Identification of biomarkers for essential hypertension based on metabolomics
Essential hypertension (EH) is one of the most important public health problems worldwide. However, the pathogenesis of EH is unclear and early diagnostic methods are lacking. Metabolomics demonstrates great potential for biomarker discovery and mechanistic exploration of metabolic diseases. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - December 2, 2020 Category: Nutrition Authors: Yueting Deng, Chen Huang, Jingyue Su, Chen-Wei Pan, Chaofu Ke Tags: Systematic Reviews and Meta-analyses Source Type: research

Comparison of Different Obesity Indices related with Hypertension among Different Sex and Age groups in China
To compare the relationships of five obesity-related routine anthropometric indicators (body mass index (BMI), BAI, body adiposity index (BAI), waist circumference (WC), waist-to-hip ratio, waist-to-height ratio (WHtR)) for hypertension in both sexes and among different age groups of the Chinese population. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - December 1, 2020 Category: Nutrition Authors: Qiwei Ge, Zhigang Qi, Zhengcheng Xu, Min Li, Huiyan Zheng, Xiaoyang Duan, Minjie Chu, Xun Zhuang Source Type: research

Relationships between diet and basal fat oxidation and maximal fat oxidation during exercise in sedentary adults
To study the relationships between different dietary factors (i.e., energy, macronutrient and fatty acid intake, food group consumption, and dietary pattern) and basal fat oxidation (BFox) and maximal fat oxidation during exercise (MFO) in sedentary adults. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - December 1, 2020 Category: Nutrition Authors: Lucas Jurado-Fasoli, Francisco J. Amaro-Gahete, Elisa Merchan-Ramirez, Idoia Labayen, Jonatan R. Ruiz Source Type: research

Association of plasma fatty acids pattern with omentin gene expression in human adipose tissues: A cross-sectional study
Omentin, as an adipokine, has been reported to improve insulin resistance and inflammation may be related to fatty acids (FAs). Plasma FAs can be used as biomarkers of dietary FAs and endogenous FA exposure. We aimed to evaluate the association between plasma FAs pattern and omentin gene expression in adipose tissue (AT). (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 27, 2020 Category: Nutrition Authors: Mohammad Nosrati-Oskouie, Emad Yuzbashian, Maryam Zarkesh, Nazanin sadat Aghili-Moghadam, Mehdi Hedayati, Mohammad Safarian, Golaleh Asghari, Alireza Khalaj, Parvin Mirmiran Source Type: research

Effects of virgin coconut oil consumption on metabolic syndrome components and asymmetric dimethylarginine: a randomized controlled clinical trial
This study aimed to assess the effects of virgin coconut oil (VCO) consumption on metabolic syndrome (MetS) components, as well as, asymmetric dimethylarginine (ADMA) in adults with MetS. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 27, 2020 Category: Nutrition Authors: Parinaz Nikooei, Mohammad Javad Hosseinzadeh-Attar, Somayyeh Asghari, Abdolreza Norouzy, Mehdi Yaseri, Ali Vasheghani-Farahani Source Type: research

Elevated serum uric acid and risk of cardiovascular or all-cause mortality in maintenance hemodialysis patients: a meta-analysis
Studies have shown inconsistent results about the association between serum uric acid (SUA) levels and mortality in hemodialysis patients. We performed this meta-analysis to determine whether higher SUA values comprised a risk factor of cardiovascular or all-cause mortality in maintenance hemodialysis patients. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 25, 2020 Category: Nutrition Authors: Huifang Wang, Jun Liu, Demin Xie, Hang Liu, Li Zhen, DanDan Guo, Xuemei Liu Tags: Systematic Reviews and Meta-analyses Source Type: research

Protein intake is not associated with functional biomarkers of physical frailty: a cross-sectional analysis of community-dwelling older adults with type 2 diabetes mellitus
Frailty has emerged as a third category of complication in patients with type 2 diabetes mellitus (T2DM). It has been suggested that adequate protein intake is an important dietary strategy for counteracting frailty. Therefore, we explored the association between protein intake and functional biomarkers of frailty in older adults with T2DM. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 24, 2020 Category: Nutrition Authors: Anthony Villani, Michelle Barrett, Rebecca McClure, Hattie Wright Source Type: research

