Biofuels from Inulin-rich Feedstocks: A Comprehensive Review
Bioresour Technol. 2021 Dec 30:126606. doi: 10.1016/j.biortech.2021.126606. Online ahead of print.ABSTRACTBiofuels are considered as a pre-eminent alternate to fossil fuels to meet the demand of future energy supply in a sustainable manner. Conventionally, they are produced from lignocellulosic raw materials. Saccharification of lignocellulosic raw materials for bioethanol production is a cumbersome process as compared to inulin-rich feedstocks. Various inulin-rich feedstocks, viz. jerusalem artichoke, chicory, dahlia, asparagus sp., etc. has also been exploited for the production of biofuels, viz. bioethanol, acetone, but...
Source: Bioresource Technology - January 2, 2022 Category: Biotechnology Authors: R S Singh Taranjeet Singh Muhammad Hassan Christian Larroche Source Type: research
Bioactive small-molecule constituents of Lao plants
Laos has a rich plant diversity, and medicinal plants are used extensively in Lao traditional medicine for the treatment of a variety of human diseases. However, only a relatively small number of these plants have been investigated for their major components with potential antitumor, anti-infective, and other types of bioactivities. These species include Asparagus cochinchinensis, Diospyros ... (Source: Journal of Medicinal Plants Research)
Source: Journal of Medicinal Plants Research - December 22, 2021 Category: Complementary Medicine Source Type: research
In vitro antidermatophytic activity of bioactive compounds from selected medicinal plants
In this study, the antifungal activity of sixteen plant extracts was investigated against selected dermatophytic fungi. Of the sixteen plants, the cladode (leaf) of Asparagus racemosus, and seed extract of Cassia occidentalis showed antifungal activity against Microsporum gypseum, Microsporum nanum, Trichophyton mentagrophytes and Trichophyton terrestre. The plant antifungal compounds were located by direct bioassay against Cladosporium herbarum. IR and NMR spectrometry analyses of these compounds identified the presence of saponin (in A. racemosus) and hydroxy anthraquinone (in C. occidentalis) in these antifungal compoun...
Source: Anal Sci - November 8, 2021 Category: Chemistry Authors: Daisy Savarirajan V M Ramesh Arunachalam Muthaiyan Source Type: research
In vitro antidermatophytic activity of bioactive compounds from selected medicinal plants
In this study, the antifungal activity of sixteen plant extracts was investigated against selected dermatophytic fungi. Of the sixteen plants, the cladode (leaf) of Asparagus racemosus, and seed extract of Cassia occidentalis showed antifungal activity against Microsporum gypseum, Microsporum nanum, Trichophyton mentagrophytes and Trichophyton terrestre. The plant antifungal compounds were located by direct bioassay against Cladosporium herbarum. IR and NMR spectrometry analyses of these compounds identified the presence of saponin (in A. racemosus) and hydroxy anthraquinone (in C. occidentalis) in these antifungal compoun...
Source: Anal Sci - November 8, 2021 Category: Chemistry Authors: Daisy Savarirajan V M Ramesh Arunachalam Muthaiyan Source Type: research
Molecules, Vol. 26, Pages 6369: Anticancer Activity of Aqueous Extracts from Asparagus officinalis L. Byproduct on Breast Cancer Cells
In this study, aqueous extracts derived from the non-edible portion of the plant (hard stem) were prepared and characterized for chemical content. Furthermore, the biocompatibility and bioactivity of Asp aqueous extracts were assessed in vitro on normal fibroblasts and on breast cancer cell lines. Results showed no interference with fibroblast viability, while a remarkable cytostatic concentration-dependent activity, with significant G1/S cell cycle arrest, was specifically observed in breast cancer cells without apoptosis induction. Asp extracts were also shown to significantly inhibit cell migration. Further analyses sho...
Source: Molecules - October 21, 2021 Category: Chemistry Authors: Arianna Romani Fabio Casciano Claudia Stevanin Annalisa Maietti Paola Tedeschi Paola Secchiero Nicola Marchetti Rebecca Voltan Tags: Article Source Type: research
Molecules, Vol. 26, Pages 6369: Anticancer Activity of Aqueous Extracts from Asparagus officinalis L. Byproduct on Breast Cancer Cells
In this study, aqueous extracts derived from the non-edible portion of the plant (hard stem) were prepared and characterized for chemical content. Furthermore, the biocompatibility and bioactivity of Asp aqueous extracts were assessed in vitro on normal fibroblasts and on breast cancer cell lines. Results showed no interference with fibroblast viability, while a remarkable cytostatic concentration-dependent activity, with significant G1/S cell cycle arrest, was specifically observed in breast cancer cells without apoptosis induction. Asp extracts were also shown to significantly inhibit cell migration. Further analyses sho...
