Proportion of natural killer cells in peripheral blood lymphocytes is correlated with cytokine levels in patients with type 2 diabetes mellitus and prediabetes: a preliminary report
ConclusionsThe decreased proportion of NK cells in peripheral blood lymphocytes following some cytokine levels (IL-12p70, IL-6,IL-10 and IFN- γ) was likely involved in the development of T2DM and prediabetes. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - April 13, 2022 Category: Endocrinology Source Type: research

Association of serum level of chemerin with visceral fat obesity in type 2 diabetic patient
ConclusionNewly diagnosed diabetic subjects had low serum chemerin levels with obesity compared to healthy individuals, which could indicate a possibility of lifestyle modification practice in T2DM subjects. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - April 12, 2022 Category: Endocrinology Source Type: research

Correction to: Regular hospital visits and treatment outcomes among people living with type 1 diabetes: a 7-year study from South India
(Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - April 12, 2022 Category: Endocrinology Source Type: research

RSSDI consensus recommendations for dyslipidemia management in diabetes mellitus
AbstractDiabetic dyslipidemia is characterised by low HDL-C and high triglyceride levels. Unlike the Caucasian population, though LDL-C levels are not very high, there is a preponderance of more atherogenic small, dense LDL particles among Indians. Furthermore, apo B levels are elevated. This, unique ‘atherogenic dyslipidemia’, is frequently encountered in South Asians with diabetes. People with type 2 diabetes are considered to be at high risk for vascular events. Hence, irrespective of other risk factors such as age, male gender, hypertension, family history, smoking, obesity, and polycyst ic ovary syndrome in women,...
Source: International Journal of Diabetes in Developing Countries - April 7, 2022 Category: Endocrinology Source Type: research

Effects of an isometric exercise training program on muscular strength, ankle mobility, and balance in patients with diabetic peripheral neuropathy in the lower legs in South Africa
ConclusionsAlthough many of the changes noted were insignificant, the trends indicated an improvement in the intervention group over the 10-week intervention period. These improvements can be considered clinically important. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - April 5, 2022 Category: Endocrinology Source Type: research

MicroRNAs in diabetes mellitus —genetic tools that could transform clinical practice?
(Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - April 1, 2022 Category: Endocrinology Source Type: research

Maturity-onset diabetes of the young (MODY)-related genetic variants in a Turkish patient cohort with early-onset diabetes: a cross-sectional study
ConclusionMolecular genetic diagnosis of MODY is necessary for optimal follow-up, treatment, prognosis, and genetic counseling because of the close relationship between phenotype and genotype. Even in our small-sample-sized cohort, we were able to detect MODY variants with appropriate patient selection, and we re-evaluated for additional clinical features for the newly diagnosed MODY patients according to their variants, modified their treatment, and screened their first-degree relatives. This result presents that diabetic patients below 35 age, without low C-peptide levels and any positivity for beta-cell autoimmunity mar...
Source: International Journal of Diabetes in Developing Countries - March 30, 2022 Category: Endocrinology Source Type: research

Assessment of executive functions in subjects with type 2 diabetes mellitus
ConclusionOur study results support an association between executive dysfunction and type 2 DM. The poor glycemic control and longer duration of diabetes show a positive correlation with executive dysfunctions. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - March 25, 2022 Category: Endocrinology Source Type: research

Cost of diabetes treatment in private facilities for low resource urban community in South India
ConclusionPeople living with diabetes in low resource urban setting spent more toward direct medical cost. The out of pocket expenditure was mainly on hospitalization followed by medicines and investigations. The strengthening and provision of appropriate primary public health care services for diabetes in this setting may reduce out of pocket expenditure toward treatment of diabetes in private health care facilities.Highlights• Nearly 3/4th of study participants who earn INR 10,000/month monitor their diabetes status rarely, but take medicines alone.• They spend INR 6000 on medicines annually while they spend only INR...
Source: International Journal of Diabetes in Developing Countries - March 22, 2022 Category: Endocrinology Source Type: research

Regular hospital visits and treatment outcomes among people living with type 1 diabetes: a 7-year study from South India
ConclusionThe individuals who made a minimum of one or more than one hospital visit per year were found to have nil or lesser complications. Individuals who practiced SMBG had less complications compared to those not practicing SMBG. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - March 22, 2022 Category: Endocrinology Source Type: research

Comparison of serum cytokines between gestational diabetes mellitus and normal pregnancy women: a pilot study
ConclusionsOur results showed that the GDM patients developed a low-grade inflammatory state and presented a disorder of cytokines . These observations suggest that dysregulation of concentrations of pro- and anti-inflammatory cytokines in pregnancy is associated with GDM development. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - March 18, 2022 Category: Endocrinology Source Type: research

Serum asymmetric dimethylarginine (ADMA) level and cognitive dysfunction in diabetic patients
ConclusionThe involvement of ADMA in the pathogenesis of diabetic cognitive dysfunction is plausible and further studies are required to clarify the mechanism underlying the link of diabetic complications with cognitive decline. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - March 18, 2022 Category: Endocrinology Source Type: research

Correction to: A systematic review of diabetes risk assessment tools in sub-Saharan Africa
(Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - March 18, 2022 Category: Endocrinology Source Type: research

SNPs in the catalase promoter: a study based on Indian diabetic individuals
ConclusionOur reporter assay suggesting no functional relevance of promoter SNPs in reduced catalase activity observed in Indian diabetic individuals is a novel finding. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - March 11, 2022 Category: Endocrinology Source Type: research

Basic fibroblast growth factor alleviates metabolic abnormalities in the heart of streptozotocin-induced diabetic rats
ConclusionsOur results reveal that bFGF attenuated diabetic cardiac fibrosis and metabolic disorders mainly involving amino acid metabolism and energy metabolism. However, their causal associations still need to be further investigated. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - March 11, 2022 Category: Endocrinology Source Type: research