Serum Vitamin D Deficiency and Risk of Hospitalization for Heart Failure: Prospective Results from the Moli-sani Study
Evidence indicates that Vitamin D deficiency may be associated with increased risk of cardiovascular disease, however findings on risk of heart failure (HF) are controversial. We investigated the relationship between serum Vitamin D and the incidence of hospitalization for HF in a large prospective cohort of Italian adults. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - December 7, 2017 Category: Nutrition Authors: S. Costanzo, A. De Curtis, A. Di Castelnuovo, M. Persichillo, M. Bonaccio, G. Pounis, C. Cerletti, M.B. Donati, G. de Gaetano, L. Iacoviello, Moli-sani Study Investigators Source Type: research

Inverse association between plasma homocysteine concentrations and type 2 diabetes mellitus among a middle-aged and elderly Chinese population
Plasma homocysteine concentrations have been reported to be associated with type 2 diabetes mellitus (T2DM) with controversial findings. The aim of the present study was to investigate the association between plasma homocysteine concentrations and T2DM. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - December 7, 2017 Category: Nutrition Authors: Caizheng Yu, Jing Wang, Fei Wang, Xu Han, Hua Hu, Jing Yuan, Xiaoping Miao, Ping Yao, Sheng Wei, Youjie Wang, Yuan Liang, Weihong Chen, Xiaomin Zhang, Huan Guo, Handong Yang, Yuhan Tang, Dan Zheng, Tangchun Wu, Meian He Source Type: research

Vitamin D Receptor Activation By Paricalcitol and Insulin Resistance in CKD
The nature of the link (causal vs non-causal) between low 1,25-OH vitamin D and insulin resistance (IR) in patients with chronic kidney disease (CKD) remains elusive. We have now made a post hoc analysis of the effect of vitamin D receptor activation by paricalcitol on IR in the complete dataset of a double-blind, randomized, placebo controlled trial, the Paracalcitol and ENdothelial fuNction in chronic kidneY disease (PENNY). (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - December 7, 2017 Category: Nutrition Authors: B. Spoto, P. Pizzini, S. Cutrupi, G. Tripepi, G. Curatola, F. Mallamaci, C. Zoccali Source Type: research

Differential lipid metabolism outcomes associated with ADRB2 gene polymorphisms in response to two dietary interventions in overweight/obese subjects.
A precise nutrigenetic management of hypercholesterolemia involves the understanding of the interactions between the individual ´s genotype and dietary intake. The aim of this study was to analyze the response to two dietary energy-restricted interventions on cholesterol changes in carriers of two ADRB2 polymorphisms. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - December 4, 2017 Category: Nutrition Authors: O. Ramos-Lopez, J.I. Riezu-Boj, F.I. Milagro, L. Goni, M. Cuervo, J.A. Martinez Source Type: research

Editorial Board
(Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - December 1, 2017 Category: Nutrition Source Type: research

Publish and perish
With this issue I will be concluding my three-year term as Editor-in-Chief of NMCD. It has been an intense, interesting and constructive experience, but also very different from what I had imagined. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - December 1, 2017 Category: Nutrition Authors: Andrea Giaccari Tags: Editorial Source Type: research

Long-term clinical impact of serum albumin in coronary artery disease patients with preserved renal function
Low serum albumin level is reportedly associated with worse clinical outcomes in patients with chronic kidney disease (CKD). However, associations between decreased serum albumin level and outcomes in non-CKD patients with coronary artery disease (CAD) remain unclear. Therefore, we aimed to evaluate the prognostic value of serum albumin concentrations in stable CAD patients with preserved renal function. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 25, 2017 Category: Nutrition Authors: H. Wada, T. Dohi, K. Miyauchi, J. Shitara, H. Endo, S. Doi, H. Konishi, R. Naito, S. Tsuboi, M. Ogita, T. Kasai, A. Hassan, S. Okazaki, K. Isoda, S. Suwa, H. Daida Source Type: research

