Under-prescription of statins in patients with non-alcoholic fatty liver disease
Non-alcoholic fatty liver disease (NAFLD) is a common disease associated with high cardiovascular risk. Management of dyslipidaemia plays a pivotal role in the prevention of CV events and statins have proved to be safe in these patients. However, in everyday clinical practice statin prescription is sometimes limited because of the concern of physicians about side-effects. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - September 27, 2016 Category: Nutrition Authors: Maria Del Ben, Francesco Baratta, Licia Polimeni, Daniele Pastori, Lorenzo Loffredo, Maurizio Averna, Francesco Violi, Francesco Angelico Source Type: research

Comparison of metabolic changes between short and non-short stature, obese, low-income women after weight loss.
(Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - September 27, 2016 Category: Nutrition Authors: Nassib B. Bueno, Telma MMT. Florencio, Fabiana A. Cavalcante, Isabela L. Lins, Ana G. Clemente, Ricardo C. Sesso, Ana L. Sawaya Tags: Letter to the Editor Source Type: research

Renal Function and Carotid Atherosclerosis in Adults with no Known Kidney Disease
A high prevalence of atherosclerotic lesions characterizes patients with chronic kidney disease, though there is little data on the relationship between kidney function and atherosclerotic changes in the healthy population or in people with no known renal impairment. The aim of our study was to analyze, in a comprehensive general population with no known kidney disease, the relationship between renal function and subclinical carotid atherosclerotic damage. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - September 27, 2016 Category: Nutrition Authors: Silvio Buscemi, Giulio Geraci, Fatima Maria Massenti, Carola Buscemi, Flavia Costa, Claudio D ’Orio, Giuseppe Rosafio, Chiara Buscemi, Vincenza Maniaci, Gaspare Parrinello Source Type: research

Additional Predictive Value of Nutritional Status in the Prognostic Assessment of Heart Failure Patients
Nutritional status (NS) is not routinely assessed in HF. We sought to evaluate whether NS may be additive to a comprehensive pre-discharge evaluation based on a clinical score that includes BMI (MAGGIC) and on an index of functional capacity (six minute walking test, 6mWT) in HF patients. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - September 22, 2016 Category: Nutrition Authors: Maria Teresa La Rovere, Roberto Maestri, Francesca Olmetti, Vincenzo Paganini, Giorgio Riccardi, Roberto Riccardi, Gian Domenico Pinna, Egidio Traversi Source Type: research

Reply from the authors to “Comments on ‘Insulin resistance, postprandial GLP-1 and adaptive immunity are the main predictors of NAFLD in a homogeneous population at high cardiovascular risk’”
We thank Dr. Sani and Dr. Ayubi for their interest in our article entitled “Insulin resistance, postprandial GLP-1 and adaptive immunity are the main predictors of NAFLD in a homogeneous population at high cardiovascular risk” [1]. In their Letter to the Editor [2], Dr. Sani and Dr. Ayubi, while stating that the statistical method used in our study is correct, report t he criticisms related to the use of stepwise multiple regression as being frequently driven by statistics more than by clinical judgement. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - September 21, 2016 Category: Nutrition Authors: G. Annuzzi, L. Bozzetto, M. Mancini, A.A. Rivellese Tags: Letter to the Editor Source Type: research

Reply Letter
We thank Dr. Sani and Dr. Ayubi for their interest in our article entitled “Insulin resistance, postprandial GLP-1 and adaptive immunity are the main predictors of NAFLD in a homogeneous population at high cardiovascular risk” [1]. In their Letter to the Editor [2], Dr. Sani and Dr. Ayubi, while stating that the statistical method used in our study is correct, report t he criticisms related to the use of stepwise multiple regression as being frequently driven by statistics more than by clinical judgement. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - September 21, 2016 Category: Nutrition Authors: G. Annuzzi, L. Bozzetto, M. Mancini, A.A. Rivellese Tags: Letter to the Editor Source Type: research

