International Journal of Diabetes in Developing Countries This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Effect of glycemic control and duration of type 2 diabetes on circulatory miR-146a in middle-aged Indians
ConclusionSignificant upregulation of plasma miR-146a indicated the increased risk of age-related pathologies in the middle-aged T2DM patients, which might allow taking effective therapeutic or lifestyle modification measures at an early stage. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - December 27, 2022 Category: Endocrinology Source Type: research

Nerve conduction study abnormalities in Indian children with type 1 diabetes
(Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - December 27, 2022 Category: Endocrinology Source Type: research

Rotational night shift work adversely affects expression of TCF7L2 and PPAR- γ genes among healthcare workers with normal glucose tolerance
ConclusionRotational night shift work adversely affects the expression of common diabetogenic genes TCF7L2 and PPAR- γ in healthcare workers with normal glucose tolerance. This suggests a possible role for the dysregulation of these genes in shift work associated diabetes risk. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - December 23, 2022 Category: Endocrinology Source Type: research

Molecular genetic analysis of the insulin gene variants in Iranian patients with permanent neonatal diabetes
ConclusionWe found that mutations inKCNJ11,INS, andABCC8 are not the common cause of PNDM in our population, and mutations inEIF2AK3,PTF1A, andGLIS3 genes are more frequent. The PNDM cases and their related reported mutation were related to the syndromic form of NDM, and all of them were diagnosed before 6 months of age. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - December 23, 2022 Category: Endocrinology Source Type: research

Maternally inherited diabetes and deafness (MIDD) —a series of case reports
ConclusionTo our knowledge, this is the largest series of MIDD reported from India. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - December 21, 2022 Category: Endocrinology Source Type: research

Study on the relationship between vitamin D level and macrophage typing in patients with type 2 diabetes mellitus
ConclusionsWhen the level of VitD in T2DM patients is low, there are more M1-type macrophages in peripheral blood, and when the level of VitD is increased, M2-type macrophages are increased. Changes in related inflammatory factors were also consistent. In vitro culture of monocytes further confirmed that VitD can promote the differentiation of macrophages to M2 type in T2DM patients. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - December 20, 2022 Category: Endocrinology Source Type: research

RSSDI Guidelines for the management of hypertension in patients with diabetes mellitus
AbstractHypertension and diabetes mellitus (DM) are two of the leading lifestyle diseases in the Indian and South Asian populations that often co-exist due to overlapping pathophysiological factors. Obesity, insulin resistance, inflammation, and oxidative stress are thought to be some common pathways. Up to 50% of hypertensive cases in India are diagnosed with type 2 diabetes mellitus (T2DM), which defines the need for a comprehensive guideline for managing hypertension in diabetic patients. These RSSDI guidelines have been formulated based on consultation with expert endocrinologists in India and Southeast Asia, acknowled...
Source: International Journal of Diabetes in Developing Countries - December 15, 2022 Category: Endocrinology Source Type: research

Study of relationship between glucagon level, glycemic status, and β-cell function in newly diagnosed T2DM patients, treated with insulin
ConclusionAmong newly diagnosed T2DM patients with moderate to severe hyperglycemia fasting glucagon correlated positively with glycemic status and negatively with insulin levels at baseline. Early and intensive insulin treatment was associated with good glycemic control and improvement in glucagon and insulin levels. A modest reciprocal correlation was noted between α- and β-cell function in these patients. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - December 13, 2022 Category: Endocrinology Source Type: research

The diagnostic characteristics of direct ophthalmoscopy for diabetic retinopathy screening by family physicians
ConclusionThis was the first study investigating the role of family physicians in DR screening in Iran. The results indicated that trained family physicians could be reliable enough for diagnosing DR with the help of a direct ophthalmoscope. They can be used as a part of a referral protocol in deprived areas where access to an ophthalmologist is difficult. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - December 11, 2022 Category: Endocrinology Source Type: research

Relationship between serum Vanin 1 level and metabolic parameters in patients with type 2 diabetes mellitus
ConclusionOur study showed that serum Vanin 1 level was higher in newly diagnosed diabetic patients compared to control group. Furthermore, serum Vanin 1 level exhibited a positive correlation with CIMT, waist circumference, BMI, HOMA-IR, and insulin resistance. These results suggest that Vanin 1, which is thought to have a potential role particularly in diabetes, as well as in CVD and metabolic syndrome, may be used as a potential therapeutic target and risk factor indicator in these diseases. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - December 8, 2022 Category: Endocrinology Source Type: research

Periodontal disease in fibrocalculous pancreatic diabetes (FCPD): common complication of an uncommon disease
ConclusionPD is common in FCPD like other forms of diabetes, and its severity correlates with glycemic control. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - December 5, 2022 Category: Endocrinology Source Type: research

Early menarche and premature menopause distributions based on diabetes status among postmenopausal women: a descriptive analysis from the IFLS study
(Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - November 30, 2022 Category: Endocrinology Source Type: research

Prevalence, risk factors, and self-awareness for hypertension and diabetes: rural –urban and male–female dimensions from a cross-sectional study in Ghana
ConclusionsOne third of the population were hypertensives but were unaware. Findings challenge the assumption of lower predisposition among rural inhabitants as we observe lifestyle habits consistent with increasing urbanisation. Efforts to mitigate rising NCD trend requires intensified community-based screening, awareness creation, and lifestyle interventions to improve diet, physical activity, and health seeking. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - November 29, 2022 Category: Endocrinology Source Type: research

Inadvertent intramuscular injection risk with subcutaneous insulin injections and risk predictors in adults: a cross-sectional sonographic study
ConclusionsThere is a high inadvertent intramuscular injection risk with currently used needles (8 and 13  mm) with U-100 syringes in our population even with a raised skin fold. To minimize this risk, 13-mm needles should be avoided when injecting insulin subcutaneously especially to the limbs. Sex and anthropometric parameters can be used to predict the distance from skin to muscle surface; hence, th e selection of needle length could be personalized based on the derived formulae. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - November 29, 2022 Category: Endocrinology Source Type: research

Prediction of gestational diabetes mellitus: are we ready for a biomarker lead screening strategy for GDM?
(Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - November 29, 2022 Category: Endocrinology Source Type: research