Pharmacovigilance of sodium-glucose co-transporter-2 inhibitors: What a clinician should know on disproportionality analysis of spontaneous reporting systems
Sodium-glucose co-transporter-2 inhibitors (SGLT2-Is) have consistently demonstrated a clinically significant reduction of cardiovascular mortality. However, their safety in clinical practice is still incompletely characterized, and post-marketing monitoring is required considering the expected increase in clinical use. Different analyses of international spontaneous reporting systems, known as disproportionality analyses (DAs), have highlighted the occurrence of ketoacidosis, amputations, acute renal failure and skin toxicity. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - March 1, 2018 Category: Nutrition Authors: Emanuel Raschi, Elisabetta Poluzzi, Francesco Salvo, Antoine Pariente, Fabrizio De Ponti, Giulio Marchesini, Ugo Moretti Tags: Viewpoint Source Type: research

Fasting and Post-Glucose Load Measures of Insulin Resistance and Risk of Incident Atrial Fibrillation: The Cardiovascular Health Study
Existing literature in individuals without diabetes has not demonstrated a relationship between IR and incident AF; however, data are limited and only fasting glucose measures of IR were assessed. We evaluated the relationship of both fasting and post-glucose load IR measures with the development of atrial fibrillation in nondiabetic older adults. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - March 1, 2018 Category: Nutrition Authors: Parveen K. Garg, Mary L. Biggs, Robert Kaplan, Jorge R. Kizer, Susan R. Heckbert, Kenneth J. Mukamal Source Type: research

B-Type Natriuretic Peptide May Predict Prognosis In Older Adults Admitted With A Diagnosis Other Than Heart Failure
The diagnosis of heart failure (HF) in elderly patients is often difficult, due to overlap of typical signs and symptoms with those of comorbidities. B-type Natriuretic Peptide (BNP) predicts diagnosis and prognosis of HF, but little is known on its predictive role of short-term prognosis when admission diagnosis is other than HF. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - March 1, 2018 Category: Nutrition Authors: S. Di Marca, A. Rando, E. Cataudella, A. Pulvirenti, S. Alaimo, V. Terranova, T. Corriere, M. Pisano, R. Di Quattro, M.L. Ronsisvalle, C.M. Giraffa, M. Giordano, B. Stancanelli, L. Malatino Source Type: research

N-terminal pro B-Type natriuretic peptide is inversely correlated with low density lipoprotein cholesterol in the very elderly
Laboratory studies on human adipose tissue and differentiated adipocytes indicate that natriuretic peptides (NPs) affect lipid metabolism and plasma cholesterol. Few previous clinical studies in non-elderly populations found associations between NPs in the physiological range and cholesterol. Aim: evaluate the association between NT-proBNP and lipid profile in very elderly hospitalized patients characterized by a wide range of NT-proBNP levels. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 27, 2018 Category: Nutrition Authors: F. Spannella, F. Giulietti, G. Cocci, L. Landi, E. Borioni, F.E. Lombardi, G. Rosettani, B. Bernardi, V. Bordoni, P. Giordano, M. Bordicchia, R. Sarzani Source Type: research

N-Terminal Pro B-Type Natriuretic Peptide Is Inversely Correlated With Low Density Lipoprotein Cholesterol In The Very Elderly
Laboratory studies on human adipose tissue and differentiated adipocytes indicate that natriuretic peptides (NPs) affect lipid metabolism and plasma cholesterol. Few previous clinical studies in non-elderly populations found associations between NPs in the physiological range and cholesterol. Aim: evaluate the association between NT-proBNP and lipid profile in very elderly hospitalized patients characterized by a wide range of NT-proBNP levels. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 27, 2018 Category: Nutrition Authors: F. Spannella, F. Giulietti, G. Cocci, L. Landi, E. Borioni, Fe Lombardi, G. Rosettani, B. Bernardi, V. Bordoni, P. Giordano, M. Bordicchia, R. Sarzani Source Type: research

