combination of etiologies such as vascular and inflammatory factors and social and physical inactivity may take place in the etiology of cognitive dysfunction (CD). Diabetes mellitus (DM) may contribute to CD over insulin resistance, inflammation, and vascular risk factors. However, mechanisms included in the process are not very clear. We aimed to investigate serum levels of selected biomarkers as a proliferation-inducing ligand (APRIL), FGF-21, P-selectin, soluble vascular cell, and intercellular adhesion molecules-1 (sVCAM-1 and sICAM-1) in elderly patients with DM in relation to cognitive function....
Source: International Journal of Diabetes in Developing Countries - June 25, 2020 Category: Endocrinology Source Type: research

Expression analysis of microRNA-155 in type 2 diabetes in Kashmiri population
ConclusionThe current results demonstrated that miR-155 may be involved in resistance against T2DM and may be negatively associated with clinical parameters of T2DM patients. The study was limited by its observational study design, so additional studies involving pathophysiology are required to clarify the role of miR-155 in T2DM. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - June 20, 2020 Category: Endocrinology Source Type: research

Correlates of fear of hypoglycemia among patients with type 1 and 2 diabetes mellitus in outpatient hospitals in Zambia
AbstractBackgroundSevere hypoglycemia is a burdensome complication of diabetes mellitus that can induce fear of hypoglycemia and contribute to suboptimal glycemic control. The challenge is to achieve and maintain adequate glycemic control while avoiding episodes of severe hypoglycemia. The purpose of the study was to determine how common fear of hypoglycemia was in Zambian out-patients with diabetes and also to explore correlates of fear of hypoglycemia.MethodsOne hundred fifty-seven individuals with types 1 and 2 diabetes participated in the study. Fear of Hypoglycemia Scale, Diabetes Self-Care Inventory, Problem Areas in...
Source: International Journal of Diabetes in Developing Countries - June 20, 2020 Category: Endocrinology Source Type: research

Economic menace of diabetes in India: a systematic review
ConclusionThe present study highlighted that diabetes poses a high economic burden on individuals/households. The study directed the need to arrange awareness campaign regarding diabetes and associated risk factors in order to minimise the burden of diabetes. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - June 17, 2020 Category: Endocrinology Source Type: research

Relationship between serum cystatin C level and pregnancy complications and abnormal glucose tolerance at 6-week postpartum in patients with gestational diabetes mellitus
This study aimed to investigate the relationship between serum cystatin C level and pregnancy complications and abnormal glucose tolerance at 6-week postpartum in patients with gestational diabetes mellitus (GDM).MethodsClinical data of 298 cases of GDM delivered in Taizhou People ’s Hospital from January 2017 to June 2018 were retrospectively analyzed. According to the level of cystatin C before delivery, they were divided into normal group (≤ 1.1 mg/L) and elevated group (>  1.1 mg/L). The general situation, complications of pregnancy, and the incidence of abnormal glucose tolerance at 6...
Source: International Journal of Diabetes in Developing Countries - June 17, 2020 Category: Endocrinology Source Type: research

SGLT2 inhibitor/GLP-1 receptor agonists as first step monotherapy —evidence and implications
(Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - June 16, 2020 Category: Endocrinology Source Type: research

Metformin use in T2D patients with reduced kidney function: reassuring, more evidence needed
(Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - June 9, 2020 Category: Endocrinology Source Type: research

Post COVID-19 diabetes care —lessons and challenges
(Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - June 4, 2020 Category: Endocrinology Source Type: research

A survey on intensity of statin therapy among diabetes mellitus patients in secondary care practice
AbstractObjectivesTo assess the prevalence of statin usage, intensity of statin therapy, and serum LDL cholesterol levels achieved in clinical diabetes mellitus population to analyze whether the recommendations of American College of Cardiology/American Heart Association ’s cholesterol guidelines 2013 (ACC/AHA cholesterol guidelines 2013) are achieved in them.MethodsFasting lipid profile values, prevalence of statin usage, and intensity of statin therapy among 306 diabetes mellitus patients in the age group of 40 to 75  years, visiting the medicine department of a secondary care hospital, were noted. Results wer...
Source: International Journal of Diabetes in Developing Countries - June 3, 2020 Category: Endocrinology Source Type: research