Molecular analysis of three known and one novel LPL variants in patients with type I hyperlipoproteinemia
Type I hyperlipoproteinemia, also known as familial chylomicronemia syndrome (FCS), is a rare autosomal recessive disorder caused by variants in LPL, APOC2, APOA5, LMF1 or GPIHBP1 genes. The aim of this study was to identify novel variants in the LPL gene causing lipoprotein lipase deficiency and to understand the molecular mechanisms. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 21, 2017 Category: Nutrition Authors: Caddeo Andrea, Mancina Rosellina Margherita, Pirazzi Carlo, Russo Cristina, Sasidharan Kavitha, Sandstedt Joakim, Maurotti Samantha, Montalcini Tiziana, Pujia Arturo, Trond P. Leren, Romeo Stefano, Pingitore Piero Source Type: research

Comment on “Diabetes remission after bariatric surgery is characterized by high glycemic variability and high oxidative stress”
(Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 21, 2017 Category: Nutrition Authors: Aldo Bonaventura, Fabrizio Montecucco Tags: Letter to the Editor Source Type: research

Effects of dark chocolate on endothelial function in patients with non-alcoholic steatohepatitis
Oxidative stress plays a pivotal role in inducing endothelial dysfunction and progression from simple fatty liver steatosis (FLD) to non-alcoholic steatohepatitis (NASH). Polyphenols could reduce oxidative stress and restore endothelial function by inhibiting the nicotinamide-adenine-dinucleotide-phosphate (NADPH) oxidase isoform Nox2. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 13, 2017 Category: Nutrition Authors: Lorenzo Loffredo, Francesco Baratta, Perri Ludovica, Simona Battaglia, Roberto Carnevale, Cristina Nocella, Marta Novo, Gaetano Pannitteri, Fabrizio Ceci, Francesco Angelico, Francesco Violi, Maria Del Ben Source Type: research

Hypertriglyceridemia and omega-3 fatty acids: their often overlooked role in cardiovascular disease prevention
This review aims to describe the pathogenic role of triglycerides in cardiometabolic risk, and the potential role of omega-3 fatty acids in the management of hypertriglyceridemia and cardiovascular disease. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 13, 2017 Category: Nutrition Authors: M. Arca, C. Borghi, R. Pontremoli, G.M. De Ferrari, F. Colivicchi, G. Desideri, P.L. Temporelli Tags: Review Source Type: research

The relationship of health/food literacy and salt awareness to daily sodium and potassium intake among a workplace population in Switzerland
This study explored the associations of health literacy (HL), food literacy (FL), and salt awareness with salt intake, K intake, and Na/K ratio in a workplace intervention trial in Switzerland. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 13, 2017 Category: Nutrition Authors: X. Luta, S. Hayoz, C. Gr éa Krause, K. Sommerhalder, E. Roos, P. Strazzullo, S. Beer-Borst Source Type: research

Freestyle Libre and Dexcom G4 Platinum sensors: accuracy comparisons during two weeks of home use and use during experimentally induced glucose excursions.
This study compared the accuracy of the FreeStyle Libre (Abbott, Alameda, CA) and Dexcom G4 Platinum (DG4P, Dexcom, San Diego, CA) CGM sensors. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 11, 2017 Category: Nutrition Authors: F. Boscari, S. Galasso, A. Facchinetti, M. Marescotti, V. Vallone, A. Amato, A. Avogaro, D. Bruttomesso Source Type: research

Dietary patterns and the risk of coronary heart disease among Jordanians: A case –control study
This study aimed to evaluate several dietary choices and their potential association with CHD. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 8, 2017 Category: Nutrition Authors: R.F. Tayyem, A.E. Al-Shudifat, A. Johannessen, H.A. Bawadi, S.S. AbuMweis, L.M. Agraib, S.S. Allhedan, I. Haj-Husein, M. Azab Source Type: research

Dietary patterns and the risk of coronary heart disease among Jordanians
This study aimed to evaluate several dietary choices and their potential association with CHD. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 8, 2017 Category: Nutrition Authors: Reema F. Tayyem, Abdel-Ellah Al-Shudifat, Asgeir Johannessen, Hiba A. Bawadi, Suhad S. AbuMweis, Lana M. Agraib, Sabika S. Allhedan, Isra'a Haj-Husein, Mohammed Azab Source Type: research