Long-acting insulin analogs and cancer
Hyperinsulinemia is a recognized risk factor for cancer and plays a major role for the  increased cancer incidence in diabetic patients. Whether insulin analogs, and particularly long-acting analogs, worsen the pro-cancer effect of excess insulin is still controversial. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 24, 2018 Category: Nutrition Authors: L. Sciacca, V. Vella, L. Frittitta, A. Tumminia, L. Manzella, S. Squatrito, A. Belfiore, R. Vigneri Tags: Review Source Type: research

Diabetes mellitus and the risk of sudden cardiac death: a systematic review and meta-analysis of prospective studies
Although diabetes mellitus is an established risk factor for myocardial infarction and stroke, data on the association with sudden cardiac are less extensive and the findings have not been entirely consistent. We therefore conducted a systematic review and meta-analysis of diabetes mellitus and sudden cardiac death. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 24, 2018 Category: Nutrition Authors: Dagfinn Aune, Sabrina Schlesinger, Teresa Norat, Elio Riboli Tags: Systematic Reviews and Meta-analyses Source Type: research

Cardiac effects of fish oil in a rat model of streptozotocin-induced diabetes
This study aims to evaluate effects of FO in a rat model of streptozotocin (STZ) induced diabetes. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 24, 2018 Category: Nutrition Authors: F. Mayyas, R. Jaradat, K.H. Alzoubi Source Type: research

Long-acting Insulin Analogs and Cancer
Hyperinsulinemia is a recognized risk factor for cancer and plays a major role for the increased cancer incidence in diabetic patients. Whether insulin analogs, and particularly long-acting analogs, worsen the pro-cancer effect of excess insulin is still controversial.In this paper we summarize the biological bases for the potential detrimental effect of long-acting analogs on cancer cells and review the in vitro and in vivo evidences on this issue.Because of their different molecular structure relative to native insulin, insulin analogs may activate the insulin receptor (IR) and the post receptor pathways differently. (So...
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 24, 2018 Category: Nutrition Authors: L. Sciacca, V. Vella, L. Frittitta, A. Tumminia, L. Manzella, S. Squatrito, A. Belfiore, R. Vigneri Tags: Review Source Type: research

Diabetes mellitus and the risk of sudden cardiac death: a systematic review and meta-analysis of prospective studies
Although diabetes mellitus is an established risk factor for myocardial infarction and stroke, data on the association with sudden cardiac are less extensive and the findings have not been entirely consistent. We therefore conducted a systematic review and meta-analysis of diabetes mellitus and sudden cardiac death. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 24, 2018 Category: Nutrition Authors: Dagfinn Aune, Sabrina Schlesinger, Teresa Norat, Elio Riboli Tags: Systematic Reviews and Meta-analyses Source Type: research

Cardiac effects of fish oil in a rat model of streptozotocin-induced diabetes
This study aims to evaluate effects of FO in a rat model of streptozotocin (STZ) induced diabetes. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 24, 2018 Category: Nutrition Authors: F. Mayyas, R. Jaradat, K.H. Alzoubi Source Type: research

Reply to “Dietary patterns and the risk of coronary heart disease among Jordanians: A case-control study. Statistical and methodological issues”
We thank Abdollahpour and Salimi [1] for their comments and questions on our paper [2]. We do agree with Dr Salimi that not adjusting for age and gender while estimating odd ratios (ORs) may lead to biased results. In fact, we first estimated the ORs with the adjustment for age and gender but during the reviewing process, one of the reviewer suggested that as already age and gender have been matched, there is no need adjust for age and gender. Therefore, we re-estimated the ORs without using the age and gender as confounding factors. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 22, 2018 Category: Nutrition Authors: R. Tayyem Tags: Letter to the Editor Source Type: research

Dietary patterns and the risk of coronary heart disease among Jordanians: A case-control study. Statistical and methodological issue
We read with great interest the case-control study by Tayyem et  al. [1], in which 400 patients with clinical suspicion of coronary artery disease were investigated for investigating the possible association between dietary patterns and CHD. The authors concluded that the healthy dietary pattern and the high-fiber pattern were associated with a decrease in the odds of CHD among Jordanians. Although the results are quite interesting, there are some issues threatening the validity of estimated ORs. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 22, 2018 Category: Nutrition Authors: I. Abdollahpour, Y. Salimi Tags: Letter to the Editor Source Type: research