Understanding goals and challenges in type 2 diabetes mellitus management in India: Time to do more in diabetes
(Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - June 3, 2020 Category: Endocrinology Source Type: research

Inflammatory response and timeline of chronic complications in patients with type 1 and 2 diabetes mellitus
ConclusionOur study indicates a direct link between systemic inflammation and the timely progression of type 1 DM. In patients with type 2 DM, no statistical significance was found between the levels of studied biomarkers and the occurrence of microvascular complications. Nephropathy appeared sooner in type 1 DM patients, while retinopathy and neuropathy had a similar pattern of occurrence in both types of patients. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - May 26, 2020 Category: Endocrinology Source Type: research

A diabetes perception study among rural and urban individuals of West Bengal, India: are we ready for the pandemic?
ConclusionThe study reveals the need for effective diabetes-specific health awareness campaigns to address the rise of diabetes pandemic in resource-limited country like India. There is an urgent need to address unfounded fear of adverse reaction of insulin over extended use. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - May 26, 2020 Category: Endocrinology Source Type: research

Diabetic retinopathy and its association with low glomerular filtration rate: a cross-sectional analysis of diabetes patients of community clinics across India
AbstractAimsTo determine the prevalence of diabetic retinopathy (DR) in patients with T2DM having low estimated glomerular filtration rate (eGFR).MethodsA cross-sectional retrospective data analysis of T2DM patients ’ records who were screened for DR across Apollo Sugar Clinics from June 2016 to December 2016. DR was diagnosed through fundus examination; patients having eGFR values were grouped into eGFR
Source: International Journal of Diabetes in Developing Countries - May 22, 2020 Category: Endocrinology Source Type: research

A case-control study of mental health status of diabetic patients seen in Calabar, Nigeria
This study was aimed at assessing mental health status among diabetic patients in a developing country setting.MethodsCase-control study design was used, and subjects were recruited using random sampling method. Cases were recruited from medical wards and clinics in the University of Calabar Teaching Hospital, Calabar, for 14  weeks beginning mid-April through mid-July 2019. Age- and sex-matched non-diabetic normotensive controls were civil servants. Validated and pretested PHQ-9 instrument was used to assess mental health status, and clinical depression was defined as score> 10.p value was set at 0.05.Results...
Source: International Journal of Diabetes in Developing Countries - May 22, 2020 Category: Endocrinology Source Type: research

Diagnostic performance of HbA1c for detecting prediabetes and diabetes in Turkish adults
ConclusionHbA1c showed poor performance in diagnosis of diabetes and prediabetes. Instead, using HbA1c as a screening test with well-defined cutoff may offer practical and economical advantages greatly reducing the number of OGTTs required. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - May 18, 2020 Category: Endocrinology Source Type: research

Effect of liraglutide on epicardial adipose tissue thickness with echocardiography in patients with obese type 2 diabetes mellitus
AbstractBackgroundLiraglutide, an analogue of glucagon-like peptide 1 (GLP-1), indicated for the treatment of type 2 diabetes mellitus (T2DM), has shown the effect on loss of weight and adipose deposits. The study was to evaluate the effect of liraglutide on epicardial adipose tissue (EAT) with echocardiography in patients with obese T2DM controlled on liraglutide monotherapy.MethodsA single-arm follow-up research was performed in our study. Thirty-six subjects with obese T2DM were enrolled in the study, who were administered with liraglutide monotheraphy daily. The study period was 3  months. EAT thickness was measur...
Source: International Journal of Diabetes in Developing Countries - May 18, 2020 Category: Endocrinology Source Type: research

Prolonged diabetic ketoacidosis and glycemic fluctuations associated with dapagliflozin: a case report
ConclusionProlonged DKA may be a result of SGLT-2 inhibition and individualized treatment and follow-up should be performed instead of standard DKA treatment. Also, we suggest that we need to evaluate endogenous insulin reserves of the patients before starting a SGLT-2I treatment. We believe that in order to raise awareness, these cases should be reported. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - May 18, 2020 Category: Endocrinology Source Type: research

