Effect of palmitate and oleate on mitochondrial dynamics processes in hepatic cells HEPG2
Introduction: Mitochondria are organelles constantly submitted to fusion and fission processes (mitochondrial dynamics). Fission process is associated with mitochondrial disfunction, oxidative stress and apoptosis, and therefore with insulin resistance onset. On the other hand, fusion process is associated with the prevention of this metabolic alteration, being able to protect cells against insulin resistance. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Isy Faria de Sousa, Marilena Lepretti, Vincenzo Migliaccio, Gaetana Paolella, Eliane Beraldi Ribeiro, Lill à Lionetti Source Type: research

Activation of cytostatic autophagy by polar extract of hempseed oil (Cannabis sativa L.) in a colorectal adenocarcinoma cell line
Introduction: The hempseed oil, suitable for human feeding, can be obtained by cold pressing of seed belonging to a non-pharmaceutical hemp variety (Cannabis sativa L.). Beyond its nutritional value due to the ideal ratio (3:1) of essential polyunsaturated fatty acids, the presence of biomolecules, such as phytocannabinoids and polyphenols, has been also associated with potential beneficial effects. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Stefania Moccia, Maria Russo, Carmela Spagnuolo, Idolo Tedesco, Gianluca Picariello, Francesco Siano, Maria Grazia Volpe, Francesco La Cara, Gian Luigi Russo Source Type: research

A Phenolic Extract from Extra Virgin Olive Oil Induces Authophagy and Apopotosis in Human Bladder Cancer Cell Lines Depending on Tumor Progression
Introduction: The regular consumption of olive oil has associated with a protection against several diseases, including cancer. Epidemiological evidence indicate an inverse association between olive oil intake and bladder cancer risk. The phenolic fraction of olive oil plays a key role in this beneficial effect. Bladder cancer is one of the most common cancer in Europe, United States and Nord Africa. In particular, the transitional cell carcinoma histotype shows an aggressive behavior and the current therapies are ineffective. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Carmela Spagnuolo, Filomena Maria Conte, Maria Russo, Idolo Tedesco, Stefania Moccia, Maria Sicuranza, Rossella Scotti, Gian Luigi Russo Source Type: research

Red Wine Polyphenols Induce Adaptive Response in a Monocyte/Macrophage Murine Cell Line (J774)
Introduction: Recent studies confirmed that a moderate amount of wine may have health benefits. Experimental evidence suggested that these beneficial effects could be due to the polyphenol content of red wine. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Idolo Tedesco, Michela Russo, Carla Cicala, Maria Russo, Stefania Moccia, Carmela Spagnuolo, Gian Luigi Russo Source Type: research

Vitamin D analogue EB1089 sensitizes human transformed cell lines to gamma radiations by inducing lethal autophagy and apoptosis
Introduction: The gold standard for unresectable solid tumours and advanced forms of leukemia is represented by chemo-radiation. However, therapeutic options are limited and patients undergo systemic cytotoxicity. Vitamin D insufficiency is a widespread problem and its low serum levels are linked to higher cancer incidence. Previous studies showed a strong correlation between serum concentration of vitamin D and time of first treatment in chronic lymphocytic leukemia (CLL). Other studies demonstrated that vitamin D and its ipocalcemic analogue EB1089 are able to bypass radio-resistance in breast and lung cancer cell lines ...
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Maria Russo, Mariangela Basile, Francesco Messano, Stefania Moccia, Carmela Spagnuolo, Idolo Tedesco, Gian Luigi Russo Source Type: research

Autophagy flux modulation by a carotenoid-enriched extract from the pumpkin Cucurbita moschata on human chronic lymphocytic leukemia cell line
Introduction: Chronic lymphocytic leukemia (CLL) is the most frequent form of leukemia in adult population and chemotherapy resistance occurs in 15 –30% of patients with elevated genomic complexity. Apoptosis resistance and induction of a protective form of autophagy are possible explanations of the poor responsivity of CLL to conventional and novel therapeutic drugs. Given the difficulties to maintain in culture B-CLL lymphocytes, the HG3 ce ll line represents an interesting preclinical model to study the effects of natural bioactive molecules or extracts derived from food matrix as potential, chemo-sensitizers in C...
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Maria Russo, Stefania Moccia, Carmela Spagnuolo, Idolo Tedesco, Carmen Cervellera, Gian Luigi Russo Source Type: research