Reply to “Dietary patterns and the risk of coronary heart disease among Jordanians: A case-control study. Statistical and methodological issues”
We thank Abdollahpour and Salimi [1] for their comments and questions on our paper [2]. We do agree with Dr Salimi that not adjusting for age and gender while estimating odd ratios (ORs) may lead to biased results. In fact, we first estimated the ORs with the adjustment for age and gender but during the reviewing process, one of the reviewer suggested that as already age and gender have been matched, there is no need adjust for age and gender. Therefore, we re-estimated the ORs without using the age and gender as confounding factors. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 22, 2018 Category: Nutrition Authors: R. Tayyem Tags: Letter to the Editor Source Type: research

Reply to “Comments on ‘Dietary patterns and the risk of coronary heart disease among Jordanians: A case-control study. Statistical and methodological issues’”
We thank Abdollahpour and Salimi [1] for their comments and questions on our paper [2]. We do agree with Dr Salimi that not adjusting for age and gender while estimating odd ratios (ORs) may lead to biased results. In fact, we first estimated the ORs with the adjustment for age and gender but during the reviewing process, one of the reviewer suggested that as already age and gender have been matched, there is no need adjust for age and gender. Therefore, we re-estimated the ORs without using the age and gender as confounding factors. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 22, 2018 Category: Nutrition Authors: R. Tayyem Tags: Letter to the Editor Source Type: research

"Response to 'Dietary patterns and the risk of coronary heart disease among Jordanians: A case-control study. Statistical and methodological issues" by Abdollahpour and Salimi."
(Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 22, 2018 Category: Nutrition Authors: Reema Tayyem Tags: Letters to the Editor Source Type: research

Dietary patterns and the risk of coronary heart disease among Jordanians: A case-control study. Statistical and methodological issue
(Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 22, 2018 Category: Nutrition Authors: Ibrahim Abdollahpour, Yahya Salimi Tags: Letters to the Editor Source Type: research

Metabolic syndrome associates with left atrial dysfunction
Obesity and metabolic syndrome (MetS) are risk factors of atrial fibrillation (AF), but limited data exist on their effect on left atrial (LA) function. The aim of the study was to evaluate the effects of cardiac, hepatic and intra-abdominal ectopic fat depots and cardiometabolic risk factors on LA function in non-diabetic male subjects. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 21, 2018 Category: Nutrition Authors: K. Nyman, M. Gran ér, M.O. Pentikäinen, J. Lundbom, A. Hakkarainen, R. Sirén, M.S. Nieminen, M.-R. Taskinen, N. Lundbom, K. Lauerma Source Type: research

Food insecurity and Mediterranean diet adherence among Greek university students
To assess Mediterranean diet (MD) adherence and food insecurity (FI) among university students in Greece. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 20, 2018 Category: Nutrition Authors: X. Theodoridis, M.G. Grammatikopoulou, K. Gkiouras, S.E. Papadopoulou, T. Agorastou, I. Gkika, M.I. Maraki, T. Dardavessis, M. Chourdakis Source Type: research

Food Insecurity and Mediterranean diet adherence among Greek University students
To assess Mediterranean diet (MD) adherence and food insecurity (FI) among university students in Greece. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 20, 2018 Category: Nutrition Authors: X. Theodoridis, M.G. Grammatikopoulou, K. Gkiouras, S.E. Papadopoulou, T. Agorastou, I. Gkika, M.I. Maraki, T. Dardavessis, M. Chourdakis Source Type: research

Cardiovascular risk biomarkers and metabolically unhealthy status in prepubertal children: Comparison of definitions
The early onset of cardio-metabolic abnormalities, known as metabolically unhealthy (MU) status, is highly associated with obesity and cardiovascular disease (CVD), as well as with increased morbidity and mortality later in life. Given the lack of a consensus MU classification for prepubertal children, we aimed to compare available MU definitions in terms of their association with CVD risk biomarkers. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 17, 2018 Category: Nutrition Authors: A.I. Rup érez, J. Olza, M. Gil-Campos, R. Leis, G. Bueno, C.M. Aguilera, A. Gil, L.A. Moreno Source Type: research

