A nonlinear relationship between the triglycerides to high-density lipoprotein cholesterol ratio and stroke risk: an analysis based on data from the China Health and Retirement Longitudinal Study
The connection between triglycerides to high-density lipoprotein cholesterol (TG/HDL-C) ratio and stroke risk is controversial. Our goal was to explore this relationship in individuals aged 45 and older enroll... (Source: Diabetology and Metabolic Syndrome)
Source: Diabetology and Metabolic Syndrome - April 27, 2024 Category: Endocrinology Authors: Shike Zhang, Changchun Cao, Yong Han, Haofei Hu and Xiaodan Zheng Tags: Research Source Type: research
Associations between non-insulin-based insulin resistance indices and heart failure prevalence in overweight/obesity adults without diabetes mellitus: evidence from the NHANES 2001 –2018
The triglyceride glucose (TyG) index and triglyceride-to-high-density lipoprotein cholesterol (TG/HDL-C) ratio are recognized as simple non-insulin-based insulin resistance indices. Our study aimed to explore ... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - April 27, 2024 Category: Lipidology Authors: Di-yu Cui, Chao Zhang, Yi Chen, Gang-zhen Qian, Wan-xiang Zheng, Zhi-hui Zhang, Yu Zhang and Ping Zhu Tags: Research Source Type: research
Statin Therapy and Cardiovascular Protection in Type 2 Diabetes: The Role of Baseline LDL-Cholesterol Levels: A Systematic Review and Meta-analysis of Observational Studies
This study aimed to determine the association of statin use in T2D patients with major adverse cardiovascular events (MACE) and all-cause mortality and whether this association differs by baseline LDL-C levels. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - April 27, 2024 Category: Nutrition Authors: Negin Soroush, Mitra Nekouei Shahraki, Soroush Mohammadi Jouabadi, Masoud Amiri, Elif Aribas, Bruno H. Stricker, Fariba Ahmadizar Source Type: research
Association of cardiac biomarkers with long-term cardiovascular events in a community cohort
DISCUSSION: Ceramide score and NT proBNP improve the prediction of MACE and stroke/MI in a community primary prevention cohort.PMID:38666319 | DOI:10.1080/1354750X.2024.2335245 (Source: Biomarkers)
Source: Biomarkers - April 26, 2024 Category: Research Authors: Robert A Churchill Benjamin R Gochanour Christopher G Scott Vlad C Vasile Richard J Rodeheffer Jeffrey W Meeusen Allan S Jaffe Source Type: research
Prevalence of risk factors for development of cardiovascular diseases in urban and rural areas of Eastern Croatia: a cross-sectional study
CONCLUSIONS: In the examined sample, the prevalence of cardiovascular risk factors is generally high. Participants from rural areas are significantly more susceptible to cardiovascular risk factors than participants from urban areas.PMID:38669153 | DOI:10.21101/cejph.a7709 (Source: Central European Journal of Public Health)
Source: Central European Journal of Public Health - April 26, 2024 Category: International Medicine & Public Health Authors: Mirta Klapec-Basar Tanja Kova č Renata Apati ć Željko Mudri Tin Basar Stjepan Juri ć Rudika Gmajni ć Robert Lovri ć Source Type: research
Association of cardiac biomarkers with long-term cardiovascular events in a community cohort
DISCUSSION: Ceramide score and NT proBNP improve the prediction of MACE and stroke/MI in a community primary prevention cohort.PMID:38666319 | DOI:10.1080/1354750X.2024.2335245 (Source: Biomarkers)
Source: Biomarkers - April 26, 2024 Category: Research Authors: Robert A Churchill Benjamin R Gochanour Christopher G Scott Vlad C Vasile Richard J Rodeheffer Jeffrey W Meeusen Allan S Jaffe Source Type: research
Prevalence of risk factors for development of cardiovascular diseases in urban and rural areas of Eastern Croatia: a cross-sectional study
CONCLUSIONS: In the examined sample, the prevalence of cardiovascular risk factors is generally high. Participants from rural areas are significantly more susceptible to cardiovascular risk factors than participants from urban areas.PMID:38669153 | DOI:10.21101/cejph.a7709 (Source: Central European Journal of Public Health)
Source: Central European Journal of Public Health - April 26, 2024 Category: International Medicine & Public Health Authors: Mirta Klapec-Basar Tanja Kova č Renata Apati ć Željko Mudri Tin Basar Stjepan Juri ć Rudika Gmajni ć Robert Lovri ć Source Type: research
Association of cardiac biomarkers with long-term cardiovascular events in a community cohort
DISCUSSION: Ceramide score and NT proBNP improve the prediction of MACE and stroke/MI in a community primary prevention cohort.PMID:38666319 | DOI:10.1080/1354750X.2024.2335245 (Source: Biomarkers)
Source: Biomarkers - April 26, 2024 Category: Research Authors: Robert A Churchill Benjamin R Gochanour Christopher G Scott Vlad C Vasile Richard J Rodeheffer Jeffrey W Meeusen Allan S Jaffe Source Type: research
Prevalence of risk factors for development of cardiovascular diseases in urban and rural areas of Eastern Croatia: a cross-sectional study
CONCLUSIONS: In the examined sample, the prevalence of cardiovascular risk factors is generally high. Participants from rural areas are significantly more susceptible to cardiovascular risk factors than participants from urban areas.PMID:38669153 | DOI:10.21101/cejph.a7709 (Source: Central European Journal of Public Health)
Source: Central European Journal of Public Health - April 26, 2024 Category: International Medicine & Public Health Authors: Mirta Klapec-Basar Tanja Kova č Renata Apati ć Željko Mudri Tin Basar Stjepan Juri ć Rudika Gmajni ć Robert Lovri ć Source Type: research
Atherosclerosis Residual Lipid Risk-Overview of Existing and Future Pharmacotherapies
J Cardiovasc Dev Dis. 2024 Apr 21;11(4):126. doi: 10.3390/jcdd11040126.ABSTRACTPatients with atherosclerotic disease remain at increased risk of future events despite receiving optimal medical treatment. This residual risk is widely heterogeneous, but lipoprotein particles and their content play a major role in determining future cardiovascular events. Beyond low-density lipoprotein cholesterol (LDL-c), other lipoprotein particles have not demonstrated similar contribution to the progression of atherosclerosis. Statins, ezetimibe, and more recently, proprotein convertase subtilisin kexin 9 (PCSK9) inhibitors and bempedoic ...