Anti-inflammatory effects of blueberry extract in microglial cells
Background: Microglia (MG), the immunocompetent cells of the CNS, respond to brain injury activating and modifying their morphology. Microglia can exist broadly between two different activation states, namely the classical (M1) and the alternative activated (M2) phenotype. The first one is characterized by the production of pro-inflammatory cytokines, in contrast, the latter is characterized by the production of anti-inflammatory cytokines (Kettenmann et al., Neuron. 2013; 77:10 –18). Blueberry is involved in the control of the redox state of the cell, cooperating with antioxidant mechanisms, whereas its anti-inflamm...
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Maria Giovanna De Caris, Elisa Maggi, Antonio Francioso, Maddalena Grieco, Luciana Mosca, Maria D'Erme, Alessandro Pinto, Patrizia Mancini, Rita Businaro Source Type: research

Intestinal epithelium responses to titanium dioxide nanoparticles
Introduction: Humans are exposed to nanoparticles from a variety of sources through a broad range of exposure ways since nanomaterials are increasingly used in different productive sectors. Titanium dioxide (TiO2) is enclosed in many consumer products including pharmaceuticals, cosmetics, and foods. TiO2 (E171) is daily ingested as mixed nano- and submicron-sized particles since it is approved as a white pigment in Europe in a variety of food products. Noteworthy, the relevant risk assessment has never been satisfactorily concluded and growing alarms for human hazards deriving from TiO2 exposure are incrementally reported....
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Antonella Venezia, Paola Pedata, Giulia Ricci, Livia Malorni, Nunzia Iannaccone, Marcella Cammarota, Maria Grazia Volpe, Vincenzo Guida, Chiara Schirardi, Marco Romano, Giuseppe Iacomino Source Type: research

Interplay between the toxic alpha-gliadin peptide 31-43 and type 2 transglutaminase enzyme in Celiac Disease
Introduction: Celiac disease (CD) is a widespread enteropathy triggered by a diet containing cereals with gliadins in genetically predisposed individuals. Alpha-gliadin peptide 31 –43 (p31-43) is considered the main responsible of the innate immune response in CD patients and type 2 transglutaminase (TG2) enzyme is involved in CD by enhancing gliadin immunogenicity. Evidence has been reported on a role of TG2 in modulate p31-43 uptake by intestinal cells; indeed, antibodies to TG2 specifically reduced both p31-43 uptake by cells and its biological activity. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Gaetana Paolella, Marilena Lepretti, Stefania Martucciello, Lill à Lionetti, Carla Esposito, Ivana Caputo Source Type: research

Cellular and systemic analysis based on Polyunsaturated Fatty Acids protective effects against insulin- resistance condition
In this study, the protective effect was evaluated through: 1) serum parameters related to IR (HOMA index and apelin serum levels); 2) hepatic insulin signaling pathway markers (phosphorylated protein kinase B, p-Ser473-AKT/PKB); 3) endoplasmic reticulum (ER) stress marker (phosphorylated transcription factor p-eIF2α); 4) mitochondrial dynamics marker (Mitofusin 2, Mfn2). (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Ilaria Di Gregorio, Anna Busiello Rosa, Marilena Lepretti, Vincenzo Migliaccio, Lill à Lionetti Source Type: research

Effects of some nutraceuticals on the TPC1 thyroid cell line
The majority of thyroid carcinomas come from follicular cells and are defined as differentiated thyroid tumors (DTC) and the two histological subtypes are papillary CT and follicular CT. Curcumin has a wide variety of biological functions, currently, in the literature has considerable attention. The present work defines the role of curcumin on the modulation of gene expression of different cell markers and cell cycle modulation. The study was carried out using CURCUMA NATUREX and adding other nutraceuticals such as piperine and vit. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Teresa Esposito, Angelica Perna, Bruno Varriale, Antonio De Luca Source Type: research

Potential functionality of protein hydrolysates for glycaemia control
Introduction: Dietary proteins may contain some bioactive peptides (BAPs) encrypted within their primary structures. BAPs may be delivered in the food during processing and/or in the gastro-intestinal tract during food digestion and can exert some biological effects beyond nutrition such as antimicrobial, anti-thrombotic, antihypertensive, opioid and immunomodulatory effects. BAPs modulating blood glucose response are promising ingredients for functional foods development. They work through inhibition of the enzyme dipeptidyl peptidase IV (DPP-IV) that modulate glucose homeostasis by cleaving GLP-1 and GIP (Lacroix et al.,...
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Nicolina Virgilio, Paola Vitaglione Source Type: research