Cardiovascular Risk Biomarkers and Metabolically Unhealthy Status in Prepubertal Children: Comparison of Definitions
The early onset of cardio-metabolic abnormalities, known as metabolically unhealthy (MU) status, is highly associated with obesity and cardiovascular disease (CVD), as well as with increased morbidity and mortality later in life. Given the lack of a consensus MU classification for prepubertal children, we aimed to compare available MU definitions in terms of their association with CVD risk biomarkers. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 17, 2018 Category: Nutrition Authors: A.I. Rup érez, J. Olza, M. Gil-Campos, R. Leis, G. Bueno, C.M. Aguilera, A. Gil, L.A. Moreno Source Type: research

Energy utilization associated with regular activity breaks and continuous physical activity: A randomized crossover trial
To quantify and compare energy utilization associated with prolonged sitting alone, or interrupted with regular activity breaks and/or an additional bout of continuous physical activity. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 12, 2018 Category: Nutrition Authors: S.P. Fenemor, A.R. Homer, T.L. Perry, C.M. Skeaff, M.C. Peddie, N.J. Rehrer Source Type: research

Effect of nutrient deprivation on the expression and the epigenetic signature of sirtuin genes
Over the last decades advances in understanding the molecular bases of the close relationship between nutrition, metabolism, and diseases have been impressive. However, there are always novel frontiers coming up and epigenetics is one of these. Sirtuins, are pivotal factors in the control of metabolic pathways according to nutrient availability. In the present study we evaluated the effect of nutrient deprivation on expression, DNA methylation and chromatin status of the sirtuin genes. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 12, 2018 Category: Nutrition Authors: A. Zullo, E. Simone, M. Grimaldi, M. Gagliardi, L. Zullo, M.R. Matarazzo, F.P. Mancini Source Type: research

Impact of weight loss on epicardial fat and carotid intima media thickness after laparoscopic sleeve gastrectomy: A prospective study
Cardiovascular disease (CVD) is one of the leading causes of mortality in obese patients. We aimed to investigate the influence of significant weight loss following laparoscopic sleeve gastrectomy (LSG) on carotid intima media thickness (CIMT) and epicardial fat thickness (EFT) which are the independent predictors of subclinical atherosclerosis. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 9, 2018 Category: Nutrition Authors: C. Altin, V. Erol, E. Aydin, M. Yilmaz, M.A. Tekindal, L.E. Sade, H. Gulay, H. Muderrisoglu Source Type: research

Impact of Weight Loss on Epicardial Fat and Carotid Intima Media Thickness after Laparoscopic Sleeve Gastrectomy: A prospective study
Cardiovascular disease (CVD) is one of the leading causes of mortality in obese patients. We aimed to investigate the influence of significant weight loss following laparoscopic sleeve gastrectomy (LSG) on carotid intima media thickness (CIMT) and epicardial fat thickness (EFT) which are the independent predictors of subclinical atherosclerosis. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 9, 2018 Category: Nutrition Authors: C. Altin, V. Erol, E. Aydin, M. Yilmaz, M.A. Tekindal, L.E. Sade, H. Gulay, H. Muderrisoglu Source Type: research

Editorial Board
(Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 8, 2018 Category: Nutrition Source Type: research

Dietary inflammatory index or Mediterranean diet score as risk factors for total and cardiovascular mortality
Dietary patterns are associated with risk of cardiovascular disease (CVD). We aimed to examine associations of the Dietary Inflammatory Index (DII) and the Mediterranean Diet Score (MDS) with total, cardiovascular disease (CVD) and coronary heart disease (CHD) mortality in the Melbourne Collaborative Cohort Study; and compare the strengths of the associations. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 6, 2018 Category: Nutrition Authors: A.M. Hodge, J.K. Bassett, P.-A. Dugu é, N. Shivappa, J.R. Hébert, R.L. Milne, D.R. English, G.G. Giles Source Type: research