Letter to the Editor - Authors' Reply
(Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - September 21, 2016 Category: Nutrition Authors: Giovanni Annuzzi, Lutgarda Bozzetto, Marcello Mancini, Angela Albarosa Rivellese Tags: Letter to the Editor Source Type: research

Incidence, prevalence, costs and quality of care of type 1 diabetes in Italy, age 0 –29 years: The population-based CINECA-SID ARNO Observatory, 2002–2012
To assess temporal trend in incidence (2003 –12) and prevalence (2002–12) of type 1 diabetes in children and young adults, direct costs and selected indicators of quality of care under the coverage of the universalistic Italian National Health System (NHS). (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - September 20, 2016 Category: Nutrition Authors: G. Bruno, E. Pagano, E. Rossi, S. Cataudella, M. De Rosa, G. Marchesini, R. Miccoli, O. Vaccaro, E. Bonora Source Type: research

Incidence, prevalence, costs and quality of care of type 1 diabetes in italy, age 0-29 years: the population-based arno observatory, 2002-2012
to assess temporal trend in incidence (2003-12) and prevalence (2002-12) of type 1 diabetes in children and young adults, direct costs and selected indicators of quality of care under the coverage of the universalistic Italian National Health Service (NHS). (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - September 20, 2016 Category: Nutrition Authors: Graziella Bruno, Eva Pagano, Elisa Rossi, Salvatore Cataudella, Marisa De Rosa, Giulio Marchesini, Roberto Miccoli, Olga Vaccaro, Enzo Bonora, ARNO Diabetes Observatory Source Type: research

Serum 25-Hydroxyvitamin D, Non-Alcoholic Fatty Liver Disease and Type 2 Diabetes
(Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - September 20, 2016 Category: Nutrition Authors: Mohsen Afarideh, Alireza Ghajar, Sina Noshad, Mohammad Saadat, Elias Khajeh, Alireza Esteghamati Tags: Letter to the Editor Source Type: research

Chronic kidney disease and high eGFR according to body composition phenotype in adults with normal BMI
Body composition contributes to the risk of chronic kidney disease (CKD) and glomerular hyperfiltration. In adults with normal body mass index (BMI), the relationships of body composition with CKD and high estimated glomerular filtration rate (eGFR) are largely unknown. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - September 17, 2016 Category: Nutrition Authors: Y.Y. Hyun, K.B. Lee, E.J. Rhee, C.Y. Park, Y. Chang, S. Ryu Source Type: research

Homocysteine Concentration in Coronary Artery Disease: Influence of Three Common Single Nucleotide Polymorphisms
Whether single nucleotide polymorphisms (SNPs) of homocysteine metabolism enzymes influence the rate of cardiovascular (CV) events in coronary artery disease (CAD) patients remains controversial. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - September 17, 2016 Category: Nutrition Authors: C. Bickel, R.B. Schnabel, E. Zengin, E. Lubos, H. Rupprecht, K. Lackner, C. Proust, D. Tregouet, S. Blankenberg, D. Westermann, C. Sinning Source Type: research

Lipophilic index, Kidney Function, and Kidney Function Decline
Unhealthy dietary fats are associated with faster kidney function decline. The cell membrane composition of phospholipid fatty acids (FAs) is a determinant of membrane fluidity and rheological properties. These properties, which have been linked to kidney damage, are thought to be reflected by the lipophilic index (LI). We prospectively investigated the associations of LI with kidney function and its decline. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - September 16, 2016 Category: Nutrition Authors: Hong Xu, Johan Ärnlöv, Bo Sandhagen, Ulf Risérus, Bengt Lindholm, Lars Lind, Juan Jesús Carrero Source Type: research

Advances in the non-invasive assessment of vascular dysfunction in metabolic syndrome and diabetes: focus on endothelium, carotid mechanics and renal vessels
The present paper is a selective review on the methodology and clinical significance of techniques to assess specifically endothelial function, carotid mechanics and renal vascular function, particularly in the light of vascular dysfunction in metabolic syndrome and type 2 diabetes. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - September 15, 2016 Category: Nutrition Authors: R.M. Bruno, K.D. Reesink, L. Ghiadoni Tags: Systematic Reviews and Meta-analyses Source Type: research