Plasma microRNA expression profiles are associated with early childhood obesity: Results of the I.Family Study
This study investigated the profiles of circulating miRNAs in plasma samples of normal weight (n = 159) and overweight/obese (n = 149) children participating to the I.Family study, an EC funded study finalized to investigate the etiology of overweight, obesity and related disorders in children of eight European countries (www.ifamilystudy.eu). (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Giuseppe Iacomino, Paola Russo, Pasquale Marena, Fabio Lauria, Antonella Venezia, Nunzia Iannaccone, Wolfgang Ahrens, Stefaan De Henauw, Pasquale De Luca, Ronja Foraita, Kathrin G ünther, Lauren Lissner, Dénes Molnár, Luis A Moreno, Michael Tornaritis, Source Type: research

Mediterranean, but not lacto-ovo-vegetarian, diet positively influence circulating progenitor cells for cardiovascular prevention: The cardiveg study
Introduction: Recent studies have suggested that diet may modulate the number of progenitor cells. Our aim was to evaluate the possible association between dietary habits and progenitor cells using data obtained from the CARDIVEG study, a randomized crossover trial that compared the effects of a lacto-ovo-vegetarian (VD) and a Mediterranean diet (MD). (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Giuditta Pagliai, Monica Dinu, Francesca Cesari, Angela Rogolino, Alice Sereni, Maria Anna Gori, Betti Giusti, Alessandro Casini, Rossella Marcucci, Francesco Sofi Source Type: research

Acute effects of a hallucinatory meal on subjective appetite and food intake: A randomized cross-over pilot trial
Introduction: Food intake is highly regulated by complex interactions between homeostatic and non-homeostatic mechanisms in different brain areas. Hypnosis has long been recognized as an effective tool for producing behavioral change, but his efficacy on weight reduction has received little attention. The aim of this pilot study is to assess subjective appetite and hormones involved in appetite regulation after both a hallucinatory and real meal. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Iolanda Cioffi, Roberto Gambino, Valentina Ponzo, Bice Properzi, Giuseppe Regaldo, Emanuele Triberti, Franco Contaldo, Ezio Ghigo, Fabrizio Pasanisi, Simona Bo Source Type: research

Valerolactones and healthy Ageing: Linking Dietary factors, nutrient biomarkers, metabolic status and inflammation with cognition in older adults – The VALID Project
Introduction: Several studies identified nuts, berries, cocoa, red wine and tea as preventive toward cognitive decline. These foods are rich in flavan-3-ols (F3O), among which (epi)catechin and procyanidins. However, these compounds are poorly absorbed in the upper gastro-intestinal tract and are metabolized by colonic bacteria to phenyl- γ-valerolactones (PVL), which showed biological activities and might represent better dietary exposure biomarkers compared to (epi)catechin conjugates, as they reach higher plasma Cmax and tmax. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Donato Angelino, Benjamin Paramenter, Katie Moore, Chris Gill, Pedro Mena, Alice Rosi, Eamon Laird, Adrian Moore, Michaela Black, Mary Ward, Sean Strain, Anne Marie Molloy, Daniele Del Rio, Helene McNulty Source Type: research

Chili pepper consumption and risk of total and cause-specific mortality in a Mediterranean population: Prospective findings from the Moli-sani study
Introduction: Chili pepper and its active component capsaicin have been reported to have a range of health benefits including reducing the risk of developing hypertension and obesity and also mortality risk. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Emilia Ruggiero, Augusto Di Castelnuovo, Simona Costanzo, Mariarosaria Persichillo, Amalia De Curtis, Chiara Cerletti, Maria Benedetta Donati, Giovanni de Gaetano, Licia Iacoviello, Marialaura Bonaccio Source Type: research

