Associations of the MTNR1B rs10830963 and PPARG rs1801282 variants with gestational diabetes mellitus: A meta-analysis
ConclusionsMTNR1B rs10830963(C  >  G) significantly increases the risk of GDM in Europeans, Asians, and Americans. G allele carriers in European population were confirmed a higher risk of GDM than Asian and American populations. No association between GDM and PPARG rs1801282 SNV indicates further validation may be needed. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - March 20, 2023 Category: Endocrinology Source Type: research

Bone mineral density and its predictors in a cohort of adults with type 1 diabetes attending a tertiary care institute in North India
ConclusionPatients of T1D have apparently reduced BMD, which is being influenced by BMI and serum albumin level. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - March 10, 2023 Category: Endocrinology Source Type: research

High molecular weight adiponectin and DXA-derived abdominal subcutaneous adipose tissue may independently protect against type 2 diabetes regardless of body mass index
ConclusionsHMW-adiponectin and DXA-derived abdominal SCAT may independently predict metabolic risk irrespective of BMI. Prospective studies need to explore whether paucity of abdominal SCAT could be one of several factors contributing to non-obese T2DM in Asian Indians. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - March 9, 2023 Category: Endocrinology Source Type: research

Diabetic myonecrosis of isolated internal oblique muscle, a rare presentation of an uncommon condition: A case report
AbstractIntroductionDiabetic myonecrosis is usually encountered in patients with long-standing diabetes mellitus, particularly those with uncontrolled glycemia and target organ damage. It is considered a form of microangiopathy and commonly involves large muscles of the lower extremities. Upper limb muscles are involved infrequently, and involvement of trunk muscles is extremely rare. Isolated involvement of abdominal muscle has never been reported so far.Case reportA 50-year-old gentleman with fifteen-year history of type 2 diabetes mellitus presented with pain and swelling of left lumbar region for the preceding two week...
Source: International Journal of Diabetes in Developing Countries - March 9, 2023 Category: Endocrinology Source Type: research

Personalized lifestyle change approaches for preventing type 2 diabetes in people with prediabetes
(Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - March 9, 2023 Category: Endocrinology Source Type: research

A multicentric, randomized, controlled trial of yoga and fenugreek in prevention of type 2 diabetes mellitus: methodological details —the Indian Prevention of Diabetes Study (IPDS)
AbstractPreliminary studies have shown that yoga as well as fenugreek are beneficial in patients with type 2 diabetes mellitus (T2DM). This clinical trial is the first of its kind to prospectively evaluate in a multicentric, randomized, and controlled design if yoga and fenugreek can prevent the composite outcome of T2DM in prediabetic individuals. It aims to investigate whether there is an effective and safe treatment modality for the prevention of T2DMwhich is also-cost effective and can be implemented easily on a large scale so as to reduce the burden of T2DM. One thousand five hundred obese prediabetic individual aged ...
Source: International Journal of Diabetes in Developing Countries - February 28, 2023 Category: Endocrinology Source Type: research

The association between thyroid hormone changes within the normal range and bone mineral density in patients with type 2 diabetes mellitus
ConclusionThe circulating concentration of FT3 was positively correlated with BMD. Maintaining normal and slightly higher levels of FT3 and SUA may prevent the reduction of BMD and the incidence of osteoporosis in T2DM patients. Besides, T2DM patients with TPOAb positive and TGAb positive levels should be routinely checked for BMD to prevent osteoporosis development. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - February 24, 2023 Category: Endocrinology Source Type: research

Case report: Maturity-Onset Diabetes of the Young (MODY12) caused by ABCC8 gene mutations
ConclusionThis case report highlights anABCC8 gene mutation in MODY12 that responds to sulfonylurea treatment. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - February 24, 2023 Category: Endocrinology Source Type: research

Circulating follistatin as a novel biomarker of type 2 diabetes mellitus risk
(Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - February 22, 2023 Category: Endocrinology Source Type: research

Diabetic retinopathy: An often missed window of opportunity
(Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - February 20, 2023 Category: Endocrinology Source Type: research

TNF- α levels, hypertension, glycated hemoglobin, and lower limb pain are predictors of diabetic neuropathy
(Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - February 15, 2023 Category: Endocrinology Source Type: research

Pancreoprivic diabetes: A clinico-etiological perspective from a single center in Andhra Pradesh, India
ConclusionPancreoprivic diabetes has a distinct pancreatic pathology, poor glycemic status, and low BMI. A high prevalence of pancreatic calcifications and neuropathy is seen. Besides APD, there are many other rare metabolic and anatomical etiologies. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - February 14, 2023 Category: Endocrinology Source Type: research

Benefits vs risks: SGLT-2 inhibitors in older adults living with frailty: a retrospective study from a university hospital
ConclusionPatients living with frailty are more vulnerable to adverse effects of SGLT-2 inhibitors, and their benefits are limited. Therefore, it should be used with caution in older adults with frailty. Longitudinal prospective studies should be conducted to support our findings. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - February 13, 2023 Category: Endocrinology Source Type: research

Identifying depressive symptoms in patients with type 2 diabetes mellitus: the role of glucose variability and concomitant hypothyroidism
ConclusionIncreased GV, particularly a joint increase in FBS and HbA1c variability as represented by the composite index, can indicate a significant increase in DS that can be detected even in small-scale clinical settings. Concomitant hypothyroidism, although managed according to the guidelines, can still be a risk factor for depression in diabetes. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - February 7, 2023 Category: Endocrinology Source Type: research

Incidence and predictors of metabolic syndrome in Asian-Indians: a 10-year population-based prospective cohort study
ConclusionAsian-Indians have a high incidence rate of metabolic syndrome, which is associated with sedentary lifestyle and consequent central obesity. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - February 7, 2023 Category: Endocrinology Source Type: research