Editorial Board
(Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - September 13, 2016 Category: Nutrition Source Type: research

Which is the main molecular target responsible for the cardiovascular benefits in the empa-reg outcome trial? A journey through the kidney, the heart and other interesting places
The results of EMPA-REG-OUTCOME trial on type 2 diabetic patients at high risk for prior cardiovascular events showed that empagliflozin produces a remarkable reduction in the rates of hospitalization for heart failure (35%), cardiovascular death (38%), and all-cause death (32%). This unexpected cardio-protective action cannot be accounted for by the improvement of “classical” cardiovascular risk factors. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - September 10, 2016 Category: Nutrition Authors: Michaela Luconi, Laura Raimondi, Alessandra Di Franco, Edoardo Mannucci Tags: Review Source Type: research

Low fructosamine and mortality – a long term follow-up of 215,011 non-diabetic subjects in the Swedish AMORIS study
In this study we aim to evaluate if low fructosamine is also associated with increased mortality in non-diabetic subjects. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - September 2, 2016 Category: Nutrition Authors: H åkan Malmström, Per E. Wändell, Martin J. Holzmann, Johan Ärnlöv, Ingmar Jungner, Niklas Hammar, Göran Walldius, Axel C. Carlsson Source Type: research

Clinical worthlessness of genetic prediction of common forms of diabetes mellitus and related chronic complications. A position Statement of the Italian Society of Diabetology
(Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - August 25, 2016 Category: Nutrition Authors: Raffaella Buzzetti, Sabrina Prudente, Massimiliano Copetti, Marco Dauriz, Simona Zampetti, Monia Garofolo, Giuseppe Penno, Vincenzo Trischitta Tags: Review Source Type: research

Intracellular and extracellular miRNome deregulation in cellular models of NAFLD or NASH: clinical implications
Nonalcoholic fatty liver disease (NAFLD) represents the most common chronic liver disease in industrialized countries. NAFLD has the potential to progress through the inflammatory phase of nonalcoholic steatohepatitis (NASH) to fibrosis, cirrhosis, and hepatocellular carcinoma. Identifying patients at risk for this transition is a relevant clinical challenge. The complexity of these phenotypes in vivo made necessary the development of in vitro models in order to dissect the molecular signalling affected in NAFLD and NASH, but also to identify potential circulating biomarkers. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - August 21, 2016 Category: Nutrition Authors: S. Di Mauro, M. Ragusa, F. Urbano, A. Filippello, A. Di Pino, A. Scamporrino, A. Pulvirenti, A. Ferro, A.M. Rabuazzo, M. Purrello, F. Purrello, S. Piro Source Type: research

Intake of different types of dairy and its prospective association with risk of type 2 diabetes: the Rotterdam Study
This study aimed to investigate the impact of the full-range of dairy products and its association with incidence T2DM in Dutch adults aged ≥55 years participating in the Rotterdam Study. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - August 10, 2016 Category: Nutrition Authors: Elske M. Brouwer-Brolsma, Geertruida J. van Woudenbergh, Stefanie JWH. Oude Elferink, C écile M. Singh-Povel, Albert Hofman, Abbas Dehghan, Oscar H. Franco, Edith JM. Feskens Source Type: research

Editorial Board
(Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - August 9, 2016 Category: Nutrition Source Type: research

Renin –angiotensin system at the crossroad of hypertension and hypercholesterolemia
The aim of this study is to discuss the reliable scientific evidence of an interactive link between hypertension and hypercholesterolemia considering the metabolic pathways and the pathogenetic mechanisms connecting the two risk factors. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - August 6, 2016 Category: Nutrition Authors: C. Borghi, R. Urso, A.F. Cicero Tags: Review Source Type: research