Coffee consumption and risk of aortic valve stenosis: A prospective study
Coffee contains many biologically active compounds with potential adverse or beneficial effects on the cardiovascular system. Whether coffee consumption is associated with the risk of aortic valve stenosis (AVS) is unknown. The purpose of this study was therefore to examine the association between coffee consumption and AVS incidence. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 6, 2018 Category: Nutrition Authors: S.C. Larsson, A. Wolk, N. H åkansson, M. Bäck Source Type: research

Dietary inflammatory index or Mediterranean diet score as risk factors for total and cardiovascular mortality
Dietary patterns are associated with risk of cardiovascular disease (CVD). We aimed to examine associations of the Dietary Inflammatory Index (DII) and the Mediterranean Diet Score (MDS) with total, cardiovascular disease (CVD) and coronary heart disease (CHD) mortality in the Melbourne Collaborative Cohort Study; and compare the strengths of the associations. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 6, 2018 Category: Nutrition Authors: A.M. Hodge, J.K. Bassett, P.-A. Dugu é, N. Shivappa, J.R. Hébert, R.L. Milne, D.R. English, G.G. Giles Source Type: research

Coffee consumption and risk of aortic valve stenosis: a prospective study
Coffee contains many biologically active compounds with potential adverse or beneficial effects on the cardiovascular system. Whether coffee consumption is associated with the risk of aortic valve stenosis (AVS) is unknown. The purpose of this study was to therefore to examine the association between coffee consumption and AVS incidence. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 6, 2018 Category: Nutrition Authors: Susanna C. Larsson, Alicja Wolk, Niclas H åkansson, Magnus Bäck Source Type: research

Dairy shows different associations with abdominal and BMI-defined overweight: Cross-sectional analyses exploring a variety of dairy products
Previous studies have suggested weight –regulatory properties for several dairy nutrients, but population-based studies on dairy and body weight are inconclusive. We explored cross–sectional associations between dairy consumption and indicators of overweight. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 4, 2018 Category: Nutrition Authors: E.M. Brouwer-Brolsma, D. Sluik, C.M. Singh-Povel, E.J.M. Feskens Source Type: research

Phenylketonuric Diet Negatively Impacts On Butyrate Production
Phenylalanine (Phe) restricted diet, combined with Phe-free L-amino acid supplementation, is the mainstay of treatment for phenylketonuria (PKU). Being the diet a key factor modulating gut microbiota composition, the aim of the present paper was to compare dietary intakes, gut microbiota biodiversity and short chain fatty acids (SCFAs) production in children with PKU, on low-Phe diet, and in children with mild hyperphenylalaninemia (MHP), on unrestricted diet. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 4, 2018 Category: Nutrition Authors: E. Verduci, F. Moretti, G. Bassanini, G. Banderali, V. Rovelli, M.C. Casiraghi, G. Morace, F. Borgo, E. Borghi Source Type: research

Dairy shows different associations with abdominal and BMI-defined overweight: cross-sectional analyses exploring a variety of dairy products
Previous studies suggest weight-regulatory properties for several dairy nutrients, but population-based studies on dairy and body weight are inconclusive. We explored cross-sectional associations between dairy consumption and indicators of overweight. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 4, 2018 Category: Nutrition Authors: E.M. Brouwer-Brolsma, D. Sluik, C.M. Singh-Povel, E.J.M. Feskens Source Type: research

Association between habitual coffee consumption and metabolic syndrome in type 1 diabetes
In the general population, habitual coffee consumption is inversely associated with the metabolic syndrome, a syndrome that is rather common also in patients with type 1 diabetes. However, whether coffee intake is beneficially related to the metabolic syndrome also in type 1 diabetes, is not known. We, therefore, studied the potential association between coffee consumption and the metabolic syndrome in a large population of individuals with type 1 diabetes. Furthermore, we investigated whether coffee consumption is associated with insulin resistance (estimated glucose disposal rate, eGDR), kidney function (estimated glomer...
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 3, 2018 Category: Nutrition Authors: B. Stutz, A.J. Ahola, V. Harjutsalo, C. Forsblom, P.-H. Groop, the FinnDiane Study Group Source Type: research