Food groups and risk of age-related macular degeneration: A systematic review with meta-analysis
Background: Age-related macular degeneration (AMD), a disease that causes irreversible reduction of visual function, is the leading cause of blindness in developed countries. Epidemiological studies have suggested that dietary patterns impact on AMD development and progression. Our aim was to systematically review all the prospective cohort studies available that have evaluated the consumption of different food groups and alcohol in relation to the development and progression of AMD. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Monica Dinu, Giuditta Pagliai, Alessandro Casini, Francesco Sofi Source Type: research

Relationship between Nutritional Risk Screening 2002 and Subjective Global Assessment and biochemical parameters in hospitalized patients
This study aims to evaluate how the biochemical and nutritional parameters vary according to the NRS 2002 and SGA score. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Enza Speranza, Olivia Di Vincenzo, Maurizio Marra, Carmela De Caprio, Marianna Naccarato, Gabriella Negro, Lidia Santarpia, Iolanda Cioffi, Fabrizio Pasanisi, Franco Contaldo Source Type: research

Evaluation of iodine intake compared to salt consumption in an Italian population of children and adolescents
This study analyzed the relationship between iodine intake and salt consumption in a sample of 1270 Italian children and adolescents. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Roberto Iacone, Irene Rutigliano, Pietro Formisano, Ornella Russo, Clelia Scanzano, Giuseppe Perruolo, Gianpaolo De Filippo, Angelo Campanozzi, Pasquale Strazzullo Source Type: research

Changing eating habits and evaluation of the knowledge of T2DM after meeting C-maps ™
Introduction: To date, the Mediterranean diet is the first therapeutic approach for patients with type 2 diabetes mellitus (T2DM). Conversation Maps ™ (C-Maps™) are interactive educational tools on diabetes, with a strong visual impact. The “Healthy Eating and Keeping Active” provides for a healthy eating style and physical activity in order to better handle diabetes. The aim of the study has been to evaluate the impact on changing eatin g habits and increasing the knowledge of the disease with the group therapeutic education through the use of C-Maps™ tool. (Source: Nutrition, Metabolism, and...
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Alessia Gaglio, Laura Giarratana, Eva Palmieri, Veronica Resi, Valeria Grancini, Emanuela Orsi Source Type: research

Decentralized and Mobile Monitoring of Assisted Livings' Lifestyle “use case pilot within” Interoperability of Heterogeneous IoT Platforms INTER-IoT
Introduction: The increase in the incidence of chronic degenerative diseases highlights the necessity to reorganize the network of health services. Technological innovation could reduce inequalities in access to health care by providing "tailor-made models" for citizens. The nutritional outpatient of the S. C. Hygiene of Food and Nutrition of the ASLTO5 has experimented a decentralized monitoring system thanks to the Internet of Things technology. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Marina Mortara, Anna Costa, Margherita Gulino, Massimo Uberti, Luciano Bernini, Massimo Corona, Ilaria De Luca, Monica Minutolo, Angela Dimartino, Anna Aldrighetti, Maurizia Rinaldi, Elisa Strona, Mara Gagliano, Claudio Maggi Source Type: research

Application of recursive partitioning method (RPM) to select the multi-frequency bioimpedance analysis (MF-BIA) raw parameters predicting appendicular skeletal muscle mass index (SMI)
Introduction: Anthropometric and BIA parameters are used as covariates in linear regression equation to estimate total body water and fat free mass. More recently, the research is focused on understanding the capacity of bioelectrical raw variables by itself to detect nutritional status. Objective of the study is to identify, among the multi-frequency BIA (MF-BIA) parameters, the best predictors of SMI (kg/m2) estimated by dual-energy X-ray absorptiometry (DXA). (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Alessandro Pinto, Luigi Fattorini, Lorenzo Maria Donini, Daniela Pollakova, Marco Rizzo, Lucio Gnessi, Andrea Lenzi, Camillo Cammarota Source Type: research

Salt intake and asthma in children and adolescents
Introduction: Asthma is one of the most common diseases in the world, in the last decades its prevalence has increased. Many studies have shown that excessive body weight and a high sodium intake increase the risk of asthma symptoms in children. Although the importance of diet on respiratory sensitivity is evident, the eating habits of patients with asthma are not commonly investigated in clinical practice. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Marika Dello Russo, Stefania La Grutta, Giovanna Cilluffo, Salvatore Fasola, Laura Montalbano, Giuliana Ferrante, Velia Malizia, Fabio Lauria Source Type: research

