Acrolein-induced apoptosis of smooth muscle cells through NEAT1-Bmal1/Clock pathway and a protection from asparagus extract.
In this study, we demonstrated that VSMCs apoptosis induced by acrolein was associated with downregulation of NEAT1 and Bmal1/Clock. AE alleviated the effects of proapoptotic response and circadian disorders caused by acrolein, which shed a new light on cardiovascular protection.
PMID: 31864078 [PubMed - as supplied by publisher] (Source: Environmental Pollution)
Source: Environmental Pollution - December 15, 2019 Category: Environmental Health Authors: Chen L, Wu X, Zeb F, Huang Y, An J, Jiang P, Chen A, Xu C, Feng Q Tags: Environ Pollut Source Type: research
Phytochemical screening and anti-implantation activity of Asparagus africanus root extract in female Sprague–Dawley rats
In conclusion, the aqueous extract A. africanus has anti-implantation effect in female rats and is safe up to 2000 mg/kg bw. In addition, it contains some potential steroidal saponins, which could be used to explain its an ti-implantation activity, however this finding needs further pharmacological studies to confirm the antifertility activities. (Source: Revista Brasileira de Farmacognosia)
Source: Revista Brasileira de Farmacognosia - December 9, 2019 Category: Drugs & Pharmacology Source Type: research
A novel process for asparagus polyphenols utilization by ultrasound assisted adsorption and desorption using resins.
Abstract
The ultrasound assisted purification of asparagus polyphenols by adsorption and desorption on the macroporous resins was investigated. The ultrasound within the selected intensities (12-120 W) and temperatures (25-35 °C) increased the adsorption and desorption capacities of asparagus polyphenols on D101 resins. Higher ultrasound intensity (120 W) and lower temperature (25 °C) benefited the adsorption process and the adsorption capacity of total polyphenols after ultrasound was 3.95 mg/g, which was 2 times than that obtained after shaking at 120 rpm. Meanwhile, ultrasound can significantly ...
Source: Ultrasonics Sonochemistry - December 8, 2019 Category: Chemistry Authors: Yu Q, Fan L, Li J Tags: Ultrason Sonochem Source Type: research
Characterization of Metabolite Profiles of White and Green Spears of Asparagus officinalis L. from Caoxian, North China
This study will help to improve the protection of Caoxian asparagus geographical indication.Graphical abstract (Source: Food Research International)
Source: Food Research International - December 4, 2019 Category: Food Science Source Type: research
GSE141012 Comparative transcriptome analysis of Asparagus officinalis and A. kiusianus in response to Phomopsis asparagi
We report the application of high-throughput transcriptome profiling of susceptible A. officinalis and resistant wild A. kiusianus 24 and 48 hour post-inoculated (24 hpi anf 48 hpi) with P. asparagi infection. (Source: GEO: Gene Expression Omnibus)
Source: GEO: Gene Expression Omnibus - November 26, 2019 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Asparagus kiusianus Asparagus officinalis Source Type: research
Concentrations of nine bisphenol analogues in food purchased from Catalonia (Spain): Comparison of canned and non-canned foodstuffs.
Abstract
The present study was aimed at assessing the exposure of an adult population to nine BPs analogues (BPA, BPS, BPF, BPB, BPAF, BPZ, BPE, BPAP and BPP) through a duplicate diet study. Up to 40 canned and non-canned food samples were purchased from Tarragona (Catalonia, Spain) and further analyzed. Three of the nine BPs - BPA, BPB and BPE - were detected in the food samples. BPA was found in 93% and 36% of canned and non-canned samples, respectively, with a mean concentration of 22.49 and 4.73 μg/kg, respectively. Only one sample of canned asparagus (88.66 μg/kg) exceeded the new threshold set ...
Source: Food and Chemical Toxicology - November 20, 2019 Category: Food Science Authors: González N, Cunha SC, Ferreira R, Fernandes JO, Marquès M, Nadal M, Domingo JL Tags: Food Chem Toxicol Source Type: research
Triterpenes and Phenolic Compounds from Asparagus burjaticus
(Source: Chemistry of Natural Compounds)
Source: Chemistry of Natural Compounds - November 15, 2019 Category: Chemistry Source Type: research
Sarsasapogenin: A steroidal saponin from Asparagus racemosus as multi target directed ligand in Alzheimer’s Disease
Publication date: Available online 28 October 2019Source: SteroidsAuthor(s): Priya Kashyap, Kalaivani Muthusamy, Manisha Niranjan, Shweta Trikha, Suresh KumarAbstractAlzheimer’s Disease (AD) is multi-factorial disorder characterized by impaired memory and cognition deficit. AD is characterized by impaired cholinergic transmission, extracellular amyloid beta deposits , neurofibillary tangles and oxidative stress. A multi-target directed ligand (MTDL) approach is required to devise a therapeutic strategy against AD. In the present study, Asparagus racemosus aqueous extract was chosen, as it possess abundant medicinal prope...
Source: Steroids - October 30, 2019 Category: Drugs & Pharmacology Source Type: research
Molecules, Vol. 24, Pages 3627: Peptidomic Approach for the Identification of Peptides with Potential Antioxidant and Anti-Hyperthensive Effects Derived From Asparagus By-Products
a
Aldo Laganà
Asparagus waste represents products of great interest since many compounds with high biological value are located in the lower portion of the spears. The extraction of bioactive compounds from asparagus by-products is therefore crucial for the purpose of adding value to these by-products. In this paper, bioactive peptides from asparagus waste were extracted, digested, purified and identified. In particular, Alcalase® was chosen as the enzyme to use to obtain protein hydrolysate due to its low cost and, consequently, the possibility of implementing the method on a large scale. In order to si...