Trend in potassium intake and Na/K ratio in the Italian adult population between the 2008 and 2018 CUORE Project surveys
Low potassium intake, in addition to high sodium, has been associated with higher risk of hypertension and CVD. The Study assessed habitual potassium intake and sodium/potassium ratio of the Italian adult population from 2008-2012 to 2018-2019 based on 24-hour urine collection, in the framework of the CUORE Project/MINISAL-GIRCSI/MENO SALE PIU ’ SALUTE national surveys. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 23, 2020 Category: Nutrition Authors: Chiara Donfrancesco, Cinzia Lo Noce, Ornella Russo, Brigitta Buttari, Elisabetta Profumo, Daniela Minutoli, Anna Di Lonardo, Roberto Iacone, Francesca Vespasiano, Serena Vannucchi, Graziano Onder, Ferruccio Galletti, Daniela Galeone, Paolo Bellisario, And Source Type: research

Sweetener influences plasma concentration of flavonoids in humans after an acute intake of a new (poly)phenol-rich beverage
The overconsumption of sucrose is closely related to sugar-sweetened beverages and one of the main factors associated with the increase of metabolic diseases, such as type 2 diabetes, obesity, and insulin resistance. So, the addition of alternative sweeteners to new fruit-based drinks could contribute to minimizing the incidence or severity of these pathologies. Nevertheless, current knowledge on the influence of these additives on the bioactive compounds present in these beverages is still scarce. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 23, 2020 Category: Nutrition Authors: Vicente Agull ó, Raúl Domínguez-Perles, Cristina García-Viguera Source Type: research

Editorial Board
(Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 21, 2020 Category: Nutrition Source Type: research

Soluble ST2 proteins in male cachectic patients with chronic heart failure
Until now, there are lack of established clinical factors allowing management of chronic heart failure (CHF) patients being at risk of cardiac cachexia (CC). The changes in soluble protein ST2 (sST2) concentrations suggest a valuable and prognostic usefulness of this biomarker in monitoring patients with CHF, especially those who potentially are prompt to develop CC. The aim of this study was to assess the potential role of sST2 in male patients with CHF under cachexia condition. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 20, 2020 Category: Nutrition Authors: Grzegorz Sobieszek, Tomasz Powr ózek, Andrzej Jaroszyński, Aneta Skwarek-Dziekanowska, Mansur Rahnama-Hezavah, Teresa Małecka-Massalska Source Type: research

Early-life exposure to the Chinese famine and risk of carotid intima-media thickness increased in adulthood
Little was known about the effect of famine exposure on carotid intima-media thickness (cIMT). The present study aimed to explore the relationship in a Chinese population. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 20, 2020 Category: Nutrition Authors: Lin Liu, Yu-qing Huang, Kenneth Lo, Chao-lei Chen, Jie Li, Ying-qing Feng Source Type: research

PCSK9 levels do not predict severity and recurrence of cardiovascular events in patients with acute myocardial infarction
It remains unclear whether serum PCSK9 levels can predict the severity of the disease and the risk of future events in patients with coronary artery disease (CAD). We aimed to evaluate the association between PCSK9 levels, metabolic parameters, severity of CAD on coronary angiography (SYNTAX score), and the risk of in-hospital events and at one-year follow-up. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 20, 2020 Category: Nutrition Authors: Marianne Zeller, Gilles Lambert, Michel Farnier, Maud Maza, Brice Nativel, Luc Rochette, Catherine Vergely, Yves Cottin Source Type: research

