Effects of ad libitum free-choice access to freshly squeezed domestic white asparagus juice on intestinal microbiota composition and universal biomarkers of immuno-metabolic homeostasis and general health in middle-aged female and male C57BL/6 mice

DISCUSSION: To the best of our knowledge, this is the first study aiming at evaluating the effect of freshly squeezed German domestic white asparagus juice on universal markers of metabolic- and liver function in middle-aged mice and the role of gut microbiota in this regard. The effectiveness of asparagus juice to improve metabolism in middle-aged mice was associated with alterations in intestinal microbiota but maybe also due to uptake of higher amounts of SCFAs. Hence, the key signal pathways corresponding to improved immune-metabolic homeostasis will be an important research scheme in the future.PMID:34463231 | DOI:10.2174/1871530321666210830150620
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - Category: Drugs & Pharmacology Authors: Source Type: research