The role of serum level of irisin in diabetic retinopathy
ConclusionIrisin may have value in screening diabetic retinopathy; however, further studies are needed for this proposal. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - September 13, 2023 Category: Endocrinology Source Type: research

Diabetic keto-acidosis in pancreatic diabetes  – how is it different from DKA in type 1 or type 2 DM?
ConclusionThis is the largest single-center cohort of T3DM with new-onset DKA, suggesting severe infections and glucocorticoid usage as major precipitating factors, while clinical course and outcomes were distinctly different from T2DM and T1DM patients with DKA. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - September 11, 2023 Category: Endocrinology Source Type: research

Achieving lipid goals in type 2 diabetic patients with dyslipidemia: barriers to treatment —the patient perspective
ConclusionIt was observed that 56.1% of type 2 diabetic patients were on statin therapy. A small percentage of them 14.8% (n = 42) reached the LDL target. Statin non-compliance and a lack of awareness of the statin treatment are the main reasons for high LDL levels in type 2 diabetic patients. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - September 11, 2023 Category: Endocrinology Source Type: research

Effect of dapagliflozin on the triglyceride-glucose index and the atherogenic index of plasma used as markers of atherosclerosis in patients with type 2 diabetes mellitus
ConclusionsDapagliflozin administration lowered the AIP and TyG index in patients with T2DM; this may slow the atherosclerotic process and prevent the associated macrovascular complications. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - September 11, 2023 Category: Endocrinology Source Type: research

Effects of preeclampsia on perinatal outcomes in women with gestational diabetes mellitus: A retrospective cohort study
ConclusionWomen with GDM complicated with preeclampsia were at higher risks of fetal malformations, fetal growth restriction, cesarean section, emergency cesarean section, preterm birth, LBW, SGA and neonatal hypoglycemia. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - September 8, 2023 Category: Endocrinology Source Type: research

Silencing of DIRAS3 improves the proliferation and insulin secretion of palmitic acid-treated pancreatic β‑cells through regulating PI3K/AKT signaling
ConclusionDIRAS3 was highly expressed in the cell models of type-2 diabetes mellitus, contributing to PA-induced cell death and impaired insulin secretion in pancreatic β-cells through the inhibition of the PI3K/AKT signalling pathway. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - September 4, 2023 Category: Endocrinology Source Type: research

Early effect of exenatide treatment on atherogenicity in patients with type 2 diabetes mellitus
ConclusionIn addition to its commonly known effects such as lowering FPG levels and weight loss, exenatide has been observed to have a positive effect on traditional lipid profiles and atherogenicity-related indices. In addition to its antidiabetic effect, it should be considered in diabetic patients in treatment options for atherosclerotic cardiovascular prevention. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - August 31, 2023 Category: Endocrinology Source Type: research

Bio-demographical determinants of diabetes among women in reproductive age group (15 –49) in India: Evidence from National Family Health Survey (NFHS) of India, 2019–2021
ConclusionThis study suggests that there is an urgent need for frequent monitoring of glycated haemoglobin (HbA1c). Besides, a spatially-optimized target-oriented policy framework is needed instead of a comprehensive national policy to tackle diabetes problems in the country. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - August 29, 2023 Category: Endocrinology Source Type: research

Usefulness of the Hypoglycemia awareness questionnaire in characterizing the Hypoglycemia events, proactive behaviors, and healthcare services used in patients with type 2 diabetes treated with insulin
ConclusionThe use of HypoA-Q questionnaire in usual clinical practice could facilitate the characterization of hypoglycemia events and the identification of at-risk populations by healthcare professionals and payers. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - August 29, 2023 Category: Endocrinology Source Type: research

Association of microalbuminuria with left ventricular diastolic dysfunction in type 2 diabetes mellitus
ConclusionThere is a significant correlation between microalbuminuria and LVDD in type 2 diabetes mellitus, independent of other parameters studied (age, sex, BMI, glycemic control, and duration of diabetes). (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - August 24, 2023 Category: Endocrinology Source Type: research

Correlation Analysis of Nutritional Status of Diabetic Foot Patients with Different Wagner Grades
ConclusionsThe nutritional status of patients with Wagner grading 3  ~ 5 is significantly worse than that of patients with Wagner grading 1–2. Age, duration of diabetes, HbA1c, WBC, Hb, albumin, and prealbumin have important effects on the development and prognosis of foot ulcers in patients with DF. Healthcare workers should give targeted interventions and ap propriate nutritional support through the screening and comprehensive consideration of relevant factors at an early stage in clinical practice in order to improve the general condition of patients, accelerate the purpose of ulcer healing, and thus improve the q...
Source: International Journal of Diabetes in Developing Countries - August 22, 2023 Category: Endocrinology Source Type: research

The effectiveness of selected temporary testing protocols for gestational diabetes during the COVID-19 pandemic
ConclusionsModifications proposed from the UK and Australia resulted in varying decreases and delays in GDM diagnoses, but with no apparent harm to mothers and offspring. More studies are required to investigate the impact of the simplification of GDM diagnosis on pregnancy outcomes. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - August 21, 2023 Category: Endocrinology Source Type: research

The effect of exercise training on serum Omentin-1 levels, glycemic control and body composition in adults population: a systematic review and meta-analysis of randomized controlled trials
ConclusionThese findings reveal that isolated aerobic and resistance exercises resulted in an increase in serum levels of Omentin-1 in adults. More high-quality studies are required to clarify the mechanisms underlying the influence of exercise training on Omentin-1 concentrations. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - August 21, 2023 Category: Endocrinology Source Type: research

The risk factors of early arterial stiffness in type 2 diabetes without diabetic macroangiopathy
ConclusionThe decline of arterial elasticity was common in T2DM patients without macroangiopathy. Elevated blood pressure, microangiopathy, chronic inflammation, and visceral fat accumulation were the risk factors of early arterial stiffness in patients with T2DM. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - August 21, 2023 Category: Endocrinology Source Type: research

Insulin glargine use and cancer risk among patients with type 2 diabetes mellitus: a real-world study in Shanghai, China
ConclusionInsulin glargine is not associated with the risk of overall and site-specific cancers compared to NPH insulin among patients with type 2 diabetes mellitus. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - August 10, 2023 Category: Endocrinology Source Type: research