Metabolic syndrome is related to vascular structural alterations but not to functional one both in hypertensives and healthy subjects
Metabolic Syndrome (MS) has been related to an impairment in arterial structural and functional properties with heterogeneous results. In this paper we focused on the effects of MS on arterial carotid-femoral PWV and common carotid IMT in two different populations, one of hypertensive patients and one of healthy controls. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 19, 2020 Category: Nutrition Authors: Alessandro Maloberti, Michele Bombelli, Paola Vallerio, Martina Milani, Iside Cartella, Giovanni Tavecchia, Chiara Tognola, Enzo Grasso, Jinwei Sun, Benedetta De Chiara, Salvatore Riccobono, Guido Grassi, Cristina Giannattasio Source Type: research

Obesity as a risk factor for unfavourable outcomes in critically ill patients affected by Covid 19
Recent studies show that obesity is a risk factor for hospital admission and for critical care need in patients with coronavirus disease 2019 (COVID-19). The aim was to determine whether obesity is a risk factor for unfavourable health outcomes in patients affected by COVID-19 admitted to ICU. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 19, 2020 Category: Nutrition Authors: Andrea P. Rossi, Leonardo Gottin, Katia Donadello, Vittorio Schweiger, Riccardo Nocini, Matteo Taiana, Mauro Zamboni, Enrico Polati Source Type: research

Undernutrition in childhood and adolescence and atherosclerosis in adult life
(Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 19, 2020 Category: Nutrition Authors: Carmine Zoccali, Francesca Mallamaci Tags: Commentary Source Type: research

Apolipoprotein A5 controls fructose-induced metabolic dysregulation in mice
Western dietary habits are partially characterized by increased uptake of fructose, which contributes to metabolic dysregulation and associated liver diseases. For example, a diet enriched with fructose drives insulin resistance and non-alcoholic fatty liver disease (NAFLD). The molecular hubs that control fructose-induced metabolic dysregulation are poorly understood. Apolipoprotein A5 (apoA5) controls triglyceride metabolism with a putative role in hepatic lipid deposition. We explored apoA5 as a rheostat for fructose-induced hepatic and metabolic disease in mammals. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 16, 2020 Category: Nutrition Authors: Claudia Ress, Jochen Dobner, Kerstin Rufinatscha, Bart Staels, Maximilian Hofer, Sabrina Folie, Bernhard Radlinger, Timon E. Adolph, Eduard M. Rubin, Michael Roden, Herbert Tilg, Susanne Kaser Source Type: research

Association between serum netrin-1 and prognosis of ischemic stroke: the role of lipid component levels
High serum netrin-1 levels decrease the risk of ischemic stroke and are negatively associated with outcomes after ischemic stroke. However, it remains unclear whether the association between netrin-1 and ischemic stroke prognosis is modified by lipid component levels. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 13, 2020 Category: Nutrition Authors: Yuhan Zang, Daoxia Guo, Lihua Chen, Pinni Yang, Zhengbao Zhu, Xiaoqing Bu, Tian Xu, Chongke Zhong, Aili Wang, Hao Peng, Tan Xu, Jing Chen, Yonghong Zhang, Jiang He Source Type: research

Association Of Adipocytokines Serum Levels With Left Atrial Thrombus Formation In Atrial Fibrillation Patients On Oral Anticoagulation (Alert) – A Cross-Sectional Study
Oral anticoagulation is effective for stroke prevention in atrial fibrillation (AF). However, strokes may still occur in high-risk individuals. We conducted a prospective trial to assess the association between adipocytokine serum levels and surrogate parameters for thromboembolic events. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 13, 2020 Category: Nutrition Authors: Hermann Blessberger, Patrick Mueller, Hisaki Makimoto, Friederike Hauffe, Anita Meissner, Christopher Gemein, Joern Schmitt, Christian Hamm, Thomas Deneke, Fabian Schiedat, Andreas M ügge, Michael Gabriel, Clemens Steinwender Source Type: research