Cardiometabolic disease in South Asians: a global health concern in an expanding population
Cardiovascular disease (CVD) is one of the main causes of mortality and morbidity worldwide. As an emerging population, South Asians (SAs) bear a disproportionately high burden of CVD relative to underlying classical risk factors, partly attributable to a greater prevalence of insulin resistance and diabetes and distinct genetic and epigenetic influences. While the phenotypic distinctions between SAs and other ethnicities in CVD risk are becoming increasingly clear, the biology of these conditions remains an area of active investigation, with emerging studies involving metabolism, genetic variation and epigenetic modifiers...
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - August 6, 2016 Category: Nutrition Authors: Avash Das, Bharath Ambale-Venkatesh, Joao A.C. Lima, Jane E. Freedman, Aferdita Spahillari, Ranendra Das, Saumya Das, Ravi V. Shah, Venkatesh L. Murthy Tags: Review Source Type: research

Renin-angiotensin system at the crossroad of hypertension and hypercholesterolemia
to discuss the reliable scientific evidence of an interactive link between hypertension and hypercholesterolemia considering the metabolic pathways and the pathogenetic mechanisms connecting the two risk factors. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - August 6, 2016 Category: Nutrition Authors: C. Borghi, R. Urso, A.F. Cicero Tags: Review Source Type: research

Switching from twice-daily glargine or detemir to once-daily degludec improves glucose control in type 1 diabetes. An observational study
Degludec is an ultralong-acting insulin analog with a flat and reproducible pharmacodynamic profile. As some patients with type 1 diabetes (T1D) fail to achieve 24-hour coverage with glargine or detemir despite twice-daily injections, we studied the effect of switching T1D patients from twice-daily glargine or detemir to degludec. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - August 6, 2016 Category: Nutrition Authors: S. Galasso, A. Facchinetti, B.M. Bonora, V. Mariano, F. Boscari, E. Cipponeri, A. Maran, A. Avogaro, G.P. Fadini, D. Bruttomesso Source Type: research

Effect of Omega-3 Fatty Acid Supplementation on Arterial Elasticity in Patients with Familial Hypercholesterolaemia on Statin Therapy
Increased arterial stiffness is closely linked with raised blood pressure that contributes substantially to enhanced risk of coronary heart disease in high risk individuals with familial hypercholesterolaemia (FH). Omega-3 fatty acid ( ω3-FA) supplementation has been demonstrated to lower blood pressure in subjects with a high cardiovascular disease risk. Whether ω3-FA supplementation improves arterial stiffness in FH subjects, on background statin therapy, has yet to be investigated. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - August 3, 2016 Category: Nutrition Authors: D.C. Chan, J. Pang, P.H.R. Barrett, D.R. Sullivan, T.A. Mori, J.R. Burnett, F.M. van Bockxmeer, G.F. Watts Source Type: research

Editorial Board
(Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 27, 2016 Category: Nutrition Source Type: research

Impact of omega-3 polyunsaturated fatty acids on vascular function and blood pressure: relevance for cardiovascular outcomes
To overview the effects of omega-3 polyunsaturated fatty acids (PUFA) on blood vessels and blood pressure and their relevance for cardiovascular prevention. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 27, 2016 Category: Nutrition Authors: G. Colussi, C. Catena, M. Novello, N. Bertin, L.A. Sechi Tags: Review Source Type: research

Hypolipidemic drugs in elderly subjects: Indications and limits
Cardiovascular disease is a major cause of death worldwide. Safety and efficacy of lipid lowering therapy have been clearly established for either primary and secondary prevention of cardiovascular events in adults. Nevertheless, the use of hypolipidemic drugs in elderly individuals, especially in the oldest ones, still raises some concerns. Aim of this paper is to review indications and limits of lipid lowering in advanced age, furnishing a practical medical attitude tempered by clinical and geriatric competences. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 21, 2016 Category: Nutrition Authors: Katia Gazzola, Giovanni B. Vigna Tags: Review Source Type: research