Serum calcium levels independently predict in-hospital mortality in patients with acute myocardial infarction
Serum calcium levels (sCa) were reported to be associated with cardiovascular risk factors, incidence of coronary artery disease and acute myocardial infarction (AMI). The current study evaluated the association between sCa and in-hospital mortality among AMI patients. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 3, 2018 Category: Nutrition Authors: A. Shiyovich, Y. Plakht, H. Gilutz Source Type: research

One-carbon metabolism markers are associated with cardiometabolic risk factors
Alterations to one-carbon metabolism, especially elevated plasma homocysteine (Hcy), have been suggested to be both a cause and a consequence of the metabolic syndrome (MS). A deeper understanding of the role of other one-carbon metabolites in MS, including s-adenosylmethionine (SAM), s-adenosylhomocysteine (SAH), and the methylation capacity index (SAM:SAH ratio) is required. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 3, 2018 Category: Nutrition Authors: M.V. Lind, L. Lauritzen, H. Vestergaard, T. Hansen, O. Pedersen, M. Kristensen, A.B. Ross Source Type: research

Possible trends in incidence of diabetes in Italy
(Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 3, 2018 Category: Nutrition Authors: Hoyer A, T önnies T, Brinks R Source Type: research

Association between habitual coffee consumption and metabolic syndrome in type 1 diabetes
In the general population, habitual coffee consumption is inversely associated with the metabolic syndrome, a syndrome that is rather common also in patients with type 1 diabetes. However, whether coffee intake is beneficially related to the metabolic syndrome also in type 1 diabetes, is not known. We, therefore, studied the potential association between coffee consumption and the metabolic syndrome in a large population of individuals with type 1 diabetes. Furthermore, we investigated whether coffee consumption is associated with insulin resistance (estimated glucose disposal rate, eGDR), kidney function (estimated glomer...
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 3, 2018 Category: Nutrition Authors: B. Stutz, A.J. Ahola, V. Harjutsalo, C. Forsblom, P.-H. Groop, FinnDiane Study Group Source Type: research

Serum calcium levels independently predict in-hospital mortality in patients with acute myocardial infarction
Serum calcium levels (sCa) were reported to be associated with cardiovascular risk factors, incidence of coronary artery disease and acute myocardial infarction (AMI). The current study evaluated the association between sCa and in-hospital mortality among AMI patients. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 3, 2018 Category: Nutrition Authors: Arthur Shiyovich, Ygal Plakht, Harel Gilutz Source Type: research

Ultrasound-assessed visceral fat and associations with glucose homeostasis and cardiovascular risk in clinical practice
Despite the lack of evidence that assessing the global cardiovascular risk leads to a decreased incidence of cardiovascular events, accurate patient profiling is paramount in preventive medicine. An excess of visceral fat (VF) is associated with an enhanced cardiovascular risk; importantly, VF is quantifiable rapidly, cheaply and safely by ultrasound, which makes it suitable for use in clinical practice. In the present study, we aimed to evaluate if US-measured VF (USVF) could be a better predictor of glucose homeostasis and cardiovascular risk than simple anthropometric measures. (Source: Nutrition, Metabolism, and Cardio...
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 2, 2018 Category: Nutrition Authors: M. Bellan, M. Menegatti, C. Ferrari, G.P. Carnevale Schianca, M. Pirisi Source Type: research

High serum levels of C-reactive protein (CRP) predict beneficial decrease of visceral fat in obese females after sleeve gastrectomy
Gender-related differences represent an emerging investigation field to better understand obesity heterogeneity and paradoxically associated cardiovascular (CV) risk. Here, we investigated if high-sensitivity C-reactive protein (hs-CRP) might differently affect adiposity and predict the clinical response to bariatric surgery in obese males and females. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 2, 2018 Category: Nutrition Authors: F. Carbone, E. Nulli Migliola, A. Bonaventura, A. Vecchi é, S. De Vuono, M.A. Ricci, G. Vaudo, M. Boni, F. Dallegri, F. Montecucco, G. Lupattelli Source Type: research