Analysis of steatosis biomarkers and inflammatory profile after adding on PCSK9 inhibitor treatment in familial hypercholesterolemia subjects with nonalcoholic fatty liver disease: a single lipid center real-world experience
Nonalcoholic fatty liver disease (NAFLD) may be crucial in subjects with familial hypercholesterolemia (FH). We aimed to evaluate the effect of the inhibitors of proprotein convertase subtilisin/kexin type 9 (PCSK9-i) on steatosis biomarkers such as triglyceride-glucose index (TyG) and hepatic steatosis index (HSI) and analyse the role of TG/HDL in this population before and after adding-on PCSK9-i. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 13, 2020 Category: Nutrition Authors: Roberto Scicali, Antonino Di Pino, Francesca Urbano, Viviana Ferrara, Simona Marchisello, Stefania Di Mauro, Alessandra Scamporrino, Agnese Filippello, Agata Maria Rabuazzo, Francesco Purrello, Salvatore Piro Source Type: research

Effect of caloric restriction with or without physical activity on body composition and epicardial fat in type 2 diabetic patients: a pilot randomized controlled trial
There is debate over the independent and combined effects of caloric restriction (CR) and physical activity (PA) on reduction in fat mass and in epicardial fat thickness. We compared the impact of a similar energy deficit prescription by CR or by CR combined with PA on total fat mass, epicardial fat thickness, and cardiometabolic profile in individuals with type 2 diabetes. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 12, 2020 Category: Nutrition Authors: Jos ée Leroux-Stewart, Belinda Elisha, Sémah Tagougui, Corinne Suppère, Sophie Bernard, Hortensia Mircescu, Katherine Desjardin, Virginie Messier, Gianluca Iacobellis, Rémi Rabasa-Lhoret Source Type: research

Suppression of serum lipid transfer proteins involved in high-density lipoprotein cholesterol metabolism by intensive insulin therapy in the first year of type 1 diabetes: Prospective InLipoDiab1 Study
Cholesteryl ester transfer protein (CETP) and phospholipid transfer protein (PLTP) are crucial proteins in reverse cholesterol transport. There are insufficient data on regulating these proteins by insulin therapy in type 1 diabetes (T1DM). We aimed to assess prospectively the impact of insulin therapy initiation on transfer proteins serum levels in adults with newly diagnosed T1DM. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 12, 2020 Category: Nutrition Authors: Aleksandra Cieluch, Aleksandra Uruska, Marcin Nowicki, Ewa Wysocka, Agata Grzelka-Wo źniak, Justyna Flotyńska, Paweł Niedźwiecki, Dorota Zozulinska-Ziolkiewicz Source Type: research

Short duration of sleep and incidence of overweight or obesity in Chinese children and adolescents: a systematic review and meta-analysis of prospective studies
Overweight and obesity in children have become a global public health problem. Epidemiological studies suggest that sleep duration may contribute to the incidence of overweight and obesity in all stages of life. China has an increasing prevalence of overweight and obesity, and sleep deprivation is common among Chinese children. The aim of this study was to assess the prospective relationship between short sleep duration and overweight or obesity in Chinese children and to gain an estimate of the risk. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 11, 2020 Category: Nutrition Authors: Yuan Guo, Michelle A. Miller, Francesco P. Cappuccio Tags: Systematic Reviews and Meta-analyses Source Type: research

Abdominal Aortic Calcification is Associated with Decline in Handgrip Strength in the U.S. Adult Population ≥40 Years of Age
The present study investigated the association between abdominal aortic calcification(AAC) and handgrip strength(HGS) and the ability of HGS to predict an increased AAC phenotype in adults. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 11, 2020 Category: Nutrition Authors: Robinson Ram írez-Vélez, Antonio García-Hermoso, María Correa-Rodríguez, Felipe Lobelo, Katherine González-Ruiz, Mikel Izquierdo Source Type: research

Cardiovascular health behaviors and associations of sex, age, and education in adolescents - results from the EVA Tyrol Study
Ideal cardiovascular health (CVH) behaviors in adolescents are defined by body mass index (BMI), diet, physical activity and smoking, and are directly associated with better health in later life. To further improve health prevention programs we investigated the prevalence of these behaviors in a cohort of healthy adolescents and focused on the associations with sex, age, and education. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 9, 2020 Category: Nutrition Authors: Nina Gande, Raimund Pechlaner, Beno ît Bernar, Anna Staudt, Katharina Stock, Christoph Hochmayr, Ralf Geiger, Ursula Kiechl-Kohlendorfer, Michael Knoflach, for the Early Vascular Aging (EVA) Study Group Source Type: research