Time restricted feeding in high-level athletes: A pilot study
Introduction: Time Restricted Feeding (TRF) is an intermittent fasting model. Moro (J. Transl. Med. 2016; 14:290 ) and Tinsley (Nutr. Rev. 2015; 73:661 ) studied the effect of TRF in strength athletes and demonstrated a significant variation in body composition. Data on the effect of TRF on endurance are lacking even if preliminary data seem to suggest an improvement in muscle efficiency and a reduction in inflammation indexes. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Cinzia Ferraris, Giuseppe Marcolin, Alessandro Veneto, Anna Tagliabue, Antonio Paoli Source Type: research

Sarcopenia in renal cronic disease in conservative therapy
Introduction: Sarcopenia is a risk factor associated with chronic kidney disease (CDK). The aim of the following study was to evaluate muscle mass and its function in patients with MRC in conservative therapy. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Teresa Di Lauro, Elisabetta Salomone, Roberta Di Martino, Luigia Polese Maria, Rossella Trio, Bruna Guida Source Type: research

Correction of a patient's micronutrient status prior to sleeve gastrectomy could be useful in preventing early postoperative micronutrient deficiencies: A retrospective comparative study
Introduction: Micronutrient deficiencies (MD) after sleeve gastrectomy (SG) are frequent. Obese patients often show MD before SG. Aim of this study was to assess whether the correction of MD prior to SG plays a role in preventing early postoperative MD. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Luigi Schiavo, Vincenzo Pilone Source Type: research

Raw bioelectrical impedance (BIA) variables and physical fitness in young adults
Background: Body composition and physical fitness (PhF) are components of nutritional status closely related to each other, which can be assessed respectively using PF tests and bioelectrical impedance analysis (BIA). In particular, raw BIA variables should be evaluated because of their potential relationships with muscle strength. Of note, bioimpedance (BI) index is related to fat-free mass (FFM), while impedance ratios (IR) and phase angle (PhA) are indexes of body cell mass and extracellular/intracellular water ratio. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Paola Alicante, Ada Di Gregorio, Alessandra Manna, Lucia Bianco, Alessandra Esposito, Luca Scalfi Source Type: research

Nutritional care in the rehabilitation process of severe brain injuries: Preliminary results
Introduction: The latest ESPEN Neurological Guidelines recommend the presence in the Severe Brain Injuries (SBI) multidisciplinary rehabilitation team of a nutrition specialist who can elaborate a personalized nutritional plan and monitor it over time. The aim of this study is to evaluate the effects that an experienced Nutrition Team can have on the rehabilitation process of the patient with SBI. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Maria Luisa Eliana Luisi, Chiara Francesca Gheri, Sara Madiai, Francesca Campani, Silvia Pancani, Alessandra Consales, Barbara Biffi, Sofia Vidali, Hakiki Bahia, Carmen Di Girolamo, Claudio Macchi Source Type: research

The assessment of nutrition status with the mini nutritional assessment (mna) in patients with chronic-ostructive pulmunary disease (COPD)
Introduction: Chronic obstructive pulmonary disease (COPD) is a chronic disease with a high prevalence of malnutrition. There are a few data in the literature on the use of Mini Nutritional Assessment (MNA) in COPD patients. MNA is a widely used tool for assessing nutritional status in the elderly. Aim of the study is to identify the prevalence of malnutrition in COPD patients using MNA and evaluate the relationships between MNA and body composition (bioelectrical impedance analysis = BIA). (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Ada Di Gregorio, Paola Alicante, Francesca De Blasio, Alessandra Esposito, Francesco De Blasio, Alessandra De Chiara, Luca Scalfi Source Type: research

Impact of mediterranean vs vegetarian diets on gut microbiota and short chain fatty acids: The CARDIVEG study
Introduction: There is a growing interest in understanding how diet can modulate the intestinal microbiota, including its possible associations with diseases. The aim of the present project is to compare in a group of patients in primary prevention for cardiovascular disease (CV) the effects of Mediterranean (MD) and Vegetarian (VD) dietary patterns on the composition of the gut microbiota and on the production of short-chain fatty acids (SCFA). (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Giuditta Pagliai, Edda Russo, Simone Baldi, Monica Dinu, Gianluca Bartolucci, Elena Niccolai, Giulia Nannini, Alessandro Casini, Amedeo Amedei, Francesco Sofi Source Type: research

