RSSDI consensus recommendations for dyslipidemia management in diabetes mellitus

AbstractDiabetic dyslipidemia is characterised by low HDL-C and high triglyceride levels. Unlike the Caucasian population, though LDL-C levels are not very high, there is a preponderance of more atherogenic small, dense LDL particles among Indians. Furthermore, apo B levels are elevated. This, unique ‘atherogenic dyslipidemia’, is frequently encountered in South Asians with diabetes. People with type 2 diabetes are considered to be at high risk for vascular events. Hence, irrespective of other risk factors such as age, male gender, hypertension, family history, smoking, obesity, and polycyst ic ovary syndrome in women, they must be screened for dyslipidemia. Other major ASCVD risk factors include family history of hyperlipidemia, low levels of HDL-C, hypertriglyceridemia, and increased levels of total serum cholesterol level, non-HDL-C, LDL-C, apo B, Lp(a), triglyceride-rich remnants, a nd small, dense LDL-C. In patients with diabetes, dyslipidemia should be assessed at diagnosis and annually thereafter. In patients with type 1 diabetes, screening for dyslipidemia should be initiated from the age of 12 years. Periodical screening for dyslipidemia is recommended in overweight or obe se children with a family history of type 2 diabetes, or those from a predisposed race/ethnicity like Asian, American Indian, etc. Both fasting and non-fasting lipid profiles are important for managing Indian patients with dyslipidemia. For routine screening, a fasting lipid profile is not mand...
Source: International Journal of Diabetes in Developing Countries - Category: Endocrinology Source Type: research