Obesity Measures at Baseline, Their Trajectories Over Time, and the Incidence of Chronic Kidney Disease: A 14 year Cohort Study Among Korean Adults
We investigated the association of baseline obesity measures, i.e. body mass index (BMI), waist circumference (WC), hip circumference (HC), and waist-hip ratio (WHR), and their trajectories over time with incident chronic kidney disease (CKD). (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 4, 2020 Category: Nutrition Authors: Hyun-Soo Zhang, Seokyung An, Choonghyun Ahn, Sue K. Park, Boyoung Park Source Type: research

The loss-of-function mutation of CETP affects HDLc levels but not ApoA1 in patients with acute myocardial infarction
Loss of the cholesteryl ester transfer protein (CETP) function affects HDLc levels, but its effects on major HDL protein component ApoA1 are not well understood in patients with acute myocardial infarction (AMI). (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 2, 2020 Category: Nutrition Authors: Weiping Li, Xin Liu, Chunyi Huang, Liusheng Liu, Xuerui Tan, Xingyu Wang Tags: Review Source Type: research

Elevated serum uric acid is associated with a greater inflammatory response and with short- and long-term mortality in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention
This study sought to investigate the association between eSUA with short- and long-term mortality and with inflammatory response in patients with STEMI treated with primary percutaneous coronary intervention (pPCI). (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 2, 2020 Category: Nutrition Authors: Alessandro Mandurino-Mirizzi, Stefano Cornara, Alberto Somaschini, Andrea Demarchi, Marco Galazzi, Sebastiano Puccio, Claudio Montalto, Gabriele Crimi, Marco Ferlini, Rita Camporotondo, Massimiliano Gnecchi, Maurizio Ferrario, Luigi Oltrona Visconti, Gaet Source Type: research

Does the weight loss efficacy of alternate day fasting differ according to sex and menopausal status?
This study examined if the weight loss and metabolic benefits of alternate day fasting (ADF) varies according to sex and menopausal status in adults with obesity. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 30, 2020 Category: Nutrition Authors: Shuhao Lin, Manoela Lima Oliveira, Kelsey Gabel, Faiza Kalam, Sofia Cienfuegos, Mark Ezpeleta, Surabhi Bhutani, Krista A. Varady Source Type: research

Trend of salt intake measured by 24-h urine collection in the Italian adult population between the 2008 and 2018 CUORE Project surveys
The WHO Global Action Plan for the Prevention of NCDs recommends a 30% relative reduction in mean population salt/sodium intake. The Study assessed the trend in the habitual salt intake of the Italian adult population from 2008-2012 to 2018-2019 based on 24-hour urinary sodium excretion, in the framework of the CUORE Project/MINISAL-GIRCSI/MENO SALE PIU ’ SALUTE national surveys. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 30, 2020 Category: Nutrition Authors: Chiara Donfrancesco, Cinzia Lo Noce, Ornella Russo, Daniela Minutoli, Anna Di Lonardo, Elisabetta Profumo, Brigitta Buttari, Roberto Iacone, Francesca Vespasiano, Serena Vannucchi, Graziano Onder, Ferruccio Galletti, Daniela Galeone, Paolo Bellisario, Mic Source Type: research

Skin carotenoids status as a potential surrogate marker for cardiovascular disease risk determination in middle-aged and older adults
This study aimed to assess the associations between dietary, plasma and skin carotenoids with CVD risk indicators and examine the mediational role of plasma carotenoids in the relationship between skin carotenoids status (SCS) and CVD risk. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 26, 2020 Category: Nutrition Authors: Darel Wee Kiat Toh, Clarinda Nataria Sutanto, Wen Wei Loh, Wan Yee Lee, Yuanhang Yao, Choon Nam Ong, Jung Eun Kim Source Type: research