Higher protein intake is associated with increased risk for incident end-stage renal disease among blacks with diabetes in the Southern Community Cohort Study
Diabetes, a risk factor for end-stage renal disease (ESRD), is associated with impaired protein metabolism. We investigated whether protein intake is associated with ESRD and whether the risk is higher among blacks with diabetes. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 21, 2016 Category: Nutrition Authors: R. Malhotra, K.L. Cavanaugh, W.J. Blot, T.A. Ikizler, L. Lipworth, E.K. Kabagambe Source Type: research

Dietary fat intake modifies the influence of the FTO rs9939609 polymorphism on adiposity in adolescents; the HELENA cross-sectional study
The fat mass and obesity associated gene (FTO) has been associated with obesity and dietary intake. The aims were: (i) To assess whether energy and macronutrient intakes were different across the FTO rs9939609 genotypes in adolescents, and (ii) to explore whether dietary fat intake modified the association of the rs9939609 polymorphism with adiposity. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 21, 2016 Category: Nutrition Authors: I. Labayen, J.R. Ruiz, I. Huybrechts, F.B. Ortega, L. Arenaza, M. Gonz ález-Gross, K. Widhalm, D. Molnar, Y. Manios, S. DeHenauw, A. Meirhaegue, L.A. Moreno Source Type: research

Hypolipidemic drugs in elderly subjects: Indications and limits
Cardiovascular disease is a major cause of death worldwide. Safety and efficacy of lipid lowering therapy have been clearly established for either primary and secondary prevention of cardiovascular events in adults. Nevertheless, the use of hypolipidemic drugs in elderly individuals, especially in the oldest ones, still raises some concerns. Aim of this paper is to review indications and limits of lipid lowering in advanced age, furnishing a practical medical attitude tempered by clinical and geriatric competences. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 21, 2016 Category: Nutrition Authors: Katia Gazzola, Giovanni B. Vigna Tags: Review Source Type: research

Higher protein intake is associated with increased risk for incident end-stage renal disease among blacks with diabetes in the Southern Community Cohort Study
Diabetes, a risk factor for end-stage renal disease (ESRD), is associated with impaired protein metabolism. We investigated whether protein intake is associated with ESRD and whether the risk is higher among blacks with diabetes. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 21, 2016 Category: Nutrition Authors: R. Malhotra, K.L. Cavanaugh, W.J. Blot, T.A. Ikizler, L. Lipworth, E.K. Kabagambe Source Type: research

Dietary fat intake modifies the influence of the FTO rs9939609 polymorphism on adiposity in adolescents; the HELENA cross-sectional study
The fat mass and obesity associated gene (FTO) has been associated with obesity and dietary intake. The aims were: (i) To assess whether energy and macronutrient intakes were different across the FTO rs9939609 genotypes in adolescents, and (ii) to explore whether dietary fat intake modified the association of the rs9939609 polymorphism with adiposity. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 21, 2016 Category: Nutrition Authors: I. Labayen, J.R. Ruiz, I. Huybrechts, F.B. Ortega, L. Arenaza, M. Gonz ález-Gross, K. Widhalm, D. Molnar, Y. Manios, S. DeHenauw, A. Meirhaegue, L.A. Moreno Source Type: research

The Association of Calcium Supplementation and Incident Cardiovascular Events in the Multi-Ethnic Study of Atherosclerosis (MESA)
In this study, we examined associations between baseline calcium supplement use and incident myocardial infarction (MI) (n=208 events) and CVD events (n=641 events) over 10.3 years in men and women from the Multi-Ethnic Study of Atherosclerosis (MESA) cohort (n=6,236), with dietary calcium intake at baseline also examined as a supplementary objective. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 14, 2016 Category: Nutrition Authors: L.M. Raffield, S. Agarwal, F.C. Hsu, I.H. de Boer, J.H. Ix, D. Siscovick, M. Szklo, G.L. Burke, A.C. Frazier-Wood, D.M. Herrington Source Type: research