Sensorimotor impairments, postural instability, and risk of falling in older adults with diabetic peripheral neuropathy
AbstractBackgroundOlder adults with type 2 diabetes mellitus (DM) have high incidence of falls. The aim of this study was to compare sensorimotor functions, balance, mobility, fear of falling, and fall history in older people with DM (with and without neuropathy) and non-diabetic healthy controls.MethodsWe enrolled 153 participants aged 50 –70 years: 51 people with diabetic peripheral neuropathy (D-PN), 52 with diabetes without neuropathy (D-noPN), and 50 healthy controls (HC). Participants completed a fear of falling assessment and detailed test battery comprising sensorimotor functions, lower limb strength, co...
Source: International Journal of Diabetes in Developing Countries - May 13, 2020 Category: Endocrinology Source Type: research

Lockdown —the only solution to defeat COVID-19
(Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - May 6, 2020 Category: Endocrinology Source Type: research

The impact of limited and strategic blood glucose monitoring on metabolic control in a type 1 diabetes clinic in Central India
This study assessed whether the use of two SMBG tests per day improves glycemic control, measured by a change in HbA1c, in youth with T1D followed at the DREAM Trust (DT) in Nagpur, India.MethodsSingle-site prospective cohort study of youth ≤ 23 years of age with T1D ≥ 1 year followed by DT, who were provided with SMBG meters and two test strips per day. Patients received education regarding SMBG and how to respond to blood glucose values and trends. They were followed every 3 months with HbA1c and questionnaires for a total of 21 months.ResultsHbA1c declined significantly from 10.2 ...
Source: International Journal of Diabetes in Developing Countries - May 4, 2020 Category: Endocrinology Source Type: research

Optimal reference values for insulin sensitivity indices in Iranian healthy females: a population-based study
ConclusionThis study determined reference values for various insulin sensitivity indices in healthy Iranian women. These values can be used to define insulin sensitivity in women in epidemiological and clinical studies. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - April 21, 2020 Category: Endocrinology Source Type: research

Hypoglycemic, hypolipidemic, and hepatoprotective effects of Polyscias fulva (Hiern) Harms ethanolic bark extract in streptozotocin-induced diabetic Wistar rats
This study sought to examine the antidiabetic effects of ethanolic stem bark extract ofP. fulva in streptozotocin (STZ) –induced diabetic Wistar albino rats.MethodsDiabetes in rats was induced by intraperitoneal injection of STZ (50  mg/kg bwt) in experimental groups. Rats were divided into five groups (n = 5 per group): group 1, control; group 2, diabetic untreated rats; groups 3 and 4, diabetic rats on 200 and 400 mg/kg bwt/day of extract, respectively; and group 5, diabetic rats on metformin (100 mg/kg bwt/day). The rats received oral treatments daily for 21 days, and fasting blood ...
Source: International Journal of Diabetes in Developing Countries - April 14, 2020 Category: Endocrinology Source Type: research

Influence of yoga on status of lipid indices in type 2 diabetes mellitus subjects
AbstractBackgroundAtherogenic index of plasma (AIP) is a strong marker to predict the risk of atherosclerosis and cardiovascular disease (CVD). Diabetes alters the utilization of lipids and lipoproteins which cause diabetes-induced atherogenic dyslipidemia leading to CVD.ObjectivesThe study aims to determine whether yoga intervention influences lipid indices in type 2 diabetes mellitus subjects.MethodsA total of 104 persons with type 2 diabetes were included in this hospital-based prospective randomized trial. These were further randomized into non-yoga (n = 52) and yoga (n = 52) groups. Interve...
Source: International Journal of Diabetes in Developing Countries - March 30, 2020 Category: Endocrinology Source Type: research

Candidate gene association study of UCP3 variant rs1800849 with T2D in Mizo population of Northeast India
ConclusionThus, it is concluded that the present study could not replicate the association of variant rs1800849 with genetic susceptibility to T2D in the Mizo population group. This absence of association highlights the genetic heterogeneity prevalent in Indian population groups and warrants screening of other T2D candidate genes in Mizo population group. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - March 30, 2020 Category: Endocrinology Source Type: research