Real-Life Appraisal On Blood Pressure Targets Achievement In Adult Outpatients At High Cardiovascular Risk
Although hypertension guidelines highlight the benefits of achieving the recommended blood pressure (BP) targets, hypertension control rate is still insufficient, mostly in high or very high cardiovascular (CV) risk patients. Thus, we aimed to estimate BP control in a cohort of patients at high CV risk both primary and secondary prevention. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 24, 2020 Category: Nutrition Authors: Vivianne Presta, Barbara Citoni, Ilaria Figliuzzi, Simona Marchitti, Andrea Ferrucci, Massimo Volpe, Giuliano Tocci Source Type: research

Editorial Board
(Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 21, 2020 Category: Nutrition Source Type: research

COVID-19 disease and nutritional choices: how will the pandemic reconfigure our food psychology and habits? A case study of the Italian population
In Italy, the spread of the novel coronavirus (SARS-Cov-2) required lifestyle changes that have affected food choices and people ’s health condition. We explore people’s perception of the role of food consumption as a preventive measure and how it reconfigures consumption habits. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 21, 2020 Category: Nutrition Authors: Mariarosaria Savarese, Greta Castellini, Lorenzo Morelli, Guendalina Graffigna Tags: Short Communication Source Type: research

Lipid levels and the risk of hemorrhagic stroke: A dose –response meta-analysis
Hemorrhagic stroke (HS) could damage human health and impose heavy social and economic burden around the world. An accumulating number of studies revealed the effect of lipid levels on HS, whereas the results were inconsistent. Therefore, we conducted a dose –response meta-analysis to evaluate the relationship between lipid levels and HS. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 20, 2020 Category: Nutrition Authors: Xiaolin Jin, Hanze Chen, Han Shi, Kailei Fu, Jinwei Li, Li Tian, Weiyu Teng Tags: Systematic Reviews and Meta-analyses Source Type: research

No Causal Association Between Plasma Homocysteine Levels and Atrial Fibrillation: A Mendelian Randomization Study
Although several studies have shown an association between plasma homocysteine (Hcy) levels and atrial fibrillation (AF), the causality remains unclear. We undertook a Mendelian randomization (MR) study to investigate the causal association between Hcy and AF. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 20, 2020 Category: Nutrition Authors: Xingang Sun, Yunlong Lu, Zhen Wang, Qiqi Wang, Liangrong Zheng Source Type: research

Lipid levels and the risk of hemorrhagic stroke: A dose-response meta-analysis
Hemorrhagic stroke (HS) could damage human health and impose heavy social and economic burden around the world. An accumulating number of studies revealed the effect of lipid levels on HS, whereas the results were inconsistent. Therefore, we conducted a dose-response meta-analysis to evaluate the relationship between lipid levels and HS. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 20, 2020 Category: Nutrition Authors: Xiaolin Jin, Hanze Chen, Han Shi, Kailei Fu, Jinwei Li, Li Tian, Weiyu Teng Tags: Systematic Reviews and Meta-analyses Source Type: research

Authors ’ response to letter by Sbrana et al. “Evolocumab improve intima media thickness regression in He-FH subjects on lipoprotein apheresis”
We appreciated the comments by Sbrana et  al. [1] about our study [2] and we read with interest their results on atherosclerosis regression in subjects with familial hypercholesterolemia (FH) undergoing a combined treatment with lipoprotein apheresis (LA) and evolocumab. FH subjects are known to exhibit early atherosclerosis development a nd progression [3,4]. A wealth of evidence showed the impact of PCSK9 inhibitors (PCSK9–I) on atherosclerosis regression, being this an important therapeutic achievement, with relevant clinical impact on cardiovascular morbidity and mortality, mainly in FH subjects [5–9]....
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 19, 2020 Category: Nutrition Authors: Ilenia Calcaterra, Alessio Buonaiuto, Gabriella Iannuzzo, Matteo N.D. Di Minno Tags: Letter to the Editor Source Type: research

