Tolvaptan therapy for edema in patients with chronic kidney disease
CONCLUSION: As long as a rational treatment regimen is followed, tolvaptan is a safe and effective diuretic for treating edema in CKD, even in the late stages of CKD without reducing residual renal function in the patients.PMID:38577748 | DOI:10.5414/CN111365 (Source: Clinical Nephrology)
Source: Clinical Nephrology - April 5, 2024 Category: Urology & Nephrology Authors: Li Zhou Qianqian Xu Xuehua Xi Xueying Yu Wenge Li Source Type: research

Disturbed flow in the juxta-anastomotic area of an arteriovenous fistula correlates with endothelial loss, acute thrombus formation and neointimal hyperplasia
CONCLUSION: Disturbed flow through the JAA correlates with rapid endothelial cell loss, thrombus formation, and JANIH; late endothelialization of the JAA channel correlates with late AVF patency. Early thrombus formation in the JAA may influence later development of JANIH.PMID:38578237 | DOI:10.1152/ajpheart.00054.2024 (Source: American Journal of Physiology. Heart and Circulatory Physiology)
Source: American Journal of Physiology. Heart and Circulatory Physiology - April 5, 2024 Category: Physiology Authors: Hualong Bai M Alyssa Varsanik Carly Thaxton Yuichi Ohashi Luis Gonzalez Weichang Zhang Yukihiko Aoyagi Masaki Kano Bogdan Yatsula Zhuo Li Luka Pocivavsek Alan Dardik Source Type: research

Tolvaptan therapy for edema in patients with chronic kidney disease
CONCLUSION: As long as a rational treatment regimen is followed, tolvaptan is a safe and effective diuretic for treating edema in CKD, even in the late stages of CKD without reducing residual renal function in the patients.PMID:38577748 | DOI:10.5414/CN111365 (Source: Clinical Nephrology)
Source: Clinical Nephrology - April 5, 2024 Category: Urology & Nephrology Authors: Li Zhou Qianqian Xu Xuehua Xi Xueying Yu Wenge Li Source Type: research

Disturbed flow in the juxta-anastomotic area of an arteriovenous fistula correlates with endothelial loss, acute thrombus formation and neointimal hyperplasia
CONCLUSION: Disturbed flow through the JAA correlates with rapid endothelial cell loss, thrombus formation, and JANIH; late endothelialization of the JAA channel correlates with late AVF patency. Early thrombus formation in the JAA may influence later development of JANIH.PMID:38578237 | DOI:10.1152/ajpheart.00054.2024 (Source: American Journal of Physiology. Heart and Circulatory Physiology)
Source: American Journal of Physiology. Heart and Circulatory Physiology - April 5, 2024 Category: Physiology Authors: Hualong Bai M Alyssa Varsanik Carly Thaxton Yuichi Ohashi Luis Gonzalez Weichang Zhang Yukihiko Aoyagi Masaki Kano Bogdan Yatsula Zhuo Li Luka Pocivavsek Alan Dardik Source Type: research

Correction to: Protein intake and its relationship with frailty in chronic kidney disease
(Source: Clinical and Experimental Nephrology)
Source: Clinical and Experimental Nephrology - April 5, 2024 Category: Urology & Nephrology Source Type: research

Pleural Effusion, Giardia, Adnexal Mass, Testosterone Replacement, Chronic Kidney Disease, Scalp Psoriasis
Am Fam Physician. 2024 Mar;109(3):208.NO ABSTRACTPMID:38574206 (Source: American Family Physician)
Source: American Family Physician - April 4, 2024 Category: Primary Care Source Type: research

PD-1 and LAG-3 positive T cells are related with the prognosis of patients with chronic kidney disease
CONCLUSION: In summary, the present research showed that the frequencies of LAG-3+ and PD-1+ T cells were remarkably enhanced in CKD patients. These findings offer novel insights and potential therapeutic targets for the management of CKD.PMID:38574959 | DOI:10.1016/j.yexcr.2024.114027 (Source: Experimental Cell Research)
Source: Experimental Cell Research - April 4, 2024 Category: Cytology Authors: Hongwei Jiang Jing Wu Junlin Zhang Source Type: research

