Association of serum osteocalcin with beta cell function, insulin resistance, and glycemic parameters in south Indian type 2 diabetic subjects
ConclusionSerum OC has significant association with insulin resistance and HbA1c in subjects with T2DM, which might suggest possible role of serum OC in glucose metabolism in T2DM. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - June 25, 2022 Category: Endocrinology Source Type: research

Shear wave elastography in evaluation of carotid elasticity in the type 2 diabetes mellitus patients with nonalcoholic fatty liver disease
ConclusionSWE can quantitatively evaluate the carotid elasticity of the T2DM patients with NAFLD. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - June 24, 2022 Category: Endocrinology Source Type: research

Follow-up frequency impacts metabolic control in diabetes patients under MMC framework —a retrospective study
ConclusionMMC improves the target-reaching rate of HbA1c, BP, and LDL-C for T2DM patients in China. Compared with follow-up<4 times/year, follow-up 4 times/year has the maximum benefit of metabolic control in patients while>4 times/year was found no additional benefits than 4 times/year. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - June 24, 2022 Category: Endocrinology Source Type: research

Improvement of biochemical and hematological parameters in alloxan-induced diabetic rats via administration of ethanol extract of Garcinia kola seeds
ConclusionG. Kola seeds possess antidiabetic activity and capability of restoring aberrated biochemical and hematological indices in diabetic rats. This research therefore consolidates its traditional use for the management of diabetes mellitus. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - June 22, 2022 Category: Endocrinology Source Type: research

Fear of hypoglycemia changes nutritional factors and behavioral strategies before the exercise in patients with type 1 diabetes mellitus
ConclusionsEvaluating the FoH and applying healthy behavioral and nutritional practices to prevent hypoglycemia will help patients reduce their stress perception and fear of hypoglycemia and contribute to the goal of glycemic control. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - June 17, 2022 Category: Endocrinology Source Type: research

Effects of 8-week high-intensity interval training and continuous aerobic training on asprosin secretion and fibrillin-1 gene expression levels in diabetic male rats
ConclusionsIt seems that diabetes has significant effects on increasing asprosin and FBN1 gene expression levels, while HIIT and CAT workouts have significant effects on decreasing asprosin and FBN1 gene expression levels. Therefore, both HIIT and CAT protocols can be utilized as significantly effective strategies for decreasing the levels of asprosin and its upstream gene, i.e., FBN1; thus, a combination of both strategies can be regarded as a useful intervention method for treating diabetes. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - June 17, 2022 Category: Endocrinology Source Type: research

Plasma carnitine, choline, γ-butyrobetaine, and trimethylamine-N-oxide, but not zonulin, are reduced in overweight/obese patients with pre/diabetes or impaired glycemia
ConclusionGiven the intergroup discrepancies in sIR, plasma zonulin, carnitine, choline, γ-BB, and TMAO along with their elective correlations with indices and clinical parameters of metabolic dysregulations, our study cannot rule out any possible molecular crosstalk and interplay of the biomarkers studied with the pathophysiology of prediabetes/diabetes. All in all, plasma zonulin, ca rnitine, choline, γ-BB, and TMAO with sIR can be putative surrogates for molecular cardiometabolic risk biomarkers to use as prognostic/predictive tools for the diagnosis/prevention and potential targets for prediabetes/diabetes management...
Source: International Journal of Diabetes in Developing Countries - June 14, 2022 Category: Endocrinology Source Type: research

Effects of dapagliflozin combined with short-term intensive insulin therapy on β-cell function in patients with newly diagnosed type 2 diabetes mellitus—a randomized controlled study
ConclusionDapagliflozin as add-on could reduce daily insulin dosage, but bring no additive effect in improving β-cell function for newly diagnosed T2DM patients receiving intensive insulin therapy.Trial registrationThe study was approved by the Chinese Clinical Trial Registry (ChiCTR.org.cn: ChiCTR1800015822). (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - June 14, 2022 Category: Endocrinology Source Type: research

An increased disulfide/native thiol ratio and oxidative stress index in metabolic syndrome patients with postprandial lipemia
ConclusionsAn increased disulfide/native thiol ratio and OSI level elevation in MetS may be closely associated with PPL. The disulfide/native thiol ratio in MetS subjects with PPL may play a role for evaluating oxidative stress, especially in postprandial 4th hour. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - June 14, 2022 Category: Endocrinology Source Type: research

Effect of stress hyperglycemia on admission and glycosylated hemoglobin on left ventricular function and inflammatory factors in patients with diabetes mellitus combined with myocardial infarction undergoing PCI
ConclusionsIn summary, in patients with diabetes mellitus combined with myocardial infarction and undergoing PCI on admission, stress hyperglycemia and high HbA1c levels were associated with higher FGB and 2hPG levels, which exacerbate ventricular functional impairment and inflammatory response, increase the risk of endpoint events, and can be predictors of patient prognosis. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - June 14, 2022 Category: Endocrinology Source Type: research

Correction to: Association of the Pro12Ala gene polymorphism with treatment response to thiazolidinediones in patients with type 2 diabetes: a meta-analysis
(Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - June 13, 2022 Category: Endocrinology Source Type: research

Could the PON1 phenotype play a key role in insulin resistance?
ConclusionIn this present study, the relationship between PON1 enzyme phenotypes and IR was evaluated for the first time in this field. Decreased PON1 activity and poor phenotype may also increase the development of hyperglycemia or diabetes mellitus (DM) due to IR and IFG. It may also predispose to diseases such as atherosclerosis. Therefore, we think that further investigations to explain the possible mechanisms underlying the relationship between PON1 phenotypes, IR and IFG will be useful in the early diagnosis and prevention ofprediabetes. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - June 8, 2022 Category: Endocrinology Source Type: research

National and regional prevalence rates of diabetes in Saudi Arabia: analysis of national survey data
ConclusionThis study showed the recent national and regional prevalence rates of DM among Saudi populations. The high prevalence of DM in Saudi Arabia requires an urgent public health call to improve early detection program and lifestyle interventions. This study urges to minimize the health and economic burden of DM by establishing and implementing a national diabetes prevention program. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - June 7, 2022 Category: Endocrinology Source Type: research

Comparison of inflammation-related hematologic indices for predicting metabolic syndrome in adults
ConclusionThe NHR index is a strong predictor of metabolic syndrome. In men, the NHR index is a better predictor of metabolic syndrome than the LHR index, and in women, the NHR index is better than the LHR and LMR. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - June 7, 2022 Category: Endocrinology Source Type: research

The effects of parental monitoring on the quality of life and diet quality of adolescents with type 1 diabetes
ConclusionsAs parental monitoring increases in adolescents with type 1 diabetes, the diet quality and quality of life of adolescents with diabetes also increase. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - June 4, 2022 Category: Endocrinology Source Type: research