Authors ’ response to letter by Sbrana et al. “Evolocumab improve intima media thickness regression in He-FH subjects on lipoprotein apheresis”
(Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 19, 2020 Category: Nutrition Authors: Ilenia Calcaterra, Alessio Buonaiuto, Gabriella Iannuzzo, Matteo Nicola Dario Di Minno Tags: Letter to the Editor Source Type: research

Differentially expressed miR-152, a potential biomarker for in-stent restenosis (ISR) in peripheral blood mononuclear cells (PBMCs) of coronary artery disease (CAD) patients
ISR remains the most daunting challenge of current treatments of CAD. MicroRNAs (miRNAs) are prominent regulators of key pathological processes leading to restenosis are being used as diagnostic tools in different studies. miR-152 and miR-148a are implicated to contribute in the putative intracellular mechanisms of ISR. The aim of present study was to investigate the potential early stage diagnostic role of miR-152 and miR-148a expression levels for ISR in PBMCs of patients underwent stent implantation. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 19, 2020 Category: Nutrition Authors: M. Maheronnaghsh, I. Niktab, S. Enayati, Mahsa M. Amoli, S.K. Hosseini, Bazzaz J. Tavakkoly Source Type: research

The Role of the plasma glycosylated hemoglobin A1c/Apolipoprotein A-l ratio in predicting cardiovascular outcomes in acute coronary syndrome
Glucose and lipid metabolism are major prognostic indicators of coronary heart disease. The ratio of plasma glycosylated hemoglobin A1c (HbA1c) to apolipoprotein A-l (ApoA-l) is an indirect measure of insulin resistance. The study aimed to evaluate whether the HbA1c/ApoA-1 ratio can predict the prognosis in patients with the acute coronary syndrome (ACS). (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 19, 2020 Category: Nutrition Authors: Feier Song, Yu Zhou, Kunyi Zhang, Yuan-Feng Liang, Xuyu He, Liwen Li Source Type: research

Barriers to diabetic foot management in Italy: a multicentre survey in diabetic foot centres of the Diabetic Foot Study Group of the Italian Society of Diabetes (SID) and Association of Medical Diabetologists (AMD)
Diabetic foot (DF) disease is a current health and social burden. The Authors aimed to identify the barriers to the DF management across Italy. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 17, 2020 Category: Nutrition Authors: Marco Meloni, Silvia Acquati, Carmelo Licciardello, Ornella Ludovico, Mario Sepe, Cristiana Vermigli, Roberto Da Ros Source Type: research

Predictive value of free triiodothyronine (FT3) to free thyroxine (FT4) ratio in long-term outcomes of euthyroid patients with three-vessel coronary artery disease
This study evaluated the relationship between FT3/FT4 ratio and long-term clinical outcomes in this specific population. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 17, 2020 Category: Nutrition Authors: Deshan Yuan, Ce Zhang, Sida Jia, Yue Liu, Lin Jiang, Lianjun Xu, Yin Zhang, Jingjing Xu, Bo Xu, Rutai Hui, Runlin Gao, Zhan Gao, Lei Song, Jinqing Yuan Source Type: research

Perceptions and expectations of adults with type 1 diabetes for the use of artificial pancreas systems with and without glucagon addition: Results of an online survey
The first hybrid artificial pancreas (AP) systems with insulin only (mono-hormonal) have recently reached the market while next generations systems are under development including those with glucagon addition (bi-hormonal). Understanding the expectations and impressions of future potential users about AP systems is important for optimal use of this clinically effective emerging technology. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 16, 2020 Category: Nutrition Authors: Nadine Taleb, Ariane Quintal, Rohan Rakheja, Virginie Messier, Laurent Legault, Eric Racine, R émi Rabasa-Lhoret Source Type: research

Left ventricular myocardial oxygen demand and subclinical dysfunction in patients with severe obesity referred for bariatric surgery
Increased myocardial oxygen (O2) demand carries higher cardiovascular risk in hypertension. We hypothesized that myocardial O2 demand is increased in severe obesity and linked to early left ventricular (LV) dysfunction. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 16, 2020 Category: Nutrition Authors: Lisa M.D. Grymyr, Saied Nadirpour, Eva Gerdts, Bj ørn G. Nedrebø, Johannes J. Hjertaas, Knut Matre, Dana Cramariuc Source Type: research

