Deciphering Anion-Modulated Solvation Structure for Calcium Intercalation into Graphite for Ca-Ion Batteries
This study, for the first time, elucidates the pivotal role of anions in modulating the Ca ion solvation structures and their subsequent intercalation into graphite. Specifically, the electrostatic interactions between Ca ion and anions govern the configurations of solvated-Ca-ion in dimethylacetamide-based electrolytes and graphite intercalation compounds. Among the anions considered (BH4-, ClO4-, TFSI- and [B(hfip)4]-), the coordination of four solvent molecules per Ca ion (CN=4) leads to the highest reversible capacities and the fastest reaction kinetics in graphite. Our study illuminates the origins of the distinct Ca ...
Source: Angewandte Chemie - April 12, 2024 Category: Chemistry Authors: Yuyang Yi Youdong Xing Hui Wang Zhihan Zeng Zhongti Sun Renjie Li Huijun Lin Yiyuan Ma Xiangjun Pu Molly Meng-Jung Li Kyu-Young Park Zheng-Long Xu Source Type: research

Effect of EDTA with porous balloon on calcified lesion: An atherosclerotic cadaver study
CONCLUSION: EDTA-3Na/H2O or EDTA-2Na/H2O with longer circulation times resulted in greater calcium reduction in atherosclerotic lesion. EDTA may have a potential therapeutic option for the treatment of atherosclerotic calcified lesions.PMID:38606477 | DOI:10.1002/ccd.31052 (Source: Atherosclerosis)
Source: Atherosclerosis - April 12, 2024 Category: Cardiology Authors: Kenji Kawai Anna Madra Rika Kawakami Yu Sato Takao Konishi Tatsuya Shiraki Teruo Sekimoto Takamasa Tanaka Renu Virmani Aloke V Finn Source Type: research

Positive Vasoreactivity Testing in Pulmonary Arterial Hypertension: Therapeutic Consequences, Treatment Patterns, and Outcomes in the Modern Management Era
CONCLUSIONS: Our data display heterogeneity within the group of vasoresponders, with a large subset failing to show a sustained satisfactory clinical response to CCBs. This highlights the necessity for comprehensive reassessment during early follow-up. The use of pulmonary artery compliance in addition to current measures may better identify those likely to have a good long-term response.PMID:38606558 | DOI:10.1161/CIRCULATIONAHA.122.063821 (Source: Circulation)
Source: Circulation - April 12, 2024 Category: Cardiology Authors: Felix Gerhardt Eva Fiessler Karen M Olsson Moritz Z Kayser Gabor Kovacs Henning Gall H Ardeschir Ghofrani Roza Badr Eslam Irene M Lang Nicola Benjamin Ekkehard Gr ünig Michael Halank Tobias J Lange Silvia Ulrich Hanno Leuchte Matthias Held Hans Klose Ral Source Type: research

Resveratrol mediates mitochondrial function through the sirtuin 3 pathway to improve abnormal metabolic remodeling in atrial fibrillation
In conclusion, resveratrol ' s SIRT3-dependent pathway intervenes in AF-induced mitochondrial dysfunction, presenting a potential therapeutic avenue for AF-related metabolic disorders. This study sheds light on the role of resveratrol in mitigating AF-induced mitochondrial remodeling and highlights its potential as a novel treatment for AF. (Source: European Journal of Histochemistry)
Source: European Journal of Histochemistry - April 12, 2024 Category: Biomedical Science Authors: Yuejuan Cao, Li Cui, Shaoyong Tuo, Hongze Liu, Shaonan Cui Source Type: research

Atorvastatin reduces calcification in valve interstitial cells < i > via < /i > the NF- κB signalling pathway by promoting Atg5-mediated autophagy
In conclusion, atorvastatin inhibited the NF- κB signalling pathway by upregulating autophagy, thereby alleviating valve interstitial cell calcification, which was conducive to improving AVC. (Source: European Journal of Histochemistry)
Source: European Journal of Histochemistry - April 12, 2024 Category: Biomedical Science Authors: Menghui Chen, Su Liu Source Type: research

Association between serum calcium and prognosis in patients with acute ischemic stroke in ICU: analysis of the MIMIC-IV database
While serum Ca has proven to be a reliable predictor of mortality across various diseases, its connection with the clinical outcomes of ischemic stroke (IS) remains inconclusive. Our research aimed to explore ... (Source: BMC Anesthesiology)
Source: BMC Anesthesiology - April 12, 2024 Category: Anesthesiology Authors: Caijiao Wu, Xiaorong Li, Jiaxing Li, Ruiling Huo, Huihan Zhao and Yanping Ying Tags: Research Source Type: research

Sensors, Vol. 24, Pages 2479: The Strong Coupling Effect between Metallic Split-Ring Resonators and Molecular Vibrations in Polymethyl Methacrylate
a Han We propose and study a nanoscale strong coupling effect between metamaterials and polymer molecular vibrations using metallic split-ring resonators (SRRs). Specifically, we first provided a numerical investigation of the SRR design, which was followed by an experimental demonstration of strong coupling between mid-infrared magnetic dipole resonance supported by the SRRs fabricated on a calcium fluoride substrate and polymethyl methacrylate molecular vibrations at 1730 cm&amp;minus;1. Characterized by the anti-crossing feature and spectral splitting behaviors in the transmission spectra, these results demonstr...
Source: Sensors - April 12, 2024 Category: Biotechnology Authors: Ya Liu Esha Maqbool Zhanghua Han Tags: Article Source Type: research