PD-1 and LAG-3 positive T cells are related with the prognosis of patients with chronic kidney disease
CONCLUSION: In summary, the present research showed that the frequencies of LAG-3+ and PD-1+ T cells were remarkably enhanced in CKD patients. These findings offer novel insights and potential therapeutic targets for the management of CKD.PMID:38574959 | DOI:10.1016/j.yexcr.2024.114027 (Source: Cell Research)
Source: Cell Research - April 4, 2024 Category: Cytology Authors: Hongwei Jiang Jing Wu Junlin Zhang Source Type: research

Adenine-induced animal model of chronic kidney disease: current applications and future perspectives
This article reviews a widely used animal model of CKD, which is induced by adenine. While a physiologic dose of adenine is beneficial in terms of biological activity, a high dose of adenine is known to induce renal disease in the organism. Following a brief description of the procedure for disease induction by adenine, major mechanisms of adenine-induced CKD are then reviewed, including inflammation, oxidative stress, programmed cell death, metabolic disorders, and fibrillation. Finally, the application and future perspective of this adenine-induced CKD model as a platform for testing the efficacy of a variety of therapeu...
Source: Renal Failure - April 4, 2024 Category: Urology & Nephrology Authors: Qiao Yang Songya Su Nan Luo Gang Cao Source Type: research

Pleural Effusion, Giardia, Adnexal Mass, Testosterone Replacement, Chronic Kidney Disease, Scalp Psoriasis
Am Fam Physician. 2024 Mar;109(3):208.NO ABSTRACTPMID:38574206 (Source: American Family Physician)
Source: American Family Physician - April 4, 2024 Category: Primary Care Source Type: research

Strategies for prevention and treatment of SARS-COV-2 infection in patients with chronic kidney disease: Literature review
The objective of this review is to gather all treatment indications for COVID-19 in the different phases of the disease, tailored to CKD in its various stages, including renal replacement therapy.PMID:38575481 | DOI:10.1016/j.nefroe.2024.03.010 (Source: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia)
Source: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia - April 4, 2024 Category: Urology & Nephrology Authors: Mar ía Marques Vidas Elena Mu ñez Rubio Borja Quiroga Roc ío Montejano Enrique Morales Francisco Javier Candel Source Type: research

PD-1 and LAG-3 positive T cells are related with the prognosis of patients with chronic kidney disease
CONCLUSION: In summary, the present research showed that the frequencies of LAG-3+ and PD-1+ T cells were remarkably enhanced in CKD patients. These findings offer novel insights and potential therapeutic targets for the management of CKD.PMID:38574959 | DOI:10.1016/j.yexcr.2024.114027 (Source: Experimental Cell Research)
Source: Experimental Cell Research - April 4, 2024 Category: Cytology Authors: Hongwei Jiang Jing Wu Junlin Zhang Source Type: research

PD-1 and LAG-3 positive T cells are related with the prognosis of patients with chronic kidney disease
CONCLUSION: In summary, the present research showed that the frequencies of LAG-3+ and PD-1+ T cells were remarkably enhanced in CKD patients. These findings offer novel insights and potential therapeutic targets for the management of CKD.PMID:38574959 | DOI:10.1016/j.yexcr.2024.114027 (Source: Cell Research)
Source: Cell Research - April 4, 2024 Category: Cytology Authors: Hongwei Jiang Jing Wu Junlin Zhang Source Type: research

Adenine-induced animal model of chronic kidney disease: current applications and future perspectives
This article reviews a widely used animal model of CKD, which is induced by adenine. While a physiologic dose of adenine is beneficial in terms of biological activity, a high dose of adenine is known to induce renal disease in the organism. Following a brief description of the procedure for disease induction by adenine, major mechanisms of adenine-induced CKD are then reviewed, including inflammation, oxidative stress, programmed cell death, metabolic disorders, and fibrillation. Finally, the application and future perspective of this adenine-induced CKD model as a platform for testing the efficacy of a variety of therapeu...
Source: Renal Failure - April 4, 2024 Category: Urology & Nephrology Authors: Qiao Yang Songya Su Nan Luo Gang Cao Source Type: research