Baseline metabolic disturbances and the twenty-five years risk of incident cancer in a Mediterranean population.
Obesity is predictive of metabolic syndrome (metS), type 2 diabetes, cardiovascular (CV) disease and cancer. The aim of the study is to assess the risk of incident cancer connected to obesity and metS in a Mediterranean population characterized by a high prevalence of obesity. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 12, 2016 Category: Nutrition Authors: D. Noto, A.B. Cefal ù, C.M. Barbagallo, A. Ganci, G. Cavera, F. Fayer, O. Palesano, R. Spina, V. Valenti, G.I. Altieri, R. Caldarella, A. Giammanco, R. Termini, M. Burrascano, G. Crupi, A. Falletta, V. Scafidi, D. Sbordone, F. La Seta, M.R. Averna, the V Source Type: research

Challenges to the mediterranean diet at a time of economic crisis
The traditional Mediterranean diet is reportedly associated with lower risk of major chronic diseases and long considered to contribute to the reduced rates of cardiovascular and cerebrovascular events and to the highest life expectancy in adults who lived near the Mediterranean Sea.But despite its widely documented health benefits, adherence to this pattern has been rapidly declining over the last decades and a clear socioeconomic pattern has been established. According to ecological evidence, the Mediterranean Countries that used to have the highest adherence to the Mediterranean pattern in the Sixties more recently expe...
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 12, 2016 Category: Nutrition Authors: Marialaura Bonaccio, Maira Bes-Rastrollo, Giovanni de Gaetano, Licia Iacoviello Tags: Review Source Type: research

Baseline metabolic disturbances and the twenty-five years risk of incident cancer in a Mediterranean population.
Obesity is predictive of metabolic syndrome (metS), type 2 diabetes, cardiovascular (CV) disease and cancer. The aim of the study is to assess the risk of incident cancer connected to obesity and metS in a Mediterranean population characterized by a high prevalence of obesity. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 12, 2016 Category: Nutrition Authors: D. Noto, A.B. Cefalù, C.M. Barbagallo, A. Ganci, G. Cavera, F. Fayer, O. Palesano, R. Spina, V. Valenti, G.I. Altieri, R. Caldarella, A. Giammanco, R. Termini, M. Burrascano, G. Crupi, A. Falletta, V. Scafidi, D. Sbordone, F. La Seta, M.R. Averna, the Ve Source Type: research

Challenges to the mediterranean diet at a time of economic crisis
The traditional Mediterranean diet is reportedly associated with lower risk of major chronic diseases and long considered to contribute to the reduced rates of cardiovascular and cerebrovascular events and to the highest life expectancy in adults who lived near the Mediterranean Sea.But despite its widely documented health benefits, adherence to this pattern has been rapidly declining over the last decades and a clear socioeconomic pattern has been established. According to ecological evidence, the Mediterranean Countries that used to have the highest adherence to the Mediterranean pattern in the Sixties more recently expe...
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 12, 2016 Category: Nutrition Authors: Marialaura Bonaccio, Maira Bes-Rastrollo, Giovanni de Gaetano, Licia Iacoviello Tags: Review Source Type: research

Physical fitness as a mediator between objectively measured physical activity and clustered metabolic syndrome in children and adolescents: the UP & DOWN study.
The extent to which physical fitness (PF) attenuates or modifies the association between physical activity (PA) and clustered metabolic syndrome risk factors (CMetSRF) is controversial. We aimed: i) To examine the independent and combined association of objectively measured PA and PF with CMetSRF in children and adolescents; ii) To test the mediating effect of PF in the association of PA with CMetSRF. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 11, 2016 Category: Nutrition Authors: V íctor Segura-Jiménez, Fernando Parrilla-Moreno, Jorge del Rosario Fernández-Santos, Irene Esteban-Cornejo, Sonia Gómez-Martínez, David Martínez-Gómez, Ascensión Marcos, José Castro-Piñero Source Type: research

Association between a Dietary Carbohydrate Index and Cardiovascular Disease in the Sun (Seguimiento Universidad de Navarra) project
We examined the association between a carbohydrate quality index (CQI) and the risk of CVD. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 11, 2016 Category: Nutrition Authors: I. Zazpe, S. Santiago, A. Gea, M. Ruiz-Canela, S. Carlos, M. Bes-Rastrollo, M.A. Mart ínez-González Source Type: research

