International Journal of Diabetes in Developing Countries This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Relationship between impaired sensitivity to thyroid hormones and MAFLD with elevated liver enzymes in the euthyroid population
ConclusionsThese findings have important implications for understanding the role of thyroid hormone sensitivity in metabolic health, particularly in relation to MAFLD and associated complications such as elevated liver enzymes and FFAs. TFQIFT4, TFQIFT3, TSHI and TT4RI can be used as new indicators for predicting MAFLD and MAFLD with elevated liver enzymes. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - January 9, 2024 Category: Endocrinology Source Type: research

Assessment of equations estimating average glucose among patients with diabetic kidney disease before dialysis
ConclusionsHbA1c-derived estimated AG from existing equations may not accurately reflect measured AG in patients with DKD before dialysis. Diabetes type, BMI, and CKD stage should be considered when translating HbA1c into AG value in DKD before dialysis. It is advisable to adjust the AG-HbA1c equations for target population. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - January 8, 2024 Category: Endocrinology Source Type: research

The value of contrast-enhanced ultrasound in the diagnosis of microcirculatory perfusion abnormalities in diabetic foot
ConclusionsMicrocirculatory impairment in the dorsum of the foot in T2DM patients presents itself as “delayed wash-in, delayed wash-out, and weak enhancement” on CEUS images. CEUS can provide quantification of the microcirculatory changes in the soft tissues in the dorsum of the foot and reflect the differences of microcirculatory perfusion across different grades of lesions. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - January 5, 2024 Category: Endocrinology Source Type: research

The effects of sodium-glucose cotransporters type 2 inhibitors on glycemic and extraglycemic laboratory parameters
ConclusionWhile SGLT2i seem to provide positive effects on the lipid profile, as well as their well-recognized effects on glycemic parameters, there may be value in further evaluating renal safety and the long-term alterations in lipid profile. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - January 3, 2024 Category: Endocrinology Source Type: research

Cytokine gene polymorphism with type 2 diabetes and diabetic nephropathy in population from West India
ConclusionTheIL-6 -634C/G andIL-10-592 C/A polymorphisms were found to be associated with diabetic nephropathy in the West Indian population. The higher transcript level of inflammatory cytokines in patient groups compared to the control group may suggest the essential role of inflammation in the pathogenesis of diabetes and diabetic nephropathy. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - January 3, 2024 Category: Endocrinology Source Type: research

Poor accuracy of HbA1c for the diagnosis of prediabetes in overweight and obese Bangladeshi adults
ConclusionHbA1c was not accurate in the diagnosis of prediabetes in adults with BMI  ≥ 23 kg/m2. A higher cut-off value for HbA1c should be used for the diagnosis of prediabetes, but not diabetes. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - December 27, 2023 Category: Endocrinology Source Type: research

Parental monitoring status of the children with type 1 diabetes mellitus (DM) and their quality of life
ConclusionAlthough it was observed in the study that the levels of parental monitoring in type 1 diabetes care and pediatric quality of life were above the moderate level, parental monitoring was not found to affect children ’s quality of life. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - December 27, 2023 Category: Endocrinology Source Type: research

Clinical risk factors analysis and prevention of osteoporosis as a complication of diabetes
ConclusionHbA1c and fasting plasma glucose/fasting blood glucose were significantly correlated with bone metabolism in patients with type 2 diabetes with and without osteoporosis. Clinical monitoring of the HbA1c may be useful in preventing osteoporosis in patients with type 2 diabetes. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - December 27, 2023 Category: Endocrinology Source Type: research

Clinical reflections of diabetic nephropathy related pathological lesions
ConclusionThis large, single center, retrospective study reveals that diabetic retinopathy is associated with glomerular and arteriolar lesions but not with interstitial lesions. Proteinuria and hematuria were independent predictors of glomerular lesions, but not other renal lesions. Nevertheless, prospective studies which include all the confounding clinical factors are required to reach a conclusion on the relationship of hematuria and renal lesions. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - December 26, 2023 Category: Endocrinology Source Type: research

A retrospective electronic medical record-based study of insulin usage and outcomes in insulin-naive Indian adults with T2DM: The REALITY study
ConclusionThe REALITY study in India demonstrated that initiating basal insulin treatment in insulin-naive individuals with T2DM led to improved glycemic parameters over a 12-month period. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - December 15, 2023 Category: Endocrinology Source Type: research

The correlation between serum 1, 5-anhydroglucitol and β-cell function in Chinese adults with different glucose metabolism statuses
Conclusion: 1, 5-AG remained a factor for HOMA-β only for those with NUA. 1, 5-AG reflects different glucose metabolism statuses and is an auxiliary observation reflecting the secretory function of β cells in NUA patients. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - December 12, 2023 Category: Endocrinology Source Type: research

Association between nesfatin-1 hormone levels, anthropometric measurements, and glucose regulation shortly after sleeve gastrectomy: A  cross-sectional study
ConclusionsThis finding highlights the anorexigenic effects of nesfatin-1, and therefore, nesfatin-1 may be an effective factor in obesity treatment and diabetes. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - December 11, 2023 Category: Endocrinology Source Type: research

High expression of the glutathione S-transferase A2 and neuropilin-2 genes affects pancreatic islet β-cell function
ConclusionsThe results suggest that Nrp2 regulates apoptosis in Min6 cells and that there may be a link between this molecule and pathological apoptosis of pancreatic β-cells in T2DM patients. However, Gsta2 was not found to be an upstream regulator of Nrp2 in our cell line. Therefore, Gsta2 regulation of apoptosis in Min6 cells may be achieved through other apoptotic pathways. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - December 6, 2023 Category: Endocrinology Source Type: research

Multivariable prediction model of complications derived from diabetes mellitus using machine learning on scarce highly unbalanced data
ConclusionsThis ML model can be applied to predict CHD, CKD, and MOR. The success of ML predictions lies in the clinical definition of initial variables and their simplification for obtaining variables based on which the algorithms can identify patients that are likely to develop a complication. For clinical application of this system, it is necessary to assess the cross performance of metrics, as found here (accuracy higher 95% and F1-Score higher than 80%). (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - October 26, 2023 Category: Endocrinology Source Type: research

Inflammatory potential of the diet is associated with psychological stress in adults with type 2 diabetes: a methodological approach of e-Health
ConclusionUsing e-Health through web-based tools to collect information showed benefits of the application as a method of dietary assessment. We provide evidence showing that better values of the DII score and physical activity may play a protective role against the presence of psychological stress; DII and E-DII scores qualify and label habitual diet into pro and anti-inflammatory and are associated with psychological stress in T2D. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - October 23, 2023 Category: Endocrinology Source Type: research