Non-linear (J-shaped) association of alcohol intake with total mortality: Results from the MORGAM project
Introduction: Alcohol intake has a monotonic detrimental role for several diseases (in particular some cancers), but is associated with reduced risk of ischemic heart disease when consumed in moderation. The association of moderate alcohol intake with total mortality remains controversial. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Augusto Di Castelnuovo, Simona Costanzo, Marialaura Bonaccio, Patrick McElduff, Allan Linneberg, Veikko Salomaa, Satu M ännistö, Marie Moitry, Jean Ferrières, Jean Dallongeville, Barbara Thorand, Hermann Brenner, Marco Ferrario, Abdonas Tamosiunas, Ing Source Type: research

Biomarkers of intake of a Mediterranean Diet: Which contribution from the gut microbiota?
Introduction: Observational studies indicate that the adherence to a Mediterranean diet is inversely associated with the incidence of some noncommunicable chronic diseases. The effect may be mediated by the gut microbiota that can influence the etiopathogenetic mechanisms through some metabolites active at colon and/or systemic level. On the frame of the DINAMIC project the objective of this study is to shade light on the biomarkers of Mediterranean diet in association with the composition of gut microbiota. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Paola Vitaglione, Angela Albarosa Rivellese, Danilo Ercolini, Marilena Vitale, Rosalba Giacco, Francesca De Filippis, Ilario Mennella Source Type: research

Relationship between adherence to a Mediterranean Dietary Pattern and cardiometabolic risk factors profile in People with Type 2 Diabetes
Introduction: To analyze the relationship between adherence to the Mediterranean diet, glucose control, body weight and major cardiovascular (CV) risk factors in people with type 2 diabetes mellitus (T2DM) and to evaluate the impact thereon of specific foods, typical of this dietary pattern. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Ilaria Calabrese, Marilena Vitale, Maria Masulli, Angela Albarosa Rivellese, Gabriele Riccardi, Olga Vaccaro Source Type: research

Interaction between Mediterranean diet and statins on mortality risk in patients with cardiovascular disease: Prospective findings from the Moli-sani Study
Introduction: Statins are prescribed for patients with cardiovascular disease (CVD), along with the recommendation of adopting healthy diets. This stufy aimed to evaluate the independent and the combined effect of statins and Mediterranean diet (MD) towards mortality risk in subjects with previous CVD by using real-life data from a population-based prospective cohort. We performed a longitudinal analysis on 1,180 subjects (mean age 67.7 ± 10) with prior CVD at enrollment in the Moli-sani study and followed up for 7.9 years (median). (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Marialaura Bonaccio, Augusto Di Castelnuovo, Simona Costanzo, Mariarosaria Persichillo, Amalia De Curtis, Chiara Cerletti, Maria Benedetta Donati, Giovanni De Gaetano, Licia Iacoviello Source Type: research

Impact of the ketogenic diet on human gut
Background: The classic ketogenic diet (KD) is an normocaloric dietary protocol with a high intake of fats (85 –90% of energy), which is used as a therapy for drug-resistant epilepsies and type 1 glucose transporter deficiency syndromes (GLUT1-DS). It is known that specific dietetic patterns can influence the composition of the intestinal microbiota; in particular, it was shown that KD is associated with v arious pro-inflammatory changes in the microbiota. Aim of the study is to verify the impact of KD on the intestinal microbiota, through the evaluation of: intestinal bacterial composition, markers of bacterial meta...
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Erika Meroni, Cinzia Ferraris, Anna Tagliabue, Elisa Borghi, Francesca Borgo, Giulia Bassanini, Camilla Ceccarani, Maria Cristina Casiraghi, Daniela Erba Source Type: research

Dietary intervention with vegetarian and mediterranean diets for cardiovascular prevention: Effects on hormones involved in the energy balance
Background: First line treatment for obesity consists of improvement of dietary habits. Vegetarian (VD) and Mediterranean (MD) diets are reported as two of the healthiest diets. Our aim was to compare the effects of VD and MD on hormones involved in the energy balance, using data from the CARDIVEG study, a randomized dietary intervention trial. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Monica Dinu, Giuditta Pagliai, Barbara Colombini, Alice Sereni, Anna Maria Gori, Betti Giusti, Rossella Marcucci, Alessandro Casini, Francesco Sofi Source Type: research