Local concentration controls the hydrate phase of calcium oxalate
CrystEngComm, 2024, Accepted Manuscript DOI: 10.1039/D3CE01286G, PaperZhaodong Wang, Lala Du, Qihang Wang, Jing-Jing Xie, Zhengyi Fu, Zhaoyong Zou Non-additive factors can significantly affect the crystallization pathways and hydrate phases of calcium oxalate. However, little is known about the mechanisms behind these phenomena. Our research investigated various factors affecting... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - CrystEngComm latest articles)
Source: RSC - CrystEngComm latest articles - April 11, 2024 Category: Chemistry Authors: Zhaodong Wang Source Type: research

Non-ionotropic voltage-gated calcium channel signaling
Channels (Austin). 2024 Dec;18(1):2341077. doi: 10.1080/19336950.2024.2341077. Epub 2024 Apr 11.ABSTRACTVoltage-gated calcium channels (VGCCs) are the major conduits for calcium ions (Ca2+) within excitable cells. Recent studies have highlighted the non-ionotropic functionality of VGCCs, revealing their capacity to activate intracellular pathways independently of ion flow. This non-ionotropic signaling mode plays a pivotal role in excitation-coupling processes, including gene transcription through excitation-transcription (ET), synaptic transmission via excitation-secretion (ES), and cardiac contraction through excitation-...
Source: Channels - April 11, 2024 Category: Molecular Biology Authors: Michael Trus Daphne Atlas Source Type: research

Long-term safety of lanthanum carbonate in the real word: a 19-year disproportionality analysis from the FDA Adverse Event Reporting System
CONCLUSIONS: This study affirms lanthanum carbonate's long-term safety for reducing elevated blood phosphorus levels. While gastrointestinal disorders were common, attention must focus on emerging AEs, particularly stress, especially in elderly patients.PMID:38602862 | DOI:10.1080/14740338.2024.2343014 (Source: Expert Opinion on Drug Safety)
Source: Expert Opinion on Drug Safety - April 11, 2024 Category: Drugs & Pharmacology Authors: Mengjia Ying Jian Shi Yahao Ling Tao Shi Lele Liao Linhui Cao Source Type: research

Non-ionotropic voltage-gated calcium channel signaling
Channels (Austin). 2024 Dec;18(1):2341077. doi: 10.1080/19336950.2024.2341077. Epub 2024 Apr 11.ABSTRACTVoltage-gated calcium channels (VGCCs) are the major conduits for calcium ions (Ca2+) within excitable cells. Recent studies have highlighted the non-ionotropic functionality of VGCCs, revealing their capacity to activate intracellular pathways independently of ion flow. This non-ionotropic signaling mode plays a pivotal role in excitation-coupling processes, including gene transcription through excitation-transcription (ET), synaptic transmission via excitation-secretion (ES), and cardiac contraction through excitation-...
Source: Channels - April 11, 2024 Category: Molecular Biology Authors: Michael Trus Daphne Atlas Source Type: research

Stratified control of chemical crystallization in a pellet fluidized bed for pH-Adjusted fluoride and phosphate reduction: An experimental study
This study investigates the impact of stratified pH control in a crystallization granulation fluidized bed for the removal of fluoride and phosphate on a pilot scale. The results indicate that using dolomite as a seed crystal, employing sodium dihydrogen phosphate (SDP) and calcium chloride as crystallizing agents, and controlling the molar ratio n(F):n(P):n(Ca) = 1:5:10 with an upflow velocity of 7.52 m/h, effectively removes fluoride and phosphate. Stratified pH control-maintaining weakly acidic conditions (pH = 6-7) at the bottom and weakly alkaline conditions (pH = 7-8) at the top-facilitates the induction of fluoroapa...
Source: Environmental Research - April 11, 2024 Category: Environmental Health Authors: Ruizhu Hu Shichang Li Kaihong Li Tinglin Huang Zenan Liu Gang Wen Source Type: research

Transient stimulation of TRPMLs enhance the functionality of hDPCs and facilitate hair growth in mice
Cell Signal. 2024 Apr 9;119:111167. doi: 10.1016/j.cellsig.2024.111167. Online ahead of print.ABSTRACTAutophagy is essential for eliminating aging and organelle damage that maintaining cellular homeostasis. However, the dysfunction of autophagy has been proven in hair loss such as AGA. Despite the crucial role of TRPML channels in regulating autophagy, their specific function in hair growth remains unclarified. To investigate the biological functions and associated molecular mechanisms of TRPMLs in hair growth, Animal experiments were conducted to confirm the function of TRLMLs activation in promoting hair growth. Subseque...
Source: Cellular Signalling - April 11, 2024 Category: Cytology Authors: Jiayi Sun Hongyan Zhang Bo Xie Yuqing Shen Yuqi Zhu Wen Xu Beilei Zhang Xiuzu Song Source Type: research

Long-term safety of lanthanum carbonate in the real word: a 19-year disproportionality analysis from the FDA Adverse Event Reporting System
CONCLUSIONS: This study affirms lanthanum carbonate's long-term safety for reducing elevated blood phosphorus levels. While gastrointestinal disorders were common, attention must focus on emerging AEs, particularly stress, especially in elderly patients.PMID:38602862 | DOI:10.1080/14740338.2024.2343014 (Source: Expert Opinion on Drug Safety)
Source: Expert Opinion on Drug Safety - April 11, 2024 Category: Drugs & Pharmacology Authors: Mengjia Ying Jian Shi Yahao Ling Tao Shi Lele Liao Linhui Cao Source Type: research