Source: Molecules - October 7, 2019 Category: Chemistry Authors: Carmela Maria Montone Riccardo Zenezini Chiozzi Nicola Marchetti Andrea Cerrato Michela Antonelli Anna Laura Capriotti Chiara Cavaliere Susy Piovesana Aldo Lagan à Tags: Article Source Type: research
Asparagus racemosus bZIP transcription factor-regulated squalene epoxidase (ArSQE) promotes germination and abiotic stress tolerance in transgenic tobacco
In this study, we have selected root specific squalene epoxidase ArSQE from A. racemosus for its characterization. ArSQE was able to complement ergosterol auxotrophy in erg1 yeast mutants. Mutants were sensitive to the antifungal drug terbinafine, whereas ArSQE complementation made them tolerant to the same drug. ArSQE seemed to play a significant role in early germination since transgenic tobacco seedlings overexpressing the gene were tolerant to terbinafine and abiotic stress. Expression analysis of transcripts in ArSQE transgenic lines suggests that it mostly affects ABA, GA, stress, and sterol related functions in tran...
Source: Plant Science - October 2, 2019 Category: Biology Source Type: research
Structural characterisation and immunomodulatory activity of polysaccharides from white asparagus skin
Publication date: Available online 14 September 2019Source: Carbohydrate PolymersAuthor(s): Nifei Wang, Xiaojun Zhang, Shaowei Wang, Qingbin Guo, Zhenjing Li, Huanhuan Liu, Changlu WangAbstractThe physicochemical properties, structural features and immunomodulatory effects of the white asparagus (Asparagus officinalis L.) skin polysaccharides (WASP) were systematically studied. WASP showed a pectic-like structure with a relatively low degree of esterification (DE, 18%); the weight-average molecular weight (Mw) and intrinsic viscosity were 76.1 kDa and 13 mL/g, respectively. Structurally, the dominated sugar residue of ...
Source: Carbohydrate Polymers - September 15, 2019 Category: Biomedical Science Source Type: research
Preparation of starch derivatives bearing urea groups and the evaluation of antioxidant, antifungal, and antibacterial activities.
Abstract
Several starch derivatives bearing urea groups (TUCAST, MTUCAST, and PTUCAST) based on 6-O-chloroacetylated starch (CAST) were successfully designed and synthesized. FT-IR, 1H NMR spectroscopy, and elemental analysis were carried out to identify the structural characteristics of starch derivatives. The antioxidant activity of starch derivatives was tested by superoxide-radical scavenging and hydroxyl-radical scavenging assays. Their antifungal activity against Fusarium oxysporum f. sp. cucumebrium Owen, Phomopsis asparagus, and Fusarium oxysporum f. sp. niveum was estimated by hyphal measurement. ...
Source: International Journal of Biological Macromolecules - September 3, 2019 Category: Biochemistry Authors: Zhang J, Mi Y, Sun X, Chen Y, Gu G, Tan W, Li Q, Dong F, Guo Z Tags: Int J Biol Macromol Source Type: research
Asparagus (Asparagus officinalis): Processing Effect on Nutritional and Phytochemical Composition of Spear and Hard-stem Byproducts
Publication date: Available online 29 August 2019Source: Trends in Food Science & TechnologyAuthor(s): Bimal Chitrakar, Min Zhang, Benu AdhikariAbstractBackgroundAsparagus (Asparagus officinalis L.), is a well-known vegetable for its unique flavor, texture and presence of many phytochemicals and desirable physiological functions. More than 200 species of asparagus have been identified, of which, Asparagus officinalis is the only species cultivated commercially as a vegetable.Scope and approachWe have comprehensively reviewed the literature on chemical composition and phytochemicals of asparagus, with special attention to p...
Source: Trends in Food Science and Technology - August 31, 2019 Category: Food Science Source Type: research
Cytogenetic and genomic organization analyses of chloroplast DNA invasions in the nuclear genome of Asparagus officinalis L. provides signatures of evolutionary complexity and informativity in sex chromosome evolution
The transfer of chloroplast DNA into nuclear genome is a common process in plants. These transfers form nuclear integrants of plastid DNAs (NUPTs), which are thought to be driving forces in genome evolution, i... (Source: BMC Plant Biology)
Source: BMC Plant Biology - August 16, 2019 Category: Biology Authors: Shu-Fen Li, Jia-Rong Li, Jin Wang, Ran Dong, Ke-Li Jia, Hong-Wei Zhu, Ning Li, Jin-Hong Yuan, Chuan-Liang Deng and Wu-Jun Gao Tags: Research article Source Type: research
[Nutritional intervention in the control of gallstones and renal lithiasis].
Abstract
Cholelithiasis and kidney stones are frequent pathologies in developed countries. Gallstones can be pigmentary, cholesterol (75%) or mixed. Age, female sex, obesity, rapid weight loss, consumption of refined sugars, saturated fat, iron deficiency, vitamin D and low intake of fiber and vitamin C are factors associated with an increased risk of cholelithiasis. On the other hand, the intake of ω-3 fatty acids, oleic acid, calcium, magnesium, fiber, fruits and vegetables, dairy products, nuts, coffee, moderate consumption of alcohol, vitamin C supplements, physical exercise and a regular diet have a ...
Source: Nutricion Hospitalaria - July 25, 2019 Category: Nutrition Authors: Martínez García RM, Jiménez Ortega AI, Salas-González MªD, Bermejo López LM, Rodríguez-Rodríguez E Tags: Nutr Hosp Source Type: research
