International Journal of Diabetes in Developing Countries This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Total cholesterol and postprandial triglyceride levels as early markers of GDM in Asian Indian women
ConclusionA combination of elevated fasting cholesterol and PPTg levels at an early stage of gestation can significantly predict future GDM. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - March 10, 2022 Category: Endocrinology Source Type: research

Role of ChREBP and SREBP-1c in gestational diabetes: two key players in glucose and lipid metabolism
AbstractBackgroundGestational diabetes mellitus (GDM) is any degree of glucose intolerance diagnosed during pregnancy. Metabolic abnormalities in GDM are associated with pancreatic β-cell destruction and decreased insulin sensitivity. Carbohydrate-responsive element-binding protein (ChREBP) and sterol regulatory element-binding protein-1c (SREBP-1c) are two transcription factors that play a key role in carbohydrate and lipid metabolism homeostasis. Our aim in this study was t o elucidate the role of these proteins in GDM.MethodsThe study included 50 pregnant women diagnosed with GDM and 52 pregnant women with normal gluco...
Source: International Journal of Diabetes in Developing Countries - March 10, 2022 Category: Endocrinology Source Type: research

Automation of insulin bolus dose calculation in type 1 diabetes: a feasibility study
ConclusionT1-life, integrated carbohydrate counting and reinforcement-based insulin bolus dose prediction system, has good patient usability and acceptability. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - March 9, 2022 Category: Endocrinology Source Type: research

Evaluation of drug utilization pattern of antidiabetic drugs and 10-year cardiovascular risk in new and recently diagnosed type 2 diabetes mellitus patients: a prospective, longitudinal, observational, hospital-based study
ConclusionThis study highlighted that patient education and periodic review of prescription of new and recently diagnosed diabetic patients play a vital role in managing type 2 diabetes mellitus by tailoring treatment regimen. The present study revealed overtreatment of low-risk groups and under-treatment of high-risk groups based on QRISK3 score and statins. This observation signifies that risk stratification is essential for preventing CVD risks in new diabetic patients. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - March 9, 2022 Category: Endocrinology Source Type: research

The relationship between treatment response and precursors of advanced glycation end-products in type 2 diabetes: a prospective case-control study
ConclusionThe level of AGE precursors was found to be significantly higher in diabetic patients than in the healthy control group. Although there was a significant decrease in AGE precursors when the HbA1c level fell in patients who followed anti-diabetic treatment and diabetes-appropriate diet recommendations, this decrease was at different rates in each patient, which demonstrated that the HbA1c level is not the only determinant of AGE level in plasma. It can be concluded that with appropriate diet and antidiabetic treatment, significant reductions can be obtained in several risk factors which increase the level of AGE p...
Source: International Journal of Diabetes in Developing Countries - March 3, 2022 Category: Endocrinology Source Type: research

Lipocalin-2 levels increase in plasma of non-alcoholic fatty liver disease patients with metabolic syndrome
ConclusionThe plasma lipocalin levels increase in NAFLD with metabolic syndrome and it can be considered a good blood biomarker. The early detection in NAFLD cases may improve prognosis. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - March 3, 2022 Category: Endocrinology Source Type: research

Comparison of metformin and insulin therapy for the treatment of gestational diabetes mellitus —a randomised controlled trial
ConclusionMetformin is as effective as insulin for control of blood sugar in women with GDM. Obese women and GDM diagnosed in first and second trimester may require addition of Insulin later. Most of the women preferred oral therapy with metformin initially and add insulin if needed. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - March 3, 2022 Category: Endocrinology Source Type: research

A systematic review of diabetes risk assessment tools in sub-Saharan Africa
ConclusionsThis systematic review demonstrated a paucity of validated diabetes risk assessment tools for SSA. There remains a need for the development and validation of a tool for the rapid identification of diabetes for targeted interventions. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - February 12, 2022 Category: Endocrinology Source Type: research

Expression profile of microRNAs may be promising in diagnosis of proliferative diabetic retinopathy: an Egyptian study
ConclusionMicroRNAs play a role in pathogenesis of diabetic retinopathy. In our study, miR-181c and miR-1179 were significantly high in PDR patients compared to NPDR and controls hence can be used to anticipate and follow up the progression. MicroRNA antagonists or mimics can be tried as new medications to modify DR by reducing the rate of progression, and subsequent blindness. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - February 3, 2022 Category: Endocrinology Source Type: research

Shotgun proteomic analysis using human serum from type 2 diabetes mellitus patients
ConclusionThese potential biomarker candidates might be verified by further experiments such as an ELISA assay or multiple reaction monitoring MS screening. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - January 30, 2022 Category: Endocrinology Source Type: research

Effectiveness of a diabetes educational intervention at primary school
ConclusionsActions like these must be encouraged within the school environment, especially in countries with high prevalence of diabetes. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - January 21, 2022 Category: Endocrinology Source Type: research

Role of third-trimester OGTT in the detection of late-onset gestational diabetes in the Indian population
ConclusionSince the incidence of detection of glucose intolerance was significantly high, our study implies the importance of screening in the third trimester of pregnancy, although there was not much difference in the adverse obstetric and neonatal outcomes. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - January 20, 2022 Category: Endocrinology Source Type: research

Detection of exudates from clinical fundus images using machine learning algorithms in diabetic maculopathy
AbstractPurpose of the studyAs per the estimation of the World Health Organization, around 400,000,000 people may be affected by diabetes in the year 2014. It is rapidly increasing double by the upcoming year 2030. Diabetic mellitus, also called diabetes, can cause critical issues of retinal disease such as diabetic retinopathy (DR) which causes blindness. Exudates are considered as the major sign of diabetic maculopathy (DM) which may lead to visual disturbances.MethodsThe main purpose is to develop a computer-aided technique for the detection of hard exudates to assist in the diagnosis of DR. It mainly focuses on the ide...
Source: International Journal of Diabetes in Developing Countries - January 15, 2022 Category: Endocrinology Source Type: research

The effect of 12  weeks of training in water on serum levels of SIRT1 and FGF-21, glycemic index, and lipid profile in patients with type 2 diabetes
ConclusionBased on results of the present study, it seems that exercise in water may play an effective role in glucose homeostasis and reduction of body fat mass, by increasing levels of SIRT1 and FGF-21 and it should be considered to prevent from development of type 2 diabetes. It can also be used as a type of exercise recommended by sports and health professionals in these people. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - January 14, 2022 Category: Endocrinology Source Type: research

Role of epicardial fat thickness for prediction of proliferative diabetic retinopathy
ConclusionWe suggest that MHR and EFT were significantly increased in proliferative DR, and increased EFT may predict the presence of PDR in type 2 DM. (Source: International Journal of Diabetes in Developing Countries)
Source: International Journal of Diabetes in Developing Countries - January 10, 2022 Category: Endocrinology Source Type: research