Longitudinal association of metabolic syndrome and dietary patterns: A 13-year prospective population-based cohort study
Diet is a potential factor contributing to the development of Metabolic Syndrome (MetS). This longitudinal study with repeated measurements of dietary intake was thus conducted to examine the longitudinal association between major dietary patterns and risk of MetS. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 6, 2017 Category: Nutrition Authors: R. Hassannejad, I. Kazemi, M. Sadeghi, N. Mohammadifard, H. Roohafza, N. Sarrafzadegan, M. Talaei, M. Mansourian Source Type: research

Neutrophil-to-Lymphocyte Ratio is a strong predictor of atherosclerotic carotid plaques in older adults
This study aims to assess this association which gives additional value to this biomarker, with respect to the main risk factors, in the prediction of carotid atherosclerosis in older adults. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 5, 2017 Category: Nutrition Authors: T. Corriere, S. Di Marca, E. Cataudella, A. Pulvirenti, S. Alaimo, B. Stancanelli, L. Malatino Source Type: research

Neutrophil To Lymphocyte Ratio Is A Strong Predictor Of Atherosclerotic Carotid Plaques In Older Adults
This study aims to assess this association which gives additional value to this biomarker, with respect to the the main risk factors, in the prediction of carotid atherosclerosis in older adults. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 5, 2017 Category: Nutrition Authors: T. Corriere, S. Di Marca, E. Cataudella, A. Pulvirenti, S. Alaimo, B. Stancanelli, L. Malatino Source Type: research

Different protein composition of low-calorie diet differently impacts adipokine profile irrespective of weight loss in overweigh and obese women
High protein (HP) diets have shown benefits in cardiometabolic markers such as insulin or triglycerides but the responsible mechanisms are not known. We aimed to assess the effect of three energy-restricted diets with different protein content (20, 27 and 35%; ∼80% coming from animal source) on plasma adipokine concentration and its association with changes in cardiometabolic markers. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 4, 2017 Category: Nutrition Authors: Roc ío Mateo-Gallego, Itziar Lamiquiz-Moneo, Sofía Perez-Calahorra, Victoria Marco-Benedí, Ana M. Bea, Lucía Baila-Rueda, Martín Laclaustra, José L. Peñalvo, Fernando Civeira, Ana Cenarro Source Type: research

Relationship between spicy flavor, spicy food intake frequency, and general obesity in a rural adult Chinese population: The RuralDiab study
The purpose of this study was to explore the association between spicy flavor, spicy food frequency, and general obesity in Chinese rural adults. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 2, 2017 Category: Nutrition Authors: K. Yang, Y. Li, Z. Mao, X. Liu, H. Zhang, R. Liu, Y. Xue, R. Tu, X. Liu, X. Zhang, W. Li, C. Wang Source Type: research

Relationship between spicy flavor, spicy food intake frequency and general obesity in a rural adult Chinese population: the RuralDiab Study
The purpose of this study was to explore the association between the spicy flavor, spicy food frequency and general obesity in Chinese rural adults. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 2, 2017 Category: Nutrition Authors: Kaili Yang, Yuqian Li, Zhenxing Mao, Xiaotian Liu, Honglei Zhang, Ruihua Liu, Yuan Xue, Runqi Tu, Xinxin Liu, Xiaofeng Zhang, Wenjie Li, Chongjian Wang Source Type: research

Editorial Board
(Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - November 1, 2017 Category: Nutrition Source Type: research

Position Paper on Vegetarian Diets from the Working Group of the Italian Society of Human Nutrition
Interest in eating a vegetarian diet is growing in Italy and elsewhere, as government agencies and health and nutrition organizations are emphasizing that regular consumption of plant foods may provide health benefits and help prevent certain diseases. The studies reviewed in this position paper make it clear that vegetarian diets that include a wide variety of plant products and a reliable source of vitamin B12 provide adequate nutrient intake for people of all ages. Vegetarians should, however, be encouraged to supplement their diets with a reliable source of vitamin B12 (vitamin-fortified foods or supplements). (Source:...
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 31, 2017 Category: Nutrition Authors: Claudia Agnoli, Luciana Baroni, Iacopo Bertini, Salvatore Ciappellano, Alessandra Fabbri, Mattia Papa, Nicoletta Pellegrini, Rosella Sbarbati, Maria Laura Scarino, Vincenzino Siani, Sabina Sieri Source Type: research