Increased visceral fat accumulation modifies the effect of insulin resistance on arterial stiffness and hypertension risk
Both insulin resistance (IR) and visceral adipose tissue (VAT) are related cardiometabolic risk factors, nevertheless its joint effect on endothelial functionality are controversial. To evaluate the joint effect of IR and VAT on endothelial functionality using the pulse-waveform analysis; explore the mediating role of VAT on the effect of IR on arterial pressure, arterial stiffness and incident arterial hypertension. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 14, 2020 Category: Nutrition Authors: Neftali Eduardo Antonio ‐Villa, Omar Yaxmehen Bello‐Chavolla, Arsenio Vargas‐Vázquez, Roopa Mehta, Carlos A. Fermin-Martinez, Alexandro J. Martagón-Rosado, Daphne Abigail Barquera-Guevara, Carlos A. Aguilar-Salinas, the Metabolic Syndrome Study G Source Type: research

Uric acid to high-density lipoprotein cholesterol ratio predicts cardiovascular mortality in patients on peritoneal dialysis
Serum uric acid (UA) and high-density lipoprotein cholesterol (HDL-C) disorders are both considered as risk factors of cardiovascular mortality. The predictive value of UA to HDL-C ratio (UHR) has been validated in diabetes. However, association of UHR with cardiovascular (CV) mortality is undetermined in peritoneal dialysis (PD) patients. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 14, 2020 Category: Nutrition Authors: Ruihua Liu, Yuan Peng, Haishan Wu, Xiangwen Diao, Hongjian Ye, Xuan Huang, Chunyan Yi, Haiping Mao, Fengxian Huang, Xueqing Yu, Xiao Yang Source Type: research

Association between positivity of serum autoantibodies and liver disease severity in patients with biopsy-proven NAFLD
Some previous studies reported serum autoantibody positivity in patients with nonalcoholic fatty liver disease (NAFLD). The clinical significance of these findings remains uncertain. We aimed to investigate the association between the presence of serum autoantibodies and liver disease severity in NAFLD. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 13, 2020 Category: Nutrition Authors: Yu-Jie Zhou, Kenneth I. Zheng, Hong-Lei Ma, Gang Li, Xiao-Yan Pan, Pei-Wu Zhu, Giovanni Targher, Christopher D. Byrne, Xiao-Dong Wang, Yong-Ping Chen, Xiao-Bo Li, Ming-Hua Zheng Source Type: research

Uric acid, impaired fasting glucose and impaired glucose tolerance in youth with overweight and obesity
The relationships between uric acid (UA) and prediabetes is poorly explored in youth. We investigated the association between UA, impaired fasting glucose (IFG), impaired glucose tolerance (IGT), insulin resistance (IR) and low insulin sensitivity (IS) in youth with overweight/obesity (OW/OB). (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 13, 2020 Category: Nutrition Authors: Procolo di Bonito, Giuliana Valerio, Maria Rosaria Licenziati, Giuseppina Campana, Emanuele Miraglia del Giudice, Anna Di Sessa, Anita Morandi, Claudio Maffeis, Claudio Chiesa, Lucia Pacifico, Marco Giorgio Baroni, Melania Manco Source Type: research

Unraveling the link between Metabolic Syndrome and Abdominal aortic calcification
Over the last few decades, the prevalence of metabolic syndrome (MetS) has gradually increased. As we know, many prior studies have connected MetS with diabetes, coronary heart disease, and cardiovascular disease. Abdominal aortic calcification (AAC) is a good marker of morbidity and mortality of vascular disease, as its degree may be associated with the severity of coronary artery calcification and disease. The aim of this article is to investigate the connection between MetS and AAC. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 10, 2020 Category: Nutrition Authors: Shih-Wei Yang, Hui-Fang Yang, Yuan-Yuei Chen, Wei-Liang Chen Source Type: research