Correction to: The role of osteocalcin in mechanism of steroid induced diabetes mellitus
The manuscript used in the original version of this article was outdated. In this connection, the following errors were encountered. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - March 23, 2020 Category: Endocrinology Source Type: research

Diabetes education and basic insulin related knowledge assessment in nursing staff in a tertiary care hospital in India
ConclusionThis study shows a significant deficit in basic insulin-related knowledge in nursing staff. There is a need for continuous medical education of nursing staff to stay updated on Diabetes management. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - March 17, 2020 Category: Endocrinology Source Type: research

Association between hemoglobin A1c and acute ischemic stroke among patients with type-2 diabetes: a case-control study
AbstractBackgroundAt present, stroke is a major health burden and the leading cause of death and long-term disability in the elderly. Ischemic stroke is the most common stroke type in the Thai population. Causes of ischemic stroke are likely to be multifactorial.ObjectiveThe purpose of this study was to determine the association between hemoglobin A1c (HbA1c) and acute ischemic stroke (AIS) among Thai patients with type-2 diabetes (PTDs).MethodsA hospital-based case-control study was conducted among PTDs attending the Bhuddasothorn hospital with 100 cases and 300 controls from 2013 to 2016. Cases were defined as PTDs who h...
Source: International Journal of Diabetes in Developing Countries - March 3, 2020 Category: Endocrinology Source Type: research

Study on the expression of CD14  + CD16 + monocytes and VEGF in peripheral blood of patients with type 2 diabetes mellitus and diabetic macroangiopathy
AbstractObjectivesTo study the expression of CD14  + CD16 + monocytes and VEGF and the levels of serum adiponectin and MCP-1 in peripheral blood of patients with type 2 diabetes mellitus (T2DM) and diabetic macroangiopathy to understand the possible mechanism of inflammatory immune response in T2DM and diabetic macroangiopathy.MethodsPeripheral blood CD14  + CD16 + monocytes were detected by flow cytometry in 50 T2DM patients, 50 patients with diabetic macroangiopathy, and 20 healthy controls or normal controls who participated in outpatient physical examination, and used the Ficoll-Hypaq...
Source: International Journal of Diabetes in Developing Countries - March 3, 2020 Category: Endocrinology Source Type: research

Liver iron concentration is an independent risk factor for the prediabetic state in β-thalassemia patients
ConclusionBased on the findings, HOMA-IR and QUICKI can be applied as useful glycemic metabolism indices for predicting prediabetic and normoglycemic states among β-TM patients. Also, LIC was an independent risk factor for the prediabetic state. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - February 28, 2020 Category: Endocrinology Source Type: research

Diagnostic efficiency of diabetes in pregnancy study group of India versus World Health Organization 2013 criteria
This study aims to see the diagnostic efficiency of Diabetes in Pregnancy Study Group of India (DIPSI) criterion in context to World Health Organization (WHO) 2013 criterion for detection of AGT in pregnancy.MethodsPregnant mothers (n = 231; age, 26.07 ± 5.21 years; body mass index (BMI), 25.00 ± 4.09 kg/m2; mean  ± SD) were screened for AGT including gestational diabetes mellitus (GDM) and diabetes in pregnancy (DIP) from July 2016 to July 2017 in the “GDM Clinic” of BSMMU following WHO 2013 and DIPSI protocol with an interv...
Source: International Journal of Diabetes in Developing Countries - February 28, 2020 Category: Endocrinology Source Type: research

Vitamin B 12 and diabetes risk —myth or reality
(Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - February 27, 2020 Category: Endocrinology Source Type: research

Association of gestational diabetes mellitus with adverse pregnancy outcomes: our experience and meta-analysis
ConclusionsWomen with GDM still have an increased incidence of adverse pregnancy outcomes, which indicated that early prevention and clinical treatment of disease should be enhanced. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - February 21, 2020 Category: Endocrinology Source Type: research

Beliefs of Caribbean type 2 diabetes patients towards insulin therapy and prescription
ConclusionContrary to several reports, this study shows that insulin-na ïve Caribbean type 2 diabetes patients do not have a significant negative perception towards insulin therapy. This finding might be related to the socio-cultural background of the patients studied. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - February 19, 2020 Category: Endocrinology Source Type: research

