Meat and bone meal stimulates microbial diversity and suppresses plant pathogens in asparagus straw composting
This study demonstrated the potential of MBM as an effective additive in asparagus straw composting, thus providing insights into the development of new industrial aerobic fermentation. (Source: Frontiers in Microbiology)
Source: Frontiers in Microbiology - September 20, 2022 Category: Microbiology Source Type: research

Ruminal fermentation and methane production in vitro, milk production, nutrient utilization, blood profile, and immune responses of lactating goats fed polyphenolic and saponin-rich plant extracts
This study was conducted to evaluate the effect of a composite plant extract (CPE) rich in polyphenolics and saponins from seeds of Dolichos biflorus (horse gram), root of Asparagus racemosus (shatavari), bark of Amoora rohituka (rohitaka), and peel of Punica granatum (pomegranate) on ruminal fermentation and methanogenesis in vitro, milk production, nutrient digestibility, immune response, and blood profiles in lactating Beetal goats fed CPE at 20 g/kg diet. Dose effect of CPE was assessed using different doses (0, 10, 20, 30, and 40 g/kg substrate) to find out an optimum dose for the in vivo study. The in vivo experiment...
Source: Environmental Science and Pollution Research International - September 10, 2022 Category: Environmental Health Authors: Sandip Shilwant Jaspal Singh Hundal Mandeep Singla Amlan Kumar Patra Source Type: research

Ruminal fermentation and methane production in vitro, milk production, nutrient utilization, blood profile, and immune responses of lactating goats fed polyphenolic and saponin-rich plant extracts
This study was conducted to evaluate the effect of a composite plant extract (CPE) rich in polyphenolics and saponins from seeds of Dolichos biflorus (horse gram), root of Asparagus racemosus (shatavari), bark of Amoora rohituka (rohitaka), and peel of Punica granatum (pomegranate) on ruminal fermentation and methanogenesis in vitro, milk production, nutrient digestibility, immune response, and blood profiles in lactating Beetal goats fed CPE at 20 g/kg diet. Dose effect of CPE was assessed using different doses (0, 10, 20, 30, and 40 g/kg substrate) to find out an optimum dose for the in vivo study. The in vivo experiment...
Source: Cell Research - September 10, 2022 Category: Cytology Authors: Sandip Shilwant Jaspal Singh Hundal Mandeep Singla Amlan Kumar Patra Source Type: research

Ruminal fermentation and methane production in vitro, milk production, nutrient utilization, blood profile, and immune responses of lactating goats fed polyphenolic and saponin-rich plant extracts
This study was conducted to evaluate the effect of a composite plant extract (CPE) rich in polyphenolics and saponins from seeds of Dolichos biflorus (horse gram), root of Asparagus racemosus (shatavari), bark of Amoora rohituka (rohitaka), and peel of Punica granatum (pomegranate) on ruminal fermentation and methanogenesis in vitro, milk production, nutrient digestibility, immune response, and blood profiles in lactating Beetal goats fed CPE at 20 g/kg diet. Dose effect of CPE was assessed using different doses (0, 10, 20, 30, and 40 g/kg substrate) to find out an optimum dose for the in vivo study. The in vivo experiment...
Source: Environmental Science and Pollution Research International - September 10, 2022 Category: Environmental Health Authors: Sandip Shilwant Jaspal Singh Hundal Mandeep Singla Amlan Kumar Patra Source Type: research

Asparagus officinalis combined with paclitaxel exhibited synergistic anti-tumor activity in paclitaxel-sensitive and -resistant ovarian cancer cells
CONCLUSION: These findings suggest that the combination of Asparagus officinalis and paclitaxel have potential clinical implications for development as a novel ovarian cancer treatment strategy.PMID:36006482 | DOI:10.1007/s00432-022-04276-8 (Source: Clin Med Res)
Source: Clin Med Res - August 25, 2022 Category: Research Authors: Xin Zhang Jiandong Wang Yali Fan Ziyi Zhao Sarah E Paraghamian Gabrielle M Hawkins Lindsey Buckingham Jillian O'Donnell Tianran Hao Hongyan Suo Yajie Yin Wenchuan Sun Weimin Kong Delin Sun Luyu Zhao Chunxiao Zhou Victoria L Bae-Jump Source Type: research

Asparagus officinalis combined with paclitaxel exhibited synergistic anti-tumor activity in paclitaxel-sensitive and -resistant ovarian cancer cells
CONCLUSION: These findings suggest that the combination of Asparagus officinalis and paclitaxel have potential clinical implications for development as a novel ovarian cancer treatment strategy.PMID:36006482 | DOI:10.1007/s00432-022-04276-8 (Source: Clin Med Res)
Source: Clin Med Res - August 25, 2022 Category: Research Authors: Xin Zhang Jiandong Wang Yali Fan Ziyi Zhao Sarah E Paraghamian Gabrielle M Hawkins Lindsey Buckingham Jillian O'Donnell Tianran Hao Hongyan Suo Yajie Yin Wenchuan Sun Weimin Kong Delin Sun Luyu Zhao Chunxiao Zhou Victoria L Bae-Jump Source Type: research