Correlates of ideal cardiovascular health in European adolescents: The HELENA study
The ideal cardiovascular health (iCVH) construct consists of 4 health behaviors (smoking status, body mass index, physical activity and diet) and 3 health factors (total cholesterol, blood pressure and fasting glucose). A greater number of iCVH components in adolescence is related to better cardiovascular health, but little is known about the correlates of iCVH in adolescents. Thus, the aim of the study was to examine correlates of iCVH in European adolescents. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 27, 2017 Category: Nutrition Authors: Pontus Henriksson, Hanna Henriksson, Idoia Labayen, Inge Huybrechts, Luis Gracia-Marco, Francisco B. Ortega, Vanesa Espa ña-Romero, Yannis Manios, Marcela González-Gross, Ascensión Marcos, Luis A. Moreno, Ángel Gutiérrez, Jonatan R. Ruiz, HELENA stud Source Type: research

The association between serum uric acid and asymptomatic intracranial arterial stenosis in middle-aged Koreans
Intracranial arterial stenosis (ICAS) is one of the most common causes of stroke, especially in Asians. Hyperuricemia has been associated with an increased risk of comorbidities such as metabolic syndrome or cardiovascular diseases. However, there are few studies focusing on the association between serum uric acid (SUA) levels and asymptomatic ICAS. The aim of this study was to explore the association between SUA and the prevalence of ICAS in middle-aged Korean health screening examinees. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 27, 2017 Category: Nutrition Authors: J.K. Ahn, J. Hwang, J.H. Hwang, W.T. Yoon, P.W. Chung, S. Ryu Source Type: research

Gut microbiome composition in lean patients with NASH is associated with liver damage independent of caloric intake: A  prospective pilot study
The aim of the study was to compare the gut microbiomes from obese and lean patients with or without NASH to outline phenotypic differences. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 26, 2017 Category: Nutrition Authors: S.M.B. Duarte, J.T. Stefano, L. Miele, F.R. Ponziani, M. Souza-Basqueira, L.S.R.R. Okada, F.G. de Barros Costa, K. Toda, D.F.C. Mazo, E.C. Sabino, F.J. Carrilho, A. Gasbarrini, C.P. Oliveira Source Type: research

Familial diabetes of adulthood: A bin of ignorance that needs to be addressed
The aim of this article was to share with a wide readership some data and related reasoning about a multigenerational form of diabetes mellitus of adulthood. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 26, 2017 Category: Nutrition Authors: S. Prudente, O. Ludovico, V. Trischitta Tags: Commentary Source Type: research

Aging process, adherence to Mediterranean diet and nutritional status in a large cohort of nonagenarians: effects on endothelial progenitor cells
Adherence to the Mediterranean Diet (MD) has been associated with a longer and better life. The aim of this study was to examine the effects of adherence to the MD, and of nutritional habits on endothelial progenitor (EPCs) and circulating progenitor (CPCs) cells in a cohort of nonagenarians enrolled within the Mugello Study, an epidemiological study aimed at investigating both clinically relevant geriatric items and various health issues, including those related to nutritional status. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 26, 2017 Category: Nutrition Authors: Francesca Cesari, Francesco Sofi, Raffaello Molino Lova, Federica Vannetti, Guido Pasquini, Francesca Cecchi, Rossella Marcucci, Anna Maria Gori, Claudio Macchi, The MUGELLO STUDY WORKING GROUP Source Type: research

Gut microbiome composition in lean patients with NASH is associated with liver damage independent from caloric intake: a prospective pilot study
/Aim: The aim of the study was to compare the gut microbiomes from obese and lean patients with or without NASH to outline phenotypic differences. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 26, 2017 Category: Nutrition Authors: Sebasti ão Mauro Bezerra Duarte, José Tadeu Stefano, Luca Miele, Francesca Romana Ponziani, Marcela de Souza, Lívia Rodrigues, Fernando Gomes de Barros Costa, Karla Toda, Daniel Ferraz Campos Mazo, Ester Cerdeira Sabino, Flair José Carrilho, Antonio G Source Type: research