Source: Atherosclerosis - April 26, 2024 Category: Cardiology Authors: Muntaser Omari Mohammad Alkhalil Source Type: research
Simplified Criteria for Identification of Familial Hypercholesterolemia in Children: Application in Real Life
CONCLUSIONS: In the pediatric population, the combination of LDL-C ≥95th percentile in the proband and the dominant inheritance pattern of hypercholesterolemia, with LDL-C ≥95th percentile in one parent, is a simple, useful and effective diagnostic criterion, showing high MDR. This pattern is crucial for early FH diagnosis. EAS, SBR and LIPIGEN-FH-PED criteria can underestimate the real number of patients with gene mutations and cannot be considered strictly discriminant for the execution of molecular analysis.PMID:38667741 | PMC:PMC11050898 | DOI:10.3390/jcdd11040123 (Source: Atherosclerosis)
Source: Atherosclerosis - April 26, 2024 Category: Cardiology Authors: Raffaele Buganza Giulia Massini Maria Donata Di Taranto Giovanna Cardiero Luisa de Sanctis Ornella Guardamagna Source Type: research
The Role of Fatty Acid Synthase in the Vascular Smooth Muscle Cell to Foam Cell Transition
Cells. 2024 Apr 9;13(8):658. doi: 10.3390/cells13080658.ABSTRACTVascular smooth muscle cells (VSMCs), in their contractile and differentiated state, are fundamental for maintaining vascular function. Upon exposure to cholesterol (CHO), VSMCs undergo dedifferentiation, adopting characteristics of foam cells-lipid-laden, macrophage-like cells pivotal in atherosclerotic plaque formation. CHO uptake by VSMCs leads to two primary pathways: ABCA1-mediated efflux or storage in lipid droplets as cholesterol esters (CEs). CE formation, involving the condensation of free CHO and fatty acids, is catalyzed by sterol O-acyltransferase ...
Source: Atherosclerosis - April 26, 2024 Category: Cardiology Authors: Bethany J Bogan Holly C Williams Claire M Holden Vraj Patel Giji Joseph Christopher Fierro Hugo Sepulveda W Robert Taylor Amir Rezvan Alejandra San Martin Source Type: research
A Novel Artificial Coronary Plaque to Model Coronary Heart Disease
CONCLUSION: This artificial atherosclerotic plaque model works as a simulating tool for future medical testing and could be crucial for further specified research on coronary artery disease and is going to help to provide information about the optimal interventional and surgical care of the disease.PMID:38667208 | PMC:PMC11048636 | DOI:10.3390/biomimetics9040197 (Source: Atherosclerosis)
Source: Atherosclerosis - April 26, 2024 Category: Cardiology Authors: Philipp Lindenhahn Jannik Richter Iliyana Pepelanova Bettina Seeger Holger A Volk Rabea Hinkel Bernhard Hiebl Thomas Scheper Jan B Hinrichs Lena S Becker Axel Haverich Tim Kaufeld Source Type: research
The Interplay of Microbiome Dysbiosis and Cardiovascular Disease
Cardiol Rev. 2024 Apr 26. doi: 10.1097/CRD.0000000000000701. Online ahead of print.ABSTRACTThe intricate ecosystem of the mammalian gut, which hosts a diverse microbiome, plays a vital role in various physiological functions. Trillions of bacteria within the gut contribute to host metabolism, immune modulation, energy homeostasis, and more. Emerging research highlights the gut microbiota's significant impact on cardiovascular diseases (CVDs), with intestinal dysbiosis identified as a risk factor for conditions such as obesity and diabetes, both linked to atherosclerosis. Chronic inflammation, pivotal in atherosclerosis, is...
Source: Atherosclerosis - April 26, 2024 Category: Cardiology Authors: Anas Zaher Jude Elsaygh Stephen J Peterson Ilan S Weisberg Manish A Parikh William H Frishman Source Type: research
Association of cardiac biomarkers with long-term cardiovascular events in a community cohort
DISCUSSION: Ceramide score and NT proBNP improve the prediction of MACE and stroke/MI in a community primary prevention cohort.PMID:38666319 | DOI:10.1080/1354750X.2024.2335245 (Source: Biomarkers)
Source: Biomarkers - April 26, 2024 Category: Research Authors: Robert A Churchill Benjamin R Gochanour Christopher G Scott Vlad C Vasile Richard J Rodeheffer Jeffrey W Meeusen Allan S Jaffe Source Type: research