Lp(a) and cardiovascular risk: investigating the hidden side of the moon
This article reports current evidence on the association between Lp(a) and cardiovascular (CV) disease and on pathophysiological mechanisms. The available information on therapy for reduction of lipoprotein(a) is also discussed. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 11, 2016 Category: Nutrition Authors: Marco Bucci, Claudio Tana, Maria Adele Giamberardino, Francesco Cipollone Tags: Review Source Type: research

Genitourinary infections in diabetic patients in the new era of diabetes therapy with sodium-glucose cotransporter-2 inhibitors
To review prevalence and significance of urinary tract (UTI) and genital infections (GI) in diabetes and the effects of sodium glucose cotransporter 2 (SGLT-2) inhibitors on these complications. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 11, 2016 Category: Nutrition Authors: Marco Rizzi, Roberto Trevisan Tags: Review Source Type: research

Physical fitness as a mediator between objectively measured physical activity and clustered metabolic syndrome in children and adolescents: the UP&DOWN study.
The extent to which physical fitness (PF) attenuates or modifies the association between physical activity (PA) and clustered metabolic syndrome risk factors (CMetSRF) is controversial. We aimed: i) To examine the independent and combined association of objectively measured PA and PF with CMetSRF in children and adolescents; ii) To test the mediating effect of PF in the association of PA with CMetSRF. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 11, 2016 Category: Nutrition Authors: Víctor Segura-Jiménez, Fernando Parrilla-Moreno, Jorge del Rosario Fernández-Santos, Irene Esteban-Cornejo, Sonia Gómez-Martínez, David Martínez-Gómez, Ascensión Marcos, José Castro-Piñero Source Type: research

Association between a Dietary Carbohydrate Index and Cardiovascular Disease in the Sun (Seguimiento Universidad de Navarra) project
We examined the association between a carbohydrate quality index (CQI) and the risk of CVD. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 11, 2016 Category: Nutrition Authors: I. Zazpe, S. Santiago, A. Gea, M. Ruiz-Canela, S. Carlos, M. Bes-Rastrollo, M.A. Martínez-González Source Type: research

Lp(a) and cardiovascular risk: investigating the hidden side of the moon
This article reports current evidence on the association between Lp(a) and cardiovascular (CV) disease and on pathophysiological mechanisms. The available information on therapy for reduction of lipoprotein(a) is also discussed. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 11, 2016 Category: Nutrition Authors: Marco Bucci, Claudio Tana, Maria Adele Giamberardino, Francesco Cipollone Tags: Review Source Type: research

Genitourinary infections in diabetic patients in the new era of diabetes therapy with sodium-glucose cotransporter-2 inhibitors
To review prevalence and significance of urinary tract (UTI) and genital infections (GI) in diabetes and the effects of sodium glucose cotransporter 2 (SGLT-2) inhibitors on these complications. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 11, 2016 Category: Nutrition Authors: Marco Rizzi, Roberto Trevisan Tags: Review Source Type: research

Editorial Board
(Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 3, 2016 Category: Nutrition Source Type: research

Comments on “Impact of lifestyle interventions on depressive symptoms in individuals at-risk of, or with, type 2 diabetes mellitus: Clinical importance of lifestyle interventions”
We were interested to read the paper by Cezaretto A and colleagues published in Nutr Metab Cardiovasc Dis in Apr 2016 [1]. The authors aimed to evaluate the influence of lifestyle interventions on depressive symptoms scores in individuals at risk of or with type 2 diabetes mellitus (T2DM). They found that totally standardized mean difference (95% CI) in depression scores between control and intervention groups was −0.165 (−0.265, −0.064) and when limited to individuals with T2DM it was −0.202 (−0.288, −0.079) [1]. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - July 1, 2016 Category: Nutrition Authors: M. Sani, E. Ayubi Tags: Letter to the Editor Source Type: research