The Clinical Potential of Adipogenesis and Obesity-related MicroRNAs
Obesity is a growing health problem commonly associated with numerous metabolic disorders including type 2 diabetes, hypertension, cardiovascular disease, and some forms of cancer. The burden of obesity and associated cardiometabolic diseases are believed to arise through complex interplay between genetics and epigenetics predisposition, nutrition, environment, and lifestyle. However, the molecular basis and the repertoire of obesity-affecting factors are still unknown. Emerging evidence is connecting microRNAs (miRNAs) dysregulation with adipogenesis and obesity. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 26, 2017 Category: Nutrition Authors: Mohamed Zaiou, Hamid El Amri, Ahmed Bakillah Tags: Review Source Type: research

Familial diabetes of the adulthood: a bin of ignorance that need to be addressed
The aim of this article was to share with a wide readership some data and related reasoning about a multigenerational form of diabetes mellitus of the adulthood. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 26, 2017 Category: Nutrition Authors: Sabrina Prudente, Ornella Ludovico, Vincenzo Trischitta Tags: Viewpoint Source Type: research

Low vitamin D status in relation to cardiovascular disease and mortality in Swedish women – Effect of extended follow-up
The impact of vitamin D concentrations on subsequent cardiovascular disease (CVD) and overall mortality has been generally examined for periods under two decades. The magnitude of the association may depend on follow-up length. We aimed to investigate the relationship between baseline vitamin D and risk of total CVD, stroke and all-cause mortality over three decades of follow-up. Secondly, we aimed to assess how follow-up affects the associations. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 25, 2017 Category: Nutrition Authors: M. Leu Agelii, S. Lehtinen-Jacks, H. Zetterberg, V. Sundh, C. Bj örkelund, L. Lissner Source Type: research

Low vitamin D status in relation to cardiovascular disease and mortality in Swedish women - effect of extended follow-up
The impact of vitamin D concentrations on subsequent cardiovascular disease (CVD) and overall mortality has been generally examined for periods under two decades. The magnitude of the association may depend on follow-up length. We aimed to investigate the relationship between baseline vitamin D and risk of total CVD, stroke and all-cause mortality over three decades of follow-up. Secondly, we aimed to assess how follow-up affects the associations. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 25, 2017 Category: Nutrition Authors: Monica Leu Agelii, Susanna Lehtinen-Jacks, Henrik Zetterberg, Valter Sundh, Cecilia Bj örkelund, Lauren Lissner Source Type: research

Hyperthyroxinemia is positively associated with prevalent and incident type 2 diabetes mellitus in two population-based samples from Northeast Germany and Denmark
A potential causal relationship between thyroid function and type 2 diabetes mellitus is currently under debate, but the current state of research is limited. Our aim was to investigate the association of thyroid hormone levels with prevalent and incident type 2 diabetes mellitus (T2DM) in two representative studies. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 25, 2017 Category: Nutrition Authors: T. Ittermann, S. Schipf, M. D örr, B.H. Thuesen, T. Jørgensen, H. Völzke, M.R.P. Markus Source Type: research

Adverse events with sodium-glucose co-transporter-2 inhibitors: A  global analysis of international spontaneous reporting systems
We assessed post-marketing safety of sodium-glucose co-transporter-2 inhibitors (SGLT2-Is) by analyzing adverse events (AEs) reported in international pharmacovigilance databases. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 17, 2017 Category: Nutrition Authors: E. Raschi, M. Parisotto, E. Forcesi, M. La Placa, G. Marchesini, F. De Ponti, E. Poluzzi Source Type: research

Adverse events with sodium-glucose co-transporter-2 inhibitors: a global analysis of international spontaneous reporting systems
We assessed post-marketing safety of sodium-glucose co-transporter-2 inhibitors (SGLT2-Is) by analyzing adverse events (AEs) reported in international pharmacovigilance databases. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 17, 2017 Category: Nutrition Authors: E. Raschi, M. Parisotto, E. Forcesi, M. La Placa, G. Marchesini, F. De Ponti, E. Poluzzi Source Type: research

Association of serum fibroblast growth factor 19 levels with visceral fat accumulation is independent of glucose tolerance status
This study aimed to investigate the association of serum FGF19 levels with obesity and visceral fat accumulation in a Chinese population with differing glucose tolerance status. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 17, 2017 Category: Nutrition Authors: Xiang Hu, MD, Qin Xiong, MD, Yiting Xu, Xueli Zhang, Xiaoping Pan, Xiaojing Ma, PhD. MD, Yuqian Bao, MD, Weiping Jia, Hu X, Xiong Q, Xu Y, Zhang X, Pan X, Ma X, Bao Y, Jia W Source Type: research