Source: Molecules - October 21, 2021 Category: Chemistry Authors: Arianna Romani Fabio Casciano Claudia Stevanin Annalisa Maietti Paola Tedeschi Paola Secchiero Nicola Marchetti Rebecca Voltan Tags: Article Source Type: research
Molecules, Vol. 26, Pages 6189: Standardized Extract of Asparagus officinalis Stem Attenuates SARS-CoV-2 Spike Protein-Induced IL-6 and IL-1 β Production by Suppressing p44/42 MAPK and Akt Phosphorylation in Murine Primary Macrophages
Molecules, Vol. 26, Pages 6189: Standardized Extract of Asparagus officinalis Stem Attenuates SARS-CoV-2 Spike Protein-Induced IL-6 and IL-1β Production by Suppressing p44/42 MAPK and Akt Phosphorylation in Murine Primary Macrophages
Molecules doi: 10.3390/molecules26206189
Authors:
Ken Shirato
Jun Takanari
Takako Kizaki
Excessive host inflammation following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is associated with severity and mortality in coronavirus disease 2019 (COVID-19). We recently reported that the SARS-CoV-2 spike protein S1 subunit (S1) induces pro-inflammatory re...
Source: Molecules - October 14, 2021 Category: Chemistry Authors: Ken Shirato Jun Takanari Takako Kizaki Tags: Article Source Type: research
Anticonvulsant Effect of Asparagus racemosus Willd. in a Mouse Model of Catamenial Epilepsy
Neurochem Res. 2021 Oct 8. doi: 10.1007/s11064-021-03455-2. Online ahead of print.ABSTRACTAsparagus racemosus Willd. (Family Liliaceae), also known as female reproductive tonic, is traditionally used across the Sub-Himalayan region in Uttarakhand, India for treatment of epilepsy and disorders of female reproductive system. Therefore, in this study, we investigated the anticonvulsant effect of A. racemosus in a mouse model of catamenial epilepsy. We artificially increased progesterone and neurosteroid levels (a state of pseudo-pregnancy) in adult Swiss albino female mice by injecting pregnant mares' serum gonadotropin (PMSG...
Source: Neurochemical Research - October 8, 2021 Category: Neuroscience Authors: Priyanka Pahwa Tanveer Singh Rajesh Kumar Goel Source Type: research
Asparagus racemosus and Geodorum densiflorum lectins induce apoptosis in cancer cells by altering proteins and genes expression
Int J Biol Macromol. 2021 Sep 25;191:646-656. doi: 10.1016/j.ijbiomac.2021.09.101. Online ahead of print.ABSTRACTA lectin (designated as ARL) was purified first time from the Asparagus racemosus root with the molecular weight of 14.0 kDa containing about 4.8% carbohydrate. ARL showed hemagglutination activity in both mice and human erythrocytes that were inhibited by three complex sugars among the 26 sugars tested. ARL was thermostable that mostly preserved activity at its optimum pH 8.0. Around 48% and 52.5% human colorectal cancer (HCT-116) cells growth was inhibited by 160 μg/ml of ARL and 256 μg/ml of previously puri...
Source: International Journal of Biological Macromolecules - September 28, 2021 Category: Biochemistry Authors: Syed Rashel Kabir Jahanur Islam Md Selim Ahamed Mohammad Taufiq Alam Source Type: research
Asparagus racemosus and Geodorum densiflorum lectins induce apoptosis in cancer cells by altering proteins and genes expression
Int J Biol Macromol. 2021 Sep 25:S0141-8130(21)02027-4. doi: 10.1016/j.ijbiomac.2021.09.101. Online ahead of print.ABSTRACTA lectin (designated as ARL) was purified first time from the Asparagus racemosus root with the molecular weight of 14.0 kDa containing about 4.8% carbohydrate. ARL showed hemagglutination activity in both mice and human erythrocytes that were inhibited by three complex sugars among the 26 sugars tested. ARL was thermostable that mostly preserved activity at its optimum pH 8.0. Around 48% and 52.5% colorectal cancer (HCT-116) cells growth was inhibited by 160 μg/ml of ARL and 256 μg/ml of previously ...
Source: International Journal of Biological Macromolecules - September 28, 2021 Category: Biochemistry Authors: Syed Rashel Kabir Jahanur Islam Md Selim Ahamed Mohammad Taufiq Alam Source Type: research
Asparagus racemosus and Geodorum densiflorum lectins induce apoptosis in cancer cells by altering proteins and genes expression
Int J Biol Macromol. 2021 Sep 25:S0141-8130(21)02027-4. doi: 10.1016/j.ijbiomac.2021.09.101. Online ahead of print.ABSTRACTA lectin (designated as ARL) was purified first time from the Asparagus racemosus root with the molecular weight of 14.0 kDa containing about 4.8% carbohydrate. ARL showed hemagglutination activity in both mice and human erythrocytes that were inhibited by three complex sugars among the 26 sugars tested. ARL was thermostable that mostly preserved activity at its optimum pH 8.0. Around 48% and 52.5% colorectal cancer (HCT-116) cells growth was inhibited by 160 μg/ml of ARL and 256 μg/ml of previously ...