Secular trends and rural-urban differences in endocrine and metabolic disease mortality in China: an age-period-cohort modeling of National Data
ConclusionIncreases in EMD mortality in China since 1991 can be explained primarily by the period effect, reflecting unhealthy lifestyles adapted along with rapid economic growth. The 100-year declines in cohort effect and the rural-urban differences could be largely attributed to the overall progress and rural-urban inequity in medical and healthcare. Future public health planning and decision-making must emphasize these two factors. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - February 19, 2020 Category: Endocrinology Source Type: research

Health-related quality of life of Pakistani adolescents with type 1 diabetes and their parents
ConclusionIt is imperative for health care professionals to be aware of the effect of diabetes on QOL as timely screening is important for better health care outcomes. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - February 15, 2020 Category: Endocrinology Source Type: research

Gestational diabetes mellitus, its associated factors, and the pregnancy outcomes among pregnant women attending tertiary care hospitals of Bhubaneswar, India
ConclusionEarly diagnosis and appropriate management of gestational diabetes among pregnant women may have far-reaching repercussions for maternal and child health. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - February 14, 2020 Category: Endocrinology Source Type: research

Changes in SFRP5, WNT5A, HbA1c, BMI, PBF, and insulin resistance in men with type 2 diabetes after 12  weeks of combined exercise (HIIT and resistance)
ConclusionThe improvement of type 2 diabetic men ’s health can be a result of increased anti-inflammatory factor SFRP5 and decreased inflammatory factor WNT5A through reduction of BMI and PBF.Trial registrationIRCT20151026024717N3 (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - February 11, 2020 Category: Endocrinology Source Type: research

ABCD score of & gt;  6 predicts diabetes remission following bariatric surgery
ConclusionBariatric surgery leads to substantial weight loss and amelioration of type 2 diabetes. An ABCD score of>  6 predicts diabetes remission following bariatric surgery, and is recommended as an aid for patient selection and counseling. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - February 8, 2020 Category: Endocrinology Source Type: research

Care burden and quality of life in mothers of children with type 1 diabetes mellitus
AbstractPurposeThis was a descriptive study to determine the care burden and quality of life of mothers of children with type 1 diabetes mellitus (T1DM) and the correlation between these two variables.MethodsThe sample consisted of 106 mothers of children with T1DM. Data were collected using a descriptive questionnaire, the Zarit Caregiver Burden Interview and WHOQOL-BREF quality of life scale, and were evaluated with the Mann-WhitneyU test, Student ’st test, ANOVA, Kruskal-Wallis test and Spearman ’s correlations.ResultsMothers had a moderate burden level (34.95  ± 12.48) with a statistica...
Source: International Journal of Diabetes in Developing Countries - February 8, 2020 Category: Endocrinology Source Type: research

The role of osteocalcin in mechanism of Steroid induced diabetes mellitus
ConclusionDecrease in serum osteocalcin level with increase in glycemic parameters in steroid induced diabetes group, point to have a new role in mechanism of steroid induced diabetes. This may be a novel target to discover drugs that can maintain the OC levels so that the effect of steroids on blood sugar level can be minimised. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - February 5, 2020 Category: Endocrinology Source Type: research

The novel mechanism of steroid-induced diabetes mellitus
ConclusionDecrease in serum osteocalcin level with increase in glycemic parameters in steroid-induced diabetic group points to the novel mechanism of steroid-induced diabetes. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - February 5, 2020 Category: Endocrinology Source Type: research

BDNF is obverse to oxidative stress (adenosine deaminase and nitric oxide) in type II diabetes mellitus
AbstractAimThe relational analysis of adenosine deaminase (ADA), nitric oxide (NO), BDNF (brain-derived neurotrophic factor), and TP (total protein) is accomplished by comparing these parameters with glucose levels of healthy and type II diabetes mellitus people. Type 2 diabetes (T2DM) is associated with impairment in many domains of cognitive function which may result from reduced BDNF. ADA is an important enzyme that plays a relevant role in purine and DNA metabolism, immune responses, and peptidase activity and for modulating the bioactivity of insulin. Nitric oxide is associated with loss of normal cellular function an...
Source: International Journal of Diabetes in Developing Countries - January 31, 2020 Category: Endocrinology Source Type: research