Ultrasound-assessed visceral fat and associations with glucose homeostasis and cardiovascular risk in clinical practice
Despite the lack of evidence that assessing the global cardiovascular risk leads to a decreased incidence of cardiovascular events, accurate patient profiling is paramount in preventive medicine. An excess of visceral fat (VF) is associated with an enhanced cardiovascular risk; importantly, VF is quantifiable rapidly, cheaply and safely by ultrasound, which makes it suitable for use in clinical practice. In the present study, we aimed to evaluate if US-measured VF (USVF) could be a better predictor of glucose homeostasis and cardiovascular risk than simple anthropometric measures. (Source: Nutrition, Metabolism, and Cardio...
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 2, 2018 Category: Nutrition Authors: Bellan M, Menegatti M, Ferrari C, Carnevale Schianca GP, M. Pirisi Source Type: research

High serum levels of C-reactive protein (CRP) predict beneficial decrease of visceral fat in obese females after sleeve gastrectomy
Gender-related differences represent an emerging investigation field to better understand obesity heterogeneity and paradoxically associated CV risk. Here, we investigated if high-sensitivity C-reactive protein (hs-CRP) might differently affect adiposity and predict the clinical response to bariatric surgery in obese males and females. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 2, 2018 Category: Nutrition Authors: F. Carbone, E. Nulli Migliola, A. Bonaventura, A. Vecchi é, S. De Vuono, M.A. Ricci, G. Vaudo, M. Boni, F. Dallegri, F. Montecucco, G. Lupattelli Source Type: research

Eat healthy? Attitudes of the German population towards industrially produced cardioprotective food
Cardiovascular disease (CVD) is likely to increase in incidence. Foods with cardioprotective functions, e.g. specific functional food, could reduce CVD risk factors and hence CVD incidence. Little is known about industrially modified foods with cardioprotective functions. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 1, 2018 Category: Nutrition Authors: F.U.C.E. Jung, C. Luck-Sikorski, M. Kr üger, C. Wiacek, P.G. Braun, S. Engeli, S.G. Riedel-Heller Source Type: research

Lipoprotein-associated phospholipase A ₂ activity is increased in patients with definite familial hypercholesterolemia compared with other forms of hypercholesterolemia
Lipoprotein-associated phospholipase A2 (Lp-PLA2) plays a key role in atherosclerosis development. It is considered a marker of increased risk of cardiovascular disease (CVD) and plaque vulnerability. Familial hypercholesterolemia (FH) is a genetic disorder characterized by elevated plasma levels of low-density lipoprotein cholesterol and a higher prevalence of early CVD.Our aim was to evaluate the differences in Lp-PLA2 activity in a population of hypercholesterolemic patients with and without definite FH. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 1, 2018 Category: Nutrition Authors: A. Mattina, D. Rosenbaum, R. Bittar, D. Bonnefont-Rousselot, D. Noto, M. Averna, E. Bruckert, P. Giral Source Type: research

Lipoprotein-associated phospholipase A ₂ activity is increased in patients with definite familial hypercholesterolemia compared with other forms of hypercholesterolemia
Lipoprotein-associated phospholipase A2 (Lp-PLA2) plays a key role in atherosclerosis development. It is considered a marker of increased risk of cardiovascular disease (CVD) and plaque vulnerability. Familial hypercholesterolemia (FH) is a genetic disorder characterized by elevated plasma levels of low-density lipoprotein cholesterol and a higher prevalence of early CVD. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 1, 2018 Category: Nutrition Authors: Alessandro Mattina, David Rosenbaum, Randa Bittar, Dominique Bonnefont-Rousselot, Davide Noto, Maurizio Averna, Eric Bruckert, Philippe Giral Source Type: research

Eat healthy? Attitudes of the German population towards industrially produced cardioprotective food
Cardiovascular disease (CVD) is likely to increase in incidence. Foods with cardioprotective functions, e.g.specific functional food, could reduce CVD risk factors and hence CVD incidence. Little is known about industrially modified foods with cardioprotective functions. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - February 1, 2018 Category: Nutrition Authors: Franziska Jung, Claudia Luck-Sikorski, Marcus Kr üger, Claudia Wiacek, Peggy G. Braun, S. Engeli, Steffi G. Riedel-Heller Source Type: research