Source: International Journal of Biological Macromolecules - September 28, 2021 Category: Biochemistry Authors: Syed Rashel Kabir Jahanur Islam Md Selim Ahamed Mohammad Taufiq Alam Source Type: research
Variation of bitter components of the asparagus juices during lactic acid bacteria fermentation
Biosci Biotechnol Biochem. 2021 Sep 10:zbab158. doi: 10.1093/bbb/zbab158. Online ahead of print.ABSTRACTTo investigate the bitterness status of asparagus juices during lactic acid fermentation, Limosilactobacillus fermentum Xd, Lacticaseibacillus paracasei Yd, Lactiplantibacillus plantarum 5-7-3 and their various combinations were used for single and mixed fermentation of asparagus juices. The fermentation characteristics and variation of the main bitter substances were studied. For the single and co-fermented samples, the viable counts, pH value and acidity were ranged from 8.33 lg CFU/mL to 8.65 lg CFU/mL, 3.58 to 3.86 a...
Source: Bioscience, Biotechnology, and Biochemistry - September 10, 2021 Category: Biochemistry Authors: Chengran Guan Yuan Yuan Wenjuan Zhang Xiangli Ding Chenchen Zhang Dawei Chen Maolin Lu Ruixia Gu Xia Chen Source Type: research
Variation of bitter components of the asparagus juices during lactic acid bacteria fermentation
Biosci Biotechnol Biochem. 2021 Sep 10:zbab158. doi: 10.1093/bbb/zbab158. Online ahead of print.ABSTRACTTo investigate the bitterness status of asparagus juices during lactic acid fermentation, Limosilactobacillus fermentum Xd, Lacticaseibacillus paracasei Yd, Lactiplantibacillus plantarum 5-7-3 and their various combinations were used for single and mixed fermentation of asparagus juices. The fermentation characteristics and variation of the main bitter substances were studied. For the single and co-fermented samples, the viable counts, pH value and acidity were ranged from 8.33 lg CFU/mL to 8.65 lg CFU/mL, 3.58 to 3.86 a...
Source: Bioscience, Biotechnology, and Biochemistry - September 10, 2021 Category: Biochemistry Authors: Chengran Guan Yuan Yuan Wenjuan Zhang Xiangli Ding Chenchen Zhang Dawei Chen Maolin Lu Ruixia Gu Xia Chen Source Type: research
Effects of ad libitum free-choice access to freshly squeezed domestic white asparagus juice on intestinal microbiota composition and universal biomarkers of immuno-metabolic homeostasis and general health in middle-aged female and male C57BL/6 mice
DISCUSSION: To the best of our knowledge, this is the first study aiming at evaluating the effect of freshly squeezed German domestic white asparagus juice on universal markers of metabolic- and liver function in middle-aged mice and the role of gut microbiota in this regard. The effectiveness of asparagus juice to improve metabolism in middle-aged mice was associated with alterations in intestinal microbiota but maybe also due to uptake of higher amounts of SCFAs. Hence, the key signal pathways corresponding to improved immune-metabolic homeostasis will be an important research scheme in the future.PMID:34463231 | DOI:10....
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - August 31, 2021 Category: Drugs & Pharmacology Authors: Darab Ghadimi Sven Olaf Frahm Christoph R öcken Michael Ebsen Andreas Schwiertz Regina F ölster-Holst Wilhelm Bockelmann Knut J Heller Source Type: research
Effects of ad libitum free-choice access to freshly squeezed domestic white asparagus juice on intestinal microbiota composition and universal biomarkers of immuno-metabolic homeostasis and general health in middle-aged female and male C57BL/6 mice
DISCUSSION: To the best of our knowledge, this is the first study aiming at evaluating the effect of freshly squeezed German domestic white asparagus juice on universal markers of metabolic- and liver function in middle-aged mice and the role of gut microbiota in this regard. The effectiveness of asparagus juice to improve metabolism in middle-aged mice was associated with alterations in intestinal microbiota but maybe also due to uptake of higher amounts of SCFAs. Hence, the key signal pathways corresponding to improved immune-metabolic homeostasis will be an important research scheme in the future.PMID:34463231 | DOI:10....
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - August 31, 2021 Category: Endocrinology Authors: Darab Ghadimi Sven Olaf Frahm Christoph R öcken Michael Ebsen Andreas Schwiertz Regina F ölster-Holst Wilhelm Bockelmann Knut J Heller Source Type: research