Gender-specific siblings and women with maternal history of diabetes are at high risk of developing type2 diabetes-a family study from South India
AbstractBackgroundRisk factors associated with diabetes (DM) are to be well studied, and this study was aimed to investigate the family transmission pattern of type 2 DM in South Indian population.MethodsA total of 3093 subjects were selected between June 2017 and May 2018. Details on family history of diabetes, treatment, and age at onset of DM were recorded. The subjects are divided into three groups based on family history risk categories maintained as registries. Group 1 (NPDR) (n = 1414) was with no parent diabetes, group 2 (OPDR) (n = 1216) with one parent diabetes, and group 3 (CPDR) (n&t...
Source: International Journal of Diabetes in Developing Countries - January 30, 2020 Category: Endocrinology Source Type: research

Pulmonary function tests in type 2 diabetes mellitus and their association with glycemic status and insulin resistance
AbstractIntroductionType 2 diabetes mellitus (T2DM) is associated with long-term complications in different organs, and this is attributable to macrovascular and microvascular changes as reported by Fowler. Pulmonary complications, however, have been poorly characterised.Materials and methodsThe present study was a case –control study done at SRN Hospital, Prayagraj to correlate the pulmonary functions with glycemic status and insulin resistance in 100 patients with diabetes (cases) and compare these parameters in patients without diabetes (controls). Baseline values of fasting plasma glucose (FPG), prandial plas ma ...
Source: International Journal of Diabetes in Developing Countries - January 30, 2020 Category: Endocrinology Source Type: research

Frameshift variance in SLC19A2 gene causing thiamine responsive megaloblastic anemia (TRMA): a case report from Pakistan
ConclusionThe diagnosis of TRMA should be kept in mind in differential diagnosis of DM with anemia and or sensorineural hearing loss. Particularly in the populations where the consanguinity is frequent as diagnosis has great impact on management. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - January 30, 2020 Category: Endocrinology Source Type: research

Prevalence and predictors of osteopenia and osteoporosis in patients with type 2 diabetes mellitus: a cross-sectional study from a tertiary care institute in North India
ConclusionThe prevalence of osteoporosis and osteopenia in patients with T2DM is high. Female gender, increasing age, normal BMI, low serum 25-hydroxyvitamin D, and pioglitazone use further increase the risk of osteoporosis. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - January 16, 2020 Category: Endocrinology Source Type: research

MACF1 gene variant rs2296172 is associated with T2D susceptibility in Mizo population from Northeast India
ConclusionThis study is the first replication report from Northeast India, showing variant rs2296172 of MACF1 gene associated with T2D in Mizo population. This independent study highlightsMACF1 as a candidate gene for T2D in Asian Indian populations, suggesting it is critical to evaluate the variant rs2296172 in other distinct endogamous Indian population cohorts. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - January 16, 2020 Category: Endocrinology Source Type: research

Irisin in elderly people with hypertension, diabetes mellitus type 2, and overweight and obesity
This study aimed to investigate the irisin levels in elderly patients with hypertension, diabetes mellitus type 2, and overweight and obesity, to investigate the possible association between irisin levels and anthropometric and biochemical parameters, and also to assess the irisin levels associated with a risk of hypertension, diabetes mellitus type 2, and overweight and obesity.MethodsA nested case-control study was conducted, with hypertension, diabetes mellitus type 2, and overweight and obesity being set as the case group; 71 elderly patients from the cohort were enrolled in each case group, and 71 healthy elderly from...
Source: International Journal of Diabetes in Developing Countries - January 16, 2020 Category: Endocrinology Source Type: research

Hematocrit levels and arterial stiffness: the Cardiometabolic Risk in Chinese (CRC) Study
ConclusionsIn adults in China, HCT level was associated with elevated central arterial stiffness, independent of conventional cardiovascular risk factors. As a serological marker, HCT can predict the degree of central arterial stiffness. HCT combined with other traditional cardiovascular risk factors can better assess vascular heart disease. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - January 15, 2020 Category: Endocrinology Source Type: research