Adherence to Mediterranean Diet and Quality of Life in women treated for breast cancer (DEDiCa Study)
Introduction: Several lines of evidence confirm the role of the Mediterranean Diet (MedD) on primary and secondary prevention of chronic disease, such as diabetes, cardiovascular disease and cancer. Health-Related Quality of Life (HRQOL) includes physical, mental, emotional and social factors. A few studies evaluated the impact of the MedD on HRQOL. Therefore, we investigated the possible effect of adherence to the MedD on HRQOL in the DEDiCa Study (NCT02786875) participants, a study that evaluates the combined effect of diet, physical activity and vitamin D on the risk of recurrence in women diagnosed with breast cancer. ...
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Giuseppe Porciello, Ilaria Calabrese, Concetta Montagnese, Sara Vitale, Elvira Palumbo, Serena Cubisino, Luca Falzone, Anna Crispo, Maria Grimaldi, Massimo Libra, Rosita Pica, Michele De Laurentis, Ernesta Cavalcanti, Massimiliano D'Aiuto, Massimo Rinaldo Source Type: research

Different effect of a period of caloric restriction following treatment with a normal lipid or hyperlipidic diet in the experimental animal model: Focus on mitochondrial dynamics proteins in the liver
Introduction: An excess of the daily caloric intake facilitates accumulations of fat that leads to the development of obesity. Caloric restriction is the strategy used to restore body composition to optimal levels. Likewise, a period of hypo-nutrition following a balanced diet promotes nutritional deficiencies. Both conditions above described induce changes in the cellular metabolism to which the mitochondria actively participate. These organelles are very dynamic and undergo against continuous fusion and fission processes in correlation with their functionality. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Vincenzo Migliaccio, Raffaella Sica, Marilena Lepretti, Rosaria Scudiero, Rosalba Putti, Lill à Lionetti Source Type: research

Food waste and children's preferences towards vegetables in primary schools: Two Italian case studies
Introduction: The food waste analysis in the school canteen context is particularly relevant due to its educational and environmental relevance, the huge number of users and the consequent food amount handled every day. The present study, carried out within the EU H2020-funded Strength2food project, seeks to compare two case studies (Parma vs Lucca), characterised by different primary school food procurement models (local-organic vs organic) in relation to (i) the uneaten edible food served in primary school canteens and (ii) children ’s refusal towards the vegetable side dish. (Source: Nutrition, Metabolism, and Car...
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Beatrice Biasini, Alice Rosi, Francesca Giopp, Michele Donati, Filippo Arfini, Francesca Scazzina Source Type: research

Effects of a 3-months' dietary intervention with lacto-ovo-vegetarian diet on vitamin B12 levels: Results of the CARDIVEG study
Introduction: Previous studies have suggested that following a lacto-ovo-vegetarian diet (VD) may increase the risk of vitamin B12 deficiency. Our aim was to investigate whether VD followed for 3 months by omnivores could lead to decrease of circulating vitamin B12 levels. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Monica Dinu, Giuditta Pagliai, Francesca Cesari, Alice Sereni, Betti Giusti, Anna Maria Gori, Rossella Marcucci, Alessandro Casini, Francesco Sofi Source Type: research

Association of traditional Mediterranean diet and non-Mediterranean dietary scores with all-cause and cause-specific mortality: Prospective findings from the Moli-sani study
Introduction: Health benefits associated with Mediterranean diet (MD) are well-established in non-Mediterranean population settings, while less is known on the potential health advantages associated with non-Mediterranean dietary (MD) patterns among Mediterranean populations. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Marialaura Bonaccio, Augusto Di Castelnuovo, Simona Costanzo, Mariarosaria Persichillo, Amalia De Curtis, Chiara Cerletti, Maria Benedetta Donati, Giovanni De Gaetano, Licia Iacoviello Source Type: research