A systematic review of the effect of dietary saturated and polyunsaturated fat on heart disease
Over the last 7 years there has been intense debate about the advice to reduce saturated fat and increase polyunsaturated fat to reduce CVD risk. The aim of this review was to examine systematic reviews and meta-analyses since 2010 on this topic plus additional cohort studies and interventions not included in these reviews. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 17, 2017 Category: Nutrition Authors: Peter M. Clifton, Jennifer B. Keogh Source Type: research

Acute Renal Failure with Sodium-Glucose-Cotransporter-2 Inhibitors: Analysis of the FDA Adverse Event Report System Database
This study aimed to evaluate the association between SGLT2-inhibitors and ARF in the FDA adverse event report system (FAERS) database. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 17, 2017 Category: Nutrition Authors: Amichai Perlman, Samuel N. Heyman, Ilan Matok, Joshua Stokar, Mordechai Muszkat, Auryan Szalat Source Type: research

Interrelationship of the rs7903146 TCF7L2 gene variant with measures of glucose metabolism and adiposity: the NEO Study
We investigated the interrelationship of rs7903146-T in TCF7L2 with measures of glucose metabolism and measures of adiposity. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 17, 2017 Category: Nutrition Authors: R. Noordam, C.P.A. Zwetsloot, R. de Mutsert, D.O. Mook-Kanamori, H.J. Lamb, A. de Roos, E.J.P. de Koning, F.R. Rosendaal, K. Willems van Dijk, D. van Heemst Source Type: research

Sleep-disordered breathing and epicardial adipose tissue in patients with heart failure
Sleep-disordered breathing (SDB) is common in patients with heart failure (HF), contributes to the progression of cardiac disease, and is associated with adverse prognosis. Previous evidence indicates that epicardial adipose tissue (EAT) is independently associated with sleep apnea in obese individuals. We explored the relationship between SDB and EAT in HF patients. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 13, 2017 Category: Nutrition Authors: V. Parisi, S. Paolillo, G. Rengo, R. Formisano, L. Petraglia, F. Grieco, C. D'Amore, S. Dellegrottaglie, C. Marciano, N. Ferrara, D. Leosco, P.P. Filardi Source Type: research

Prediabetes is associated with lower brain gray matter volume in the general population. The Study of Health in Pomerania (SHIP)
We investigated the associations of fasting (FG) and 2-h  postload (2HG) plasma glucose from oral glucose tolerance test (OGTT) with gray (GMV) and white (WMV) matter volume. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 13, 2017 Category: Nutrition Authors: M.R.P. Markus, T. Ittermann, K. Wittfeld, S. Schipf, U. Siewert-Markus, M. Bahls, R. B ülow, N. Werner, D. Janowitz, S.E. Baumeister, S.B. Felix, M. Dörr, W. Rathmann, H. Völzke, H.J. Grabe Tags: Meta-analysis Source Type: research

Inflammation in metabolically healthy and metabolically abnormal adolescents: the HELENA study
Inflammation may influence the cardio-metabolic profile which relates with the risk of chronic diseases. To assess the inflammatory status by metabolic health/body mass index (BMI) category and to assess how inflammatory markers can predict the cardio-metabolic profile in European adolescents, considering BMI. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 13, 2017 Category: Nutrition Authors: Esther Mar ía Gonzalez-Gil, Cristina Cadenas-Sanchez, Javier Santabárbara, Gloria Bueno-Lozano, Iris Iglesia, Marcela González-Gross, Denes Molnar, Frederic Gottrand, Stefaan De Henauw, Antonios Kafatos, Kurt Widhalm, Yannis Manios, Alfonso Siani, Fran Source Type: research