Expanding Arsenal against Neurodegenerative Diseases using Quercetin based Nanoformulations: Breakthroughs and Bottlenecks
Curr Neuropharmacol. 2022 Aug 10. doi: 10.2174/1570159X20666220810105421. Online ahead of print.ABSTRACTQuercetin (Qu), a dietary flavonoid, is obtained from many fruits and vegetables such as coriander, broccoli, capers, asparagus, onion, figs, radish leaves, cranberry, walnuts, and citrus fruits. It has proven its role as a nutraceutical owing to numerous pharmacological effects against various diseases in preclinical studies. Despite these facts, Qu and its nanoparticles are less explored in clinical research as a nutraceutical. The present review covers various neuroprotective actions of Qu against various neurodegener...
Source: Current Neuropharmacology - August 11, 2022 Category: Drugs & Pharmacology Authors: Sukriti Vishwas Rajesh Kumar Rubiya Khursheed Arya Kadukkattil Ramanunny Rajan Kumar Ankit Awasthi Leander Corrie Omji Porwal Mohammed F Arshad Mohammed Kanan Alshammari Abdulrahman A Alghitran Ashwaq N Qumayri Saif M Alkhaldi Abdulaziz Khalaf Alshammari Source Type: research

Expanding Arsenal against Neurodegenerative Diseases using Quercetin based Nanoformulations: Breakthroughs and Bottlenecks
Curr Neuropharmacol. 2022 Aug 10. doi: 10.2174/1570159X20666220810105421. Online ahead of print.ABSTRACTQuercetin (Qu), a dietary flavonoid, is obtained from many fruits and vegetables such as coriander, broccoli, capers, asparagus, onion, figs, radish leaves, cranberry, walnuts, and citrus fruits. It has proven its role as a nutraceutical owing to numerous pharmacological effects against various diseases in preclinical studies. Despite these facts, Qu and its nanoparticles are less explored in clinical research as a nutraceutical. The present review covers various neuroprotective actions of Qu against various neurodegener...
Source: Current Neuropharmacology - August 11, 2022 Category: Drugs & Pharmacology Authors: Sukriti Vishwas Rajesh Kumar Rubiya Khursheed Arya Kadukkattil Ramanunny Rajan Kumar Ankit Awasthi Leander Corrie Omji Porwal Mohammed F Arshad Mohammed Kanan Alshammari Abdulrahman A Alghitran Ashwaq N Qumayri Saif M Alkhaldi Abdulaziz Khalaf Alshammari Source Type: research

Combining Network Pharmacology and Experimental Validation to Study the Action and Mechanism of Water extract of Asparagus Against Colorectal Cancer
This study is the first to report the potential role of ASP in the treatment of colorectal cancer. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - June 14, 2022 Category: Drugs & Pharmacology Source Type: research

Biochemical and Biological Evaluation of an L-Asparaginase from Isolated Escherichia coli MF-107 as an Anti-Tumor Enzyme on MCF7 Cell Line
CONCLUSION: In this research, the proliferation of the breast cancer cells remarkably inhibited via the cytotoxic effect of isolated L-ASNase from microbial sources.PMID:35690915 (Source: Cancer Control)
Source: Cancer Control - June 12, 2022 Category: Cancer & Oncology Authors: Masoumeh Shahnazari Razieh Bigdeli Aziz Dashbolaghi Reza Ahangari Cohan Alireza Shoari Hossein Hosseini Davoud Nouri Inanlou Vahid Asgary Source Type: research

Asparagus falcatus L. (Asparagaceae) leaf extracts attenuate doxorubicin-induced renal toxicity via antioxidant, anti-inflammatory, and anti-apoptotic pathways
. (Source: Drug and Chemical Toxicology)
Source: Drug and Chemical Toxicology - May 31, 2022 Category: Toxicology Authors: Sachinthi S. Amarasiri Anoja P. Attanayake Lakmini K. B. Mudduwa Kamani A. P. W. Jayatilaka Source Type: research

Genes, Vol. 13, Pages 976: Genome-Wide Identification and Analysis of the NAC Transcription Factor Gene Family in Garden Asparagus (Asparagus officinalis)
This study provides insight into the evolution, diversity, and characterization of NAC genes in garden asparagus and will be helpful for future understanding of their biological roles and molecular mechanisms in plants. (Source: Genes)
Source: Genes - May 30, 2022 Category: Genetics & Stem Cells Authors: Caifeng Li Jingyang Zhang Qianqian Zhang Ang Dong Qiuhong Wu Xingyu Zhu Xuli Zhu Tags: Article Source Type: research

Antiobesity, Antihyperglycemic, and Antidepressive Potentiality of Rice Fermented Food Through Modulation of Intestinal Microbiota
The present study has been aimed at evaluating the antiobesity, antihyperglycemic, and antidepressive potentials of Asparagus racemosus starter-based rice fermented foods. High-throughput NGS technology has revealed a number of bacterial genera in the prepared fermented rice, such as Lactobacillus (29.44%), Brevundimonas (16.21%), Stenotrophomonas (6.18%), Pseudomonas (3.11%), Bacillus (2.88%), and others (<2%). Eight-week administration of rice fermented food has increased food intake, whole-body weight, organ weight, different fat masses, serum lipid profiles, and histology of liver and adipose tissues in HFD-induced ...
Source: Frontiers in Microbiology - May 6, 2022 Category: Microbiology Source Type: research

The Effect of Asparagus Extract on Pancreatic Cancer: An Intriguing Surprise
CONCLUSION: AE exhibits a pro-tumor effect on MDAPanc-28 pancreatic cancer cells by down-regulation of P21, P53, and FAS.PMID:35489758 | DOI:10.21873/anticanres.15721 (Source: Cell Research)
Source: Cell Research - April 30, 2022 Category: Cytology Authors: Huaping Xiao Zuliang Deng Jacob T Hough Xuhui Chen Ziwen Zhu Jacob Lee Aldo Dominguez Tianru Shi Joseph Schmidt Qian Bai Mark R Wakefield Yujiang Fang Source Type: research