Effect of a low glycemic index Mediterranean diet on cardiovascular risk factors in women diagnosed with breast cancer: Preliminary data from DEDiCa study
Introduction: Life expectancy in women with breast cancer (BC) is 80% at 5 years. Age, medications, obesity, metabolic syndrome and diabetes increase cardiovascular risk. The Mediterranean diet (MeD) and low glycemic index (GI) diets, nevertheless, are protective. Therefore, we evaluated the effect of low-GI Mediterranean diet on cardiovascular risk factors in women treated for BC. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Ilaria Calabrese, Giuseppe Porciello, Concetta Montagnese, Sara Vitale, Elvira Palumbo, Serena Cubisino, Anna Crispo, Maria Grimaldi, Rosita Pica, Vincenzo Marotta, Luca Falzone, Patrizia Dainotta, Michele De Laurentis, Massimiliano D'Aiuto, Massimo Rinal Source Type: research

Observational study on adolescents ’ lifestyle of Parma: Adherence to Mediterranean diet, physical activity and time and quality of sleep
Introduction: Diet, physical activity and sleep are potential risk factors for overweight and obesity and could influence the proper growth during the developmental age. Therefore, monitoring adolescents ’ lifestyle is essential to better understand the association between body composition and possible risk behavioural variables and to design preventive programme for educating people towards healthy habits. Thus, the aim of the study was to investigate the relations between BMI and lifestyle facto rs in a sample of Italian adolescents. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Francesca Giopp, Alice Rosi, Francesca Scazzina Source Type: research

Food database of endocannabinoids, N-acylethanolamines and N-acylphosphatidylethanolamines and daily intake in Western, Mediterranean and Vegetarian diets
Introduction: N-acylphosphatidylethanolamines (NAPEs), N-acylethanolamines (NAEs), and the endocannabinoids (ECs) are lipids involved in different physiological processes in both animals and plants. NAEs derive from NAPEs through the action of NAPE-PLD. NAEs can be hydrolyzed by FAAH and form free fatty acids and ethanolamine. In animals, NAEs and ECs activate the cannabinoids receptors, the vanilloid receptor/TRPV1, peroxisome proliferator-activated receptor- α (PPAR-α) and G protein-coupled receptors present along the gastrointestinal tract (GIT). (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Lucia De Luca, Paola Vitaglione Source Type: research

Long-term effects of the ketogenic diet on growth in children with resistant drug epilepsy and Glucose Transporter Type 1 Deficiency Syndrome
Introduction: The ketogenic diet (KD) is an effective therapeutic option for patients with drug-resistant epilepsy (EFR) and is the only therapy currently available for Glucose Transporter Type 1 Deficiency Syndrome (GLUT1-DS). Studies on long-term effects and, particularly, on growth are required. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Cinzia Ferraris, Valentina De Giorgis, Ilaria Brambilla, Monica Guglielmetti, Claudia Trentani, Lara Manea, Ottavia Ferraro, Simona Bertoli, Pierangelo Veggiotti, Anna Tagliabue Source Type: research

Support of nutritional therapy in the koreic syndrome: Clinical case
Introduction: The choreic syndrome is characterized by irregular, arrhythmic movements, variable location, difficulty in phonation and deglutition and increase in energy expenditure. The aim of the study was to evaluate the weight variation and body composition during nutritional therapy. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Maria Luigia Polese, Roberta Di Martino, Teresa Di Lauro, Elisabetta Salomone, Rossella Trio, Bruna Guida Source Type: research

Body density estimation from multi-frequency Bioelectrical Impedance Analysis measurements
The objectives of the study is to define the relationship between Bioelectrical parameters obtained by Multifrequency Biolectrical Analysis (MF-BIA) and D. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Luigi Fattorini, Aurora Summa, Enrico Marchetti, Stefania Corradi, Jonathan di Fazio, Claudia Fantini, Lorenzo Maria Donini, Camillo Cammarota, Alessandro Pinto Source Type: research

Bioelectrical impedance analysis (BIA) and physical fitness in nephropathic patients on peritoneal dialysis
Introduction: Body composition and physical fitness are both components of nutritional status and are closely related to each other. In clinical practice, they can be assessed using bioelectrical impedance analysis (BIA) and performing physical fitness tests (PF), respectively. The main objective of the study was to evaluate in patients in peritoneal dialysis (PD) the relationships of PF tests with those BIA variables that are considered as markers of skeletal muscle quality (qualitative BIA). (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Authors: Ada Di Gregorio, Silvia Migliaccio, Carmela Legorano, Gennaro Argentino, Domenico Russo, Luca Scalfi Source Type: research

Editorial Board
(Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 20, 2019 Category: Nutrition Source Type: research