Impaired beta cell sensitivity to incretins in type 2 diabetes is insufficiently compensated by higher incretin response
The incretin effect is impaired in type 2 diabetes (T2D), but the underlying mechanisms are only partially understood. We investigated the relationships between the time course of the incretin effect and that of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) during oral glucose tolerance tests (OGTTs), thereby estimating incretin sensitivity of the beta cell, and its associated factors. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 13, 2017 Category: Nutrition Authors: A. Tura, J.I. Bagger, E. Ferrannini, J.J. Holst, F.K. Knop, T. Vilsb øll, A. Mari Source Type: research

Sleep disordered breathing and epicardial adipose tissue in patients with heart failure
Sleep-disordered breathing (SDB) is common in patients with heart failure (HF), contributes to the progression of cardiac disease and is associated to adverse prognosis. Previous evidences indicate that epicardial adipose tissue (EAT) is independently associated with sleep apnea in obese individuals. We explored the relationship between SDB and EAT in HF patients. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 13, 2017 Category: Nutrition Authors: Valentina Parisi, Stefania Paolillo, Giuseppe Rengo, Roberto Formisano, Laura Petraglia, Fabrizio Grieco, Carmen D ’Amore, Santo Dellegrottaglie, Caterina Marciano, Nicola Ferrara, Dario Leosco, Pasquale Perrone Filardi Source Type: research

Dietary total, animal, vegetable calcium and type 2 diabetes incidence among Korean adults: The Korean Multi-Rural Communities Cohort (MRCohort)
This study aimed to evaluate the prospective association between dietary calcium and T2D incidece among adults 40 years of age or over, from the Multi-rural Communities Cohort (MRCohort), South Korea. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 13, 2017 Category: Nutrition Authors: Jin Myoung Oh, Hye Won Woo, Mi Kyung Kim, Young-Hoon Lee, Dong Hoon Shin, Min-Ho Shin, Bo Youl Choi Source Type: research

Prediabetes is Associated with Lower Brain Gray Matter Volume in the General Population The Study of Health in Pomerania (SHIP)
We investigated the associations of fasting (FG) and 2-hour postload (2HG) plasma glucose from oral glucose tolerance test (OGTT) with gray (GMV) and white (WMV) matter volume. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 13, 2017 Category: Nutrition Authors: M.R.P. Markus, T. Ittermann, K. Wittfeld, S. Schipf, U. Siewert-Markus, M. Bahls, R. B ülow, N. Werner, D. Janowitz, S.E. Baumeister, S.B. Felix, M. Dörr, W. Rathmann, H. Völzke, H.J. Grabe Source Type: research

The association between muscle mass deficits and arterial stiffness in middle-aged men
Early diagnosis of arteriosclerosis is fundamental for the prevention of cardiovascular morbidity and mortality. The current study was performed to identify major predictors of arteriosclerosis and to assess the association between arterial stiffness as measured by cardio-ankle vascular index (CAVI) and muscle mass deficit (MMD) estimated by bioelectrical impedance analysis (BIA) in middle-aged men. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 11, 2017 Category: Nutrition Authors: I.J. Im, H.J. Choi, S.M. Jeong, H.J. Kim, J.S. Son, H.J. Oh Source Type: research

The Relationship between High-density Lipoprotein Cholesterol Levels and Arterial Stiffness in a Taiwanese Population
There are few studies on the association between HDL-C levels and arterial stiffness (AS). The HDL-C level varies in males and females, and it is not clear whether the relationship between the HDL-C level and AS is influenced by gender. The purpose of this study was to investigate the gender differences in the association between HDL-C levels and AS in adults. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 11, 2017 Category: Nutrition Authors: Wei-Chen Shen, Feng-Hwa Lu, Yi-Ching Yang, Jin-Shang Wu, Yin-Fan Chang, Yao-Hsien Huang, Chih-Jen Chang Source Type: research

Sex differences in associations between blood lipids and cerebral small vessel disease
Dyslipidemia predicts higher risk of coronary events and stroke and might be associated with cerebral small vessel disease (SVD). Previous studies linking blood lipids and SVD have yielded inconsistent results, which may be attributable to sex differences in lipids metabolism. The aim of this study was to investigate the relationships between blood lipids and SVD in neurologically healthy men and women. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 10, 2017 Category: Nutrition Authors: Ze-Gang Yin, Qing-Song Wang, Ke Yu, Wei-Wen Wang, Hang Lin, Zheng-Hui Yang Source Type: research